Basic Information

Insect: Drosophila sordidapex
Gene Symbol: Hivep2
Assembly: GCA_035043295.1
Location: JAWNNA010000904.1:1565853-1574134[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0017 0.11 13.1 0.4 2 23 266 287 266 287 0.98

2 8 0.00027 0.017 15.6 3.2 1 21 293 313 293 317 0.90

3 8 0.012 0.73 10.5 0.2 1 19 972 990 972 993 0.93

4 8 3.2e-06 0.0002 21.6 2.0 1 23 1746 1768 1746 1768 0.99

5 8 1.4e-05 0.00086 19.7 5.3 1 23 1774 1798 1774 1798 0.92

6 8 0.00061 0.039 14.5 3.5 2 23 2280 2301 2280 2301 0.97

7 8 0.00093 0.059 13.9 1.2 1 23 2307 2331 2307 2331 0.91

8 8 0.003 0.19 12.3 2.7 1 23 2352 2376 2352 2376 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0017	0.11	13.1	0.4	2	23	266	287	266	287	0.98
2	8	0.00027	0.017	15.6	3.2	1	21	293	313	293	317	0.90
3	8	0.012	0.73	10.5	0.2	1	19	972	990	972	993	0.93
4	8	3.2e-06	0.0002	21.6	2.0	1	23	1746	1768	1746	1768	0.99
5	8	1.4e-05	0.00086	19.7	5.3	1	23	1774	1798	1774	1798	0.92
6	8	0.00061	0.039	14.5	3.5	2	23	2280	2301	2280	2301	0.97
7	8	0.00093	0.059	13.9	1.2	1	23	2307	2331	2307	2331	0.91
8	8	0.003	0.19	12.3	2.7	1	23	2352	2376	2352	2376	0.92

Sequence Information

Coding Sequence: ATGACGCTACAGCAGGTGGCAAGCAGCGCAACGAGCaaggtggcaacaacaacaacaataataccagccacagccaacaccacaagcaacaacaaccagaacaacaacaacaacaacagcaccagcaacaaccacaatgtgctggccaacaacaacagcagcagcgatgatccaacaacagcggcagcaataaATGTCGACGGCTGGACGAGCTCAACCACTTTGCgttatttgcacaaaaagtTTAAGCGGCTGGCGAGCACCACCGAACCGGAGTCGGTCGATACAATGGCGGCGGCGCGCACCACATCGCTGTCTTCGAATAGCTCGTTGTCGCCACCGCTGCCAGTGGCGGCTGCTCCTCTGCTCAATGGACATGTAACGGTGAAGGTTGCTCCCTTGCTGCCGGCAAGAAATTTAGAATTCAGTGCCAATTTCGTAAAtgccaacgacaacatcaacaacaataacaacagtcaTGATGAGAGCAAGCATGGCaatgttggtgttgctggtgcgCCTCGAACACGCACGCCGCTCAGCAACAGtaattgcaacagcaatattAACTATGCCAGCAATGCAACACTGTCGCCAGCAACATTcgcacagcatcagcaacaaacgcagccaacgccagcagcaacagcagccgtcgttgcaacattagcagcagcaacaacaacaacaacaacaacagcagcaacaacagcagcagcagcaacaacaacaacaacaacaataatacaaacagcagcagcaacagttgcaggaTTAGAGAAAACTAGTCGCCCCAAGTGCCCCTATTGCAATCTGATCTGCGCAAAGCCGTCTGTGCTGGAGAAGCACATTCGTGCCCACACCAATGAGCGACCGTATCCGTGCAACAACTGCGGCATCGCCTTCAAAACGAAGAGCAACCTGTACAAACACTGCCGCTCCCGTTCCCATTTGGCGCGCATGCGCGGCCTCGATGTACCGGCCAATGAGACGGACGGACTGTCCGACCAGGATGGCGATGGGGagctgagcaacagcagctccgAGCTGCTAAGCGTTGAAATTTTGAGTCGCACAGATTCGCCTTATGATGAGGCCATGGCCTCGCCCacgccatcgccatcgacGCTGTCGGCGGCAAAGAGTACGTATCTGCAACAGccgcaattgcaacagcatatgctgcaacagttgccgctgGGCTCGCCTGCCGCCGGAACACTGCCGCCCGCCCCGCCCGCTGACTCGCTGCACTCGGCAACCGCTCAGCATCGCCAGTCGCTCGACTACAAGCCATACAAGCCCAAGTTTCACAATGCAGCCCTTTATGCGCCCGGCACGctcaaggagcagcagcagcagcaggtactgcaacagcagcagacgctgctgcaaccacaacagcagccacataaACTgtcagcgcagcagcagcagcagcagcaaccatcGTTGGCGCATCCAACGCTCTCGCCCAGCACCCAGTTGAAGCTTAACAATCACATAAACTCGcatcagctgcaattgcagctgcagcatcagcaccaacagcagcagcagcatctgcacgCCCAGCAATccctgctgctggcagcggcagcaaccaATCCGGTTGCATTGTCAGCCttaccaccgccgccgccgggCGTTTATTATTTGGGACAGCCGCAGTATTATAatccaactgcagctgcaatgcATCAGCATGCGCTGGCCATTCAgcagatgcagttgcagcagcactttcagctgcaacaacagcagcaacagcatcaccaacagcagcaacagcatcagcaacaccagcaacagcagcagcagcaacaacaacaacagcagcagcagcagcagcaacaacagcagcagcagcagcagcaacaacagcagcagcagcaacaacagcagcagcagcaacattcgCCGCTGCTGAAgccgccacagcagcaacagcagcagCTGTTGCGCTCAAATAGCCAACAACAGGCGGCAGtcattgcaacaacagcatcgcTGCCTGCACCTGCTACACCCAACCCGCCTACCAATCTAAGCAGCTTTGCCAGCTCAAGCGGTGGCATGCAAGTGAATGTGGAAAAGGTGCAGGAGCACATCTCCAAGCTGATCTCACAGAACGAGGCCATTGTCGAGAACAAGGAGATACTGCTGCAGAAGAAGTATCCCAAGCAGCTGAATCGTTCGCGCAGCttcaacaatgccaacaacaataatagcagcaatggcagcaacatcaacagcagcagtataccaacaacagctcaagccaacagcaacagcagcaacaacaacagcaatcaacaGCTGGGCGAGACTAAAGTGAACCTGGCACAGGCGATAgtacaaaaacagcagcagcaacagcatatgcaacaacagctgcagcagcaacaataccaattatatttgcagcagcagcaacagcaactgcaactggagcCCCCGGTTAATGGTCTGCtgaagcgcagcagcagcagctctgcGTGCAGCTCAGCCAGCAGCGGCTATGTCAGCCTTAAGGGCACAGCAACCCCAACACCCGCCGCACCCACGGCAAGTGTgaaacagttgcaacagttgccgccgccgccatcgCCGTTGCCATTGCAACAGTTACAGTACCGCCAGGATCCGTCAACGCCAGTGCCtaagctggagcagcagctgcagttgcagcaacccTTGGCACCCAATCATGCCCAGCCTTTGAATTTGTCTGCCAAGCCCAAGCCACTAGCAATGCCAtcaaaaccaacagcaacagcagccgcagcaacaactgttggcaagatgacaacagcagcgcagGCGGCTACACCGAATATATCCATAATCAAGAATCTGCTGTTGAATGCACGTGGCTTGGCAGTGCCAATTGGCGAGGGCGATGATGCCGTCTACTCCTGCCCCATTTGCGCCAACGAGTTTCGCAGCGCGGATGAGCTGAAGCACCACAACAGCACCTACTGTCAGGATGCGAACAGCAGTGCTCCCATCAGTCCCGCCTCATCGCCGAGCAGCAAATACTTTCGCTCCAATTCCATATCGTTTAGTCTGCCGGAGCTGCAGTCGCACATGGCCAACTCGAAGAATCCGTTGTCGCTCGCCAAGCTTGCCAAGGTCGCCTGGTCGCAGCTAAAAACCAAGCCAAGCAGCCTGGTTCTCAGTCGTCTCAGTGCGGCTCAATCTCCCGCACGCACCTCAACCGTCACAGCagccaccaacagcagcagcaacaacataaacagcaacagcagcaacatcatcaatcacaacagcagcagtaatcaCATAagaacagcagcggcagcaactgttgtAATCCCGCCCAGCATTGATGCTTCCAGCGTTGCTTTGCGTTTCGTGGACGCACCGCTGCCATCGCCTGGTCCACTGCTCGGCAAGACACCGCTGGTCGATTATGCGGCGCCGCGCAAGGCTCCCGATGCCCAGGTGGTCATCACGAAAATGCACGAGGATCGCTTGGAGAACATCATCGTTGAGGCGCCATCGAAACGGCTCAAACTGAGCAGTGGCGAGACAGCGTTCACTCTTTTTGCTGGCAATCCGGATTTGCAGTTCAGTGCCAAGGAGGAGCGTCTGCGTCGCTTTACCTCATCCGGCGGCACGATGATACCCATTTCTGAGTGTCCCGAGCTGAACGAGAGTCCCAAAATGATACGCACTCCGCTGTTGTCCGGCGGCAGTTTCCAGGAGATGTCACCCCGTCTCAGCGACGTCAAGGACCGCAAACTTCtcgctgccaacaacaacaacaacaataacaataataataataataatggttTTCTGCTCAGCGCCTCAAACACGCCgcatcattttcaatttcctaTCAATTCGATAACGGCCTTCAATCCGCTCACGCTGCCACccatgagcaacagcagcggcaccaccagcagcagcagcaccagcagcatcaacaccAGCAATCTTGTGGATAAGGCAATACCCTATGTGCCGGGCATACCCGGTCCGGGCAGCTTATCGTTGCTGCCACCgccactgcagctgcagcgtgGACGCAGTCCCAATCGCAAACAGCCCAGTCCCAATTCGAATCCCAATCTCAATCTTAATCTCAATCCGCTGCTGGCAGCCGAGGGCCCGCTGAAGGCACTCTCGCCCTTCGGTGGCGTTCAGAACTTGCCCAGCGAATTCAGTCGACAGCCACCAACGCCAGCGCAGCGCAATGCGCTCCAAtggaccaacaacaacaacagcagcaacagcaacagcagcaataggtTGCCACTGATTGTGGCTGACAAGAAGCCACCATTCAATTTTCTACGCATGGCGGATAATGTGAAGAACTCCACTGTGCAGGACCAACAGCCCCCGTCTCAATCTCAATCCCAGGCAATGGGTATGCCAGAGGTGCGTCACTTTAATTTCGATAATGTGAACAAATCGCAGGAGGCGCTGGCGCCGCTGCATGTGGACACACCCGACGAGGCgactgcaacagcagtagGAGCAATcaaaacatcaacagcagcaacttctattctggcagcagcagcaacaaccacaacgagcAGTGCCAAGTCAAAGTTCTTGCGGCCCACCAGTCTGCCTCTGAAGCCGGGCACCTTTACGCCGAAGCGACATCATGGCATCACACCGACTGCGAATACACTGCCCCTAATCTCACCGGAAACGCCAAGACCCTCTAAGTCGTGCGTGCAACTGTATCTGAATGGTCACGCGTATACCTATCTGGGGCTCAAGTCCAGCACAAAGATGTTCTACTGTACGGTGAACTGTCCGCAGCCCTCGTATGTCGCTGGCATGCACAAACTGTCGATGTACAGCGTGTGGCAGGTATGCGAGGAGAATCAGCCGCATCCGCTCGGCTTCAAGCCCAAACAGGTGATGGCTCTGTACGATTCCCGGCAGAAGATGCTCGGCACTGGCTGCACCACAGCGATGGCGGGTGCCGGCAAACTGCAGTACTCCGTCTTCTGTTCACAGGAAACGGTTAGCACGAGCTCCACCACGGCCAACGGGCAAAGCAAGTTCTACCAGCACCAGCTGAAGCAGCCGCCGGCAATTGGCGCGCTCAGCGAGGCGAATGTGGCCGCCAAGGCCAGCGAGGAGGCGGCTGCCAAGAAGCTGGAGTCGAGCCAACTATTGGTCGGCGGATACGAGTCGCATGAGGATTACACGTATATTCGGGGACGAGGGCGTGGTCGCTACGTCTGCTCCGAGTGTGGCATACGTTGCAAGAAGCCCTCCATGCTCAAGAAGCACATACGCACCCACACGGATGTGCGTCCCTTCACCTGCAGTCACTGCAACTTCAGCTTCAAGACCAAGGGCAATCTTACCAAGCACATGCAGTCGAAGACGCACTTCAAGAAATGCATCGAGCTGGGCATCAATCCGGGTCCGATGCCCGCCGACGGCGAATTCCTTGATGTCGATGTGGACTTTGATCAGCAATCCTCGACATCAGCAGGCGGACGCACCTCCTCCATGGCCGGTGAATCCGATTCGGATGACTACAGCGACAACGAGTCCGAGAGCAGTGACACCGATGAGTCCAAGTCGCGCATGAAGGAGCACGAGGCAGCTCGTGgactgctgtcgctgtcgatGACGCCGCCGATACCGCAGAGTGTTTCACCGTATCCGGCACTGGTGCAGGATACGCCGGCTGCCAGTCCAGCGAACAGCATTGGCTCGTCGGCGGGCAGCGCAGCTGGCGGCTCGCAGCCGAAGCGGCAGGTGTGCTCGTTTACGTCGCCAAAGCCGCCGTTTGACTaccagaagcaggagcagtatTACTCTAATCCCGAGGAGTCTAAACCTAAGCGCGGTGTGCCTAACGACGAGAGCAGTGCACCCATGGATCTGACCAAGCCACGCCCAATGCCCAGCATTTCAGTTGCCGCCTCTTCGCCCGTGCCGGAGCAGCTGCAGATGCAGACGCCCAAATCGCAGGCACAGCAGATGCGCGACGTCATCTTTGGTGCGGGCAACAACGAGTGCGGCTTCATGAAGACCCTAATCTCTGTCTCCGATAAGGTGCGCATCTCTGCCGAAATTGAGGAGCAGGCGAAGCGCGAAAGCGAAGGCGAGGATGTCCTCCTGCAGACCTACATCAAGGAGCAGGCGCTGCAGCATGCCAAAATGAAGCAGAGCCAATTTAGCCGCAGCTACCTGGTGACCTCCACCACCAACTCCACTTCCAACTGCATCTCCGCaagctccagctgcagctccatCTCTACCACGAGCAGCATtagctgcatcagcagcagctatgtTGTGGCCACGCCCCTTGTTAATAGCAAACCACAGTTGAACATCGCGGAGCTGCCCAGCATTGAGGTGCACGAGGTGAGGACACCAGAGTCGCCAACGCCATCGCCGGCTGTTGGGCAGGCTGCCATCAAATCCGCCGAGGAGAGTGAGGAAAGCGAAACGCAATCGGATCAGGAGAAGCCAACCATAAAGTCCATTCCTGTAATTGTAACAGTACCTGCTTCAGTCACTGTGCCCGTTTCCAGCGTGGAGATTCAGCAGCCGCACAATGCCAATTTGCctgctgcagtgcagcagccAGATGCCACCGATTTTAGCGGTgtactcagcagcagcagcaacaaaaatagcagcagcagtggagcAACTGCACCCACACGTATTGTGGTCGCCGGAGAGGATGGCTTCAAGACAACTCCAACCAGTGCCAGCAACGAATTGCAGTCTGGAGGAGCACCCGCTGGAGCAACTTATACGAATCGTGTggtgccaccgccaccgccgccaatTGCGAGTGATGCGCGACCCACTTGCACCGTTTGCAACAAGACGTTCCAGCGAACGCATCAGCTGTCGCTGCACATGAACATCCACTACATGGAACGCAAGTTCAAGTGCGAGCCGTGCAGCATCTCGTTCCGTACACAGGGTCATCTGCAGAAGCACGAGCGGAGCGAGGCGCACAGGAACAAGGTGATGATGACATCGACATTTGGTGTGCCCACCACATCCAATCCGCGTCCGTTTGAGTGCACCGATTGCAAGATTGCGTTTCGCATTCACGGCCATCTGGCCAAGCATCTGCGCTCCAAGACGCATGTCCAGAAGCTGGAGTGCCTGCAGAAGCTGCCATTTGGCACCTACGCTGAGATCGAACGTGCTGGCATCAGTCTGACGGAGATCGACACCAGCGATTGTGAGAATTCGCTCATCTCGCTCAAGCTGCTGGCGCAAAAGCTGCTCGAGAAGGATCCCAACAAGCTGAGTGGCTACACAACGCCGTCGGGCATGCTGCAGCTGTCGGCAGATGCACCTGCTGCCGGCCAGGACAGCGCCTCCGAGGATGGCTTCAGTGCGGCGAACAGTGCCGCCGCCTCGGCCATTGCCTCGCTGGACAACGACAGTGCGGGCAACACACCCAAGCGGGCCAGCTCCATGTCCGAGGATGAGACGCTTACCAACGGACTCGGACTCAGTCACAGCCATGGCCACAGTCTGAAGCGGCGTCTGCAGCacagcagcttcagcagcaATGGCGATGAGAGCGACAACCCAACAGATGCCACGGCAGCGGGCACTGGCTCTGgcactggcagtggcagtgtcAGCAACGAGAAGCGTGCGAGAAGCAACACAAATGAGATCACACTGCCGACCCCGGTGGCTGTGTCAACGGCAACAGCCAGCAACTGa
Protein Sequence: MTLQQVASSATSKVATTTTIIPATANTTSNNNQNNNNNNSTSNNHNVLANNNSSSDDPTTAAAINVDGWTSSTTLRYLHKKFKRLASTTEPESVDTMAAARTTSLSSNSSLSPPLPVAAAPLLNGHVTVKVAPLLPARNLEFSANFVNANDNINNNNNSHDESKHGNVGVAGAPRTRTPLSNSNCNSNINYASNATLSPATFAQHQQQTQPTPAATAAVVATLAAATTTTTTTAATTAAAATTTTTTIIQTAAATVAGLEKTSRPKCPYCNLICAKPSVLEKHIRAHTNERPYPCNNCGIAFKTKSNLYKHCRSRSHLARMRGLDVPANETDGLSDQDGDGELSNSSSELLSVEILSRTDSPYDEAMASPTPSPSTLSAAKSTYLQQPQLQQHMLQQLPLGSPAAGTLPPAPPADSLHSATAQHRQSLDYKPYKPKFHNAALYAPGTLKEQQQQQVLQQQQTLLQPQQQPHKLSAQQQQQQQPSLAHPTLSPSTQLKLNNHINSHQLQLQLQHQHQQQQQHLHAQQSLLLAAAATNPVALSALPPPPPGVYYLGQPQYYNPTAAAMHQHALAIQQMQLQQHFQLQQQQQQHHQQQQQHQQHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHSPLLKPPQQQQQQLLRSNSQQQAAVIATTASLPAPATPNPPTNLSSFASSSGGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANNNNSSNGSNINSSSIPTTAQANSNSSNNNSNQQLGETKVNLAQAIVQKQQQQQHMQQQLQQQQYQLYLQQQQQQLQLEPPVNGLLKRSSSSSACSSASSGYVSLKGTATPTPAAPTASVKQLQQLPPPPSPLPLQQLQYRQDPSTPVPKLEQQLQLQQPLAPNHAQPLNLSAKPKPLAMPSKPTATAAAATTVGKMTTAAQAATPNISIIKNLLLNARGLAVPIGEGDDAVYSCPICANEFRSADELKHHNSTYCQDANSSAPISPASSPSSKYFRSNSISFSLPELQSHMANSKNPLSLAKLAKVAWSQLKTKPSSLVLSRLSAAQSPARTSTVTAATNSSSNNINSNSSNIINHNSSSNHIRTAAAATVVIPPSIDASSVALRFVDAPLPSPGPLLGKTPLVDYAAPRKAPDAQVVITKMHEDRLENIIVEAPSKRLKLSSGETAFTLFAGNPDLQFSAKEERLRRFTSSGGTMIPISECPELNESPKMIRTPLLSGGSFQEMSPRLSDVKDRKLLAANNNNNNNNNNNNNGFLLSASNTPHHFQFPINSITAFNPLTLPPMSNSSGTTSSSSTSSINTSNLVDKAIPYVPGIPGPGSLSLLPPPLQLQRGRSPNRKQPSPNSNPNLNLNLNPLLAAEGPLKALSPFGGVQNLPSEFSRQPPTPAQRNALQWTNNNNSSNSNSSNRLPLIVADKKPPFNFLRMADNVKNSTVQDQQPPSQSQSQAMGMPEVRHFNFDNVNKSQEALAPLHVDTPDEATATAVGAIKTSTAATSILAAAATTTTSSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKSSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKPKQVMALYDSRQKMLGTGCTTAMAGAGKLQYSVFCSQETVSTSSTTANGQSKFYQHQLKQPPAIGALSEANVAAKASEEAAAKKLESSQLLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDVDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRMKEHEAARGLLSLSMTPPIPQSVSPYPALVQDTPAASPANSIGSSAGSAAGGSQPKRQVCSFTSPKPPFDYQKQEQYYSNPEESKPKRGVPNDESSAPMDLTKPRPMPSISVAASSPVPEQLQMQTPKSQAQQMRDVIFGAGNNECGFMKTLISVSDKVRISAEIEEQAKRESEGEDVLLQTYIKEQALQHAKMKQSQFSRSYLVTSTTNSTSNCISASSSCSSISTTSSISCISSSYVVATPLVNSKPQLNIAELPSIEVHEVRTPESPTPSPAVGQAAIKSAEESEESETQSDQEKPTIKSIPVIVTVPASVTVPVSSVEIQQPHNANLPAAVQQPDATDFSGVLSSSSNKNSSSSGATAPTRIVVAGEDGFKTTPTSASNELQSGGAPAGATYTNRVVPPPPPPIASDARPTCTVCNKTFQRTHQLSLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHRNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMLQLSADAPAAGQDSASEDGFSAANSAAASAIASLDNDSAGNTPKRASSMSEDETLTNGLGLSHSHGHSLKRRLQHSSFSSNGDESDNPTDATAAGTGSGTGSGSVSNEKRARSNTNEITLPTPVAVSTATASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00513682;
90% Identity: iTF_00482470;
80% Identity: -