Basic Information

Insect: Drosophila serrata
Gene Symbol: hang
Assembly: GCA_002093755.1
Location: NW:1370938-1386674[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.26 17 5.8 1.0 3 23 307 328 306 328 0.93

2 19 0.83 54 4.2 3.1 3 22 436 455 434 455 0.89

3 19 0.00056 0.036 14.2 3.3 1 22 576 597 576 599 0.90

4 19 0.064 4.1 7.7 0.1 2 21 611 630 610 631 0.93

5 19 0.00064 0.042 14.0 0.2 2 23 765 787 764 787 0.95

6 19 0.0019 0.12 12.6 0.1 1 23 795 818 795 818 0.96

7 19 1.5e-05 0.00097 19.2 0.1 2 23 905 926 904 926 0.97

8 19 0.00027 0.017 15.2 2.9 2 23 1007 1029 1006 1029 0.97

9 19 0.021 1.4 9.3 0.2 2 23 1038 1060 1037 1060 0.95

10 19 0.002 0.13 12.5 0.1 1 23 1073 1096 1073 1096 0.97

11 19 0.00012 0.0075 16.4 1.1 1 23 1161 1183 1161 1183 0.99

12 19 0.0018 0.12 12.6 0.9 1 23 1191 1214 1191 1214 0.96

13 19 0.7 46 4.5 0.3 2 19 1222 1239 1222 1240 0.93

14 19 3e-05 0.0019 18.2 1.4 3 23 1328 1348 1327 1348 0.98

15 19 0.0047 0.3 11.3 0.1 1 23 1383 1405 1383 1405 0.97

16 19 0.00055 0.036 14.2 0.6 2 23 1491 1513 1490 1513 0.93

17 19 0.51 33 4.9 0.1 2 20 1533 1551 1532 1553 0.91

18 19 0.0061 0.4 11.0 0.4 3 23 1568 1588 1568 1588 0.98

19 19 9.4e-05 0.0061 16.7 2.1 1 23 1908 1930 1908 1930 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.26	17	5.8	1.0	3	23	307	328	306	328	0.93
2	19	0.83	54	4.2	3.1	3	22	436	455	434	455	0.89
3	19	0.00056	0.036	14.2	3.3	1	22	576	597	576	599	0.90
4	19	0.064	4.1	7.7	0.1	2	21	611	630	610	631	0.93
5	19	0.00064	0.042	14.0	0.2	2	23	765	787	764	787	0.95
6	19	0.0019	0.12	12.6	0.1	1	23	795	818	795	818	0.96
7	19	1.5e-05	0.00097	19.2	0.1	2	23	905	926	904	926	0.97
8	19	0.00027	0.017	15.2	2.9	2	23	1007	1029	1006	1029	0.97
9	19	0.021	1.4	9.3	0.2	2	23	1038	1060	1037	1060	0.95
10	19	0.002	0.13	12.5	0.1	1	23	1073	1096	1073	1096	0.97
11	19	0.00012	0.0075	16.4	1.1	1	23	1161	1183	1161	1183	0.99
12	19	0.0018	0.12	12.6	0.9	1	23	1191	1214	1191	1214	0.96
13	19	0.7	46	4.5	0.3	2	19	1222	1239	1222	1240	0.93
14	19	3e-05	0.0019	18.2	1.4	3	23	1328	1348	1327	1348	0.98
15	19	0.0047	0.3	11.3	0.1	1	23	1383	1405	1383	1405	0.97
16	19	0.00055	0.036	14.2	0.6	2	23	1491	1513	1490	1513	0.93
17	19	0.51	33	4.9	0.1	2	20	1533	1551	1532	1553	0.91
18	19	0.0061	0.4	11.0	0.4	3	23	1568	1588	1568	1588	0.98
19	19	9.4e-05	0.0061	16.7	2.1	1	23	1908	1930	1908	1930	0.98

Sequence Information

Coding Sequence: ATGTGCGACGCTGTGGCAACGGCGTCGGAGACGGCGACCACAGCGCTGCTGGGAGGAGCTAGTGGAGTGACGGCGTCTGGGGCTGGAGCAGCCATAATCACATCCACATCCCAGCCAGAAGCCTCAGCTTCGGCAACCGTTACACCAACCACGACAATGACGACGACGCCGCTGGTGGCGAAGAGTGAGCGGGCGGCGCGACAAAACTGCTGTCGCTTGTGCATCGCTCCGGCCAGCGAGTGCATCTCGATCATCAACAGCTATGCGGCGGACAAGGAGCCGCTGTCCACCAAGATCCACAACTGCGTCAGCATCAAGATCACATCACAGGATCGACTGTCGCTGCACATATGCCACGCCTGCATCAGCTACCTGAACTCGTGGCAGAGCTTCAAAAACCGCTGCCTCAGCTCACAGACAAAGCAGCGCCAGTGGCTGGACACcagcaacaaaagcaagcTCTTCAACTATCTGGACCTGAACAGTGCCGAAAACGGTGGAGGCACCTCCGATCACCAACAGCAGCATTCGCAGCCGCATCAATCGCAATCGGAGAATGAGCTGGACGCGGAGAAGGCGACGGCAGCGGCCACAACGGCCGCCAACATATTGGATGGCATACCATCGCTGAAGAAACGCAAATCCCTAACAGTCTATCCGCTGCCAGCGTTGCCCATCAAAGATGAGCCCATTGACACGGACGATGACTACCAGATGAAGATGATAGACGAGTCCGACGACATGGTCGATCCCACAATGTTCCTAGAGCGTTCCGAGCACGAGGGCGATATGCCGTTAATGGCCTCAGACTACGACTACACGGCCCAGCATGGCGTTAATGCTCATTCTCTGGCCGCCGGACTGCCACCGAATGCGGTTGCCAATGTGGCCGCCGCCGGGGATTCCAAAGTAGCCAGCTGCCGGGCCTGCAGCCTTCAGTTCTCCACCCGAGCCAATGCCCGTCGGCATGAGCGCAATCTACACCCGAACCTCTTCCAGCTGTCTACGGACTCGCTTCACAACACATCAGTTACGAAGCCAACACCAGCTCTGGCCGCCGCATTGGAAATCCAGcgggcggcagcagcagcggccaCTGCAGAGGCGAACCGTGCTGTGGGCGCTGCTGGTGGAAATATCACTCCACAGAAATACCGTCAGGTGGTGATGAATGCGTTTATCAAATGCGAAGGCGGTGGCTACGACTATGACAATCCGGAACAGTATCGTCCACTGCTCACCCACGACAAGGTGGAGTTCATCGAACAGAATGAGGAGTTCCTCGAGCAGTACCAGACTATGacctgccgctgctgcagcaaGTACTTCAGCACGTACAAGAACTTCATGGCGCACGTGCGCAAGAAGTATCCGCTGCTGCCGCGCAATCTATGCTTTAACTGCCTGAAGATGAACGACTCTAAGGCGTTGTTCATCTCGCATCTCAAGAAACGCAACTGCATAAATCTCTACAGAGTTTTGAATACGCTGCGTGGCAAAACACCAGTGCTTCCCATTACCGCCacggatgtggatgtggatgcagCGACAGCGTCGGCTGAAGATGGAGCCACAGCTGTAGCTGTAGCGGTGGCAGATGCCGGTGCTGGCGTTGTCACAATGGCCAGTCCCACGGTGACCATTACTGGAGAGACCTCCGGCACTACCGGCGGTGGTGAACGGCCAGAGAAGTTGCGAGCCAAGGAACTGCTAGTGAACAAGCTATACGAATGCAAGCTGTGCCCCAAGGGTTTCCGCACCAAGCACGAGTTCCGCACCCATGTCTACGACAAGCATGCGGATGTGCAGCGCAAGGATAACAACTCGATACAGTGCAGCTTCTGCGGCCTGGACTTTGCCGATCCGGTGGACAGGCGTCGCCACTACAATAATATGGACTGTATTGTGCGTCTGCGCTGCATGACCTGCGATGCCAAGCTGGAGACGCATCAGCGCTTCCTCGATCATGTGTACCAGGATCATCTGGGTGGCGTgagcggtggcggcggcggtgccAGCAGTGATAATGCCTCAACGACAGGCAGTGGCCTGGCCAGAAGCAACAGTATGGAACACTCACCGGGCAAGAGGAGTCTGCTTGGTGCCCTAGGCATAGGCATTGGCTCATCGGCTGAAGAGTCGCGCAGCAGCAGTGTGGCACCCACACTGACGTCCACACCCAAGCCAGCGGGAGGCACGGCCACAACGGCCTCCTCTGCCTCTGCGCCCAGTTCGACCAATCGTGGTGATGCGGCCGCACCCAAATCCCAGTACTTTTCGCGAATGCCGCAGGTGTGTCCCATTTGCGGACAGCAGTACAATAACTACAACAACGTGCTGCGCCACATGGAATCGAAACATCCAAACAAACTCCCCGAAACATACAAATGCGTACGCTGCGGCCTGGGCTATCCACGGATCTCCTATCTGCGGGAGCACATGATCAATGTTCATGGCGTGGACAAGAATCGGCACTCGGGCGGCTTCGAGTACATTGTGAATGCTGATGCCGTGAAGTTGGCGGATGGCAGCACGCCGAATGTGTACACGGGTCGCTACGACTACGTGATGAAGGACTTGATGTCGATAACAAATGGTGGGACCCTCGACGAAGACGATGAGGAGGCAGCTGGCAGCGTGGCCAAGAAAATCCGGCTCGacgacagcagcaacaacagcagcttGGCGGGCGTCGCCAGTCAGCAGCAGAAGGAATGTCCCATCTGTAATGCAGTGTTCAGCAACAACATTGGGCTTTCCAATCACATGCGCTCCCATTATACAGCTGCCAGTGTGGTGACCGCAGCTCTGGCGGCCGCCAATCGCATGACACCTAAATCACTGACCATAACAGCAACTCCAGCGGCAACAGACGCGACTCCAGAGGCGGAGACGTATACCGCGTCGGCCCCCAGCAGTAATGTTGTGCCACCGGCGATGGCCAATCAAACGCCTCAGGAGCAGGCCGTATTTCGTCGGAGTTTGGATCAGGCGGCCGACCGTCGCTTCCGGCGAATGCGTTGCCGGATTTGCCAGCGGCGTTTCAGCTCGAAGAAGTCCTATCGCTATCACATGCTGACAGACCATCAGGTGCAGAATGTGCAGTTTATCAAGTGCAAGCTGTGCAACGCGGAGTTCGCCTACGAGAAAGGTCTGAAGGTTCATCTGTTTAAGGTGCACGGTCGGGCCATCAAGGACGAGATGATTATCAAGCAGTTCGAGTGCGAGGTCTGCTCGATTGTATACAGCTCGGAGTTGGAGCTGCAACAGCACAAGCGTAGTGTCCACAAGCTGTCCTCGGCATCGGCCTCTGCTTCTGCCTCAGCATCTGCATCGGCGTCCGCCTCCACTTCATCGAAGATGGAAGACGACGGTTTgatagacgaagaaggcaagCCAACAGCCGGTGGTGATCATGCCGATCTGTCCACTCTTTCTGCCAACGCATCGGGACTGGGAGTGGGTACGCCGCTGTATTGGTACCAATGCAAGTACTGCCCTTCGAACTTCAACACCAACAAGAAGCTGGCCATTCACATTAACTCGCACGACGAGTTTGACTCAAATGATTACTCCTGCAAGGATTGTGGCAACGTGTATAGTGGACGCAAGAGTCTATGGGTGCACCGCTACAAGAAGCATCCTCAGGTGCCAGATCCGGCCGAATGCTCGCTGTGTCGCAAGATCTTCTTCGATCGTCAGATGCTGGACAACCATACGCCCACCTGCAACCGCAAGCCAATCACCTCGACGGGCGCACACCAGCAGCAGGAttcgctgcagcagcagcaggcagcacTGCAACGTGCTGTTTTCAGGCACAAGACGggtgacgatgacgatgaggaagATGATGGCCAACAACAGCTAGAGGAGGGTGATAGCAATGGGGGAGTAACAGCGTCGGCATCGGGAAGTGCAGCCGTGGCAGTGTCAGCTTCTGCCCAGGCCGCACTGAAGATTCGCATACCGGAGGTGGCCTGCACCATTTGCGGGGCCCGATTCACCGATCAGGAGCATTTTAGCAAGCACATCCAGAAGCATGAACAGGAGCTGTATGTGGACGATCCGCTGGCGGCAATGTTTGACGATGGGCCGGCGGATGCCGGTCAGTTCCAGGTTGAGCGGCAGAACGAGAACGGGGAATATGCGTGCGATTTGTGCGCCAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCCCATCGACGTCGAAGCGACACAGTTGACCAACAACAATCACActaccagcaacaacaacaacaacagcagctcGATGTCACACCTCCGCGAGCTGCATGCGGTGGGCCTGATGCccaaccagcagcagcaacagcagggcCACAACAGCAACtcaagcaacagcaacaacaatatgaatcacagcggcggcagcagcagcagcaagtcgATGAAGCGGAAGCGTGAGCTGAAATGCGAGTACTGCGCCTCCACCTtcatcagcaacaacaatctGCGCCGCCATATGTATGAGCTGCACAAGCACGAGGTAAGCAATCTTCCGGAGCCGCCGGTCATCTTGGTGGACGATCATCTCCAGTGCCGTCGCTGTCAGCTCAGTTTCGAGACAAAGGAGCTGTGGATCGAACACAAGCTGGCGGATGCGAAGGTGGTGCGTCCGTTCTGTCCCTTCCAGTGGGGTTGCGACCTGTGCGGCGAGTATCTGTCGCGGAAGGAGAAGCTGATGAATCACATTAACAACCATCTCAAGGAGGATGTCATTGTGCCGGTGGCCACAAAGGCGGCCATTGATCGGGAAGCGACGGCAATGGCAGCGACATCAGCAGCTGGGAATGCGGCGGAATTAACAGCAGATGATGGAGATCAAGATCGGGAGAACGAAGCTCGGGACAACAACGATAAGGCGGTAGTGGGAGGAGCACAAAAAGAAGAGGAAAGTGATGACCTGGACGAGGATGATAGCTCAGGCGAGGAGGAGGAAAGTTCAGGCACGGGAgacgatgaggatgatgactctgatgatgatgaggatgatgacgACGGCGATGGAGGTGAAGGTGAAGATGAAGAAGGTGTGCAGCCTGGTCATCTCTTGccccaacaacagcagcagctccagcagcagctccagcagaAGCACCAGCAGCCGCAGCTCAATCAGGACGACGATGATCTTGTCGAGGAGGTTATTAGCTCAGGAGACGAAGATGATGGCGAGGTGGAGAGcgacgatgatgacgatgacgatgtcgaggaggatgatgatgaggatgtCGACGATGAGGATGACGATGTGGAGGAACCGGAACCAGTGGCAGTGACCCTACCGCCATCGCAACCCCTGATGAATGGCAATAGCAAGGCCAAGTCAAAAATGCCGCCACTGATTATGGCCAGTtccgacgaggaggaggatgatggTGTTATGCCCATCGATGATATTATCGAAGAGGAATTCGACGAAGATGACGCCATGCCAGATCCAGATGCCGATCCGGATGTGGATGATCCCATCGAGGAggtggatgatgatgatttggATGAGGGGGATGATGTggagatggaggaggaggtggtgtCGGCAGCCTCCTCATCGGAGAGCGAGTCCACATCAACGACCACGTCCAATTCGCACTCGCATTCACATTCCACGGGTGAGCGGCGTAAGAAGAGGGCTGACGATCAGTTGAATGATCCCAGCTTTACCTGTGATCTATGTCAACTTTGTTTTGATTCCCAGGAGCTACTCCAGAGCCACATCAAAAGCCATTTCCTCAATGGACCAAAGCTtacagtggcagcagcagcaacaatgccAGTCGCCGccgcaccagcagcagcaacaacagcagccggCAGCGCGGCGGCATCGTCAAAATCGTCACTAACAACGGCGACGGCGCCAGCAAAGACGAAGCCTGACTCCAAGTCAGCGCTGcctgccaacaacaacaataagagCAGCAAGActgttgcagctgcagctgccacTAACTGA
Protein Sequence: MCDAVATASETATTALLGGASGVTASGAGAAIITSTSQPEASASATVTPTTTMTTTPLVAKSERAARQNCCRLCIAPASECISIINSYAADKEPLSTKIHNCVSIKITSQDRLSLHICHACISYLNSWQSFKNRCLSSQTKQRQWLDTSNKSKLFNYLDLNSAENGGGTSDHQQQHSQPHQSQSENELDAEKATAAATTAANILDGIPSLKKRKSLTVYPLPALPIKDEPIDTDDDYQMKMIDESDDMVDPTMFLERSEHEGDMPLMASDYDYTAQHGVNAHSLAAGLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSLHNTSVTKPTPALAAALEIQRAAAAAATAEANRAVGAAGGNITPQKYRQVVMNAFIKCEGGGYDYDNPEQYRPLLTHDKVEFIEQNEEFLEQYQTMTCRCCSKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNTLRGKTPVLPITATDVDVDAATASAEDGATAVAVAVADAGAGVVTMASPTVTITGETSGTTGGGERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSGGGGGASSDNASTTGSGLARSNSMEHSPGKRSLLGALGIGIGSSAEESRSSSVAPTLTSTPKPAGGTATTASSASAPSSTNRGDAAAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDEDDEEAAGSVAKKIRLDDSSNNSSLAGVASQQQKECPICNAVFSNNIGLSNHMRSHYTAASVVTAALAAANRMTPKSLTITATPAATDATPEAETYTASAPSSNVVPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECEVCSIVYSSELELQQHKRSVHKLSSASASASASASASASASTSSKMEDDGLIDEEGKPTAGGDHADLSTLSANASGLGVGTPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECSLCRKIFFDRQMLDNHTPTCNRKPITSTGAHQQQDSLQQQQAALQRAVFRHKTGDDDDEEDDGQQQLEEGDSNGGVTASASGSAAVAVSASAQAALKIRIPEVACTICGARFTDQEHFSKHIQKHEQELYVDDPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIDVEATQLTNNNHTTSNNNNNSSSMSHLRELHAVGLMPNQQQQQQGHNSNSSNSNNNMNHSGGSSSSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVILVDDHLQCRRCQLSFETKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLMNHINNHLKEDVIVPVATKAAIDREATAMAATSAAGNAAELTADDGDQDRENEARDNNDKAVVGGAQKEEESDDLDEDDSSGEEEESSGTGDDEDDDSDDDEDDDDGDGGEGEDEEGVQPGHLLPQQQQQLQQQLQQKHQQPQLNQDDDDLVEEVISSGDEDDGEVESDDDDDDDVEEDDDEDVDDEDDDVEEPEPVAVTLPPSQPLMNGNSKAKSKMPPLIMASSDEEEDDGVMPIDDIIEEEFDEDDAMPDPDADPDVDDPIEEVDDDDLDEGDDVEMEEEVVSAASSSESESTSTTTSNSHSHSHSTGERRKKRADDQLNDPSFTCDLCQLCFDSQELLQSHIKSHFLNGPKLTVAAAATMPVAAAPAAATTAAGSAAASSKSSLTTATAPAKTKPDSKSALPANNNNKSSKTVAAAAATN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00527463;
90% Identity: -
80% Identity: -