Dsil003142.2
Basic Information
- Insect
- Drosophila silvestris
- Gene Symbol
- -
- Assembly
- GCA_035043445.1
- Location
- JAWNMZ010000061.1:2514432-2523158[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.00025 0.017 15.5 3.4 1 23 301 323 301 323 0.98 2 11 0.0015 0.1 13.1 10.7 1 23 330 352 330 352 0.96 3 11 0.00012 0.0082 16.5 6.5 1 23 358 380 358 380 0.98 4 11 0.00038 0.025 15.0 2.3 1 23 386 408 386 408 0.95 5 11 2.7e-05 0.0018 18.6 0.5 1 23 414 436 414 436 0.97 6 11 2.4e-06 0.00016 21.9 0.1 1 23 442 464 442 464 0.98 7 11 0.00015 0.01 16.2 2.0 1 23 469 492 469 492 0.97 8 11 0.063 4.2 8.0 0.3 1 23 498 521 498 521 0.94 9 11 0.0002 0.013 15.8 0.1 1 23 580 602 580 602 0.98 10 11 0.018 1.2 9.7 2.7 1 23 716 738 716 738 0.95 11 11 0.0054 0.36 11.4 4.9 5 23 751 769 743 769 0.92
Sequence Information
- Coding Sequence
- ATGTGCGCTGCACAGAGCAATCCGCCGCCCTTCGGCTACACTTGGGGTTTTGCAGACAACGGCAACCGTGCCGCAGAATCAGTTTTGGAGATATCGCCAAATATTAACTACACTGTCAGTGGGGAATCGATGCCCTATCTGTTATCCACGGATGGATCATTGGCCGTACAAAAGGATGTTAAGGGCGCACTCTCCAGCAATAAGGGCAATGTCGTTCGTCGCATGTTCGTCGTGAACGATTCCTCATTTGCGCCCGGAACACAAAGAGTAATTACCACAGGCTCCGCATCGACGGTGGTCAAAAAACAGGACTCTGGTCAGCAGGTGTTGAGCATAAATTCGCTCGATAAGAATTATCTTTTGGTCGATcaggcaacagcggcagcagctgcagctgcagcagcagcgggcgGAGGAGGTGATCCGGCGGCagcccaccaccaccatcatcatcatcatacaTTGACAAATGGTGGCAGCATTGTTGATGCCAAAACTGGACAAACCGTATTAAcatcggcggcggcggtggcagcggCGAGTGCTGCGGCAGCCAAATCGCATTTTAGCTCAATCGGTGCACTGCATCTCACCCAAGAGGAGTGCAATGAGATACTAATTAAGCGCGCCATTGCAGCCGGCCACggccatcatcatcagacGCACCCAACAGCAATCAGCAACGCTGGCGACGGAGCGCACCATCATCATTCGGCGCCAGGCGCGACACCAATTCAAGTACAGAAAGTAATACAAGGACTCGAAGATAACGAGGACTCGCAGGGCGACGCACCCAACTTAAAGTTGGAGCCAGGCACATTAGAATTGTCCCCAAAGACCGAACTACAGGAATCAATGCATTTCAGCGAAACCGACGCCACCATCAAAAAGGAGCGCCCGTACAGTTGTGACGAGTGCGGCAAATCCTTTCTGCTCAAACATCATTTGACAACACACGCACGCGTGCACACAGGTGGTGAACGACCCCATATTTGCACACATTGCGGCAAGACTTTTGCGCACAAACACTGTCTGAATACGCATCTGCTGTTGCATTCAACGGATCGGCCATATCAGTGTCAGGAGTGCAAGAAGAGTTTCACACTCAAGCATCATCTGTTGACGCATTCCCGGGTCCACAGCCGGGAGCGACCGTTCGTTTGCCAGGAGTGCGGACGATCCTTTCCCCTCAAACGGCATCTGGTCACGCACAGTAAATTTCACGCCGGCGAACGTCCCTACGTCTGCGAGGAATGCGGTGAGAGTTTCGCACAGGAAAACCATCTGATTATGCACTCGCGcttTCATGGTTCATTGAATCCATTTGTTTGTCCTGATTGCGGTGCCTCGTTTCCAcgcaaatttcaattggttAATCACGGACGCATACACGGCAAGATACCACACTCCTGCACCGTTTGCGGCAAAGAGTTTCTACAAAAGCGCACACTAGTTTCCCACATGAGGCGCGTGCATACCGGCGAGCAGGCGCATCCCTGCGTCAGCTGCGGCGAAGGTTTCCTCACCAAGGCGGAACTGCATCAGCATGTGCGTGCGGCGCACAATGGCGTCAATCCCAATACGAGCAGCGCCACAATTATAGCCAATCAACAGcAGATACAACAGCCGCATCATCATCCGGGACATCCGCAGACCATAACCGTTGTCAGCAATCCGGCTAACTCAACGCTGCTCACGGTCTCCACAACCGATGCGAATGGCGTGGCCCGTCCACAATTCGTTTGCCGAGAATGCGGTAGCGCTTTTAATAGTCGGGAGGCGCTCGCCTTGCACTTGCGACTGCACACCGGCGACAAGAGTCTGATGACCGATTTGTGTGCGCTGACAGCGGCGCTGCCGGGACACTTTTTGAGTACGGCCAGCTTAAATCCGGGCACTGTGGTCACGGCCAATCCGAATATGGTTGGGCAGAGTCCGGTGCCGGTGCAAATCATATCATCGACCGGTCAGGTGATGTCGCAGACCACACTGGTGCAGGCCGCCAATTCGACGCATCCGCAAGCGGTGGTCACCGCCGTGCCCACAATGCCCCTCCACGGGCAACATCATCTGCAGCacatccagcagcagcagcagcagcaacaacatgtcGTCACCGTCTCACCGGCCAACAAACCCAAATCGCATTTCTGCGCCAGCTGCGGCAAGGGATTCGCCGCGAAACACGGCCTCATGCAACACAATCGCAGGCATCCGAATGGCGGCTGCACGGTGCGCACCCATGTTTGCGAGTGTGGAAAGGCGTTCTTCCAAAAGAATCATCTGATGCTGCATCAGCGCCAGCATTTGGAAACGAAGCCAGCCATATCGCAGCAACAGGAGGCCGacgtgcaacagcagcagcagcagcaacaacaagcagcagctgcggctgcagcagcagccgctggaCAACAATCCACACAGGTGGAGGTGCAAATATTGCCCGGTGGCCATGCCAAGGTCATCAAGTATGAGATCTGTCGAAATGTCCTGCAGGAGGAGCAATccgcccaacagcagcagcagcaacaacaacaacaacagcagcagcaggcatcaATGCATGCGGAATAG
- Protein Sequence
- MCAAQSNPPPFGYTWGFADNGNRAAESVLEISPNINYTVSGESMPYLLSTDGSLAVQKDVKGALSSNKGNVVRRMFVVNDSSFAPGTQRVITTGSASTVVKKQDSGQQVLSINSLDKNYLLVDQATAAAAAAAAAAGGGGDPAAAHHHHHHHHTLTNGGSIVDAKTGQTVLTSAAAVAAASAAAAKSHFSSIGALHLTQEECNEILIKRAIAAGHGHHHQTHPTAISNAGDGAHHHHSAPGATPIQVQKVIQGLEDNEDSQGDAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGGERPHICTHCGKTFAHKHCLNTHLLLHSTDRPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRSFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCPDCGASFPRKFQLVNHGRIHGKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRAAHNGVNPNTSSATIIANQQQIQQPHHHPGHPQTITVVSNPANSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNMVGQSPVPVQIISSTGQVMSQTTLVQAANSTHPQAVVTAVPTMPLHGQHHLQHIQQQQQQQQHVVTVSPANKPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQEADVQQQQQQQQQAAAAAAAAAAGQQSTQVEVQILPGGHAKVIKYEICRNVLQEEQSAQQQQQQQQQQQQQQASMHAE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01556276;
- 90% Identity
- iTF_00803779;
- 80% Identity
- -