Basic Information

Insect: Drosophila siamana
Gene Symbol: -
Assembly: GCA_035047445.1
Location: JAWNPP010000004.1:19723870-19726169[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 3e-05 0.0018 18.4 2.5 1 23 434 456 434 456 0.97

2 7 6.9e-05 0.0042 17.3 0.2 1 23 462 485 462 485 0.97

3 7 0.0036 0.22 11.9 1.5 1 23 491 514 491 514 0.90

4 7 7.8e-06 0.00047 20.3 1.5 1 23 552 574 552 574 0.97

5 7 0.00055 0.033 14.5 1.6 1 23 580 602 580 602 0.98

6 7 0.00017 0.01 16.0 0.4 1 23 608 630 608 630 0.98

7 7 0.0025 0.15 12.4 2.5 1 22 636 657 636 660 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	3e-05	0.0018	18.4	2.5	1	23	434	456	434	456	0.97
2	7	6.9e-05	0.0042	17.3	0.2	1	23	462	485	462	485	0.97
3	7	0.0036	0.22	11.9	1.5	1	23	491	514	491	514	0.90
4	7	7.8e-06	0.00047	20.3	1.5	1	23	552	574	552	574	0.97
5	7	0.00055	0.033	14.5	1.6	1	23	580	602	580	602	0.98
6	7	0.00017	0.01	16.0	0.4	1	23	608	630	608	630	0.98
7	7	0.0025	0.15	12.4	2.5	1	22	636	657	636	660	0.91

Sequence Information

Coding Sequence: atgaaGTGCGCTGTGCATAACTGCACAAACAAGTTTAAGTCCCGACAAAAACACTCACAGCAATTTAGTTTCTTTAGCTTTCCGAAAAATCCAGAGATTTTAAAAAAGTGGTTCCTGTTTTGTCGGAAGAGCAACAAAGACAAAGTCAAAAGCTACCTAAAGAGCGTCATATGCAATGAACACTTCAAGGAGGAGGACATTCAGGGGGGATTGCAATTTCAGATggGTTTATGCTCGAAGCGCACACTGAGACCAGGAGCAGTGCCGTGcatcaataaaaatgatattaGCGAAGCTGAACGTGAGATGTCGGAGAAGCTTAAGAATCAAAAATTGGTGGCTGAGCTACTCGAGGAGGCGGAAGCACGTGAGGCAGCAGAGGCCAGTGGAGCAATTACCATTGCCCCAGATTTCGTGCGCAATACAGGCATTGTCTCTGTCCCGGATTTTGTCAGCGCCACCGGAAATGCCTTCGTTTCGTTTACTCCCATGCCAATAGAGACAGATCCCTTAGCTGAGGAACAGACGGCTCAGGAGATGAAAATGATAGCTGAGAACAAAAGTAAAAAGGTTGATCCACCACTAGCACCATTGATTGAGCAGAAAAAATGTCGCACGTGTGGTCAATTTTTTGTCGTTGACGATAAAGCGAAAGATCTGTGCTGTGAACAAAACGCTGTAATGTTATATCACATTGAAGTGATTACGGGAATTTGGatcCAATGTCCTGATGAAATATCACGATTCATGTGCGCCAATTGCGTGGACAATTTACGCATCGCTATCGAGTTTCGTGAAACATGTATTAGAACAGAGCTTCAGCTGCAAGGTGGTGACGATATGGAAATTGATAGCCAAGTTAAGGATGAGATGGAAATTTGCAATAATGAGGTTCAACCTCAGCCGATTGTTgtcaacaacaatgacagtgatataaaaacaaatgaatatgTTACAATATTACCGGCAGAAGAGGAAAGTGGGCAACCCATCATGGTAGAGCCTATAACGCATGCAGGAACTAGAAAAACCGGTCAGGTGACGCACCCAGGATCAGGAGATTCGAAGAGCATAGCGTTGGGGGCGCAGATCTATGAAGACCTTTTAAACGAGTATAGAGGCATGGATAAACTGCCACGTCCCCGGAACAAGAAGGCAATTGCAACGCCAATATCAAAGACGCAAGTGATTAAACAACGAAAGCGACGAGTGCaggagaaaaaacccaaacgCACAAAACGTACGAGAGAAGAGAAGAATCGCATACGTCGCGAACAAATCAGAGCACTGCCACTCAATCATGTCTGCGACCAATGTGGTGCTTCCTTTCGAGTGCGATGCAATCTTACCATACATATGCTGCGGCACACTCGCACCAAGAATTATCCATGCCCCGAGTGTCCCAAGCAGTTCTATGATGCGTATATGAGAAACATGCATATCCGTGTTCGTCATCGCGGAGAACTTCCATTTGTGTGCAACTATTGCACCAAAGCGTTTAGTTCGTCGAACACGCGTTACCTGCACGAAAAgAACGTTCATGGAGCATCGCCACGCATTCACCGCAATGTGAATAAATTGAATCAGAGACTCGAGATCAAAGACAAGTCATCGCAGCCGCCGCAGGAGCCACAGCCAAAGGAAAATATTCGACATTACTGCAACTATTGCGATAAAAGCTATGCAACAAAATATGCGCTAAATGGTCATATCAATCTTCACTTGGGACTCACGCCTTTCAAGTGCAAGCTCTGCGATATGCGATTCGCGGATCCACAATCGAAAAAGAAGCATGAAATGAGGCACGATAGCAAACGGCCCTTTGAATGTGACATTTGTCTCAAAGGATTTTATGTTCGCAGTAAACTGAAGGAGCATGAACGTATTCATACCGGCGAGCGTCCTTACAGGTGCGACGTTTGTGATGCATATTTTCGATACAAGTTCAACTTGTATTCGCATCAATTCAGCAAAATGCACAAGGACAATCTGCTAAAGGTACAAAAAGAAGAGATTGTGGAAGACTCAAATTGA
Protein Sequence: MKCAVHNCTNKFKSRQKHSQQFSFFSFPKNPEILKKWFLFCRKSNKDKVKSYLKSVICNEHFKEEDIQGGLQFQMGLCSKRTLRPGAVPCINKNDISEAEREMSEKLKNQKLVAELLEEAEAREAAEASGAITIAPDFVRNTGIVSVPDFVSATGNAFVSFTPMPIETDPLAEEQTAQEMKMIAENKSKKVDPPLAPLIEQKKCRTCGQFFVVDDKAKDLCCEQNAVMLYHIEVITGIWIQCPDEISRFMCANCVDNLRIAIEFRETCIRTELQLQGGDDMEIDSQVKDEMEICNNEVQPQPIVVNNNDSDIKTNEYVTILPAEEESGQPIMVEPITHAGTRKTGQVTHPGSGDSKSIALGAQIYEDLLNEYRGMDKLPRPRNKKAIATPISKTQVIKQRKRRVQEKKPKRTKRTREEKNRIRREQIRALPLNHVCDQCGASFRVRCNLTIHMLRHTRTKNYPCPECPKQFYDAYMRNMHIRVRHRGELPFVCNYCTKAFSSSNTRYLHEKNVHGASPRIHRNVNKLNQRLEIKDKSSQPPQEPQPKENIRHYCNYCDKSYATKYALNGHINLHLGLTPFKCKLCDMRFADPQSKKKHEMRHDSKRPFECDICLKGFYVRSKLKEHERIHTGERPYRCDVCDAYFRYKFNLYSHQFSKMHKDNLLKVQKEEIVEDSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00579513;
90% Identity: iTF_00595279;
80% Identity: iTF_00595279;