Basic Information

Insect: Drosophila silvestris
Gene Symbol: -
Assembly: GCA_035043445.1
Location: JAWNMZ010000043.1:3305148-3318209[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 2.8 1.9e+02 2.8 2.3 3 23 305 327 303 327 0.92

2 14 1 68 4.2 0.7 3 21 468 486 466 490 0.92

3 14 0.23 15 6.2 0.6 2 23 512 534 511 534 0.92

4 14 0.049 3.2 8.3 0.6 1 23 551 574 551 574 0.95

5 14 1.2 77 4.0 0.2 1 21 579 599 579 603 0.90

6 14 0.0071 0.47 11.0 0.1 2 23 662 684 661 684 0.95

7 14 0.7 47 4.7 0.2 1 21 689 709 689 709 0.92

8 14 0.0064 0.42 11.1 2.1 2 23 776 796 775 796 0.96

9 14 4.1e-05 0.0027 18.0 1.0 1 23 802 825 802 825 0.97

10 14 0.00029 0.019 15.3 0.4 1 23 851 873 851 873 0.98

11 14 1 69 4.2 0.4 1 23 880 904 880 904 0.95

12 14 0.22 15 6.3 5.6 1 23 909 933 909 933 0.97

13 14 0.0019 0.13 12.7 1.8 1 23 946 968 946 968 0.98

14 14 0.0013 0.084 13.3 3.4 1 20 974 993 974 995 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	2.8	1.9e+02	2.8	2.3	3	23	305	327	303	327	0.92
2	14	1	68	4.2	0.7	3	21	468	486	466	490	0.92
3	14	0.23	15	6.2	0.6	2	23	512	534	511	534	0.92
4	14	0.049	3.2	8.3	0.6	1	23	551	574	551	574	0.95
5	14	1.2	77	4.0	0.2	1	21	579	599	579	603	0.90
6	14	0.0071	0.47	11.0	0.1	2	23	662	684	661	684	0.95
7	14	0.7	47	4.7	0.2	1	21	689	709	689	709	0.92
8	14	0.0064	0.42	11.1	2.1	2	23	776	796	775	796	0.96
9	14	4.1e-05	0.0027	18.0	1.0	1	23	802	825	802	825	0.97
10	14	0.00029	0.019	15.3	0.4	1	23	851	873	851	873	0.98
11	14	1	69	4.2	0.4	1	23	880	904	880	904	0.95
12	14	0.22	15	6.3	5.6	1	23	909	933	909	933	0.97
13	14	0.0019	0.13	12.7	1.8	1	23	946	968	946	968	0.98
14	14	0.0013	0.084	13.3	3.4	1	20	974	993	974	995	0.95

Sequence Information

Coding Sequence: ATGAACACCGAGTCGACAGATCTGGAGGACACGCATCTGTGCATCAAGTGCAATGCGACAATTGTGGGTCTGAGCAAGTATGTTGAGCACCGTAAACGGAATTGCCTCAGCACTGGCGGCGATGAGCACCTGTCGAAGCAGGTGGTGACTCCGGCAACGACGTCGGCTGCCAGCGAACAAGTCTCGCACTCAGACATGCGTCGCAGCAACTTGGACCACAGCTATGATGGCTTCCACTTTGCAGAGCCGGAGGCACCCAGCAGTTATCTGCGCAAAACGGCCTCCAGTCATGGCGGAAAGACGTCCAAGTCCCTAACGGATTCCTATGATCCGACGTACGAGCTGGGTGCCGATCTGTTCTTCTcatcgctgcagctgcaaagcGTCTCAACTGGCGGCAAGACAGGTGCACGGCCGGAGCGTGGCGCTAAGGAGGAGCAGAGCTGGCACACGTCCAGCAACTGCTCCGATCCGCTACTGAAAGCGGTCCGGGAACACGAGGAAACCCACTTTAAGTCACTCAAATTTGTGCACTCGCCCGAGGCAAGCGAGGAggaagacgacgacgaggacttcgagggcgatgatgatgagcatgaacatgaacatgaacatgatcacgatcccgatcccgatccTGAGCCTGATGAGGATTACGATGGGCGTCGCCATTCGCCGCCGACGGTGCCTGCCACGCACACTGGCGGCAAATGGAAGCCAGAGCATCGTCCGCAACTGCAACACACTCACCTGGAACGCATCTCGCCCAGCTGGGACGAGCCGCCCGAGGAACAACACGATCATCCGCCGGCGGAGCACACGCACGGCAAATGGGTGCCGGGCAGCAAGCAGCTGGAGTATCGCGAGAACATCGATCTGACCAAGTTGCAGCAGCCAGGCGCCAGCTACTGGTGCAACATCTGCTGTCGCCGCCTCAAGACGCGCCTCAACTACGAGCAGCATCTGCGCAGCGCCTACCATCAGCGGCGCGCCGACGCCGAGCGTCAACTGGAGCAGGCCAATCTCGCAAGCGCCAATCTAACGCTCACCGCCAAGGACTTCCCACAGATGCCGCCGACGGAGCAGCCGCcgcgtcgtcgccgtcgtcgtgcCCACTTTCTGCGCTGCGATCTGTGCCGGCACAGCATGGCCCGCCATCTGATGGGCAAGCATCTCATCTCGCACTACCACTATCGccgcctgcagcagcagcaaccgaaCGAGCTGCGCCGACAGAGCGCCCTGCATGACATCCTCGAGCACATGGGCAGCATTGTGAGACAGGCGCCGTTCCAGTGTCTGCCCTGTCGCTTCTATGCCAACACTGAGCAATCCTTTCAGCTGCATTGGCGCTCCGCGACGCACGTGACGCTGACGGAGCGACTTGGTGGCAGCTTCTGGTGCAGCTACTGCCAGTTCGAGTGTGCCAGCAATGAGGAGATGTGGCAACATCTGCTCGGCTCCTCGCACAAGGAGGTGCTCTTTGCGATCAATCGTTCGGTGCCCGTTTGCATTGGCCAGCGTCGTCCGCTGACCTGTTCCCGCTGCAGCGCCAGTTTCCTGTACAATGCGCAGCTGCGTCGTCACTTCGCCTCGGAGCATGTGGGACTGGTGGCAGCGGGCAGCGCTGCCGATGACTATCAGTGCCGCTTTCGCTGTGGCATTTGTGGCGTTGCACAGAGATCTCGAGTGGCGCTGCAGCGGCACGAGAAGCACCAGCATCGATTGGCCAAATACTATTGTGCCCTTTGTCGGCTGGAGTTCGAGACGCCGCTAGAGGCGCGACGCCATCGCAGCCTGATGCAGCACAAGCGGCGAGCTTGCCGAGAATTGAGCCGCAaatccaacagcagcagcagcactaatCAGCCGGATCGCGAGATTCAACACATGCTGCACGAGGtgctggaggagcagcagcctgcagcagcagcaggagaacaGCCAGCAGCCCTGAGTTCCAAGCGGCGACGCCTGGCCAGCCAGTGTGTCAGCTGTCCGCTCAGCTTTGAGACACCTCAGGCACTCGTCCAGCATCGTCGCGAGTTGCATCCAGTGGACAATCATGCCTGTCTCAGCTGTGGGAGTAGCTTTCAGTCCGCCCAGGCTCTGGGACGACACACACGCTGCTGCCAGCCCACAGCGTCCACCTCGACAGCTGTTGCTCccgctgctcctgctccagctccagctccggcTGCAACATCTGAATCAAAGTCATGGAACTGTGCGCAGTGCAGTTTCACTGCTCAATATGAATCGGATTTGCTCTATCATCGCTTCTTTCACACCCACGGCTCGGCAATTGGCAAGAATGAGCTGCTCCAGTGTCCGCTGTGCCCCAAACAGTTTCGCAAGCACTCACTGCGTCCCCATCTGCGCAATCATACGGACGAAAGGATCTTCGAGTGCGTCGAGTGCTCGGCCAAGTTTGCCCGCAGACACAATCTCAAGAATCACATCGCAACAATGCATGGCCCAAAGGAGAAACCATCACCGGCTGCTGATAAGTCAACAGTCGAGCAATCGAAAGTTGTTGCGAAGCAGAAATATCAATGTGGCACCTGTGGCAAAATACTGGCCAAAAAATACTCACTGAAACTACACGAAATGAGCCACGCTGAGGTGGAGCGTCAGCATCGTTGCCACATTGAGGATTGCCAATATGCCGGTCTCACGCCGGAGGCACTCAAAGTCCATCTAATCTCCCATGCGAATGGAAGTCACAAATGTGAACACGACAACTGCCAATATGTGGGCAAAAGTGCGCTGCACTTGAAAAGGCACCTCAAGTCGCATGTGCCCGAAAAGGAGCTGATCGAGGATGGCAAATGGTTTCCGTGCGATCAGTGCGAGTTCAGGGCCCGCATCAGGGGACATCTGAGGCGGCACATGCGTAGCCACACTGGCGAGAAACCCCATCAGTGTCCGCACTGTGACTTCCAGTGCAGCAGCATGGATAATCTGCGCAAGCACATCGTCAAAACGGGCAAGCATCCTGGCAAGTTCATCTACGAGTGTTCGTCCTGCGACATCTTCAAGAGCAACAGTTTCAAGGATCACCGACTACATTTGGCcacgcataaaaataaattgcccTAA
Protein Sequence: MNTESTDLEDTHLCIKCNATIVGLSKYVEHRKRNCLSTGGDEHLSKQVVTPATTSAASEQVSHSDMRRSNLDHSYDGFHFAEPEAPSSYLRKTASSHGGKTSKSLTDSYDPTYELGADLFFSSLQLQSVSTGGKTGARPERGAKEEQSWHTSSNCSDPLLKAVREHEETHFKSLKFVHSPEASEEEDDDEDFEGDDDEHEHEHEHDHDPDPDPEPDEDYDGRRHSPPTVPATHTGGKWKPEHRPQLQHTHLERISPSWDEPPEEQHDHPPAEHTHGKWVPGSKQLEYRENIDLTKLQQPGASYWCNICCRRLKTRLNYEQHLRSAYHQRRADAERQLEQANLASANLTLTAKDFPQMPPTEQPPRRRRRRAHFLRCDLCRHSMARHLMGKHLISHYHYRRLQQQQPNELRRQSALHDILEHMGSIVRQAPFQCLPCRFYANTEQSFQLHWRSATHVTLTERLGGSFWCSYCQFECASNEEMWQHLLGSSHKEVLFAINRSVPVCIGQRRPLTCSRCSASFLYNAQLRRHFASEHVGLVAAGSAADDYQCRFRCGICGVAQRSRVALQRHEKHQHRLAKYYCALCRLEFETPLEARRHRSLMQHKRRACRELSRKSNSSSSTNQPDREIQHMLHEVLEEQQPAAAAGEQPAALSSKRRRLASQCVSCPLSFETPQALVQHRRELHPVDNHACLSCGSSFQSAQALGRHTRCCQPTASTSTAVAPAAPAPAPAPAATSESKSWNCAQCSFTAQYESDLLYHRFFHTHGSAIGKNELLQCPLCPKQFRKHSLRPHLRNHTDERIFECVECSAKFARRHNLKNHIATMHGPKEKPSPAADKSTVEQSKVVAKQKYQCGTCGKILAKKYSLKLHEMSHAEVERQHRCHIEDCQYAGLTPEALKVHLISHANGSHKCEHDNCQYVGKSALHLKRHLKSHVPEKELIEDGKWFPCDQCEFRARIRGHLRRHMRSHTGEKPHQCPHCDFQCSSMDNLRKHIVKTGKHPGKFIYECSSCDIFKSNSFKDHRLHLATHKNKLP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00528388;
90% Identity: iTF_00482583;
80% Identity: -