Basic Information

Insect: Drosophila sordidula
Gene Symbol: ham
Assembly: GCA_035047465.1
Location: JAWNPQ010000090.1:4743126-4769560[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.57 37 5.0 0.0 2 21 361 380 360 383 0.87

2 9 0.021 1.4 9.5 0.7 1 23 390 413 390 413 0.92

3 9 1.8e-07 1.2e-05 25.4 1.7 1 23 419 442 419 442 0.96

4 9 3.4e-07 2.2e-05 24.6 1.5 1 23 448 470 448 470 0.97

5 9 8.6e-05 0.0056 17.0 3.8 1 23 476 498 476 498 0.97

6 9 0.0019 0.12 12.8 2.0 2 21 506 525 505 526 0.94

7 9 6.7e-09 4.3e-07 29.9 1.3 1 23 1017 1039 1017 1039 0.99

8 9 3.5e-07 2.3e-05 24.5 0.9 1 23 1045 1068 1045 1068 0.97

9 9 0.00012 0.0076 16.6 6.9 1 23 1074 1096 1074 1096 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.57	37	5.0	0.0	2	21	361	380	360	383	0.87
2	9	0.021	1.4	9.5	0.7	1	23	390	413	390	413	0.92
3	9	1.8e-07	1.2e-05	25.4	1.7	1	23	419	442	419	442	0.96
4	9	3.4e-07	2.2e-05	24.6	1.5	1	23	448	470	448	470	0.97
5	9	8.6e-05	0.0056	17.0	3.8	1	23	476	498	476	498	0.97
6	9	0.0019	0.12	12.8	2.0	2	21	506	525	505	526	0.94
7	9	6.7e-09	4.3e-07	29.9	1.3	1	23	1017	1039	1017	1039	0.99
8	9	3.5e-07	2.3e-05	24.5	0.9	1	23	1045	1068	1045	1068	0.97
9	9	0.00012	0.0076	16.6	6.9	1	23	1074	1096	1074	1096	0.99

Sequence Information

Coding Sequence: ATGTTATTCGAGAGTTTCATTATATCAGGCTCTAACGGCGACGACTACGATCCGAGCGTCGtgcgtcatcatcatcatcatcaccaccaCCTGGATCTCAGCACCGGGGCGCCGGCCTTTGGACCTTTGCCGCCGGCGCACTTGACGGCCAGCCAGGCGAGGGCCGAGGACGCCTTCGGCCGCCACCTGCCGCCCACGATAAGCCCGCCGCCAGCCACGCTGCAtccacagccgcagcagcagccgccgccgccgccgtcgcagctgcagttgcagcaacagcggctgcTGCGTTCACCGCCCGCCTCCACGTCTGCCTCGGCCTGCAGCAACGGTTCCGGTTCCGGTTCCGGTTCCGGTTCAGGAGCCGGCTCCGGCGCCAGCATGCAGCAACTGCTGAACGACAAGGCGCAGGCGGAACGCTTCCTGCTGGAGATGGCGCGCCTCCACGAACCCGTCTGTGATCTGGATATACGTGATAGCGGCGTCTACGCCAAGACACATCTGCCCCGCGGCACCCGCTACGGGCCCTTCCCCATGCGCCTCTGCCAGCAGCCCAGCGATCGCCACTTGGCCTGGGAGGTAATTGCCGGTCCGCTGTTCCACGGCTGGCTGGAGCCCTCGGCGGATGTGGCCACATGGCTGAAAAAGATACGCGCCGCGCCGAGCGAGGAAATCGAAGAGGCTAATTTACGGAATTTCATTATGGCCGGCTATctgtGGTACGAGACGAAATGCGACGTGAATGCTGGCGCCGAGATCGTGGTCGAAGCGCGCTCGCAGACGCCGTACGATATCAGCGACAGCTTCATGAACGGCAGCGCTGCgggcgcggcggcggcggcgacggcgtcggcgatggcagcggcggcgaccgtcaacagcagcagcagcagcggcaagagcaactgcaacagcagcagcaacaacaacagcagcagcctaTTGCCCGGCGACGATCGCAGCGATCGCGATAACGGCTTCTATAGCGGCGACGAATTTTCCAAGGAGAAGAAAAACTCATCGCTGACCAGCCAGGGCGAAAACGATTTCACAGACGACGAAAACGGTTTCGATATACGCTGTGAGGTCTGTGATAATGTCTATACGGACCTAGAACGCCTGGACGATCACTTGGTGGGCGCGCATCATTTCAAGCGCGGCGAATTCCCCTGCGAGCTCTGTGCCCAGCGCTTCTGCCATCGTCCTCTGCTGATCAAGCACGGCGCGATCGCCCACAATAACATAAGGAAGTACTCCTGCGAGAACTGTTCCAAGGTCTTCTGCGATCCGTCGAACCTACAGCGGCACATTCGCGCCTACCACGTCGGCGCCCGCAGCCACCCGTGCCCGGAGTGCGGCAAGACATTCGCGACCTCGTCGGGCTTGAAGCAGCACCAGCACATCCACTCCTCGGTGAAGCCGTTCGCCTGCGAGGTCTGCTTCAAGGCGTACACGCAGTTCTCCAACCTGTGCCGCCACAAGCGAATGCACGCCGACTGCCGCATGCAGATCAAGTGCAAGAAGTGCAACACGAGCTTCAGCACGGTCACCTCGCTCTCCAAGCACAAGAAGTTCTGCGACAGCTCCGACAGCTTCCGCGGCCGCCTCCACGACCACCACCATCACCAggcgcagcagcatcagcagcagtcGCATCAGCAGTCGCATCAGCAGtcgcatcagcatcagcatcagcagcagcaaccgccgccgccgccgccacttTTGCTGCCGCCCGGCGCCCATCAGCGTTtagcggccgccgccgccgtcgccgccagcAGCGAGGCGGGCACCTCTGCgatggccacgccccccaacCACCTGTTCATGATGCGGCCGACGCCCTCGTTCTTCGCCGGCTTCCCGCACTACGGCCTGCCCAACTTCTTCGCGCCCGGCCTGACGCAGGCGCCCAACTTCCAGCACATGTTCCCCGGCTCGCCCCAGCTGCTGGGCGACATGGGACGCGGCCTGGCGCCGCTCGTCTCCCCCAACGCCGccttccagcagcagctgatgggCCTCAAGGCCGACTCGCCGCGCGTGAAACGCGAGCCCAGCCCGCCCGAACCGAAGCCCATCAAGTCCGAGCTCGACGGGGATGAGTCCGACTCCACGAGCTACGACGACCCcaagctgaagctggagcCCAACAAGCTGCTCAAGCTCAAGCCGGACGCCGGCAAGGTCAAGCGCGAGGCCAGCTGCTCCCAGCCGCCCGAGGAGGACATGGACAACGACAATGATAACGACAGGAAATCCATAGATATAGTCAgcacgccgccgccggcggacGCCGAGCTGGACGTGGACCAGGACAAGGGCGGCGTGGAGCTGCCGCTGGACCTGTCCATCAGTCGCAAGCGCTGCAGTCCCACGCCCGCCCCGCTCTCCATCGCGCTGAGCAGTCGCACGCCTACGCCCGAGctggacgaggaggaggacgaggaggaggaggaggaggaggaggagggtcGGCCGCCGCCGGCGAAGCTGGCGAAGCACCACAGCTCCGGCGAGTCGTCCAACTCGCGCCAGTCGAcgcccagcgccagcgcctCGCCGGGCCTGACGCCCTCCCCCTCGCCGCCCATCAGCACCGGCGGCGAGCTGAGCAGCATGTCCGAGAGCGCGgcggccgcagcggccgccacggccacagcggcagcggcggcggcggcggcggccgcctcGGCGATGGCCTGTCCGCGGGCGCTGCatccgcagcagctgctggaggagCTCTACCGCTCGCAGTTCGCACAGCCACCGTTTCATTTTTTAGGCCAAATGGGCGGACGGCCAGGTTTTGAGTCCCTTAAGTCGCCGGCTGCGGGCGCCCACGCGCCCCTCAGCAGCTCGCGTCAACTGCCGTTTCCGCCCGAGCACAATATCCGCGAGGCGCTGCTCGCCGCCGGCCTGGCCGGCGCCTCGGTTCACAGCCATGGGCATGGCCATGGGCATGGCCATGGCCCAGGTCACGCCCAGgtccacgcccacgcccacgcccacccgcaCGCCAGCGGGAAGCTGAAGGACCGCTACACCTGCAAGTTCTGCGGCAAGGTGTTCCCGCGCTCCGCCAATCTCACGCGACACCTGCGCACGCACACCGGCGAACAGCCGTACACGTGCAAGTACTGCGATCGGGCGTTCAGCATCTCCTCGAATCTGCAGCGGCACGTGCGCAACATCCACAACAAGGAGCGGCCGTTCAAGTGCCACATGTGCGAGCGCTGCTTCGGGCAGCAGACGAATCTCGACCGGCACCTGAAGAAGCACGAGGCGGACGCCGGCGGCTTCGAGTACAACGATTCGCCCAGCTCGAACGAGGCCAACGAGCGCGACGAGGCCAGCTTCGATGACATCCGGAGCTTCATGAAGGGCGTCTACACGCCCACCAGCCAGGGCGGGGCCGACGGGGACACCGAGGAGTACGCCGGCAGCGACGATCAGCTGTCGGTGTCCACGCGCCAGTCCGCCAGCTTCGACAaggagctgctggccaacggcaacaacaacaacaacaacagcaatagcagcagcaacaacaacaacaacaacaacaaacaggcGGGTCTGGGCAAAACAATCGCCGTTAGCACCTAA
Protein Sequence: MLFESFIISGSNGDDYDPSVVRHHHHHHHHLDLSTGAPAFGPLPPAHLTASQARAEDAFGRHLPPTISPPPATLHPQPQQQPPPPPSQLQLQQQRLLRSPPASTSASACSNGSGSGSGSGSGAGSGASMQQLLNDKAQAERFLLEMARLHEPVCDLDIRDSGVYAKTHLPRGTRYGPFPMRLCQQPSDRHLAWEVIAGPLFHGWLEPSADVATWLKKIRAAPSEEIEEANLRNFIMAGYLWYETKCDVNAGAEIVVEARSQTPYDISDSFMNGSAAGAAAAATASAMAAAATVNSSSSSGKSNCNSSSNNNSSSLLPGDDRSDRDNGFYSGDEFSKEKKNSSLTSQGENDFTDDENGFDIRCEVCDNVYTDLERLDDHLVGAHHFKRGEFPCELCAQRFCHRPLLIKHGAIAHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARSHPCPECGKTFATSSGLKQHQHIHSSVKPFACEVCFKAYTQFSNLCRHKRMHADCRMQIKCKKCNTSFSTVTSLSKHKKFCDSSDSFRGRLHDHHHHQAQQHQQQSHQQSHQQSHQHQHQQQQPPPPPPLLLPPGAHQRLAAAAAVAASSEAGTSAMATPPNHLFMMRPTPSFFAGFPHYGLPNFFAPGLTQAPNFQHMFPGSPQLLGDMGRGLAPLVSPNAAFQQQLMGLKADSPRVKREPSPPEPKPIKSELDGDESDSTSYDDPKLKLEPNKLLKLKPDAGKVKREASCSQPPEEDMDNDNDNDRKSIDIVSTPPPADAELDVDQDKGGVELPLDLSISRKRCSPTPAPLSIALSSRTPTPELDEEEDEEEEEEEEEGRPPPAKLAKHHSSGESSNSRQSTPSASASPGLTPSPSPPISTGGELSSMSESAAAAAAATATAAAAAAAAAASAMACPRALHPQQLLEELYRSQFAQPPFHFLGQMGGRPGFESLKSPAAGAHAPLSSSRQLPFPPEHNIREALLAAGLAGASVHSHGHGHGHGHGPGHAQVHAHAHAHPHASGKLKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYTCKYCDRAFSISSNLQRHVRNIHNKERPFKCHMCERCFGQQTNLDRHLKKHEADAGGFEYNDSPSSNEANERDEASFDDIRSFMKGVYTPTSQGGADGDTEEYAGSDDQLSVSTRQSASFDKELLANGNNNNNNSNSSSNNNNNNNKQAGLGKTIAVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00547517;
90% Identity: -
80% Identity: -