Basic Information

Insect: Drosophila siamana
Gene Symbol: ken1_3
Assembly: GCA_035047445.1
Location: JAWNPP010000151.1:2327681-2330089[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.037 2.2 8.7 5.9 3 23 251 271 249 271 0.96

2 12 0.00091 0.055 13.8 0.5 1 23 277 302 277 302 0.94

3 12 0.0019 0.12 12.7 1.2 1 23 309 334 309 334 0.93

4 12 0.0016 0.099 13.0 4.1 1 23 344 366 344 366 0.96

5 12 0.0019 0.11 12.8 2.2 1 23 373 395 373 395 0.97

6 12 0.0073 0.44 10.9 0.5 1 23 401 423 401 423 0.97

7 12 0.053 3.2 8.2 2.6 1 23 429 452 429 452 0.97

8 12 0.019 1.2 9.6 4.1 1 23 458 480 458 480 0.95

9 12 0.0094 0.57 10.6 2.3 2 23 487 508 486 508 0.96

10 12 0.00019 0.011 15.9 0.8 1 23 605 628 605 628 0.95

11 12 0.00038 0.023 15.0 0.8 1 23 634 656 634 656 0.95

12 12 1e-05 0.0006 19.9 2.3 1 23 662 684 662 684 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.037	2.2	8.7	5.9	3	23	251	271	249	271	0.96
2	12	0.00091	0.055	13.8	0.5	1	23	277	302	277	302	0.94
3	12	0.0019	0.12	12.7	1.2	1	23	309	334	309	334	0.93
4	12	0.0016	0.099	13.0	4.1	1	23	344	366	344	366	0.96
5	12	0.0019	0.11	12.8	2.2	1	23	373	395	373	395	0.97
6	12	0.0073	0.44	10.9	0.5	1	23	401	423	401	423	0.97
7	12	0.053	3.2	8.2	2.6	1	23	429	452	429	452	0.97
8	12	0.019	1.2	9.6	4.1	1	23	458	480	458	480	0.95
9	12	0.0094	0.57	10.6	2.3	2	23	487	508	486	508	0.96
10	12	0.00019	0.011	15.9	0.8	1	23	605	628	605	628	0.95
11	12	0.00038	0.023	15.0	0.8	1	23	634	656	634	656	0.95
12	12	1e-05	0.0006	19.9	2.3	1	23	662	684	662	684	0.98

Sequence Information

Coding Sequence: atgaatgaGGGGAGTGAATACTCCATACACTCGATATGCCGCGTATGCTTAAATCACCTCCGCAACGATGCCGTCTACGATCTTTTCATGGTCCCAGgtttggccaaaaagttgtGTGTCTGCACTTCGTTGTCGGTGGAACAGCACGACGGATTCCCGAAAAACCTTTGCACCTCTTGCTACACACGGCTCAACGATTTGCACGGCTTCCAGAAGATGTGCGTGGATTCAGTGCAAAAGTTCCAGGACATGGTGGCAAACAATTATTTCACTCCAGTTATCTCGGACATCAATCAAATCGACAATGTTGATGTGCTGAATATTGCCCCACCCGAGGGCGAAATGGAGGAAGACCGCATTAACTTTGATCCGTTGCTGAATACGAAAATCGAGATTATAGAGAATGAAGATGACGTCTTTAAAATGCTTGAAGATGTCGATAAAGATGTCGAGGACGTGGACAAAGACAAGGAATCTTCCAGCGAAAGTGAAGCGGAGAACGAGGAAGAGGATGCAGACTTTGATGCCAATAGCAGCGAATCCGAGGACGCAGCGCCTCTATCACGTTTGCGTGGCAACACAAGAGCCAGCAAGGCCAAGACTCGCAaggccgccgctgctgcttcgcGTGATGATGAAGACTCCTCGTCCTCTAGCTCGGAATCGTCGGATGACGATGATAGGCCCAGCTCGAAAGCCAAACGTAAACGCATTCCAGCTGGCGAACGGGATCGTCATCGCCTCATCGACTGTCACATCTGTCATCAGAAGTTCAAGAAGGCTGTGCGCTACGAGGAGCACATGAAACACCACAACGATCTGCTGCCATTCCAGTGCACGGTGGAGTCCTGCAAAAAGGGTTTCACCACCGCCGGCGGGCTGCGCCTGCACATGGATCATGCGCACTCTGAGTTCTCCGAGGTGCACGCCTGCACTTTTGAGGGCTGCGACAAGACCTTTCCACGCTCCGTTTTGCTCACGTTCCATATGAAGAAAGTGCACAAGGTTGCGAAACCTGACGTGAAGCGTCATGCCTGCACCGAATGTGAGAAGGTCTTCCGCTGTCCAACAGCGCTTAAGAAGCACATGTATAAGCACACGGGCGAGGagttgccatttgcctgcGAGATCTGCGGCAAACGTTTCCACATACACAGCGTGCTACGCGATCATCTGCTGCGCCATGCGGGCGTCAAGAACCATGTATGCCCATATTGTGGCGTGGGCAAGACAACCAGGCAGGAGTGGAACAAGCACATCCTGACGCACACGCGCGAGAAGCAGTTCCAGTGTCGTCAGTGCGATCATGCCTCACACAACAAGCAAGCGTTGTCCAATCACGTCAAGGTGGTGCACATGAAGATCAAAAACTTTGCTTGTCAATACTGTGGCAAGACCTTTGGCAAGTCCCATGCCTGCAAGATCCACGAGAGATTGCATACAGGGGAGAACTGCTGCGAGTGCAAGATCTGTGGCAAGATCTTTTTGTTCGAGAAGCGTTTGACCAAGCACTTGCAGATCCACGAGAAACGCGATATTCCGCCACCAGCGGCTGCTGCCACGGCTGTGAAGCCGCCAGGGGAGGGCGATGGTCAAGGCATTGCGAGTGGCagccaggagcagcagcagagtcaTCTGGCCGAGCCAGTGGATGTCAAGCCCCTGCCAGTCATACCACCCAAGCCGAAGCCATCACATCGTGTGGAACGCGTGGATATCTCACAGCTAGCGGGCACCTCGGTCAATCCCATATCGTCTGTCTCCGTGCCGTCGTGGTCACCACAGGTGAACTTCACCAAGAAGGAGGGTCAGCACATTTGTCCGGGCTGCGGTCGTGGCTTCAATCACATTGGCAACATGAAGCTCCACTATAAGATCATACACGAGAAGGTCAAGGATTTCGCATGTCGCTATTGTCCCAAGCGCTTTGCAAAGGCGCAATATTTGCGCAATCATGAGTACATTCATACGGGCGAGAAGCCATTCGAGTGCAAGATCTGTGGCAAACACTTCCGGCAGGAGCAGGTGCTGAAGACGCATCTGAAAGTTCACGACAAACCGCCGAAGCCACCAAAGGAGAAGAAGCCGCCAAAGCCATCGGTTAGCAAGGCCAAGGGATTAAAGGTTGAgctgaacaaaaaacaaccaaaGATTCATGAGGAGTACCAGGATCCGGCCGCAGAGCGGGCAGCGGCCACGGCTGCGCTGTTGGCCCAGCAGATCGAGGAGAATGAGGCGAAGCGAAAACAGGAGGAGGCAAATCGTAAGATACAGGAGGCCGCCTGTGAGCAGCTGAATCGTTTGCAgaagcaaatacaaaacgaaaagGGCTCCTACGACAGCTACTATGGCCAGAAGGCGGAAGCCGAGGGCATCGATCCGGCTGGTCTCAAATTAGATCACGTGTAA
Protein Sequence: MNEGSEYSIHSICRVCLNHLRNDAVYDLFMVPGLAKKLCVCTSLSVEQHDGFPKNLCTSCYTRLNDLHGFQKMCVDSVQKFQDMVANNYFTPVISDINQIDNVDVLNIAPPEGEMEEDRINFDPLLNTKIEIIENEDDVFKMLEDVDKDVEDVDKDKESSSESEAENEEEDADFDANSSESEDAAPLSRLRGNTRASKAKTRKAAAAASRDDEDSSSSSSESSDDDDRPSSKAKRKRIPAGERDRHRLIDCHICHQKFKKAVRYEEHMKHHNDLLPFQCTVESCKKGFTTAGGLRLHMDHAHSEFSEVHACTFEGCDKTFPRSVLLTFHMKKVHKVAKPDVKRHACTECEKVFRCPTALKKHMYKHTGEELPFACEICGKRFHIHSVLRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTREKQFQCRQCDHASHNKQALSNHVKVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLQIHEKRDIPPPAAAATAVKPPGEGDGQGIASGSQEQQQSHLAEPVDVKPLPVIPPKPKPSHRVERVDISQLAGTSVNPISSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKIIHEKVKDFACRYCPKRFAKAQYLRNHEYIHTGEKPFECKICGKHFRQEQVLKTHLKVHDKPPKPPKEKKPPKPSVSKAKGLKVELNKKQPKIHEEYQDPAAERAAATAALLAQQIEENEAKRKQEEANRKIQEAACEQLNRLQKQIQNEKGSYDSYYGQKAEAEGIDPAGLKLDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610124;
90% Identity: iTF_00608675;
80% Identity: -