Basic Information

Insect: Drosophila silvestris
Gene Symbol: ken1
Assembly: GCA_035043445.1
Location: JAWNMZ010000137.1:500-2806[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.14 9.4 6.9 6.3 3 23 231 251 229 251 0.96

2 11 0.0015 0.098 13.1 1.2 1 23 257 282 257 282 0.92

3 11 0.0019 0.13 12.8 1.5 1 23 289 314 289 314 0.93

4 11 0.00025 0.016 15.6 4.1 1 23 324 346 324 346 0.97

5 11 0.00018 0.012 16.0 1.8 2 23 354 375 353 375 0.96

6 11 7.1 4.7e+02 1.5 0.6 1 7 381 387 381 389 0.88

7 11 0.026 1.7 9.2 1.9 1 23 392 415 392 415 0.97

8 11 0.017 1.1 9.8 4.1 1 23 421 443 421 443 0.95

9 11 0.0084 0.55 10.7 2.3 2 23 450 471 449 471 0.96

10 11 0.00016 0.01 16.2 0.8 1 23 556 579 556 579 0.96

11 11 0.0087 0.57 10.7 3.1 1 23 585 607 585 607 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.14	9.4	6.9	6.3	3	23	231	251	229	251	0.96
2	11	0.0015	0.098	13.1	1.2	1	23	257	282	257	282	0.92
3	11	0.0019	0.13	12.8	1.5	1	23	289	314	289	314	0.93
4	11	0.00025	0.016	15.6	4.1	1	23	324	346	324	346	0.97
5	11	0.00018	0.012	16.0	1.8	2	23	354	375	353	375	0.96
6	11	7.1	4.7e+02	1.5	0.6	1	7	381	387	381	389	0.88
7	11	0.026	1.7	9.2	1.9	1	23	392	415	392	415	0.97
8	11	0.017	1.1	9.8	4.1	1	23	421	443	421	443	0.95
9	11	0.0084	0.55	10.7	2.3	2	23	450	471	449	471	0.96
10	11	0.00016	0.01	16.2	0.8	1	23	556	579	556	579	0.96
11	11	0.0087	0.57	10.7	3.1	1	23	585	607	585	607	0.95

Sequence Information

Coding Sequence: ATGAATGAGGGTAGGCAAGCCTCCATACACGCAATATGCCGCACTTGCTTGTCAAAAGTGCAGCATTTTGGAGCATACGATTTGTTTGTGGTTCCAGGACTTGCCAAGAAACTGTGTGTCTGCACTTCACTCTCCGTGCAGCAGCATGATGGCTTCCCAAGGAACCTTTGCTCCAGTTGCTACACCCGGCTAAACGACTTACATGATTTCCAGCAGAGATGCATGGACTCTGTACAAAAGCTGAAGGATTTGCTAGCTAGCAATTACTTTAGAATCCACAATGGCGAAGTTGACAATTTTGATGTGCTAAGTGTGGTGGCGCCACAGAATGCTGATGTGCCTGTCGAGGAAGATGATAATATCAACTTTGATCCGCTACTTAAtaccaaaattgaaataattgagAATGAGGAGgatgtatttaaaatgctagAAGATGTCGACAAAGAAACGGAGCAGGTAGACATGGAAAAGGAGTCCTCCAGTGGCAGCGAAAACGGCAATTATGATACAGAAGCAAATAACAGCGACTCCGACGACACCTTACCTCTATCCAGATTACGCAGTACTACAACAGAAGCTAAAGcaaatgacgatgatgatgatgttaaGGCCGACGATATAACCACGGTTAAATCAAAAAGCAAGCGGATTCCGGCCGCCGAACGTGAGCTGCGTCGTCTAATTGATTGTCACATTTGCCACCAGAAGTTCAAGAAAGAAATTCGCTACGAGGAGCACATGAAGCATCACAATGACTTATTGCCATTCCAGTGTACTGTGGAAACCTGCAGGAAGGGTTTCACAACTGCCGCAGCTCTGCGACATCACGTGGATCATGCCCATTCGGAACTCTGCGAACTGCACGCCTGCACCGTGGAAGGATGTGACCAAGCATTCCCCCGCACTCGAATGCTCACACATCACCTGAAAAAGATCCACAAAATTGCCAAGCCTGAGATTCGTGATCATCCGTGCACTGAATGTGACAAAGTGTTCCGTTGCCCAACAGCTCTGAAGAAACACATGTATAAGCACACTGGCGAGGAACTGCCGATTTCCTGTAACATCTGCAACAAGCGCTTCCACATAAACAGCGATCTCAGAGATCATCTCTTGCGCCATGCAGGTGTAAAGAATCATGTGTGCCCATACTGCGGCGTCGGAAAACAGTTCCAGTGTCGTCAGTGCGATCATGCTTCCCACAACAAGCAAGCTCTGGCCAATCACGTTAAGGTGGTGCACATGAAGATCAAGAACTTTGCGTGCCAGTATTGCGGCAAGACCTTTGGCAAATCGCATGCGTGCAAGATCCATGAGAGACTTCACACGGGCGAAAACTGCTGCGAGTGCAAGATCTGTGGCAAGATCTTCCTTTTCGAGAAGAGATTAACCAAGCATTTGCAGATCCACGAGAAACGTGATATACCGTCTCCTGCAACCAATATTAAGCCACAGGACGACGAGAGTCCGCCAAATGTGGGCCAGCAGTCAACTGAGCTAAAGGATACGAAGCCCATGACAGCAGTCCCCAAGCCAAAGAATTCGCATCGAGTTGAACGTGTTGATATATCGCAGCTAGCAGGCACTTCTGTAAATCCAATATCATCAGTATCGGTGCCCTCGTGGTCGCCGCAAGTGAATTTCACAAAGAAGGAAGGCCAGCACATTTGTCCCGGCTGTGGACGTGGCTTCAATCACATTGGCAATATGAAACTGCACTATAAGGTGATACACGAAAAGATCAAGGATTTCGCGTGTCGCTTCTGCCCCAAGCGCTTTGGCAAGGCTCAGTATCTTCGACATCATGAATACACGCATACTGGCGAGAGGCCGTACGGCTGCCCCAAAGGAACTAAAGGTGCCGCCCAAGACAAAGGCGGAACAGCAGAGGCTAAAATTGAGCTGAACAAGCGTCCGCCAAGAAACTATGAACAGTACCAGGATCCAGCAGCAGAACGGGCTGCAGCCACCGCCGAGTTGCTTGCCAAGCAGCTCGAAGAGAGTGAATCCAAACGAAAAGCTGAGGCCAAGGCTCGGACTATTCAAGAGGCCGCCTGCGAGCAGCTTCAGAAACTGCAGAAGGAGCAGCTGATCGAAAAGATATCCTGTGATAGCTTTCAAGTACAAAGGTCTGAGACCGGCATAAGCGTGGATGCACTCAAAGCTgataatatataa
Protein Sequence: MNEGRQASIHAICRTCLSKVQHFGAYDLFVVPGLAKKLCVCTSLSVQQHDGFPRNLCSSCYTRLNDLHDFQQRCMDSVQKLKDLLASNYFRIHNGEVDNFDVLSVVAPQNADVPVEEDDNINFDPLLNTKIEIIENEEDVFKMLEDVDKETEQVDMEKESSSGSENGNYDTEANNSDSDDTLPLSRLRSTTTEAKANDDDDDVKADDITTVKSKSKRIPAAERELRRLIDCHICHQKFKKEIRYEEHMKHHNDLLPFQCTVETCRKGFTTAAALRHHVDHAHSELCELHACTVEGCDQAFPRTRMLTHHLKKIHKIAKPEIRDHPCTECDKVFRCPTALKKHMYKHTGEELPISCNICNKRFHINSDLRDHLLRHAGVKNHVCPYCGVGKQFQCRQCDHASHNKQALANHVKVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLQIHEKRDIPSPATNIKPQDDESPPNVGQQSTELKDTKPMTAVPKPKNSHRVERVDISQLAGTSVNPISSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKVIHEKIKDFACRFCPKRFGKAQYLRHHEYTHTGERPYGCPKGTKGAAQDKGGTAEAKIELNKRPPRNYEQYQDPAAERAAATAELLAKQLEESESKRKAEAKARTIQEAACEQLQKLQKEQLIEKISCDSFQVQRSETGISVDALKADNI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00499101;
90% Identity: iTF_00542659;
80% Identity: -