Basic Information

Insect: Drosophila silvestris
Gene Symbol: HIVEP2
Assembly: GCA_035043445.1
Location: JAWNMZ010000166.1:4363846-4372646[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0015 0.1 13.1 0.4 2 23 278 299 278 299 0.98

2 8 0.00024 0.016 15.6 3.2 1 21 305 325 305 329 0.90

3 8 0.0086 0.57 10.7 0.5 1 19 976 994 976 997 0.93

4 8 2.9e-06 0.00019 21.6 2.0 1 23 1743 1765 1743 1765 0.99

5 8 1.2e-05 0.0008 19.7 5.3 1 23 1771 1795 1771 1795 0.92

6 8 0.00055 0.036 14.5 3.5 2 23 2285 2306 2285 2306 0.97

7 8 0.00083 0.055 13.9 1.2 1 23 2312 2336 2312 2336 0.91

8 8 0.0027 0.18 12.3 2.7 1 23 2357 2381 2357 2381 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0015	0.1	13.1	0.4	2	23	278	299	278	299	0.98
2	8	0.00024	0.016	15.6	3.2	1	21	305	325	305	329	0.90
3	8	0.0086	0.57	10.7	0.5	1	19	976	994	976	997	0.93
4	8	2.9e-06	0.00019	21.6	2.0	1	23	1743	1765	1743	1765	0.99
5	8	1.2e-05	0.0008	19.7	5.3	1	23	1771	1795	1771	1795	0.92
6	8	0.00055	0.036	14.5	3.5	2	23	2285	2306	2285	2306	0.97
7	8	0.00083	0.055	13.9	1.2	1	23	2312	2336	2312	2336	0.91
8	8	0.0027	0.18	12.3	2.7	1	23	2357	2381	2357	2381	0.92

Sequence Information

Coding Sequence: ATGACGCTACAGCAGGTGGCAAGCAGCGCAGCGAGCAATGtggcaggaacaacaacaacaacagcaacaacaataccagccACAGccaacaccaccagcaacaataacaacaatcagaacaacaacagcaacaacaacaacaacaacagcagcagcaacaaccacaacaacaacaacagcagcagcgaggatccaacaacagcgacagcaacaattgtCGATGGCTGGACGAGCTCAACCAATTTGCGttatttgcacaaaaagtTTAAACGGCTGGCGAGCACCACCGAACCAGAGTCGGTGAATGCAATGGCAGCGGTGCGCACCACATCGCTGTCATCGAATAGCTCGTTGTCGCCACCGCTGCCAGTGGTCGCCGCACCACTGCTCAATGGACATGTGACGGTGAAGGTTGCTCCCTTGCTGCCGGCAAGAAATTTAGAATTCAGTGCCAATTTCGTAAATGCcaacgacaacatcaacatcagcaacaacaacaacaacaataacaataacaacagtcATGAGGAGAGCAACAAGCATGGCaatgttggtgttgctggtgcgCCTCGAACACGCACGCCCCTCAGCAACagtaatagcaacagcaatattaACTATGCCAGCAATGCAACACTGTCGCCAGCAACATTcgcacagcatcagcaacaaacgcagccaacgccagcagcaacagcagccgcaataacaacaacaacagcaacagcaccagcagcagcagcaataacaacaacaacaacaacaacaataatacaaacagcaccagcaacagttgcagttgcaggatTGGGCGAGAAAACTAGTCGCCCCAAGTGCCCCTATTGCAATCTGATCTGTGCAAAGCCATCGGTGCTGGAGAAGCACATTCGTGCCCATACCAATGAGCGACCGTATCCGTGCAACAACTGTGGCATCGCCTTCAAAACGAAGAGCAACCTGTACAAACACTGCCGTTCCCGTTCCCATATGGCGCGCATGCGTGGCCTCGATGTGCCAGCCAATGAGACGGACGGTCTGTCCGACCAGGATGGCGACGGAGAgctgagcaacagcagctccgAGCTACTAAGCGTCGAAGTTTTGAGTCGCACTGATTCGCCTTATGATGAGGCAATGGCCTCGCCGACGCCATCACCATCGACGCTGTCGGCGGCGAAGAGTACGTatctgcagcagccgcaactgcaacagcatatgctgcaacagttgccgctgGGCTCACCAGCAGCCGGAACACTGCCGCCCGCCCCGCCCGCTGACTGGCTGCACTCGGCGACCGCTCAGCATCGCCAGTCGCTCGACTACAAGCCATACAAGCCCAAGTTTCACAATGCATCCCTCTATGCGCCCGGCACCCtcaaggagcaacagcaacagcagcagcagcagcagcaggtactgcaacagcaacagcagcaggcgttgctgcaaccacaacagcagcaacacaaactgtcagcgcagcaacagcaacagcagcagcagcagcaacaacaacaatcgctgGCGCATCCAACGATCTCGCCCAGCACCCAGTTGAAGCTCAACAATCACATCAATTCGcatcagttgcagctgcagctgcagcaccagcaccaacaccagcaacagcagcagcatttgcacGCACAGCAAtccttgctgctggctgctgcagcaaccaATCCGGTTGCATTGTCTGcattgccaccgccgccgccgggCGTTTATTATTTGGGACAGCCGCAGTATTATAatccaactgcagctgcaatgcATCAGCATGCGCTGGCCATTCAGcagatgcagttgcagcagcactttcagctgcaacaacagcagcagcaacagcagcatcaaaatcaccaacagcagcagcagcagcagcaacagcaacagcagcagcagcagcagcatcaccaacagcagcagcagcagcagcagcaacactcgCCATTGCTGAAggcgccacagcagcaacagcagcagCAGCTGTTGCGCTCCACTAGccaacagcaggcagcagtgattgcaacaacagcagcgctgccagcaCCAGCCACACCCAACCCGCCAACCAATCTGAGCAGCTTTGCCAGCTCAAGCGGCGGCATGCAAGTGAATGTGGAAAAGGTGCAGGAGCACATCTCCAAGCTGATCTCACAGAACGAGGCGATTGTGGAGAACAAGGAGATTCTGCTGCAGAAGAAGTATCCCAAGCAGCTGAATCGTTCGCGCAGCttcaacaatgccaacaacaacaacaacaatagcagcaacagcaacatcaccagcagcagcagtataccaacaacagcgcatgccaacagcaacagtaacaacaacagcaatcagcaGCTGGGCGAGACGAAAGTGAACCTGGCACAGGCCATAgtacaaaaacagcagcagcagcaacagcaacagcagcatatgcaacaacagttgcagcagcaacaataccaattatacttgcaacagcaacagcaacaacaactggagcCGCCTGTGAATGGTCTGCtcaaacgcagcagcagcagctctgcAAGCAGTACAGCCAGCAGCGGCTATGCCAGCTTAAGAatgcaacagttgccgccgccgccatcgccgttgccgttgcaacagttgcagtatCGCCAGGATCCGTCAACGCCAGTGCCcaagctggagcagcagcagcagcagttgcagcaacccTTGCCACTGAATTTGTCTGCCAAGCCCAAGCCGGCGCTAGCAATGCCAGCAAAAccaacgccaacagcaacagcagccgcagccgcaccagcaacaacaattgttgttgccaagagcacaacaataacagcgccAGCGGCAGCACCGAATATCTCCATAATCAAGAATCTGCTGTTGAATGCACGTGGCCTGGCAGTGCCAATTGGCGAGGGCGACGATGCCGTCTACTCCTGCCCCATTTGCGTCAGTAAGTTTCGCAGCGCGGACGAGCTGAAGCACCACAACAGCACCTACTGCCAGGATGCGAACAGCAGTGCACCGATCAGTCCAGCCTCATCGCCGAGCAGCAAATACTTTCGCTCCAATTCCATATCGTTTAGCCTGCCAGAGCTCCAGTCGCACATGGCCAACTCGAAGAATCCGTTGTCGCTGGCCAAGCTCGCCAAGGTTGCCTGGTCGCAGCTAAAAACCAAGCCGAGCAGCCTGGTTCTCAGCCGTCTCAGTGCGGCACAATCTCCCGCACGCACCTCAACCGTCACAGCAgctatcaacagcagcagcagcagcaacaacagcaaccacataaacagtagcagcagcagcgccaatcacaacagcaatcacagcagcaatcacataccagcaacggcagcaacagctgttgtaATCCCGCCCAGCATTGATGCCACCAGCGTTGCCTTGCGTTTTGTGGACGCACCGCTGCCATCGCCGGGTCCGCTGCTCGGCAAGACACCGCTGGTGGATTATGCGGCGCCACGCAAAGCGCCCGATGCCCAGGTGGTCATCACGAAAATGCACGAGGATCGTCTGGAGAACATCATCGTTGAGGCGCCATCGAAACGGCTCAAGCTGAGCAGTGGCGAGACATCGTTCACGCTGCCATCTGTCGTCGATATGCTCTTTGCTGGCAATCCAGAGTTACAGTTCAGAACCAAGGAGGAGCGTTTGCGTCGCTTTACCTCATCCGGCGGCACCATGATACCCATTTCGGAGTGTCCCGAGCTGGACAAGAGTCCCAAAATGATACGCACTCCTCTGTTGTCCGGCGGCAGTTTCCAGGAGATGTCGCCGCGTCTCAGCGACATCAAGGAGCGCAAACTACtcgctgccaacaacaacaacaacaataacaacaacaataataataataataatggtttCCTGCTCAGCGCCTCCAACACGCCGCATCATTTCCAATTCCCACCCATCAATTCGATAACCGCCTTCAATCCGCTCACCCTGCCACCgatgtgcaacagcagcggcaccagcagcagcagcaacattgtgGATAAACCGATACCCTATGTGCAGGGCATACCTGGTCCGGGCAGCTTATCgttgctgccaccgccaccgccactgcagctgcagcgtgGACGCAGCCCCAATCGCAAACAGCCCAGTCCCAATACGAATGCCAATCTCAATATAAATCTCAATCCGCTGCTGGCAGCCGAGGGCCCACTCAAGGCACTCTCGCCCTTCGGTGGCGTACAGAATTTGCCCAGCGAATTCAGTCGCCAACCACCAACGCCAGCGCAACGCAATGCGCTCCAATggacgaacagcagcagcagcagcagcaacaataagctGCCAGTGATTGTCGCTGACGGCACGTTGGCCAAGAAGCCACCATTCAATTTTCTACGCATGGCGGACAATGTGAAGAGCTCCGCTGAGGTGCGTCACTTTAATTTCGATAATGTGAACAAATCGCAGGAGGTGCTGGCACCGCTGCACGTCGACACGCCCgatgaggcagcagcagcagcagcaacagcagcagcaatcaaaacaacaacaaccactgcAATTCTAGTAGCTGCAACAACCGCAACGAGCATTGCCAAGTCGAAATTCTTGCGACCCACCAGTCTGCCCCTGAAGCCGGGCACCTTTACGCCAAAGCGACATCATGGGATCACACCGACTGCCAATACACTGCCCCTCATCTCACCGGAAACACCGAGACCCTCCAAGTCGTGCGTGCAACTCTATCTGAATGGGCATGCGTACACCTATCTGGGACTCAAGTGCAGCACCAAGATGTTCTACTGTACGGTGAACTGTCCGCAGCCCTCGTATGTGGCGGGCATGCACAAGCTGTCCATGTACAGTGTGTGGCAGGTGTGCGAGGAGAATCAGCCGCATCCGCTCGGTTTCAAGCCCCGACAGGTGATGGCCTTGTACGATTCCAGGCAAAAGATGCTCGGCACTGGCTGCACCACAGCAATGGCGGGTGCTGGCAAACTGCAGTACTCCGTCTTCAGTTCACAGGAAACGGTTAGCACGTGCTCCACCACGGCCAACGGGCAGAGCAAGTTCTACCAGCACCAGTTGAAACAGCCGCCGTCAATTGGCGCACTCAGCGAGGCAAATGTGGCAGCCAAGGCCAGCGAAGAGGCGGCTGCCAAGAAGCTGGAAACGGGTCAACTATTGGTCGGTGGCTACGAGTCGCATGAGGATTACACGTACATTCGTGGACGCGGTCGTGGTCGCTACGTCTGCTCCGAGTGTGGCATACGCTGCAAGAAGCCATCCATGCTCAAGAAGCATATACGCACCCACACCGATGTGCGTCCATTTACCTGCAGTCACTGCAATTTCAGCTTCAAGACCAAGGGCAATCTCACCAAGCACATGCAGTCAAAGACGCACTTCAAGAAGTGCATCGAGCTGGGCATCAATCCGGGCCCGATGCCCGCCGACGGCGAATTCCTTGATGTCGATGACTTTGATCAGCAATCGTCGACATCGGCGGGCGGACGCACCTCCTCCATGGCCGGTGAATCCGATTCGGATGACTACAGCGACAACGAGTCCGAGAGCAGTGACACCGATGAGTCCAAGTCGCGCATGAAGGAGCATGAGGCGGCACGGGgtctgctgtcgctgtcgatGACGCCGCCGATACCGCAGAGTGTTTCACCTTATCCGGCACTGGTCCAGGATACGCCGGCTGCCAGTCCAGCGAACAGCATTGGCTCCTCGGCTGGCAGTGCAGCTGGCAGCGGTTCGCAGCCGAAGCGACAGGTTTGCTCGTTTACGTCGCCAAAGCCGCCGTTTGACTACCAGAAGCAGGAACAGTATTACTCCAATCCCGAGGAGTCCAAACCCAAGCGCGGTGTGCCCAACGATGAGAGCAGCGCGCCCATGGATCTGACCAAGCCACGTCCAATGCCCAGCATTTCAGTGGCGTCCTCTTCGCCCGTCGCCGACCAGATGCAGGCGCAGACACCCAAATCGCAGGCACAGCAGATGCGCGACGTAATCTTTGGCGCCGGCAACAACGAATGCGGCTTCATGAAGACCCTAATCTCTGTCTCCGACAAGGTGCGCATCTCTGCCGAAATTGAGGAGCAGGCAAAGCGCGAAAGCGAGGGCGAAGATGTCCTCCTGCAGACGTACATCAAGGAGCAGGCGCTGCAGCATGCCAAAATGAAGCAGAGCCAATTTAGTCGCAGCTACCTGGTCACTTCCACCACCAGCTCGAACTCCAactgcatcagcagctgcagctccaaCTCTACCACGACCAGTGTTAGCGTTAGCTGTGTTGTGACCACGCCCATTGTTAATAGCAAGCCACAGTTGAACATCGCGGAGCTGCCCAGCATTGAGGTGCACGAGGTGAAGACACCAGAGTCGCCAACGCCATCGTCGGCACTTGTCAAATCCGCCGAGGAGAGCGAGGAAAGCGAAACGCAATCGGACCAGGAGAAGCCCAGCATAGCAGCAACGTCCATTCCTGTGCCAGTAACCGTCCCTGTTTCAGTTGCTGTACCCGTTTCCAGCTCCAAGTCGAGTGCAGAGATTCAGCAGCCGCACAATGCCAATTTGCCagctgcagtgcagcagccAGATGCCACCGATTTTAGTGGCgtactcagcagcagcagcagcaacaaaaataacaacagcagcagcggcagcagcagtggatCAACTGCACCCACACGTATTGTGGTCGTCGGTGAGGATGGCTTCAAAACGACACCAACCAGCGGCAGCAACGAGTTGCAGTCTGGTggcgcaacaacagctgcaacagcagccgcaacagcaggtGCAACGTATACGAATCGTTTGGTGCCACCGCCGCCAATAGCGAGTGATGCGCGACCCACTTGCACCGTTTGCAACAAGACGTTCCAGCGAACGCATCAGCTGTCGCTGCACATGAACATCCACTACATGGAACGGAAGTTCAAGTGCGAGCCGTGCAGCATCTCGTTCCGCACCCAGGGTCATCTGCAGAAGCACGAGAGGAGCGAGGCGCACCGCAACAAAGTGATGATGACATCAACGTTTGGTGTGCCAACCACATCCAATCCGCGTCCCTTCGAGTGCACCGATTGCAAGATTGCGTTTCGCATCCACGGCCATCTGGCCAAGCATCTGCGCTCCAAGACACACGTGCAGAAGTTGGAGTGCCTGCAGAAGTTGCCATTTGGCACCTATGCCGAGATCGAACGGGCTGGCATCAGTCTGACGGAGATCGATACCAGCGACTGTGAGAATTCGCTCATCTCGCTCAAGCTGCTGGCGCAGAAGCTGCTCGAGAAGGATCCGAACAAGCTGAGTGGCTACACAACGCCGTCGGGCATGCTGCAGCTATCGGCGGATGCACCTGCTGCCGGCCAGGACAGCGCCTCCGAGGATGGCTTCAGTGCGGCGAACAGTGCCGCCGCCTCGGCCATTGCCTCGCTGGACAACGACAGTGCGGGCAACACACCGAAGCGTGCCAGCTCCATGTCCGAGGACGAGACGCTGACCAATGGACTCGGCctcagtcacagtcacagccatGGCCACAGTCTGAAGCGACGTCTGCAGAACAGCAGCTTCAGCAGCAATGGCGACGAGAGCGACAATCCAACGGATACcactggcagtggcagtggcagcagcgagAAGCGTGCCAGAagcaatacaaatgaaatcatCACACTGCCGACGCCGGTGGCTGTGTCGACGGCAACGGCCAGCAACTGa
Protein Sequence: MTLQQVASSAASNVAGTTTTTATTIPATANTTSNNNNNQNNNSNNNNNNSSSNNHNNNNSSSEDPTTATATIVDGWTSSTNLRYLHKKFKRLASTTEPESVNAMAAVRTTSLSSNSSLSPPLPVVAAPLLNGHVTVKVAPLLPARNLEFSANFVNANDNINISNNNNNNNNNNSHEESNKHGNVGVAGAPRTRTPLSNSNSNSNINYASNATLSPATFAQHQQQTQPTPAATAAAITTTTATAPAAAAITTTTTTTIIQTAPATVAVAGLGEKTSRPKCPYCNLICAKPSVLEKHIRAHTNERPYPCNNCGIAFKTKSNLYKHCRSRSHMARMRGLDVPANETDGLSDQDGDGELSNSSSELLSVEVLSRTDSPYDEAMASPTPSPSTLSAAKSTYLQQPQLQQHMLQQLPLGSPAAGTLPPAPPADWLHSATAQHRQSLDYKPYKPKFHNASLYAPGTLKEQQQQQQQQQQVLQQQQQQALLQPQQQQHKLSAQQQQQQQQQQQQQSLAHPTISPSTQLKLNNHINSHQLQLQLQHQHQHQQQQQHLHAQQSLLLAAAATNPVALSALPPPPPGVYYLGQPQYYNPTAAAMHQHALAIQQMQLQQHFQLQQQQQQQQHQNHQQQQQQQQQQQQQQQQHHQQQQQQQQQHSPLLKAPQQQQQQQLLRSTSQQQAAVIATTAALPAPATPNPPTNLSSFASSSGGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANNNNNNSSNSNITSSSSIPTTAHANSNSNNNSNQQLGETKVNLAQAIVQKQQQQQQQQQHMQQQLQQQQYQLYLQQQQQQQLEPPVNGLLKRSSSSSASSTASSGYASLRMQQLPPPPSPLPLQQLQYRQDPSTPVPKLEQQQQQLQQPLPLNLSAKPKPALAMPAKPTPTATAAAAAPATTIVVAKSTTITAPAAAPNISIIKNLLLNARGLAVPIGEGDDAVYSCPICVSKFRSADELKHHNSTYCQDANSSAPISPASSPSSKYFRSNSISFSLPELQSHMANSKNPLSLAKLAKVAWSQLKTKPSSLVLSRLSAAQSPARTSTVTAAINSSSSSNNSNHINSSSSSANHNSNHSSNHIPATAATAVVIPPSIDATSVALRFVDAPLPSPGPLLGKTPLVDYAAPRKAPDAQVVITKMHEDRLENIIVEAPSKRLKLSSGETSFTLPSVVDMLFAGNPELQFRTKEERLRRFTSSGGTMIPISECPELDKSPKMIRTPLLSGGSFQEMSPRLSDIKERKLLAANNNNNNNNNNNNNNNGFLLSASNTPHHFQFPPINSITAFNPLTLPPMCNSSGTSSSSNIVDKPIPYVQGIPGPGSLSLLPPPPPLQLQRGRSPNRKQPSPNTNANLNINLNPLLAAEGPLKALSPFGGVQNLPSEFSRQPPTPAQRNALQWTNSSSSSSNNKLPVIVADGTLAKKPPFNFLRMADNVKSSAEVRHFNFDNVNKSQEVLAPLHVDTPDEAAAAAATAAAIKTTTTTAILVAATTATSIAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKPRQVMALYDSRQKMLGTGCTTAMAGAGKLQYSVFSSQETVSTCSTTANGQSKFYQHQLKQPPSIGALSEANVAAKASEEAAAKKLETGQLLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRMKEHEAARGLLSLSMTPPIPQSVSPYPALVQDTPAASPANSIGSSAGSAAGSGSQPKRQVCSFTSPKPPFDYQKQEQYYSNPEESKPKRGVPNDESSAPMDLTKPRPMPSISVASSSPVADQMQAQTPKSQAQQMRDVIFGAGNNECGFMKTLISVSDKVRISAEIEEQAKRESEGEDVLLQTYIKEQALQHAKMKQSQFSRSYLVTSTTSSNSNCISSCSSNSTTTSVSVSCVVTTPIVNSKPQLNIAELPSIEVHEVKTPESPTPSSALVKSAEESEESETQSDQEKPSIAATSIPVPVTVPVSVAVPVSSSKSSAEIQQPHNANLPAAVQQPDATDFSGVLSSSSSNKNNNSSSGSSSGSTAPTRIVVVGEDGFKTTPTSGSNELQSGGATTAATAAATAGATYTNRLVPPPPIASDARPTCTVCNKTFQRTHQLSLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHRNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMLQLSADAPAAGQDSASEDGFSAANSAAASAIASLDNDSAGNTPKRASSMSEDETLTNGLGLSHSHSHGHSLKRRLQNSSFSSNGDESDNPTDTTGSGSGSSEKRARSNTNEIITLPTPVAVSTATASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00513682;
90% Identity: iTF_00499804;
80% Identity: -