Basic Information

Insect: Drosophila silvestris
Gene Symbol: -
Assembly: GCA_035043445.1
Location: JAWNMZ010000140.1:9514506-9517308[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 1.8e-05 0.0012 19.1 0.9 1 23 274 297 274 297 0.97

2 8 7.5e-06 0.00049 20.3 3.8 2 23 309 330 308 330 0.95

3 8 0.00026 0.017 15.5 0.5 1 23 339 362 339 362 0.94

4 8 0.12 7.9 7.1 0.1 3 23 372 392 370 392 0.96

5 8 0.00016 0.011 16.2 6.9 1 23 398 420 398 420 0.98

6 8 0.00022 0.014 15.7 0.1 1 23 425 447 425 447 0.98

7 8 2e-06 0.00013 22.2 1.7 1 23 453 475 453 475 0.97

8 8 0.022 1.5 9.4 4.7 1 23 481 504 481 504 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	1.8e-05	0.0012	19.1	0.9	1	23	274	297	274	297	0.97
2	8	7.5e-06	0.00049	20.3	3.8	2	23	309	330	308	330	0.95
3	8	0.00026	0.017	15.5	0.5	1	23	339	362	339	362	0.94
4	8	0.12	7.9	7.1	0.1	3	23	372	392	370	392	0.96
5	8	0.00016	0.011	16.2	6.9	1	23	398	420	398	420	0.98
6	8	0.00022	0.014	15.7	0.1	1	23	425	447	425	447	0.98
7	8	2e-06	0.00013	22.2	1.7	1	23	453	475	453	475	0.97
8	8	0.022	1.5	9.4	4.7	1	23	481	504	481	504	0.97

Sequence Information

Coding Sequence: atgctgCTGCACTCACATAATTTCCCACAAACTGCAATGGCTGCGCCAATAGAGATTGAGAACGAGATTGAATGCGCCAGCGATTGGCATCTTTGGTGTCGCCTCTGCGCCAAGGATGATCTTCAGGGCAACATCAATGTGTTCCTGAAAAACGAACAGTCAGCGCCAGGCGGCGATCGGGATGGCGATGCCCAGGAAGTTGCAGCAAGTGCACCAATTGCCGACATGGCTCTGGCCACAGCCATTGGCAAATATTTCTGGGTGAATATAACACGCGGCGAGGAGCTGCCCGAGATGATATGCAGCGAATGCCTGACACTCGTCACCTCGCTGGTGAACTTCTCGGAGCGCATAACGCGTGTGCAGAAACTCTATTGCATATTGCAAAGCACACCCAAGCACGATACGATTAGCGTGCAGGAGTTGCGCGGCAGATTTGGGCTGAtcgaggaggagcagcagctgccagagCAGCCAGTGCCCGAGACGCTTACTGAGGTGCATTATGTGGAGGAGAAGCCCAAGCTGAATGAATTGGACGTAACGGTGTTGGAGCTGGAAAATCCGCTCACGCCGGCAGGCAAAATCGAAGAGAAGCCTACAACTGAAGCGGTGACACCTGAAGCAGAGGAACAACAAGAGCTGGAAGATGAGGAGGTGGAGGAagcagtagcagaagcagcagatgAGCAGCTGGAATACGAAGATGCAGGcactgagctgctgctgaatcTATGCGATGCATACAGCAACGAAGACAGCAATGGGGACAGCAACTCCTCCAGCACGAAGCCCAAATCCAAGGAGCGCGGCAAAGCGCATCAGTGCAACGAGTGTCCACGTGCCTATGCTCTGCCCCAGACGCTGCAGCGGCACATGCGTCAGTACCATGACAAGAAGAGCACAGCGGACATGAAACTGCTGTGCTGCGAGGAGTGCGAGAAACAGTTTCGCTCCCGCTACCAGCTGCAGCGGCACATGCAACAGCATCTGCCCATGCCCAAGCGGAAGATGTATCCCTGCACCAGTTGCGGCAAGAAGTTCACAACCAATGCCTCAGCGCAGTCGCATGCCCAGTATATGCACCAGGAGGAGCGACCGCGTCCGGTCATCTGTGAGCAGTGCGGCGTCGGGGTGCATTCGCTGAATGCGCTCAAGGAGCACCTGCTGAGCCACACGGATTATGCGCCGTACGAGTGCGATGTGTGCAAGAAGTGCTTCAAGAGCTTGAGCCGTCTCAAGCATCACAAGGAGACGCACGATCCGCACAAGTACATCTGTCCCGAGTGCGGCATGCAACTGAATTCGCGACCCACTCTGAATCGCCATCGGCTGGTGCACACGGATCAGATGCAGCACAAGTGCGACTATTGCGGCAGGGAATTCAAGCGGGCGAAAGCCCTCAAGAATCATCTCATCCTGCACACCGGACTGAAGCCGTACTCCTGTGACTTTTGTGATCGCACCTTCGCCAACGGCTCCAATTGTCGCACGCACAAAAAGAAATCGCATCCCGAGGAGCTAGCCGCCCAGGAAGCAGCCGGTGGCGCCAAGACCTACAATCGCAATATACCCAAACTGGAGGCCCTGAAAGCATTCACAAAGAACAAGGACAACTTGTCGCCGGTGGCCACCAAGCAGAGTGGATGCTTTGCCTTTGGCAAGAAGCCCAAAGCGCTAATCAAATCCGATGCCAGCAACTCGTTGCAATCGTCGTCGGTGcccagcgcagcagcagcagttggcatTATTCCCACCATCGACAACATCTACAATCACATTATGAAGCCGCCGTtggcaacacagcagcagcagctgcttgtcACCAATGGCAGTGCAACAATCCTCGCAACCCGACAGACGGAGGAGCAGGCGGAAACTGCGATTGCTCCACAGATCTTTTCGTACTAA
Protein Sequence: MLLHSHNFPQTAMAAPIEIENEIECASDWHLWCRLCAKDDLQGNINVFLKNEQSAPGGDRDGDAQEVAASAPIADMALATAIGKYFWVNITRGEELPEMICSECLTLVTSLVNFSERITRVQKLYCILQSTPKHDTISVQELRGRFGLIEEEQQLPEQPVPETLTEVHYVEEKPKLNELDVTVLELENPLTPAGKIEEKPTTEAVTPEAEEQQELEDEEVEEAVAEAADEQLEYEDAGTELLLNLCDAYSNEDSNGDSNSSSTKPKSKERGKAHQCNECPRAYALPQTLQRHMRQYHDKKSTADMKLLCCEECEKQFRSRYQLQRHMQQHLPMPKRKMYPCTSCGKKFTTNASAQSHAQYMHQEERPRPVICEQCGVGVHSLNALKEHLLSHTDYAPYECDVCKKCFKSLSRLKHHKETHDPHKYICPECGMQLNSRPTLNRHRLVHTDQMQHKCDYCGREFKRAKALKNHLILHTGLKPYSCDFCDRTFANGSNCRTHKKKSHPEELAAQEAAGGAKTYNRNIPKLEALKAFTKNKDNLSPVATKQSGCFAFGKKPKALIKSDASNSLQSSSVPSAAAAVGIIPTIDNIYNHIMKPPLATQQQQLLVTNGSATILATRQTEEQAETAIAPQIFSY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01322847;
90% Identity: iTF_00542636;
80% Identity: -