Basic Information

Insect: Drosophila siamana
Gene Symbol: -
Assembly: GCA_035047445.1
Location: JAWNPP010000151.1:2321627-2323798[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 3.5e-05 0.0021 18.2 4.1 2 23 210 231 209 231 0.96

2 11 0.013 0.77 10.2 4.3 1 23 237 262 237 262 0.94

3 11 0.00024 0.014 15.6 0.3 1 23 269 294 269 294 0.95

4 11 0.0013 0.076 13.3 3.7 1 23 302 324 302 324 0.97

5 11 5.2e-05 0.0031 17.7 0.7 3 23 333 353 331 353 0.98

6 11 0.0044 0.27 11.6 0.6 1 23 359 381 359 381 0.98

7 11 0.0021 0.13 12.6 0.9 1 23 416 438 416 438 0.95

8 11 0.0011 0.067 13.5 0.9 1 23 444 466 444 466 0.97

9 11 9.2e-06 0.00055 20.1 0.3 3 23 528 549 527 549 0.97

10 11 0.00096 0.058 13.7 1.2 1 23 555 577 555 577 0.97

11 11 0.0005 0.03 14.6 2.7 1 23 583 605 583 606 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	3.5e-05	0.0021	18.2	4.1	2	23	210	231	209	231	0.96
2	11	0.013	0.77	10.2	4.3	1	23	237	262	237	262	0.94
3	11	0.00024	0.014	15.6	0.3	1	23	269	294	269	294	0.95
4	11	0.0013	0.076	13.3	3.7	1	23	302	324	302	324	0.97
5	11	5.2e-05	0.0031	17.7	0.7	3	23	333	353	331	353	0.98
6	11	0.0044	0.27	11.6	0.6	1	23	359	381	359	381	0.98
7	11	0.0021	0.13	12.6	0.9	1	23	416	438	416	438	0.95
8	11	0.0011	0.067	13.5	0.9	1	23	444	466	444	466	0.97
9	11	9.2e-06	0.00055	20.1	0.3	3	23	528	549	527	549	0.97
10	11	0.00096	0.058	13.7	1.2	1	23	555	577	555	577	0.97
11	11	0.0005	0.03	14.6	2.7	1	23	583	605	583	606	0.96

Sequence Information

Coding Sequence: atgagtgAGGAGAATTTGGGCATAGCCCAAAAATTCTGTCGCACGTGTATAAAAGAGCTGAGCCAAGATGACGCCTTCGATATATTCATTGTGCCCGGCCTGGCAAagaaattgtgtgtgtgcacttcgTTGTCCGTGGAGCATCATGATGGATTCCCCACAAACATCTGTCCGGCATGTTACCGCCGCCTTAACGACTTGCACGACTTTCAAGAACAATGCGTAAACTCTATGCAAAAGTTCAAGGAGATGTTGGTCACCAGTTGCAATTTCAGCGTGGTCAATGCAGCTGGTGACCAGGAGGCTGAGGTGTCTTTTGAAGAGCAGGAGCACACGCACTTCGATCCATTGCTCAATGGcaaaatagaaattgaataCGAGCAAGATGTGTTGAAAATGATAGAAGAGGTCGATAAAGAGTCGGTGGAAGATAAAGTGGAAAGGCAGCAATCAATCGACAGCGTCGACAACAATGAGAGTGACGATAATGAAGGAATTGATTTCGAGGGGGATAGCAGCGACTCTGATTTCACGTTGCCGCTTTCGAGTCTAAAAaggataacaaaaaaaagcaagggGGCTGCTCAAGTTACCACAGAATCAAAGCCGAAACCACAACGGATGCTTGAGTGTCACATTTGCACACAGAAGTTCAAGAAATCATCTAACTATCAGGAGCACATGAAACAGCACGACGATCAATTACCCCACCAGTGCCCTGTGGAGTCATGTAAGACAGGCTTTACCACACCGCATGGATTGCGACATCACATCGAACACATGCACACGGAACTCTGCCAAATGTTTGCATGCACCGTGGAAGGATGCAACAAGCAATTTCCTATCAAACGTTCGCTAACTAGACACTTGAGAATCATGCACAACATGGCCAAGCCTGAGACTCATCCGTGCACGGAATGCGACAAGATCTTTCGGTGTCCCATGGCGCTTAAAAAGCACATGTACAAACACACGGGTGAGGAGATGCCATTTGGCTGTGATATTTGCAGGAAACGTTTTGCAACCAGCACTGAATTACGAGATCATCTGCTGCGCCACGCAGGGATTAAGAATTTTGTGTGTACTTACTGTGGAGTGCGGAAAACAACTAAGCAGGAGCTCGATACTCACATCTTGACGCACACCAGGGAGAAGAACTTAAAATGCGATAAATGTGACTATTTGACCCATTGCAAGCAATCTCTGTGGAAGCACAATCGGGTGGTACACATGAAAATCAAAAAGCACGCCTGCAACTACTGTGAGAAGGCCTTTGGCAATGCCTACGCCCGGAGGACACATGAGAGATTACACACAGGAGAAATTTGCTTCGAATGTACGATCTGCGGCAGGATGTTCCTCTTCGAGAAGACCTTGAAAACGCATTTGAAAGCGCACGAGAAGCGTGAAAAATTGGAAACCGATAAGAAAGAAACCCCGAAGAAGGAAAAGAAATTGGGCGCACGAGTTGAGCGTGTGGAACTAGCACGATTGGCAGGCACTGTTGTTAATCCTATTCCAAAGGTGTCGGTTCCACCGCCTGCTTGGCAAGATGTAGAGCACAAAGATGGCCAGGTTTTATGTCCGGAGTGTGGCAAGAGTTTTAATCGCAAGGAAGGCATGAAGCTGCATTACAAGGTGGTTCATCAGAAGGTCAAGGATTACATTTGTCGCTTCTGCAGCAAACGTTTTGGCAGGCTGCAATATCTCAAGGCTCATGAGAATATTCACACCGGAGCCACGCCTTTTAAGTGCGATATATGCGACATGGCATTCAAAGGAGATTCGGCCTTGCATGTTCACAAAAAGAGACACCACAGGCCCAAGATAGCAAAGCCAGCGAAAGTGCCGAAGGCCCCGAAGCCGAAGCCTTCAAAATCTGCAAATGAATCTCAAACTACTAATTGTTTAACTAGGCGATCGAAAACGAAACTAAATACTCGGCCTAAAAATCAAAACCATGAACAGTATGAGGATCCATCTGCCGAACGAGCAGCGGCCCAAGCTCAGTTGATTGCACATGAGGAGAACAAGAATGAGTTGAAGATGAAGGCGGCCGAACAGATTCAGAAGATTCAAACGGCAGCTCAGGAGCAACTTGAGAATTTGAAGCGTCTAAACGAAAAAATGGCCCTTGATAGTTTATCAGTACAGACAAATAGTTGTACTTAA
Protein Sequence: MSEENLGIAQKFCRTCIKELSQDDAFDIFIVPGLAKKLCVCTSLSVEHHDGFPTNICPACYRRLNDLHDFQEQCVNSMQKFKEMLVTSCNFSVVNAAGDQEAEVSFEEQEHTHFDPLLNGKIEIEYEQDVLKMIEEVDKESVEDKVERQQSIDSVDNNESDDNEGIDFEGDSSDSDFTLPLSSLKRITKKSKGAAQVTTESKPKPQRMLECHICTQKFKKSSNYQEHMKQHDDQLPHQCPVESCKTGFTTPHGLRHHIEHMHTELCQMFACTVEGCNKQFPIKRSLTRHLRIMHNMAKPETHPCTECDKIFRCPMALKKHMYKHTGEEMPFGCDICRKRFATSTELRDHLLRHAGIKNFVCTYCGVRKTTKQELDTHILTHTREKNLKCDKCDYLTHCKQSLWKHNRVVHMKIKKHACNYCEKAFGNAYARRTHERLHTGEICFECTICGRMFLFEKTLKTHLKAHEKREKLETDKKETPKKEKKLGARVERVELARLAGTVVNPIPKVSVPPPAWQDVEHKDGQVLCPECGKSFNRKEGMKLHYKVVHQKVKDYICRFCSKRFGRLQYLKAHENIHTGATPFKCDICDMAFKGDSALHVHKKRHHRPKIAKPAKVPKAPKPKPSKSANESQTTNCLTRRSKTKLNTRPKNQNHEQYEDPSAERAAAQAQLIAHEENKNELKMKAAEQIQKIQTAAQEQLENLKRLNEKMALDSLSVQTNSCT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00589703;
90% Identity: iTF_00589703;
80% Identity: -