Basic Information

Insect: Drosophila siamana
Gene Symbol: BCL11A
Assembly: GCA_035047445.1
Location: JAWNPP010000078.1:10768182-10784727[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.028 1.7 9.1 2.4 1 23 302 325 302 325 0.95

2 6 2.8e-06 0.00017 21.7 1.0 1 23 812 834 812 834 0.97

3 6 0.013 0.78 10.2 4.7 1 23 840 862 840 862 0.99

4 6 1.2e-06 7.2e-05 22.8 3.2 2 23 1174 1195 1173 1195 0.97

5 6 1.6e-05 0.00095 19.3 3.3 1 23 1201 1223 1201 1223 0.99

6 6 2.9e-05 0.0017 18.5 0.4 1 22 1231 1252 1231 1252 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.028	1.7	9.1	2.4	1	23	302	325	302	325	0.95
2	6	2.8e-06	0.00017	21.7	1.0	1	23	812	834	812	834	0.97
3	6	0.013	0.78	10.2	4.7	1	23	840	862	840	862	0.99
4	6	1.2e-06	7.2e-05	22.8	3.2	2	23	1174	1195	1173	1195	0.97
5	6	1.6e-05	0.00095	19.3	3.3	1	23	1201	1223	1201	1223	0.99
6	6	2.9e-05	0.0017	18.5	0.4	1	22	1231	1252	1231	1252	0.97

Sequence Information

Coding Sequence: ATGTACAACAAAATGCTGTCGATCAGTGAGGATCATGGATTCCGTTCGCTGAGCCATTCCGACTCCACAGAGAACGATGCCGTCGCCGCGCAGGACATCCTCACGTGCGGCGCCTGCCAGAAGACCTTCGCGCTGTCGGACATCGTCCGCTTCATCCAGCACAAGGTGCTGCAGTGCAACAAGGAGAACTACGGCCAGTGCACCACGCAGGCGCCCAGCATGGACCGCGACGCCGACGAGGGGCGTCCGCTGAGTCTCGTCAATCGCCGGCCCTCCATCTCGGCGCCCATCACAAACGCGTCACGCAAATCGGCGCCCGTCGCCAGCACGCTGCCCCCCGCGGCCAGCGGtgccgccagcgccgccgcgGCCGCcacagcggctgcagctgccacagcggccgcggctgccacagcggcggcagcggcagcggcagcagccgccacagcagcggccGCCAGCGGCTCACGCATCCACACACCGCCGCCCAGTCCGGCGGATCTGTTGGCCGACGGCGCCAGCAGCACGCCCAAGCGTCTGGTGGACGAGAACGACAATACGACGCCGAAGACGGACGGAGGCGATGGCTTGAACCTCGAGCAGTCGGCGCACATTGTGCGCAGCGACGACTGCCGTCtgcacgacaacgacaacgagaacgaggaggaggacgacgacaaGCCAAAGGTGAAGCAGGAGCCCACGTATGCCGACGACGAGGATGACGACGAGCAGCAAGTGGAGCTCGACGGCGAGTCGCAAGCGACGCACGCGgaggcagacagagaggcggaggcggaggcagcgAGCGGCGATGCCGACTGCCAGCAGCCGCTGGCGAAGCGACCCAAGATGGAGCTGGTCGACGCCGAGGCCAACACAGTGCACACAGAGCCCAGCAACTACACGTGCTCGACGTGCAAGACCCGCTACACATCCGCGTGGCGCCTCATCCAGCACGTGCAGCACTCGCACGGCGTCAAGATCTACGTCGAGTCGAGCGGTGGCGCCACACTCACCGTGGCCACGCCCGCCGCCCTCAACGCGGCCGCCGTCACGGCAGCCGCGGCGAACGCCCATCACAACCACaatcacaaccacaaccacaaccacaacaacagcagcagctgcggcagcatcAGCCCCAATCGCAGTCTCAGccccacagcagctgcagcagccgctgccgcagtcgccgctgTTGGCGTCCCGCTGCCGTTGCACGCGCTGATGGCCCAGGCCGTTGCCTCGCAGTCCGTGTCGCCGGCAGCCaagcgcagcggcagcagcggcagcagcagcaacaacaacagcagcagcaacagccacaacaacaacaacaacaacagcagcagcagcaactgttcagcaacagccgcagcagcgttggcagccaacacaagtggcagcagcagcagcagcagcagcggtggcaacaacaacagcagcagcagcagcaacagcagccactcgCCCAcacagcaactgctgcagcagcagcaacgcgtgcaacagcagcagcagcaacagcagcagcagcaacaacagcagcagcagcagcagcagagcatgGCCAACGCAATGGCAGCGGGCATGCGGCATCATCCGCTGCTGGCGCCGCCGGAGGCGATGCACGCGAATCCGTTCCAGCTGCTGCGCATGCCGCTGCCACCGGCGCTGGCGCAGAGCAATGTAGTTCCTAGCGTGTCGCCGCTCTTCGGCCGTCCCACGCCCGCCGATCACTATCGCATGGAGCAGCTGGTGAGCGAACAGTTTCGCCACCACGGCTTCAATctggccgccgccgctgccgccgcccagGCGCAGTTCAAcgccagcaaccagcagcagcagcagcagcagcagccagccgTCGGTGGTGTGGCCGTCAATGTTCCTAATCCCGTCGAGCAGCGGCCGCCgtcgagcaacagcagccaacgcGGCTCCGTGCCGCCCGcctcgctgccgccgccctCGCTCAgctcccagcagcagcagcagcagcagcagcagccacagcagcagcaacagcagcagcagcagcagcagcaacaggcggcGTCCGCGGTGAGTCCGGCGTCGGTGAGCCTGGAACCGCAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCACGACAGAAGCAATCGCCGCGCTTTGCGAGCCCCTCGCCCAGCTCGGCAACGCCCACGCCCCGTCCCCACTCCCTGACGCCGCCCGAGAAGCTCGCCGGCGAGAACGGCGCGGGCGCGGGCGCCGCCGCCCCCTCGGCCCCCGCCAACCTCACGCTGCCCAGCACCCCGCGCTCGGCCAGCACGCCGCCTGGAAAAGCAGCCTCCAACGAGGCGGAGACCGAACTGGAGGCCAGCTGCTTCGCCTGCGGCTACTGCGACAAGAAGTTCAGGTTCGAGAACAATCTGATCATCCACCAGCGCACGCACACCGGCGAGAAGCCGTACAAGTGCACCGCCTGCGACTTCGAGTGCTCCCACATCCAGAAGCTGATGAAGCACATGCGTGTGCACCGCAGTCCCGCCGAGGGAcacgacggcggcagcagcaacggcggtGGTGGCAGCGGCGGTGGGGGCAGCGGCGACAACAATCAGGACGGCCACGATGGCGGCAGCAACGCCGACTCGCTGGAGACCAACGAGgccgaccacgacgacgacccCAATCCGGACGAGTCCGACGAGGAGCTGAACGACGAGGAcgtcgatgccgatgccgacggcgacggcgacggcgacggcgacgtcgaggccgagggcgacgacgacgacgacgaggagctgGAGGACTGCGACGATGTCGACTACGAGGCCGAGGACCTGAGCGTCAACAATCGCATCGACGGCAAGAGCCAGAGCCCCAAGACCACCAGCTCCGGCGCCACCTCGCTCGTCGGCGAGCTGATGGACAAGTTCGGGCTCTCGAACATCGCCCAGTACTCCGAGGCCTACAAGCAGGCGCTGCAGGAGTCGGGCCGCAAGGAGGCAGCCGCtgtggccgccgccgccgccgccgccgccgcagccgccgccgtggacaacaacaatcgcgCGGCGGGCGGCGCCGCTGGCGGTGCAGGTGGCGCTGGTGGCGCTGGCGGTGCTGGCGGTGCTGGCGCCGCCGGCCAGCCGCTGAGCGACAAGCTGAACGGTCTGCCAGTGGCTGCGTTGCGGCTGCGCGATGAGTTCGCCAAGAACTGCAACATGTtccagccacagccgcaggaCGGACCCGCGCAGGTGCCGCTCTTCAATCCGTTCCCCAACCCCTTCGAGCTCTCCAAGCGCATGAAGATGGACGGCGGCGACTGGTGGGGCATGTCGGCGCTGCACCGCAACGAGGCGCTGTTCGAGAACCTCAAGCTGAAGCCGCTGGGCCTGGGCGGCGCCAACTCGCTGCTCCAGGGGCCGCTGCTGAAGAAGGAGAGCCGGCAGCGCAACGACACCTGCGAGTTCTGCGGCAAGGTGTTCAAGAACTGCTCCAACCTGACGGTCCACCGACGCAGCCACACCGGCGAGAAGCCGTACAAGTGCGAGCTCTGCTCCTACGCCTGCGCCCAGAGCTCCAAGCTCACCCGCCACATGAAGACGCACGGTCGCACCGGGAAGGACGTCTACCGCTGTCGCTTCTGCGACATGCCCTTCAGCGTGCCCTCCACGCTCGAGAAGCACATGCGCAAGTGCGTCGTCAACCAGGGCAAGgcggccgccgccgcagcgaATGCGGCCAACGCTGTGGCCGCCGCCCaggccgccgctgccgcccagcagctgcaggcggcCGCCGCCcaggcccagcagcagcagcagcagcagcagcaacagctgcccaCGCAGTCGCAGCTGTCGCCTGCCTGCCCCATGGGCGTGGCAGTCGGTTTCCCGCCGCAGTTCGGCTCGATGGGCGGCCACAATCTGTCGCTGCCGGGCAGCGTGAGTGGCGACAACGACTCGAACGCATCGTCCAGCCTGCCAGCGCACTCCATCTCGCTGAAGGAGGAGGCATGA
Protein Sequence: MYNKMLSISEDHGFRSLSHSDSTENDAVAAQDILTCGACQKTFALSDIVRFIQHKVLQCNKENYGQCTTQAPSMDRDADEGRPLSLVNRRPSISAPITNASRKSAPVASTLPPAASGAASAAAAATAAAAATAAAAATAAAAAAAAAATAAAASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKTDGGDGLNLEQSAHIVRSDDCRLHDNDNENEEEDDDKPKVKQEPTYADDEDDDEQQVELDGESQATHAEADREAEAEAASGDADCQQPLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVESSGGATLTVATPAALNAAAVTAAAANAHHNHNHNHNHNHNNSSSCGSISPNRSLSPTAAAAAAAAVAAVGVPLPLHALMAQAVASQSVSPAAKRSGSSGSSSNNNSSSNSHNNNNNNSSSSNCSATAAAALAANTSGSSSSSSSGGNNNSSSSSNSSHSPTQQLLQQQQRVQQQQQQQQQQQQQQQQQQQSMANAMAAGMRHHPLLAPPEAMHANPFQLLRMPLPPALAQSNVVPSVSPLFGRPTPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNASNQQQQQQQQPAVGGVAVNVPNPVEQRPPSSNSSQRGSVPPASLPPPSLSSQQQQQQQQQPQQQQQQQQQQQQQAASAVSPASVSLEPQQMDFYSQRLRQLAGTTSPGAGNIVNSSSPSPRQKQSPRFASPSPSSATPTPRPHSLTPPEKLAGENGAGAGAAAPSAPANLTLPSTPRSASTPPGKAASNEAETELEASCFACGYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPAEGHDGGSSNGGGGSGGGGSGDNNQDGHDGGSNADSLETNEADHDDDPNPDESDEELNDEDVDADADGDGDGDGDVEAEGDDDDDEELEDCDDVDYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAVAAAAAAAAAAAAVDNNNRAAGGAAGGAGGAGGAGGAGGAGAAGQPLSDKLNGLPVAALRLRDEFAKNCNMFQPQPQDGPAQVPLFNPFPNPFELSKRMKMDGGDWWGMSALHRNEALFENLKLKPLGLGGANSLLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAAANAANAVAAAQAAAAAQQLQAAAAQAQQQQQQQQQQLPTQSQLSPACPMGVAVGFPPQFGSMGGHNLSLPGSVSGDNDSNASSSLPAHSISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519433;
90% Identity: -
80% Identity: -