Dsia010755.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila siamana
Gene Symbol
RREB1
Assembly
GCA_035047445.1
Location
JAWNPP010000078.1:17868725-17876023[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.0059 0.36 11.2 0.6 1 21 263 283 263 285 0.96
2 13 0.00034 0.021 15.1 0.2 1 23 295 317 295 317 0.98
3 13 8.2e-05 0.0049 17.1 7.3 1 23 323 345 323 345 0.98
4 13 0.2 12 6.4 2.5 2 20 570 588 570 590 0.93
5 13 0.009 0.54 10.7 0.1 1 23 763 785 763 785 0.97
6 13 1.3e-05 0.00076 19.6 0.7 1 23 795 817 795 817 0.99
7 13 0.00084 0.051 13.9 2.0 1 23 823 846 823 846 0.97
8 13 0.003 0.18 12.1 2.0 1 23 1120 1143 1120 1143 0.95
9 13 8.8e-05 0.0053 17.0 0.3 2 23 1491 1512 1490 1512 0.97
10 13 0.15 8.9 6.8 6.3 1 23 1518 1541 1518 1541 0.97
11 13 4.7 2.8e+02 2.1 3.7 1 23 1672 1695 1672 1695 0.78
12 13 0.0086 0.52 10.7 0.5 3 23 1758 1778 1756 1778 0.96
13 13 0.0014 0.086 13.2 4.8 1 23 1784 1806 1784 1806 0.99

Sequence Information

Coding Sequence
aTGCTggccacacaacaacagcaacaacaaccacaacacacggcgacagcagcgacagcaacggcaacagcgacagcgacaacagctgcCCACAGCGACGATGGGCAGAGCTTGGATGgcgagcgacagcgacgcgaTTCGACCACCTCAGAGTCATCGCTGGAGCATCTCGATCTGGGACGCACACCAAAgaagctgagcagcagcagcggcgcaccgcagccgacgtcgacgccacACGagacgtcagcgtcagcgtcagcgtcgacgtcgcgcAAGCGCAagctgcgacagcaacaacagcagcagcagcagcatcaacagttGTCCGACGAAGacgaacagcagccgcagccgcagcaacagttggAGACAACAgcgcagcgactgcgacacaAGCAGCGACGCAACGtcgccgccagcgccagcaTCGTGGTCGACTACAGCGGCGACGCGAGTTCGCTGCGCAAAAAGTTTCGCCTCAATCGCAGCAGCGCCAACCTCAACGTCAACGGCGACCTCTCCGAATCCGGCTTCGTCGACGGCAGCGCCAACAGCGGCTATttgctcagcagcagcagcggcagcggcagcggcaacagcagcgcagtcaacgccaccgtcgccgccgccgccgccgccgctgcggcagcagcagcagttgcagcgcagcaacagcaacagcatcagatGTCGTCGAGCAGCTCGGGCGGCTCCTCGCCCCAGGGCGGCCTCAGCTTGTCGAGCGCCGAGTCTGGCATCGGAGCCGGTGATGAGCACATGAAGTATGTGTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCGAAGGTGCTGTCGTCGGCCTCGTCGCTGGATCGTCACGTGCTGGTGCACACCGGAGAGCGGCCGTTCAACTGCCGCTACTGCCACCTGACGTTCACCACCAACGGCAACATGCATCGTCACATGCGCACGCAcaagcagcatcagcagcagtcgcaacactcgcagtcgcagtcgcagtcgcagcagcagcagcaacaatcgcagtcgcagtcgcagcagcgacgtcagcagcaggcggcgacAGCGGCGGGTGCCGCACAGCtgcaggcggcggcagcggcagcgacagcgacgtcggcaGCGGCGGGACGAACGGAGAGCTATGAGAGCGATGCCAGCTGCTCGACGGATCTGTCGAGTGCGCAGAGTcagagcagccacagcagccgcaacagcagccaacgctccctcaacaacaacaacagcaagttgagcaacaacaacaacaacaacaacaacgtggagctggagctgaagagCCACAAGAGtcacaacatgaacaacaacaacatcgttGAGGACGAggtgcagcaggagcaggaggaggacggcgacggcgacggcgacgacgacggcgatgagcTGGAGAGGCAGACGCAGCCAGAGGCGGACGACAGCGAGTCGGAGGTGACACAGGTCATCACCAGCACCCCCGACGTCGCCACGTTGCTGGCCAGCTCCTCACGCTCCGGCGGCACAACGCCCAAccagctgctcagctgcccCGCCTGCCCGGCCGACGACTTCGAGACGCTGCCGGCGCTGTGCCAGCATCTGGACGCCCAGCACGCCGACATACCGGCCAAGTGCCGGGAGTGCGACGTCATCTTCGCCAGCCATCGCCAGCTGCAGACGCACAGTTGTCGCCTGcagatgctgccgctgctgggcGCCAGTTCGTCGCCGCTGCATCAGCACAAGCGGGagcgcgacgacgacgacgacgacgaggacgacgaggacgagaacGAGGAGGACGATGTGGGGGACATGGAGGACGAGGATGTGGAGGGGCAGCATGcggcgcagcggcagcagcagagcgaacGCGACGACTTCTTTCACCAGCTGTACCTGAAGGGCAAGTCAAGCGGCGTCCTGCTGCCGTCGCCCATCAAACACGAGCCGGCGAcgagcaacaaccacagccacagccacaaccacagccagcagagcaacaacgacagtCGCCAGGATCTGGCCGACATACAGAGCATACTGAACATgaccagctccagctgcaccTCCAGCTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAGTACAGCCTCGACGGTCGCGACGGCGACGAGGAGGCCCAGGACGCGTTCACCAGCGAGTTCAGGCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTGTGCAGCGCCGTCTTTCCCAATCTGCGCGCCCTCAAGGGCCACAATCGCGTCCATCTCGCCGCCGTCGGCGCCGCCGGTCCCTTCAGGTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCGGCGCTGGTGCGTCACATGCGCACCCACAACGGCGATCGGCCCTACGAATGCGCCGTCTGCAATTACGCCTTCACCACGAAGGCCAACTGTGAGCGGCATCTGCGCAATCGGCACGGCAAGACGAGTCGCGAGGAGGTGAAGCGTGCCATACTCTATCATCCCGCCGAGGACGCCAGCTGTGAGGAGGCCAAGTCCGCGGCGGGCTGTGCCCAAGAGCTGGCGGAGCTCAGCTTTCGCTCtgcgtcgccgccgccgccgccgccgccgacgtcgtcgtcgtcgttgttggcaGCCACTGAGCCGCTGAGCGGCAGCTCACAGCTGAAGCACATGCTGCTGGcggagagcagcagcggcagcgtcaacTCGCCCAAGATCCAGGTGAAGAGTCTCGATCAGCTGGTGGAGAAGCCGCAGCTCGATCTCAGCATGGATGTGCTGGACTTGAGCAAGAAGCCGCTGCTCGCCCAggagctgctcgagcagcGCGAGCgcgagcgggagcgggagcgggagcgggaaagggaacgcgaacgcgagcacgaattgttgctgcaacagcagcagcagcagcaacaacaggcgcaacagcaacagcagcaggcgcaacaAATGTTTGGCGCCGGCGACGCTGCCACGCAGTACATGCAACAGTTGTTTCGCAATCTAATGTTCCAGCAGACGCCCGGTTTCCCCTTCTACGGCTTCATGGGGCTTCCcaacgccgccgtcgccgccgccgccgtcgcagcGCCCGAAAAGTCCACgacgtcgtcggcgtcgtcgtcggcagcagcagcagctgcgacgactgcgctgccgctgcccaaTGTGGGCGTGCCGATGCCCGCCGGCGGCCCCGTCAAGATGGTCATCAAGAACGGCGTCCTGATGcccaagcagaagcagcgacgCTACCGCACCGAGCGTCCCTTTGCCTGCGAACACTGCTCGGCCCGCTTCACGCTGCGCTCCAACATGGAGCGGCATGTGAAGCAACAGCATCCGCAGTTCTATGCGCAGCGTCAGCGCAGCGGTCATCACGTGATGCGCGGCCGTGCGGCCTCCTCcagcgctgcagcagccgcagcggcggcggcggcggcggcgacggcggcagcagcggcagcagcagcagcagctgccatgtcgagtcagcagcagcacagccagCAGTCGCACGCTCACATCTCGGACGAGGTGAAGTACGCGATACTGGCGCAGCAGCTGAAGGCGCGCAAGGACACCGATCTGCTGCAGCAAGCGCTGGCGCATGGCTCGAGCAGCGTTGTGGCCAATCCGCTGCTGCACTTTGGCTACAAGCCGGCTGCAGGCAACGGCGTCGTGCCgcagcatgtggcaggcaACGGCTGTGCGGcagtcgacgacgatgagccGCCCAAGCTGATCatcgacgaggacgacgacgacgagggcgagggcgagggcgacgGGGACGAGGACttcgaggaggaggaggacgaggagctggacgaggaggagccgcagcagcagctgcagcagccgacgacgacgccggAGCTGGAGCAGTCGACGCCGCGCAGCTCGACGCCCATCGAGGCGGCCAAGAAGGTGGCCGAGACCATCCTGGAGCAGGCCATCAAGGCGGGCAAGTGCAGCGAGTCGCTCGCCGAGCCCAAGCCCAAGGCGAagccagcagcgacgccagcggcgacgccagcagcgacggcgacgccgacgcccATGAAGACGCTCATCGCGCAGGCCGAGTCCGTGGCCAAGTCGCTCAAGGATGTGGCCAGCTCGCCGTTCAAGGATGAATCTCAGTCCGATCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCCACCAGCAATCAGGTGTCGTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGACTCGTCGCCTCCGGCAGCGCCAGCGAGAGCAACAACTCCGGCACCGAGGAcgtcaccagcagcagcagcaacgagccGAAGAAGAAGTCCGCCTACAGCCTGGCCCCCAATCGCGTCAGCTGCCCCTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTGACACACACCGGGCAGAAGCCGTTCAAGTGCTCGCACTGCCCGCTGCTGTTCACCACCAAGAGCAACTGCGACCGGCATCTGTTGCGCAAGCACGGCAACGTCGAGAGCGCCATGAGCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATCCCGGTGCCCAAGTCCGTCGAGGAGATCGAGCTGGAGGAGCAGCGTCGCCGTCGCGCCGCCGAGGCGGAGCTGGAGCGGGAGCGTGAACGGGAGCGGGAGCGTGAACGGGAGctggagcgggagcgggagcgggagcgggaacgggagcgggagcggcgccagctggagcaggagcgggagcagcagcagctcatacagcagctggcagcggcCGCACAAAtggccgcagccgccgccgccgccgcagcgctcaacaacaacaacaacaacagcagcagcgggtcGAGCGAGGCGGCGGCCGCGGGGGAGGCGCAGGGCAGCGATCTGCCCTACAAGTGCCATCTGTGCGAGTATTCGTTTGGCGAGCGCCTGCAGTGTCTCGACCACatcaagcagcagcatgcGCAGGAgtttgcgctgctgctcgccaAGGGCGCCATCGAAACGGAGggcgaacagcagcagttgccaccACCGCCCCCGCCGTCGACAGCGGCGTCGGACGAAGAGGGCGGCACAGGTGGCGGCCCAGGCGGCGCAAGCGGCACACGCGGCAAGTATCCGGACTACAGCAATCGCAAGGTGATCTGCGCCTTCTGCGTGCGTCGCTTCTGGTCCACCGAGGATCTGCGGCGTCACATGCGCACCCACTCGGGTGAGCGGCCGTTTCAGTGCGACATCTGTCTGCGCAAGTTCACGCTGAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGCGGACGCAGCCACAATGGGGAGCAGGGCGCTCACTCCGATTGCTCCGACGACGAGCAGGCGCCGCTCAGCAGTCCGCCCAGCACGCCGACGCCCAGCGTCAACTCCATggccaccagcaacaacaacaacaacaacaacaacaacacttgccacaacaacaacaacaacaacaccactaacaacaacaacaacaacaatggcaaggCGAGTCTGCGTCTGCCGAAGCTGCACGAGCTGCTGGACAAGGCCAGCGAGTGGCGCGACAGCCACTTGGGCGAGCACAAGGAGAATCTGGGCGAGGCCAGCGCCAAATCATCGTCCGCCGCCGGCCAGGCCGCCGTCGCTGTGGCAGCCGCCGCGGCGGCGAGCAGCGAACTGATGTGCGACCTGCTGGGCCTCAGCGATCAGGGGATACTCAACAAGCTGCTCTCGTCGCCCGACGAGGCCGCCAAGCTGCTGGGCGTTGAGAAGTGA
Protein Sequence
MLATQQQQQQPQHTATAATATATATATTAAHSDDGQSLDGERQRRDSTTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHETSASASASTSRKRKLRQQQQQQQQHQQLSDEDEQQPQPQQQLETTAQRLRHKQRRNVAASASIVVDYSGDASSLRKKFRLNRSSANLNVNGDLSESGFVDGSANSGYLLSSSSGSGSGNSSAVNATVAAAAAAAAAAAAVAAQQQQQHQMSSSSSGGSSPQGGLSLSSAESGIGAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQQQSQHSQSQSQSQQQQQQSQSQSQQRRQQQAATAAGAAQLQAAAAAATATSAAAGRTESYESDASCSTDLSSAQSQSSHSSRNSSQRSLNNNNSKLSNNNNNNNNVELELKSHKSHNMNNNNIVEDEVQQEQEEDGDGDGDDDGDELERQTQPEADDSESEVTQVITSTPDVATLLASSSRSGGTTPNQLLSCPACPADDFETLPALCQHLDAQHADIPAKCRECDVIFASHRQLQTHSCRLQMLPLLGASSSPLHQHKRERDDDDDDEDDEDENEEDDVGDMEDEDVEGQHAAQRQQQSERDDFFHQLYLKGKSSGVLLPSPIKHEPATSNNHSHSHNHSQQSNNDSRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGDEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLAAVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAILYHPAEDASCEEAKSAAGCAQELAELSFRSASPPPPPPPTSSSSLLAATEPLSGSSQLKHMLLAESSSGSVNSPKIQVKSLDQLVEKPQLDLSMDVLDLSKKPLLAQELLEQREREREREREREREREREHELLLQQQQQQQQQAQQQQQQAQQMFGAGDAATQYMQQLFRNLMFQQTPGFPFYGFMGLPNAAVAAAAVAAPEKSTTSSASSSAAAAAATTALPLPNVGVPMPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAASSSAAAAAAAAAAAATAAAAAAAAAAAMSSQQQHSQQSHAHISDEVKYAILAQQLKARKDTDLLQQALAHGSSSVVANPLLHFGYKPAAGNGVVPQHVAGNGCAAVDDDEPPKLIIDEDDDDEGEGEGDGDEDFEEEEDEELDEEEPQQQLQQPTTTPELEQSTPRSSTPIEAAKKVAETILEQAIKAGKCSESLAEPKPKAKPAATPAATPAATATPTPMKTLIAQAESVAKSLKDVASSPFKDESQSDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRRAAEAELERERERERERERELERERERERERERERRQLEQEREQQQLIQQLAAAAQMAAAAAAAAALNNNNNNSSSGSSEAAAAGEAQGSDLPYKCHLCEYSFGERLQCLDHIKQQHAQEFALLLAKGAIETEGEQQQLPPPPPPSTAASDEEGGTGGGPGGASGTRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRSHNGEQGAHSDCSDDEQAPLSSPPSTPTPSVNSMATSNNNNNNNNNTCHNNNNNNTTNNNNNNNGKASLRLPKLHELLDKASEWRDSHLGEHKENLGEASAKSSSAAGQAAVAVAAAAAASSELMCDLLGLSDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-