Basic Information

Insect: Drosophila siamana
Gene Symbol: ken1
Assembly: GCA_035047445.1
Location: JAWNPP010000151.1:2315902-2318220[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0083 0.5 10.8 3.5 2 23 237 258 236 258 0.96

2 12 0.024 1.4 9.3 2.5 1 23 264 289 264 289 0.95

3 12 5.4e-05 0.0033 17.6 1.1 1 23 296 321 296 321 0.97

4 12 0.00028 0.017 15.4 3.9 1 23 329 351 329 351 0.97

5 12 0.00055 0.033 14.5 1.7 2 23 359 380 358 380 0.96

6 12 0.007 0.42 11.0 0.5 1 23 386 408 386 408 0.97

7 12 0.18 11 6.5 7.5 1 23 414 437 414 437 0.97

8 12 0.034 2 8.8 4.4 1 23 443 465 443 465 0.94

9 12 0.0019 0.11 12.8 3.5 2 23 472 493 471 493 0.96

10 12 7.2e-05 0.0043 17.2 0.9 1 23 577 600 577 600 0.96

11 12 0.0015 0.093 13.1 2.7 1 23 606 628 606 628 0.96

12 12 3.1e-05 0.0019 18.4 4.6 3 23 636 656 634 656 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0083	0.5	10.8	3.5	2	23	237	258	236	258	0.96
2	12	0.024	1.4	9.3	2.5	1	23	264	289	264	289	0.95
3	12	5.4e-05	0.0033	17.6	1.1	1	23	296	321	296	321	0.97
4	12	0.00028	0.017	15.4	3.9	1	23	329	351	329	351	0.97
5	12	0.00055	0.033	14.5	1.7	2	23	359	380	358	380	0.96
6	12	0.007	0.42	11.0	0.5	1	23	386	408	386	408	0.97
7	12	0.18	11	6.5	7.5	1	23	414	437	414	437	0.97
8	12	0.034	2	8.8	4.4	1	23	443	465	443	465	0.94
9	12	0.0019	0.11	12.8	3.5	2	23	472	493	471	493	0.96
10	12	7.2e-05	0.0043	17.2	0.9	1	23	577	600	577	600	0.96
11	12	0.0015	0.093	13.1	2.7	1	23	606	628	606	628	0.96
12	12	3.1e-05	0.0019	18.4	4.6	3	23	636	656	634	656	0.98

Sequence Information

Coding Sequence: ATGGATGAGGAGACCACAGTCTCAATACACACGGTTTGCCGCACGTGCCTATCCAACCTAAATCACGTCGCAGCTTTCGATCTCTTTCTTGTCCCTGGCCTAGCCAAAAAGTTGTGCGTCTGCACTTCACTTTCAGTGGAACAGCAGGATGGTTACCCGAAAAACCTCTGCACCACCTGCTATAATCGCCTCAACGATCTGCATGACTTTCAAAAACAGTGTGTGGAATCGGTTGAGAAATTCAAAGATCTGGTAGTGAACAGCTGTTTCCAGACAAATACAGAGgacaattttaatgcaacGAACGTGGTTGAAGAGGATTTGGATCGCAGTACCTTTGACCCGTTGCTGAACAGCAAACTTGAAATTGAGAATGAGGAGGATGTGTTCAAGATGATAGAGGATGTGGATAAGGAGTCAGAGGAAGGCGAGCCACCGGAGCAAGAGCATCCAGAGCAATTCGGGGACTTCGACAATGACGATGATAATGAGGACGAGGACTTCCAGGCAGAGAGCAGTGATTCGCAGGACTCGGTGCCACTATCGCGACGCTTTGCAACTAGAGCAACTAAACAAACCAAGCCCAggaacaaaaagaagaaagagaCGTCGTCTTCAGCCAGCGACACCGAAGACGAAGAAGAGGCTAAACCCAAAAAGAAACGCAAGCGTACGCCAGCCTCTGAGGTGGGCAGTCGTAGTCTACTCCAATGCCACATTTGCCAGCAAAAGTTCAAGATGGCCACGCGTTTCGAGGAGCACATGAAATTCCACAACGACAAGCTACCCTTCCAGTGTCCCGTGGAAAGCTGCAAGAAGGGCTTCACATCCGCCACTGGGCAGCGTCACCACATGGAACACACACATCCCGAGCTGTGCAAGCTGCACAAGTGCACGGTCGAGGGCTGTGGCAAAGAATTCCCACAGACTCGCATGCTTACACAGCATTTGCGCAAGGAGCACAACATTGCCAAGCCTGAGATTCACCCATGTTCCGAGTGTGACAAGGTTTTCCGCTGTCCAACAGCGCTTAAGAAGCACATGTATAAGCACACGGGCGAGGAGCTGCCCATTTCCTGCAATATCTGCAGCAAACGTTTCCACATCAACAGTGAACTTCGGGATCATCTGTTGCGCCATGCCGGCGTTAAGAATCATGTTTGCCCGTATTGTGGCGTGGGCAAAACTACGCGGCAGGAGTGGAACAAGCACATTTTGACTCACACTAAGGAGAAGCAATATCATTGCCGTCATTGCGATCACTCGTCGCATAACAAGCAGGCGCTATCGAATCACATCAAGGTGGTGCACATGAAGATCAAGAACTTTGCTTGTCAATACTGTGGCAAGACCTTTGGCAAGTCGCATGCATGCAAGCTGCACGAGAGATTGCACACGGGGGAGAATTGTTGCGAGTGCAAAATCTGTGGCAAAGTCTTTTTATTCGAGAAGCGTTTGACCAAACATCTGAAGACGCATGAAAAACGCGACACTCCTGCGACAGCTGGCacggcaaaacaaaaaacagaggCGGATGCCGCGAAGGAGGAGAGCCAAGAGACAGTGGAAGTAAAGAATGTACCTCCGCTTCCTACCAAGCCAAAGACATCGAATCGCATCGAGCGTGTGGACATTTCCCAATTGGCTGGCACCGCTGTCAATCCCATTCCGTCGGTCTCGGTGCCATCGTGGTCGCCGCAAGTCAATTTCACCAAAAAGGAGGGTCAACACATTTGTCCTGGCTGTGGCAAGGGCTTCAATCACATTGGCAACATGAAACTCCACTATAAGGTAGTGCACGAAAAGATCAAGGATTTTGCTTGCCGCTATTGCCCTAAGCGCTTTGGCAAGGCGCAATATCTGCAGCACCATGAATATACACACACTGGTGAGAAGCCGTATGGCTGCAAAATCTGCGACAGACATTTCAGTCATGGCTCGTCTTTGAGGAAGCACATGCAGTCGCATAACAAGCCGCCCAAGGAGCCGAAGCCGCCCAAACCACAACCCAAGTCCACAGAGCCGCCGACGCCGCGTGTAAAACTGAATCGGCAACCAACCAAGAACTATGAGCAGTATCAAGATCCAGCTGCCGAGCGAGCGGCTGCAAGAGCTGAACTCATCGCCCAACAACACGATGAACATGAGGTGAAGCGCAAGGCAGCGGAGAAGATACGCAAGATTCAGGAGGCGGCTTGTGAGCAGTTGCAagagttgcagcagcaacaactcatCGACAAGATCTCTAGCGACAGTTTCACTGAAATAAACTTTGAAGACGTGCAGCGAGTTGATGCTCTTAAAGAAGATCCCGTTTAA
Protein Sequence: MDEETTVSIHTVCRTCLSNLNHVAAFDLFLVPGLAKKLCVCTSLSVEQQDGYPKNLCTTCYNRLNDLHDFQKQCVESVEKFKDLVVNSCFQTNTEDNFNATNVVEEDLDRSTFDPLLNSKLEIENEEDVFKMIEDVDKESEEGEPPEQEHPEQFGDFDNDDDNEDEDFQAESSDSQDSVPLSRRFATRATKQTKPRNKKKKETSSSASDTEDEEEAKPKKKRKRTPASEVGSRSLLQCHICQQKFKMATRFEEHMKFHNDKLPFQCPVESCKKGFTSATGQRHHMEHTHPELCKLHKCTVEGCGKEFPQTRMLTQHLRKEHNIAKPEIHPCSECDKVFRCPTALKKHMYKHTGEELPISCNICSKRFHINSELRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKQYHCRHCDHSSHNKQALSNHIKVVHMKIKNFACQYCGKTFGKSHACKLHERLHTGENCCECKICGKVFLFEKRLTKHLKTHEKRDTPATAGTAKQKTEADAAKEESQETVEVKNVPPLPTKPKTSNRIERVDISQLAGTAVNPIPSVSVPSWSPQVNFTKKEGQHICPGCGKGFNHIGNMKLHYKVVHEKIKDFACRYCPKRFGKAQYLQHHEYTHTGEKPYGCKICDRHFSHGSSLRKHMQSHNKPPKEPKPPKPQPKSTEPPTPRVKLNRQPTKNYEQYQDPAAERAAARAELIAQQHDEHEVKRKAAEKIRKIQEAACEQLQELQQQQLIDKISSDSFTEINFEDVQRVDALKEDPV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00579466;
90% Identity: iTF_00589750;
80% Identity: -