Basic Information

Insect: Drosophila siamana
Gene Symbol: Trerf1
Assembly: GCA_035047445.1
Location: JAWNPP010000004.1:29290094-29300040[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.00014 0.0084 16.3 0.2 2 23 351 372 350 372 0.97

2 6 4.3e-06 0.00026 21.1 1.3 1 23 378 400 378 400 0.98

3 6 0.00043 0.026 14.8 2.5 1 23 406 430 406 431 0.94

4 6 0.00072 0.043 14.1 0.8 2 23 728 749 727 749 0.97

5 6 0.045 2.7 8.4 0.1 1 23 1877 1901 1877 1901 0.94

6 6 9.6e-05 0.0058 16.8 0.8 1 23 2030 2052 2030 2052 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.00014	0.0084	16.3	0.2	2	23	351	372	350	372	0.97
2	6	4.3e-06	0.00026	21.1	1.3	1	23	378	400	378	400	0.98
3	6	0.00043	0.026	14.8	2.5	1	23	406	430	406	431	0.94
4	6	0.00072	0.043	14.1	0.8	2	23	728	749	727	749	0.97
5	6	0.045	2.7	8.4	0.1	1	23	1877	1901	1877	1901	0.94
6	6	9.6e-05	0.0058	16.8	0.8	1	23	2030	2052	2030	2052	0.98

Sequence Information

Coding Sequence: ATGTGCAGTGCTTCTGTTGGCACTGAGGGTTCTTTGACACTGCAACTGCGAGATGGCAATGAGAGTGCTGGTGTGACTCCAAATGCGAATGTCTTGGAGCCAGCAAGCAGTATATCAGgcgtaacagcaacagcaacagcaacaacaacaacgacttcaACCCCAACGAAAGTAAAGACTAGTGTATCAGTAGCAccagcgtcagcgtcaagCATCACAGTGCTTGAGGCATCGtcagcttcagcatcagcatcagcgtcagcaTTAGAGAATGCATTGACCATTGGCTATCCGGATCCGGACATGTTAGCAGATGTTTTAGGCACCATACAGACAGCCTCTCTTAAAAACAAgcatagcaacagcaacaacaaatacgacaacagcaaaagaagtagcaacaacaacaacactaccAGCAGTAGCAGAAATGGCGCACctacaattttaaattcaagctctggcatttatttgaataatcCGAATAAGATAACCATAACTCGACGGAGTTCGAGCAATAAGATCAGCGTGCAGACAGTGAGCGCTTCAACGAATACAACTATTTGCAGTATAAGCGGTAATAAGACTAACTATATTAAGAACTGTCTTatacgcagcagcagctgtagcaACACTGCCACCAATGTCACGACACTGGCGCAGATtatgagcaacagcagcacgagCAGCGCGGCCAGTTTACTCAGTCAAcataacaataatagcaactgtagcaacagcagtaacTTTAGCAACGCCTCCTCTGTGGGGAGCAGCATTAGCATTGGCAGTACCTGTAGCAACACTTCCtccatcagcaacagcaacagcaacagcaactgcaacagcaatagcaacgacagcaactgcagcagcagcggtggaCATAGTTCAAGTTTTAAGAGCAACAACGGTCGAAATGTTCCTGGCGtagtcacagcagcagcatccacaaATACCACAGCAactggcattggcattgtaACCGTCGACACCGCGCCTCGAAAGAGCCGTCCCAAACTATCTTCGCCAACACGACACGGACCACAACAGTGCCAGATTTGTAGCAAGATCTTTGGAAATGCCTCGGCGCTGGCTAAGCATAAACTGACGCACAGCGACGAGCGGAAATATATTTGTGCGCTCTGCTCGAAGGCATTCAAGCGGCAAGATCACTTAAACGGACACATGATGACGCATCGCAACAAGAAGCCTTACGAATGTAAGGCGGATGGTTGTGGCAAATCGTACTGCGATGCCCGCTCTCTGCGACGCCATTCGGAAAATCATCATGGAGGTGTCACGGCGCAAGCGAACAACACGCCTTCAGCCACATCGGCTGCAGGCACTATttgcagcggcagtggcagtggcaatggcagcggcagcggtaaCGGCAGCAGTTCCAatagcagtggcagcagcaacagcaatgcggTGACCAACTCTTTGAGTCTGTCGCCGGCCACGGCCAGCGGAGATGCCAGCTCACCGGATGGGGCTACGTGCATACGCACCTACATCTCCACAGGCAGCACTGTGGTGGACGCGGCGACAGGAATCGCGTTGTCCGAGGAGCAAATCAAAGCGATGAATCTGCCAATTAAAACGGGCGTCACATTGCTATCGCCCACAACGTCTGTATCCTCGAATGCGTCCTCCACAGCATCCACATCTTGCTCCTCATCCAACGGCAGTGTCAGTGGCACAGGCAGCGTCAGCAtcagtggctgtggcagtggtGGTAGCGGCAAAAGCAGCACCAACACATCAACTGCCATGGCCAATTCACCCACCATAACACTCAGCGATGGCACTATGCTTGAGGGCGAGGGACTCACACGGGAGCAGCTAGATCTGATCAGCAAGATTATGCAGCAGACGAAGCAAACCAGCGCCCAAGTGACTGTCTCTTCTCCTACTAGTGTCAGCTCCTATAAGATCAATACAGAGACAACCCCAGTGCTAACTCGACCACGCACCTGGAACATGCAATTGcTAAACAATGCCCAGAACGTGACTGTAACGGTTGAGGATGGCACTGATCTTGTCGCCACTGCTGGCAGCTCCAattccagctccagctcgcaTGATGACGTCAAAGAGGAGGAGCTGAGCCAGCAGATAGTAGCTGCGATCAATCCGCACCTGCTCAATATTGTGAAGATCGACAAGCCAGTAGAGTGCAACTTGTGCCACCGTAAGTTCAAGAACATACCTGCCCTCAACGGGCACATGCGTCTGCACGGCGGCTACTTTAAGAAGGATCCCGAAACGAAGCGAAGTGAGAAGAAGGACGTCAGTGGGCCGCCATTGCAGACGGCTAGCATCGGGGTGCGTGCGCTCATCGAGGAGAAGATCATTAGCAAGCGCAAAGACATCTCTAAGGGCTCCTTCGTCGTGCCTGCTCCACCTGGCAGCTCAAGCAACTGCGTCCCTGGTAATGTTTCTGGCGTTACTGCTGTTAGCAGCGCTGGGAATCAGAGCAATAGTTGTCTGAGGCGTTCTGTAAGCGACTTGGAGAGCTTTCTAaatgccaaaagcagcagcaacaaccttAATCATACTAGCGCCAGCACAACGACAGCCTTATTGCCGGCAGCAACCACAATTAAGAGTAGCAATGGACTAAGTATTCAACAGATTGACTTGCCTCAAAGCATCGAGATCTTTAGCGGTTGTcaaaggcagccaaaaacGCTTAGCTTGGGAAGTGGCGCCAATACCATTACCATAACCACCAACAATGTGCCTACCACGACCACAATGAGTGCTCTCACGGCATTGAAGGGCGGCAGCAATCTAAGCGGCGGCGTTGCCAACCATGCGACTGATCCCAAGGACTCGACCCTGATCGAACTGCTCAAGCGGGGCACTCGCATTGCTGTGACTTCCAAGAAGACCCAGTTTCAGACGCAAACCAGTACAAATCTTCTGCTAAGCAGTGTGGCAGGCACTGAGCTGACGACCATTGGCAGCAGTATCCAAGCAGGTCGTCAGATTATCACGAACAACAACCGCACAGTCATCATACCCTCGGATGTCCATGTTGTATCCACAAAGAGCAAGGTGATCCCCAGCAGCGCCGGCAGCTGTGGTAGCGCCAACAACGTCACCAGTGTCATCAACAGTAGCAATAGTGGCTGCTCCACAAGTAGCATTTCCTTGGCGGACGGCACTCCGCTTTCTCTGTCCTTGGCACCCAATCAAGAAAACATTAGTGCTCTGACCGAGACGAGTAGCATTTCGAGCAGGGGAGGCGGTGTTTATACGGTAACTTATACGAGTGATGCGGATGCATCAGATCTATTTGATGATACCGAGGTGTACAATGTCGCAGATACGGAGATGTTATTGCAAACTGTGGACACCATGGAGCTGCTgcacgacgacgatgaagagCCCCAAACAAATGAACATTCCAATAACTTTGCCCTCCTCAACGAGACTGCCGGCACAGATCACGGCCAGCAGTTGGTGAAATTAGAGCCGGAGTCCGGTCAGAGTATCCAAGTTAGTCACACCACTCCGCTACCAACTTTCCAGCAATTCCATTCCAAAGAGCTGATCATGCAAAACAGCTCGCAGATCCAGGCCATTGCCAATATGCGAGGAGGCAATAGTAGCGCTCTTGGAGTGCTCGCGTCACCTCTGCATTCACCTCTGGCCTATCCGACGCCGCCATCTAGCCACGAGAATGTGGCGCAATCCTCCCCATTTATCGAGGATGCCGCGGCTCAGTTTGTTGACGCCAATCACAGTTTCTTTGGCGACAAGACGGACTTCTCCCACGTGTATTTCAAGACAGACGAAAGTCATCATTCCCTGCATCAACCCGAGCTGAGCGACAACGATACCGAGAAGAtacttaaattgaaatgcgttTTGGAGGAGAGTAGCTTCGATCCGTCCATCAAAGTAGAGGATCTTTTGAATAACACTGAGGATGATACCGAATGCGATTTGCACGAGTTCGCCGAAACAAATCTTTCGTTTCTCGACGAGGATCAGGAGTTTCTCAACAATTCGCATAACGCCACTTCGCCGCTATCTGAGTCGTTTTTCACCAGTGGAATTGGTTCTGCGGAGGATGTGAAACAAGTGCTCCGCGAGGTGCTGCCTGATGAAAATATGCAGCTACAATTGAGCAGCGAGCAACAAGGCGAGAATATCATTGATCTCTACTATTTGCCAGGCTTGGGGTTGCAATCACAAATGATGCCCAATTCTGATGATCCCTTGCTCTCATCATCGCCGCGTGAATTTGGGCAGCAAAGACAGGTGACGCTTCAGAGCATATCTTCCACGTCAGCTACTGTGCAAGCTGTAGAGCCATTGCAATCATCAACTGTGATTTTCGAGCAACACCAGTtggatcaacagcagcaacagcaactgcggcAAGATCAACAGATGCAACAGATATTGCCACAACAAGACGTCATTCAACCGGAACAAAggcaatcacaacaacagcagccgcagcagcagcagcatcagcaatcCGAGTTTATGCTGCCCACATTTAATCAGGCCCCTTGCCAGCCGACACAGTATCTAGATGCTAGCCAGTCAATGCCTATGACTTTGCAGCCACTGAATAACATAATGCAGCCAATTTCTTTTGGCAATGCTGTAGGCGAAAAGCAAGAGTTTAGTACGCTGCACAATAGCCGCACAGGACATGCAACAGTTCTCGATGCCAGTCTCCTTTTTGGCTGTGTCGATGGTGATAGCAACAAGACTGTTAATGCTACAGTCGTAGCCACAGCTCCAACAACACCTGCAGTGCTTCCCAGCCCAATGAGTACAATCACAGTCACTGGAAGTATATCCAATCTGCACCCATTGTCAAATCAAACAAACTCCATCCTGAAGAGACGACTACGTCCCAATGGAACACAGGATATGCACAAGCTATCGAAATTTCATACTCTCTCGCCGCATCGCTCAAAGCTACGGAAGCCCTCTCGCACTCATTACACTCCGGCTCCTATACTCAACCCTGATCGCAAAGGCACAGGACTCTATTGCAATGTGCGAAAGCAACTCGGTCAGGGTATATTTGATAATTTCGATGATGATTTTGGTGATCCAGTCGGCCTCGTGGACTTCTCAGATGAGTCAAAGGTAAATCTGGGCTCGACTTACCAAGCACAGATACCCGCCTGGAAACCACTCGATGATTACCTCAAAGAGTCATCAACGAGCTGTGGAGCGGACTTAATGTGGGACCCAAATGTGCAACTTGATGATAAGATACTCATGCGCTATATAGACCTAAGCAAATCATCGGCAGTTCCCATGGGCAGCCATTCGGAGGAAATGGCATTGCAAACACTTCTCGATGCCAAGGGTAATTCAGCGGCGGCAGTTTTAACACTTCTCCAAACACAGTCGagtgcatttcaaatgaaatggacTGCTTTCGAGCTGGAGCAGTTCCTGCGTGGCCTTGAGAAGCATGGCAAGGACTTCGCCAAAATCACTAGTGAGTTATGCACAAAGACATCGGGTGAGTGCGTACAAATGTATTACTTTTGGAAGAAACTTTGTGTGGACTACAAAGTATCTCACTTAAAAATGGAGCCGGTTGTAACGAGCACCCCTACTGTGGAACAGAAGCCCTATGTCTGTGAGATTGCCGCCTGCTCTGCGAGCTTTAGCTCGAAAGCGGCACTGCATGGTCATGTTCGAATACACGCTTATGGTagaaatgccaacaacaacaacaataaccacaaCAATCAGCATGCGACGGCAattaatgccaacaacaacagcaactgcataagcagcagcagcagcaacaacagtaacaacaatcatagttccagcagcagccacaatatCAATAGCAGTAATGCATGCACAACCCTGACTAGCAGCATtaatgcaataacaacaacaaccataaccAACACCAATAACATCGCTGTGAACATcaatagtaacaacaacagcaacaacaccaattcCTTAAACTCGACGCTTTTGCTGACAGCGCCAGGAAGTAcattgccagcaacaaaagacagcagcaacagcaacagcaacggaaACTCGAATATTGCCAAGGATAGCGAATTCCCCTGCAAGGTGTGCGGCAAGGTCTTCAATAAGGTTAAGAGTCGCAGCGCTCATATGAAAACTCATCGTGTGCAGGAATCGGATCAATCATCCAATTGCAAACAGCAGTCCCACCCCCATGGAAATCTGCCTTCAGTTATAGCTGTCACTGCGGCATCCTCATCAGTATTGGTTATGGCTTCAACATCATCATAG
Protein Sequence: MCSASVGTEGSLTLQLRDGNESAGVTPNANVLEPASSISGVTATATATTTTTSTPTKVKTSVSVAPASASSITVLEASSASASASASALENALTIGYPDPDMLADVLGTIQTASLKNKHSNSNNKYDNSKRSSNNNNTTSSSRNGAPTILNSSSGIYLNNPNKITITRRSSSNKISVQTVSASTNTTICSISGNKTNYIKNCLIRSSSCSNTATNVTTLAQIMSNSSTSSAASLLSQHNNNSNCSNSSNFSNASSVGSSISIGSTCSNTSSISNSNSNSNCNSNSNDSNCSSSGGHSSSFKSNNGRNVPGVVTAAASTNTTATGIGIVTVDTAPRKSRPKLSSPTRHGPQQCQICSKIFGNASALAKHKLTHSDERKYICALCSKAFKRQDHLNGHMMTHRNKKPYECKADGCGKSYCDARSLRRHSENHHGGVTAQANNTPSATSAAGTICSGSGSGNGSGSGNGSSSNSSGSSNSNAVTNSLSLSPATASGDASSPDGATCIRTYISTGSTVVDAATGIALSEEQIKAMNLPIKTGVTLLSPTTSVSSNASSTASTSCSSSNGSVSGTGSVSISGCGSGGSGKSSTNTSTAMANSPTITLSDGTMLEGEGLTREQLDLISKIMQQTKQTSAQVTVSSPTSVSSYKINTETTPVLTRPRTWNMQLLNNAQNVTVTVEDGTDLVATAGSSNSSSSSHDDVKEEELSQQIVAAINPHLLNIVKIDKPVECNLCHRKFKNIPALNGHMRLHGGYFKKDPETKRSEKKDVSGPPLQTASIGVRALIEEKIISKRKDISKGSFVVPAPPGSSSNCVPGNVSGVTAVSSAGNQSNSCLRRSVSDLESFLNAKSSSNNLNHTSASTTTALLPAATTIKSSNGLSIQQIDLPQSIEIFSGCQRQPKTLSLGSGANTITITTNNVPTTTTMSALTALKGGSNLSGGVANHATDPKDSTLIELLKRGTRIAVTSKKTQFQTQTSTNLLLSSVAGTELTTIGSSIQAGRQIITNNNRTVIIPSDVHVVSTKSKVIPSSAGSCGSANNVTSVINSSNSGCSTSSISLADGTPLSLSLAPNQENISALTETSSISSRGGGVYTVTYTSDADASDLFDDTEVYNVADTEMLLQTVDTMELLHDDDEEPQTNEHSNNFALLNETAGTDHGQQLVKLEPESGQSIQVSHTTPLPTFQQFHSKELIMQNSSQIQAIANMRGGNSSALGVLASPLHSPLAYPTPPSSHENVAQSSPFIEDAAAQFVDANHSFFGDKTDFSHVYFKTDESHHSLHQPELSDNDTEKILKLKCVLEESSFDPSIKVEDLLNNTEDDTECDLHEFAETNLSFLDEDQEFLNNSHNATSPLSESFFTSGIGSAEDVKQVLREVLPDENMQLQLSSEQQGENIIDLYYLPGLGLQSQMMPNSDDPLLSSSPREFGQQRQVTLQSISSTSATVQAVEPLQSSTVIFEQHQLDQQQQQQLRQDQQMQQILPQQDVIQPEQRQSQQQQPQQQQHQQSEFMLPTFNQAPCQPTQYLDASQSMPMTLQPLNNIMQPISFGNAVGEKQEFSTLHNSRTGHATVLDASLLFGCVDGDSNKTVNATVVATAPTTPAVLPSPMSTITVTGSISNLHPLSNQTNSILKRRLRPNGTQDMHKLSKFHTLSPHRSKLRKPSRTHYTPAPILNPDRKGTGLYCNVRKQLGQGIFDNFDDDFGDPVGLVDFSDESKVNLGSTYQAQIPAWKPLDDYLKESSTSCGADLMWDPNVQLDDKILMRYIDLSKSSAVPMGSHSEEMALQTLLDAKGNSAAAVLTLLQTQSSAFQMKWTAFELEQFLRGLEKHGKDFAKITSELCTKTSGECVQMYYFWKKLCVDYKVSHLKMEPVVTSTPTVEQKPYVCEIAACSASFSSKAALHGHVRIHAYGRNANNNNNNHNNQHATAINANNNSNCISSSSSNNSNNNHSSSSSHNINSSNACTTLTSSINAITTTTITNTNNIAVNINSNNNSNNTNSLNSTLLLTAPGSTLPATKDSSNSNSNGNSNIAKDSEFPCKVCGKVFNKVKSRSAHMKTHRVQESDQSSNCKQQSHPHGNLPSVIAVTAASSSVLVMASTSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00589779;
90% Identity: iTF_00595184;
80% Identity: iTF_00595184;