Basic Information

Insect: Drosophila simulans
Gene Symbol: -
Assembly: GCA_016746395.1
Location: NC:16462486-16465033[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 1.2e-05 0.00072 19.5 0.9 1 23 151 173 151 173 0.99

2 8 0.96 59 4.1 1.8 1 21 177 197 177 198 0.91

3 8 0.0083 0.51 10.5 0.7 2 21 206 225 205 226 0.92

4 8 2.3e-07 1.4e-05 24.9 1.1 1 23 234 256 234 256 0.98

5 8 0.00053 0.033 14.3 4.1 1 23 266 288 266 288 0.96

6 8 0.00051 0.031 14.4 1.0 1 23 294 316 294 316 0.96

7 8 6.5e-09 4e-07 29.8 2.8 1 23 322 344 322 344 0.99

8 8 0.0027 0.17 12.1 5.4 1 23 350 373 350 373 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	1.2e-05	0.00072	19.5	0.9	1	23	151	173	151	173	0.99
2	8	0.96	59	4.1	1.8	1	21	177	197	177	198	0.91
3	8	0.0083	0.51	10.5	0.7	2	21	206	225	205	226	0.92
4	8	2.3e-07	1.4e-05	24.9	1.1	1	23	234	256	234	256	0.98
5	8	0.00053	0.033	14.3	4.1	1	23	266	288	266	288	0.96
6	8	0.00051	0.031	14.4	1.0	1	23	294	316	294	316	0.96
7	8	6.5e-09	4e-07	29.8	2.8	1	23	322	344	322	344	0.99
8	8	0.0027	0.17	12.1	5.4	1	23	350	373	350	373	0.92

Sequence Information

Coding Sequence: ATGGAGGACCTGTGTCGAATTTGTGGCGGTTACTCGGAAAACTTGCTGGGCATTTTCgaccagcagctggaggaatATGTTGAAGATGCCAAGCTTGCTGAGATGGTGAAGACATGTGCCGACGTGCAGTTGGATCCCGACGACGCACTGCCCCAAAAAATCTGCATTTCTTGTGTCCACGATGCACGAACTGCCTACGGATTCAAGCGGAGATGCGAGGAGAACTATAAGAAGTTCTATTTGGCGATATTAAACGGGCAGGTCATCAAAGACGAGCACAACGTGGAGGATTTCCTATTCATTGAGAACCTTGACAAAGACAGTCTGGTAGCTAAGAAGATGCTCAACAAGGAAATCAAAAAATCACCTCAAACAGCTTCCAGAACAACCAAGTCTTCCACAACTACAAGTCGAGCTGGCAGACAGTTGAGGAGTATCAAGAATCAGCCTTTCAAATGCGAGCTATGCATCAAAGAGTTTAAGCGCCAAATAAACCTCCTGAACCACATGAAGGTTCACAGCAATTCACACGTATGCCAAAACTGCGAAGAGCGTTTTCTGTTCAAGGCCGACCTGGATAACCACCTATGTTATCGCAACAGCAATTCCACCGTCGAGTGCCCGGTATGCTTGAAGGTCTTTTCAAGCACCCAGAGCCTGGACAGCCACAAATGCAAGGATATGCAGGAGCGTTCGCCCTTTCAGTGCCCCCACTGTCAGCAGGCCTTTACTCGCGAACAAAACCTCAAGGCGCACCTGTTGATCCACGCGGAATCGAAGCAGGGAAACGGACCCCACAAATGCTCATACTGCCAGACGGGATTCTTCAACAAGACGGCCCTCAAGGTGCATATCCACGCGCACATGGGCGAGCGGCCGCATGCCTGTCCGTTCTGTGCGTCCAACTTCCGTTCCAAGCAGGCCCTTAAGCTCCACATCCGCATACACACGGGCGAGAAGCCCTACCAATGCCCCCACTGCCCCAAGACTTTTTCGGACAACAATAACCTGGCGAAGCACCGACGACGCCACTCGGATGAACGGCCCTACAAGTGTTCTATCTGCCTCCAGGACTTCCGGGAGAAACATCATCTGAAGCGGCACTTTCTGGGAAAGCATCGGGATGGAGATCAAAAGCCGAAGCAAAAGTGA
Protein Sequence: MEDLCRICGGYSENLLGIFDQQLEEYVEDAKLAEMVKTCADVQLDPDDALPQKICISCVHDARTAYGFKRRCEENYKKFYLAILNGQVIKDEHNVEDFLFIENLDKDSLVAKKMLNKEIKKSPQTASRTTKSSTTTSRAGRQLRSIKNQPFKCELCIKEFKRQINLLNHMKVHSNSHVCQNCEERFLFKADLDNHLCYRNSNSTVECPVCLKVFSSTQSLDSHKCKDMQERSPFQCPHCQQAFTREQNLKAHLLIHAESKQGNGPHKCSYCQTGFFNKTALKVHIHAHMGERPHACPFCASNFRSKQALKLHIRIHTGEKPYQCPHCPKTFSDNNNLAKHRRRHSDERPYKCSICLQDFREKHHLKRHFLGKHRDGDQKPKQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00607918;
90% Identity: iTF_00539859;
80% Identity: -