Basic Information

Insect: Drosophila siamana
Gene Symbol: -
Assembly: GCA_035047445.1
Location: JAWNPP010000014.1:1668795-1672854[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.1 6.1 7.4 5.8 2 23 348 370 347 370 0.96

2 17 0.7 42 4.7 0.4 1 23 377 402 377 402 0.92

3 17 0.024 1.4 9.3 1.8 2 23 413 434 413 434 0.93

4 17 5.8 3.5e+02 1.8 3.0 2 17 445 460 444 471 0.75

5 17 0.54 33 5.0 0.3 3 14 504 515 502 524 0.73

6 17 0.00062 0.037 14.3 1.2 1 23 532 555 532 555 0.97

7 17 0.00015 0.0093 16.2 0.3 2 23 560 581 559 581 0.97

8 17 0.00057 0.034 14.4 0.2 1 22 629 650 629 653 0.90

9 17 0.052 3.1 8.2 4.9 1 21 658 678 658 679 0.95

10 17 0.02 1.2 9.6 0.6 1 23 698 723 698 723 0.96

11 17 0.037 2.2 8.7 1.6 2 23 739 761 738 761 0.93

12 17 0.0084 0.51 10.7 0.9 2 23 767 789 766 789 0.93

13 17 0.0081 0.49 10.8 0.6 2 23 793 815 792 815 0.96

14 17 0.00011 0.0064 16.7 1.6 1 23 821 843 821 843 0.97

15 17 0.0046 0.28 11.6 0.5 1 23 847 870 847 870 0.93

16 17 1.5e-05 0.00088 19.4 1.2 1 23 876 899 876 899 0.97

17 17 0.0035 0.21 11.9 0.1 5 23 912 931 904 931 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.1	6.1	7.4	5.8	2	23	348	370	347	370	0.96
2	17	0.7	42	4.7	0.4	1	23	377	402	377	402	0.92
3	17	0.024	1.4	9.3	1.8	2	23	413	434	413	434	0.93
4	17	5.8	3.5e+02	1.8	3.0	2	17	445	460	444	471	0.75
5	17	0.54	33	5.0	0.3	3	14	504	515	502	524	0.73
6	17	0.00062	0.037	14.3	1.2	1	23	532	555	532	555	0.97
7	17	0.00015	0.0093	16.2	0.3	2	23	560	581	559	581	0.97
8	17	0.00057	0.034	14.4	0.2	1	22	629	650	629	653	0.90
9	17	0.052	3.1	8.2	4.9	1	21	658	678	658	679	0.95
10	17	0.02	1.2	9.6	0.6	1	23	698	723	698	723	0.96
11	17	0.037	2.2	8.7	1.6	2	23	739	761	738	761	0.93
12	17	0.0084	0.51	10.7	0.9	2	23	767	789	766	789	0.93
13	17	0.0081	0.49	10.8	0.6	2	23	793	815	792	815	0.96
14	17	0.00011	0.0064	16.7	1.6	1	23	821	843	821	843	0.97
15	17	0.0046	0.28	11.6	0.5	1	23	847	870	847	870	0.93
16	17	1.5e-05	0.00088	19.4	1.2	1	23	876	899	876	899	0.97
17	17	0.0035	0.21	11.9	0.1	5	23	912	931	904	931	0.90

Sequence Information

Coding Sequence: ATGTCGAAagcaaaaactgaaaatgggCCTAGCTGCCTGCATTGCAGAGTGCACGATTCAAAACAGCCATTCCACGAGATCTTCGATGCAGTGGGTATTGAAATTGGATTGCCCGATTTACTCGAACAGTATTTCCAAATAAGTGTGAAACCCGAACCAAAAAAACAGCAATTGTTGTGCGTGGAGTGCGTAAATACGCTGATTCGATTCTTTGACATTGACGAACTGCAGCGGGAGCAGGATGCGGCAAATGCGGCCAAGAAAGGTAAGCAAGTTGCTAAGACTACCAAAGGCGGCGCCAAAACCGAGACTGCAGCAGCCACTCCCGCTAAAGTTGAAGCGACGCCTGCAAGGAAACAGACGCCGCCGGCGGTCAAAGCAAAAGCCGAGCCCAAAAAGGAAGCAACAAAGTTACCAGTCAAGCCAAAGcctgctcctgttgctgttgctgcaaagCCAGATGAGCCCGTTGCTGTGCGCATTAGCAAAGGCAAAACATTGACTGTGACACCACTCAAGGCTAAATCCAAAACTAGCCAAGCGGCTTGTGTTAAGTTGGAGGCCAAACGCAGTAATTCCAAGGAAGCTAGTTCTGCAGATCAGGAGCAGATAGGCGCGCTGCTGCGTGACATACTCGGTGAAGAGAAGACGGCATCGGCTGACAAATTCGTCGAAGCAgctgaaacaatgaaacaactGGAAAGCCAAGCAAACGAGCAAGAAAAACAGCTGGAGAACGACGAAGAGGAAATCGCCGcggaggagcagctgctgaagcAACAGGAGAACACAGATGAATTGGAGTTTCTGCTTGAGGGTGATTCCTCCGATATGGATGTATCCCAATTTAAGTCAAATAAGCAGTCATCAAATAATACAGCTCGATCACaaaacgaaagcgaaagcgagaaTGAATCTCTGAAAGTTGAGCCTTTTAACTTTGTCCTAATCAAGGAATCTGACGATGTTGGAGATCTGTATGAATATCTAACGACTGTGGTGAAGACCTGCTTTGAGACCTTGTCTTTTGAGTGGGCCACCGTTTGTCAGCATTGCTCGATGAAGTTCAACAAATTCGAGACTCTGTTGAGCCACATGCTCAAATGCCATCAGCTGCCGGATCAACAGTTTAAGTGTCCCATTGGCGGCTGCCACAAGAAGCTGCAAGGGCGCAAATTCTTGGCTATGCACTTGGTTGTGCTCCACGCGCCGGTGGCAGAaaTACCGATTTATGGCAGCTGCCCAGAGTGCAACCTGACGTTCTCGAATATATTGCAATACAATAAGCACTCCTGCGCCCATGTGATCAAAAAGCGCCGTGGCATACGTTTATACTGCGAAATGTGTGGTCTGGAGTTTCCTTCCTGGAAGCGCTTCAACTTTCACAATCAATTCCATTTGGAGCGGCATCGGCCGCGCGCCTGTTTCGTGTGCGATTATGCGGATAATAACATCGATGATCTGTTCCAGCATTTGCACTATTCCCATGAACCCGAGGGCACGCTCTTTTGCGATCTCTGTGATCGCACATTTCGTGATGGCGCCATCTTTGCGGAGCACAACAAGTCCCATGCGAATGTCACCAGCACCACTTTCAGCTGCAGCGAGTGCAACGCTCACTTTGAGACGCGCGGTCGCCTTAACGGTCACATGcGCATCACACATGGTACTGTCATCAGCTGTGAGCTCTGCAATCGCGAGTTTGCCACCGAAGCCAGCTACAATATTCACATGAAGAAGCATCTGATCATCGAACGCGAGGTGCATGTGTGCAATAGTTGCGGTTTGCTCAGCGAGAGTCACGAGAAGATGGTGGCGCACGTTGAAAATGAGGATTTACCTTGCTTTGGCGTCGACACGTATGTGGAGCTGCTGAGAGATGCCTATATCTGTGAATACTGCTCGGCTTACTTTAATTCGAAGGCTAATTTGCGTGCTCACCGCGATTCTGGCGTGCATAAGAATGGGCTTTTCTGTTGCCATCCGTGTGGCAAGGAGTTTAACGACATGAAATTGTATCGTCATCACATGCGCAACTTTCAGCTACAGCGCGCGGATGTGGCACATCGCAAGCTAGAGATTTGTCTGTACTTCATGTGCGACTATGAGGATTGCTTGGAGTCGTACATTAGTTGGAATTCGCTGTACACGCACAAGCGTCGCACTCACGAAGTGGCCGAGAAGCTGGATGCAAAGTCAAAGGTAGATGAATGGATTTGTCAATTCTGTCAGAAGGAGTGCCGCTCCAAAATGTCGCTCTCAGTACACGTGGCACGCAGTCACAACAACAaCAATGTCACTTGCAAGCTGTGCAATGCGTCGTATAAGAATGACGAGGCGCTGAAGAAGCATCACGCTTACTGGCACGAGCCCATGGAGTGCTCGTTGTGCTTCAAGATTGTGAAGAATCGTCGCAACTTTGACACGCACATGAATGTGGTGCACTCAGACAACAAACGCTATGCCTGCAGTGTCTGCCAAAAGGGATTCTATCACAAGAGCGAAATGGAGGCGCACAAGCGACTGCATAACCAATCCTATAGATGTGAGCAATGCAGCTTCGTCACAAAGAACAAGAAGTCACTGGCGGTTCATGTGCTTGGCCAGCATTACAGGCGCTTTGCCTTCGAGTGCAAGCAGTGCAGCAAACGCTTTGGGCGCCAGCAGGGCTTAACCAACCACATGTTGCGAGTACATGCCTCTAAGAACACATGTCGCGATTTCCTGGAAGGCGGCTGCAACAGAGCCTTCAACACATTGGCACAGCTGAGTGCTCATGTGCGCAAGgtgcacaacagcagcatcaatgTGAACGACGAGGTTGACGATGAGCCCGTGGAACTGGAGCCAGAGGAGGAGGAACAGGAagagcaggaggagcagctgAAAAACAAGTCGAAGCGAGAGAACACGACAGCACCTACTCAACAGCAAAAGAAGCGTTGCGTACGCCTCACTAATGACACACAGATTGAATTCATTAACGCCGAAGCCGACGAGGAGCAGAAGAGCGCTGCGGAGTCAGATACTTTAGAGGAATTGCAGGAGACCAAAGCCAAACCCTTGCCCGTAAAGCGAAAGAAAAGACAATGTTAA
Protein Sequence: MSKAKTENGPSCLHCRVHDSKQPFHEIFDAVGIEIGLPDLLEQYFQISVKPEPKKQQLLCVECVNTLIRFFDIDELQREQDAANAAKKGKQVAKTTKGGAKTETAAATPAKVEATPARKQTPPAVKAKAEPKKEATKLPVKPKPAPVAVAAKPDEPVAVRISKGKTLTVTPLKAKSKTSQAACVKLEAKRSNSKEASSADQEQIGALLRDILGEEKTASADKFVEAAETMKQLESQANEQEKQLENDEEEIAAEEQLLKQQENTDELEFLLEGDSSDMDVSQFKSNKQSSNNTARSQNESESENESLKVEPFNFVLIKESDDVGDLYEYLTTVVKTCFETLSFEWATVCQHCSMKFNKFETLLSHMLKCHQLPDQQFKCPIGGCHKKLQGRKFLAMHLVVLHAPVAEIPIYGSCPECNLTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCDYADNNIDDLFQHLHYSHEPEGTLFCDLCDRTFRDGAIFAEHNKSHANVTSTTFSCSECNAHFETRGRLNGHMRITHGTVISCELCNREFATEASYNIHMKKHLIIEREVHVCNSCGLLSESHEKMVAHVENEDLPCFGVDTYVELLRDAYICEYCSAYFNSKANLRAHRDSGVHKNGLFCCHPCGKEFNDMKLYRHHMRNFQLQRADVAHRKLEICLYFMCDYEDCLESYISWNSLYTHKRRTHEVAEKLDAKSKVDEWICQFCQKECRSKMSLSVHVARSHNNNNVTCKLCNASYKNDEALKKHHAYWHEPMECSLCFKIVKNRRNFDTHMNVVHSDNKRYACSVCQKGFYHKSEMEAHKRLHNQSYRCEQCSFVTKNKKSLAVHVLGQHYRRFAFECKQCSKRFGRQQGLTNHMLRVHASKNTCRDFLEGGCNRAFNTLAQLSAHVRKVHNSSINVNDEVDDEPVELEPEEEEQEEQEEQLKNKSKRENTTAPTQQQKKRCVRLTNDTQIEFINAEADEEQKSAAESDTLEELQETKAKPLPVKRKKRQC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00589718;
90% Identity: iTF_00589718;
80% Identity: -