Basic Information

Insect: Drosophila siamana
Gene Symbol: PRDM1
Assembly: GCA_035047445.1
Location: JAWNPP010000006.1:1641005-1645687[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 3.1e-05 0.0019 18.4 2.5 1 23 928 950 928 950 0.99

2 5 9.3e-06 0.00056 20.0 5.1 1 23 956 978 956 978 0.98

3 5 1.9e-06 0.00012 22.2 4.3 1 23 984 1006 984 1006 0.98

4 5 0.00065 0.039 14.2 2.4 1 23 1012 1034 1012 1034 0.97

5 5 0.00011 0.0066 16.7 0.1 1 22 1040 1061 1040 1061 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	3.1e-05	0.0019	18.4	2.5	1	23	928	950	928	950	0.99
2	5	9.3e-06	0.00056	20.0	5.1	1	23	956	978	956	978	0.98
3	5	1.9e-06	0.00012	22.2	4.3	1	23	984	1006	984	1006	0.98
4	5	0.00065	0.039	14.2	2.4	1	23	1012	1034	1012	1034	0.97
5	5	0.00011	0.0066	16.7	0.1	1	22	1040	1061	1040	1061	0.96

Sequence Information

Coding Sequence: ATGGACTTCATCAGCATCCACAGCAGCCGCATTCGGCGTCGCAGCCAGCCGCCAGCGCAGCAATCGCCAGTGACGATGAAGACGACGTCGTCAGGCAAtggccagcaacaagaacaacagcagcagcagcagcaacaacaacacatagCCATACAGCATCCACATGCGCATCACCCgaatcagcatcagcaacagcaacagcatccacatgcacatCATGCGCACCCGCATGCCAAGCTGCTGCGTCGCtcgcgcagtcgcagccgcagccgcagtcgcagtcgcagccggtCGCGCAGTCGGAGCCTGACGCCCGACGGCAGCCGCGACTACGATGTGACGCGCATGCGTGAGGAGGACTTTGAACGTCTGGCCGTTTACTTGGTGCCCGATGTGCAGGCTGAGCGCGGGCTGCCCAATCGGGCGGACAAGACGCTGCCGCGCAGCCTGACGCTCAAGTCATCGATGATCTACTCAACGCCAAATGTAAAgACTGAAGGAGTTTGGAGCAGCGGCGTGATTCCGCGTGGCACGCGCTTTGGCCCTTTCGAAGGCATTCCAACCTCAAACTATCCAAACGACAAGAACAAGGCGCGTTATTTCTGGCGGGTGCAGGGAACACGCCACATAACCTACGGGAATATTAAGATCTTCAAGGACGACGACTACTATTACTTGGATGGCTCCGATCGCTCGCAGTCCAACTGGATGCGGTACGTGGCCTCCGCGTACAGTCTGCAGGTGATGAACCTCGTCGCCTGTCAGCACCAGGAGAACATCTACTTCTACACCACCCGCGACATACTGCCCAACGAGGAGCTGATGGTCTGGTACTGCAAGGACTTTGCCAGCCGCCTCGGCTACGACGTCGATCCCGAGCGCACCATCTTCGGCGCCTGCAAGCaggacgtcgacgtcgaggaggacgacgaggacgagctGCCGCCGCACAAGAAACCCCACTACGTGATGCCCGCTGCGCCCGAAATCCCCGCCGAGGTCGCCGTCAGTCACATCACCTACGTGATGGGCCTGCATCTGCCAGGCGCCGCCCCATcgccagctgccgctgcctccaTCTCCGCCCCttcctctgtctctgcctcgaCCCAGTGCTGTCGACGCGCCAGTCCGCCGGCGCACGTGAGCACCACGACGACGTCAGCGGCGACTTCGGTGGGAGGAACGACGAACGCGCTGCATCCGCACATTCAGCATGGACGACACGCGTCCGTGATCATCGGACAGGATCGCTCGCCGCTGGGCGGCGGCTGCGACAAGGAGGCGGCCACGTCGTCCTCGTCGGCGGTCTCCGATCATCACTACGAGCACCAGCTGACGCCGCAGGACGGCAGCGTGCGTTCGGTGCGCTCCGACGAGGGCTACCACAGCAACGAGTGCCACGAGGACGGTCTGACGCCGCCCGAGGActccagcgacagcgagagcgagcacAACTATGTGCTCGACTGCTCCAAGAAGGCCATTGCCCCCAAGGAGACGGTGATCGCGCAGGCGCAGAAGCCCAACAGCGTCTCGCCGCCAGCGCCCCCGACGCCACCGCAGCCTcctcaacagcagctgcagctggaggcgGACAAGAACGAGTATCGCAAGTTCAAGGTGAAGATGCCGCTGAAGTACGAGTTCAAGAGCAACAAGAGCTGCGTCAAGCAGGAGCCGCTCAAGGACGTCGACGAGCACCTCGCGCCCTCCGCCCACAGCCTCGAGGACGAGGAGCTGCACGAGCTGCATGCCGCCGTCGTTGAGGACGCACTCTGCCCGCCCAGCACGACCAGCACGCTGGGCGAGGAGTCCGCCGGGCAGCTGGAGGCGCCGGCCAACAACCCACAGCCCGCCTCCTCCACGGTGATTGTGCTCGAGCACAATCGCACCATCGTGCCGCTGAGCAAGCCCTACTACGAGAGCGATCCCCCTGCGCTGCCCGGCGAGCGCTACGTGCGCTTCACGCAGCCCAGCTCGAGCATCCTGGAGACCATTCTCACCAGCCAGCACCGCCTGGAGGCAGCTGCCGCGGCGGCGAACGCGTGTCGCCAGGCAAACGCTGCCACGCCGCCGCCCACGTCGCCCACCGAGATGGCGTACAGTTACAAGAAGTCGCAGCGCTATGGGAACGCAGTGAGTCCCGACTCCAGCTCGAACCTGGGCCAGTCGCAGGAGCTGCTGGCGACGCCGCTGGTCGAGCAGGGCGCGTGTGCGACGCTGATCAAGGGCGAGTGCGCGACGCTGATCAAGGGCGAGTGCTCGCCGCCCCCGGcgacctcctcctcctcctcctcagcCTCCTCGGCATCCTCCACGCACAACctgcaccaccagcaccagcatcagcagcaccaccagcaccaccatcaccaccacaaCGTCATCTACTCCCCAGGCGGGCACTCGCCCAGCTACGCTGGCTACGCGGGCTATGCGGGGGCGCAGTCGCTGCACGCAGCCACCTCGACGTTCCACTCGCCGCCGCACAGCTCGCACTCGCCCTTCGACCGGCAGTCGAACGCCTCCAGTGGCGGCGGGTCGGCCTCCAATCTGCATCTGCTGCAGAGCAGCACCCAGATGCTGAACCATCCGCTGATGCAGCCGCTGACGCCGCTGCAGCGGCTGTCGCCGCTGCGCATCTCGCCGCCCAGCAGCCTCAGTCCCGACGGCAACTCGTGTCCGCGCAGCGGCAGCCCGCTGAGCCCCAACTCGCTGGCCTCGCGCGGCTACCGCTCGCTGCCGTATCCGCTGAAGAAGAAGGACGGCAAGATGCACTACGAGTGCAACGTCTGCTGCAAGACTTTCGGCCAGCTGAGCAACCTCAAGGTCCATCTGCGCACGCACTCCGGCGAGCGGCCGTTCAAGTGCAACGTCTGCACCAAGAGCTTCACCCAGTTGGCCCACCTGCAGAAGCACCACCTGGTGCACACGGGCGAGAAGCCGCATCAGTGCGACATCTGCAAGAAGCGCTTCTCGAGCACCTCCAACCTGAAGACGCACCTGCGGCTGCACAGCGGCCAGAAGCCCTACGCCTGCGATCTCTGCCCCCAGAAGTTCACGCAGTTCGTGCACCTCAAGCTGCACAAGCGGCTGCACACCAACGATCGGCCGTACGTCTGCCAGGGCTGCGACAAGAAGTACATCAGCGCCTCGGGGCTGCGCACCCACTGGAAGACGACGAGCTGCAAGCCCAACAACCTCGAGGAGGAGCTCGCCATGGCGGCGGCCGCCACCTCGGAGTGTCTCGACAAAGACTTGCCGGAGCCGGACTCGCGCGAGGCctacgagcagctgcagcagcacatgcATCCCGTGCACCCGAGTCTGCGTCACCTGGCTGGCGGCCAGTCGCCGCCTCGCCTCATTCCCCTCGGCAGCAACGGGCCCCCGCCTCAACTGCACCAGCCCCAGCATCCCCAACAGCCACAGTCGCCCGCCGGACACTTGCTGCAGGCGCCGCCCATGCTGCTGACCACCgccaaccaacagcagcagcagcagcagcagccgcctgtggagcagctgcagcacttgGGCCCAGCGGGTCACCATCTGTCGCCCAAGTCGCTGAAGCAGGAGGCCGCTGGTTACCTGCACGGCCACATGCACGCTCATCCGCATGGCCATGGACTCGCCcatggacacggacacggacatggacacggacacggacatggacatgggCATGGACATGTGCAGGCGCAGGAGAATCGGCCGTCGGTCATTGAGTCCTCCAACCAGCCCATGATCATCGAGTGCACGTAG
Protein Sequence: MDFISIHSSRIRRRSQPPAQQSPVTMKTTSSGNGQQQEQQQQQQQQQHIAIQHPHAHHPNQHQQQQQHPHAHHAHPHAKLLRRSRSRSRSRSRSRSRSRSRSLTPDGSRDYDVTRMREEDFERLAVYLVPDVQAERGLPNRADKTLPRSLTLKSSMIYSTPNVKTEGVWSSGVIPRGTRFGPFEGIPTSNYPNDKNKARYFWRVQGTRHITYGNIKIFKDDDYYYLDGSDRSQSNWMRYVASAYSLQVMNLVACQHQENIYFYTTRDILPNEELMVWYCKDFASRLGYDVDPERTIFGACKQDVDVEEDDEDELPPHKKPHYVMPAAPEIPAEVAVSHITYVMGLHLPGAAPSPAAAASISAPSSVSASTQCCRRASPPAHVSTTTTSAATSVGGTTNALHPHIQHGRHASVIIGQDRSPLGGGCDKEAATSSSSAVSDHHYEHQLTPQDGSVRSVRSDEGYHSNECHEDGLTPPEDSSDSESEHNYVLDCSKKAIAPKETVIAQAQKPNSVSPPAPPTPPQPPQQQLQLEADKNEYRKFKVKMPLKYEFKSNKSCVKQEPLKDVDEHLAPSAHSLEDEELHELHAAVVEDALCPPSTTSTLGEESAGQLEAPANNPQPASSTVIVLEHNRTIVPLSKPYYESDPPALPGERYVRFTQPSSSILETILTSQHRLEAAAAAANACRQANAATPPPTSPTEMAYSYKKSQRYGNAVSPDSSSNLGQSQELLATPLVEQGACATLIKGECATLIKGECSPPPATSSSSSSASSASSTHNLHHQHQHQQHHQHHHHHHNVIYSPGGHSPSYAGYAGYAGAQSLHAATSTFHSPPHSSHSPFDRQSNASSGGGSASNLHLLQSSTQMLNHPLMQPLTPLQRLSPLRISPPSSLSPDGNSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDLPEPDSREAYEQLQQHMHPVHPSLRHLAGGQSPPRLIPLGSNGPPPQLHQPQHPQQPQSPAGHLLQAPPMLLTTANQQQQQQQQPPVEQLQHLGPAGHHLSPKSLKQEAAGYLHGHMHAHPHGHGLAHGHGHGHGHGHGHGHGHGHVQAQENRPSVIESSNQPMIIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00553931;
90% Identity: -
80% Identity: -