Basic Information

Insect: Drosophila serrata
Gene Symbol: -
Assembly: GCA_002093755.1
Location: NW:1996560-1997939[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.048 3.1 8.1 3.4 2 21 173 192 172 193 0.92

2 7 0.0017 0.11 12.7 0.3 2 20 201 219 200 221 0.92

3 7 1.6e-06 0.00011 22.2 4.6 1 23 228 250 228 250 0.98

4 7 1.3e-05 0.00085 19.3 1.2 1 23 263 285 263 285 0.98

5 7 1.9e-05 0.0012 18.9 1.0 1 23 291 313 291 313 0.98

6 7 6.3e-09 4.1e-07 29.8 2.8 1 23 319 341 319 341 0.99

7 7 0.0015 0.096 12.9 5.0 1 23 347 370 347 370 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.048	3.1	8.1	3.4	2	21	173	192	172	193	0.92
2	7	0.0017	0.11	12.7	0.3	2	20	201	219	200	221	0.92
3	7	1.6e-06	0.00011	22.2	4.6	1	23	228	250	228	250	0.98
4	7	1.3e-05	0.00085	19.3	1.2	1	23	263	285	263	285	0.98
5	7	1.9e-05	0.0012	18.9	1.0	1	23	291	313	291	313	0.98
6	7	6.3e-09	4.1e-07	29.8	2.8	1	23	319	341	319	341	0.99
7	7	0.0015	0.096	12.9	5.0	1	23	347	370	347	370	0.97

Sequence Information

Coding Sequence: atggaGAACCTGTGTCGAATATGTGGCACTCACTCCATTACCTTGGTGGGTATTTTCGACCAACGCCAACGGCGACAATTCAAGGGAGAAGTGGAGCCCAATCTCGCCGACATGGTTAAGAAATGCGCCGAAGTCCAAATAGATTCTGGTGATCCCTTGCCACAGAAAATCTGCAGGAACTGCATCCAGGACGCTCAGATTGCTTATAGATTCAAGCGCAGATGCGAACAGAGCTACCAGAAATTCTACTTGGCGATTGCGAATCAACCGGAAATCAAGAAAGAGTCAAAGGACCCAGGAGACCACTTCATTATCGAGGAGCACTTTGACAACGCTGTGGATATAAAGCTGCTGGTGGATATAAGAGAGGAGAGCTTTGACCAGACAAGTACCAAAAAAGAACTGCCAAAAATGGTTCCTGGTCAACCAAAGAAAGTCCAACAGGCAATACGCGAGTCCAGCAAGGAGTACCAAAACAGTCTGTTGGAACATAATaaAATTCAAAAAAAGTCCTGCACTTGCCAAACGTGCGGAGAAAGTTTCATGTTTGAAACCGATTTGGATAAGCATTTGTGTTTTAGCATTAGTGACCCCACCGTGGAGTGCCCCATTTGCCTAAAGGTCTTCTCCACAAGCCGTGGCTTGGACATCCACAAATGCCAGCCGATGAAAAAGAGACCTTTCGAGTGTCCACACTGCCCGCAAACCTTCACCCACAATCATTACCTTAAAGCCCACCTGTTGATTCACCCGGCAGACGAAACCGGCCAGCTAGCCATCGGTCCCCACAAGTGCACCATGTGCCGTGCTGGATTCGCTAACAAAGCGTCTCTTAAGGTTCATGTCCGTACCCACCTGGAAGAGCGGCCGCACAGCTGTCCGATTTGCGCCTCAAACTTCCGCTCGAAGCAGGCCCTCAAGGTCCACATCCGGACTCACACGGGCGAGAAGCCCTACCAATGCCCACACTGCCCCAAGACCTTCTCCGATAATAACAACCTGGCCAAGCACCGGCGCCGTCACTCAGACGAGCGGCCCTACAAGTGCCTGATATGCCTTCAGGACTTTCGGGAGAAGCACCACCTAAAGCGCCATGTCCTGAGTAAGCATCGCGACAGCGATGGAGAACAGCCATTGAAGTGA
Protein Sequence: MENLCRICGTHSITLVGIFDQRQRRQFKGEVEPNLADMVKKCAEVQIDSGDPLPQKICRNCIQDAQIAYRFKRRCEQSYQKFYLAIANQPEIKKESKDPGDHFIIEEHFDNAVDIKLLVDIREESFDQTSTKKELPKMVPGQPKKVQQAIRESSKEYQNSLLEHNKIQKKSCTCQTCGESFMFETDLDKHLCFSISDPTVECPICLKVFSTSRGLDIHKCQPMKKRPFECPHCPQTFTHNHYLKAHLLIHPADETGQLAIGPHKCTMCRAGFANKASLKVHVRTHLEERPHSCPICASNFRSKQALKVHIRTHTGEKPYQCPHCPKTFSDNNNLAKHRRRHSDERPYKCLICLQDFREKHHLKRHVLSKHRDSDGEQPLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00490280;
90% Identity: -
80% Identity: -