Basic Information

Insect: Drosophila serrata
Gene Symbol: zfh1
Assembly: GCA_002093755.1
Location: NW:859771-866354[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.4e-05 0.0016 18.5 1.0 1 23 153 175 153 175 0.97

2 15 0.00074 0.048 13.8 1.2 3 23 183 203 181 203 0.94

3 15 0.00024 0.016 15.3 0.2 1 23 363 385 363 385 0.98

4 15 0.00012 0.0078 16.3 0.8 1 23 391 413 391 413 0.98

5 15 1.3e-05 0.00082 19.4 2.3 1 23 445 467 445 467 0.97

6 15 0.009 0.59 10.4 1.2 1 23 501 523 501 523 0.93

7 15 0.0096 0.63 10.3 1.3 1 23 529 552 529 552 0.97

8 15 0.024 1.5 9.1 0.4 3 19 561 577 560 578 0.95

9 15 0.00014 0.0091 16.1 5.6 1 23 587 609 587 609 0.97

10 15 0.042 2.7 8.3 0.4 2 23 615 636 614 636 0.96

11 15 8.2e-06 0.00053 20.0 1.0 1 23 645 667 645 667 0.98

12 15 0.00093 0.06 13.5 0.1 3 23 675 695 673 695 0.97

13 15 5e-05 0.0032 17.5 0.5 1 23 701 723 701 724 0.95

14 15 0.033 2.1 8.6 0.3 1 23 734 756 734 756 0.97

15 15 0.005 0.33 11.2 0.2 1 23 1300 1322 1300 1322 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.4e-05	0.0016	18.5	1.0	1	23	153	175	153	175	0.97
2	15	0.00074	0.048	13.8	1.2	3	23	183	203	181	203	0.94
3	15	0.00024	0.016	15.3	0.2	1	23	363	385	363	385	0.98
4	15	0.00012	0.0078	16.3	0.8	1	23	391	413	391	413	0.98
5	15	1.3e-05	0.00082	19.4	2.3	1	23	445	467	445	467	0.97
6	15	0.009	0.59	10.4	1.2	1	23	501	523	501	523	0.93
7	15	0.0096	0.63	10.3	1.3	1	23	529	552	529	552	0.97
8	15	0.024	1.5	9.1	0.4	3	19	561	577	560	578	0.95
9	15	0.00014	0.0091	16.1	5.6	1	23	587	609	587	609	0.97
10	15	0.042	2.7	8.3	0.4	2	23	615	636	614	636	0.96
11	15	8.2e-06	0.00053	20.0	1.0	1	23	645	667	645	667	0.98
12	15	0.00093	0.06	13.5	0.1	3	23	675	695	673	695	0.97
13	15	5e-05	0.0032	17.5	0.5	1	23	701	723	701	724	0.95
14	15	0.033	2.1	8.6	0.3	1	23	734	756	734	756	0.97
15	15	0.005	0.33	11.2	0.2	1	23	1300	1322	1300	1322	0.97

Sequence Information

Coding Sequence: ATGAACAACCAGGACTATGGCGGCATCCAGTGGATACAGCACCATCCCGCTGCAGGGGACTCTTCTGAAACGGACATTATGGAGCACGAAGACGCCGACGGCGATGATATGGTGAGCGGAGCGGACGGTGACCCAGACGGGGATGGGGATGCGGATGCTGACCTAGACCATATGGCTGCCGAGAACCTTATCTTTATGGCGCGCGACGGCCAGCTGGGCGAGATTATTGCCGCCAACGAGGGAACTGTCCTCGTCACCGCCGATGGCACTACCGTGGCTTATGCGGAATCCTTTGATGATGACGCCCAGGTGGTTACCGAGGAGGTCATCACCGACGACTGGGTGCAGCACCAAGGAGCCGAGCGAGTGGAAATTGCCGCTGAGCAAATAGCTGGCATCGGAAGCTCGCAGGAACTGTTGGACATGGAACAGGATGAGTACACGGCCCTGCGACCCTATCCCTGCGACTTTTGCAGTCGCCGGTTTCGGAAGAAGGCTAGCTTGAACAACCATATGCTGGCCCATCAAAACGATCGACCTCATCTCTGCAAGCTGTGCGGAGCACGCTTCTCACGCCGGGCGGAGCTTATTAGCCACTTTAAGGCCCACGCCGAAGCCCAAGATGCTGCGGATGCCGAGGCAGCTGCGGCTGCCGCCGTTTCCTCTTCCATAAAATTTGAGAATCAGGGCCAGAGGCAGATTGATGATCACTACTACGAGCAGGAGTGGCCGCTgtatcagcagcagcagcaggatcagGAACAGGAGCAAGTGCAACATGAGCAGATGTTGCAACAGGAACAACAGCAACTAGTCTGCAACAATGAGGTCCAGTTCGTGGCCAGCTATACAGCATCGGTGGCTCCCCCTCCTGCTCCTTCGCGCGGAAGAATTAGCAGGCTGAAGCCCAAGGAGGAGAGCAGCCAGTTTGTCGTAATTACCGATAAGCCGGCGTCCAGTGAGCTGCATGACTACATGACCAGCGAGCCTGTGCCTCAGCCAGTGGTACCCACATCGCAGCCCATGGCCATTGATCCTCCGCCAGCGCCGCAGCCAAACTTCCCAGTGCTGGACGAAAGCAAGCCCTTCGTGTGTCAGCAATGCGGACTGGCTTTTGCTCGGGAAAAGGCGCTAGTCTCGCACACTAAGAACCATCGTGTAGACTCTCCCTTTGAGTGCAACCAGTGTCAGGAGATGTTCTGGGACAACAGCAGTCTGCAGGACCACCAAAAGACGCATCAGTTTGAGGAAAGCAACTCGGAGTATGATCCTGCCTCCGGCGATGATAGCGCCAGTGAAACGTCGGAGCCAGAGGACCAGCTCTACGGAGAGTTTTACTGCAACGAGTGCGGCATCTCCTTTCATCGCCAGGATCTACTGCGGCGACATGCCAAGCAGCATTTcaagcagcaggagcagaatTCAACGGTAGCTGCAGGCGACGGTAGCTCCTCGGACGTCATAGCTAGCTGCGAGCAGACTAAAGATGGTAACGGTGGGCACTGTTGTCAAACGTGCGGTAAATCATTTCCCAGTGCCTTGGAGATGCTTTCCCACGCCGAAATTCATGCGAGGTTTCCGCCTTTCAAGTGCGTACTTTGCGGCATAAGTTTCTACGAGGAGCAGGCCATCAAGCGGCACTTGCACACCCGTCATCCAAACGAACTAAAGGCCAATTCCTGTGTATTGTGCGGTAAGGAGTGTCGTGACCGCAAGGCTCTGATCAAGCATGCCTGGGATCACTCCCGCGAAAAGTGCCACTCTTGCTCCAAATGCGGCAAGAATTTTCACAACAAGGCGCGTTTGAAGCGGCACATGGCCTCCCACCGCGACAAGTCCGTTGTGTGCGAGGTCTGCCAGGAGGAGTTTCCCGACGGACGTACGCTGTCCAATCACCGTCACTCGCATAGCACCACGTCACCGGGCAAACTGTTTCCCTGCCACGAATGCGGAAAGACATTCGGATCACGCAGTTCCCAACAGATCCACGTTCGCATTCATACGGGTGAGCGTCCCTACGGTTGTAGGTATTGTTGGAAGGCCTTTGCCGATGGCGGGACGTTGCGCAAACACGAACGGATACATACGGGCGAGAAGCCCTACGCCTGCTCCGTATGTCCGCGTGCTTTTAATCAGAGGGTGGTTCTGAGGGAGCACATCCGCTCTCACCACTCGGGACTGGACGTGGCAAGAAATACCTACCATTGCACTGTCTGCTCCGAGGATCTGGCCTCATCCAATGACCTCATACAGCACCTCATCCAGCACAGTGATTCGAACACCGCCAAGCAACGTCAGCCGGTGacgGGACCGCGAAAGTACAAGCGTCGACGGAAGCTGCAGCCTCACGAAATTGCGCACATGCGAGCGGAACACAAAGATGCTAACGGCGGCGGCGACGAGGAGGAGGTTCTGGGAGGCGGAGGCGATGGCGATGGAGAGGAGTATGCCAGTGACATTGACCTTTGTGACTTTGATGTGGAAAATGTGGACGATCTGTTTGAAATGGCCGAGTCATCACCCAAAAAGGAGAAGCGCAAGAGGAAATCAGCAGCGGCATCCGCGAAGACAGAATCTAAACCTGTTTCCAATGGCGGCGCATCGTCGGCGAAGCTTGTTCAGGAGAAGAACACGGCTAAGCTGCGATATGACTCCACCAGCAGTCAGCAATCGGATCGCATTTGGGAGGAAAAATTCCTGCAGGACAGCCAGGTGGGTCTCTTCCAAATCGATTCTCTGGTGGTGGTCAACGATACTCACCTTCCACCCGCGAGCTCTTCGGTCATGCCCAAGACGAGAGGTAGctccaagcagcagcagcagcagcagcatcaggcCAAGCAACCCGTTGAAAGAGCTGGCAACTCGAATCCCTCAGCTGCAAGCTCAGTAGCTACATcatccgcctccgcctccacaTCCACTTCCAGCAGTCGCAGCAGGAAGAAGACGGCTGCGGTAAAAACAGCTGCTGCCTCGCGACCCCGTATGATACACACGGAGAAGGCCAAGGTGCCGTCCAGGGGAAATACCGGCGGAGACTTGTGCAAGAAGACACGCTCCAAGACCTACATAACCCGCACGGAGACAAGCAATCTGAGCAGTCTGGACAAGTCACGCAGCAGAGCCTCCAACATTGTGGATGACTACGAAATCATTTCACCGGCTACCCATCCTCCTAACCAGATCAGTTCCAGTCCCCTGCACATcaaacaggagcaggagcagcataaCCGTGTCCAGATGATGTACGACGACAATCTCCTGATAGACGCTGCCCTGCTGCGGGAGAAGACCTACGAGAAGTTCAATCCGAGCATTGTGAACGATCTGGAGGAGATCCTACGGTCGCCGCTCAAGCACGAACGCAATACCCGCCTGCGATTCACCAGTGAATCCTCGACCACGCCACAGTTTCTGCCTGAAGAAGAGCAGAATCTGATTAAGATCGAGCCCACGTCTCCGGATTTGCATGAGATGCTGGAGAGTCAGAGTCAAAGGGTGAGAGTACCAAGTGGCAATACACCGTCTCCCTCGTCTTCCTCCGCCGCCAGAACTTCTCGTCATCGTATCGTAAATGCCAATGGACCAAGGACAGCGAACAAAAGATCCGCAGGAGGAGGGGGTGCTAGCAGCGCTAGCAAATCCTCTCCTGCCACAGGAGTGGCGGCCAAGAAAGTGATCACTGCTGATAGTAAGGTCGGCAGTTCGTCCTCGTACCTCAATTACGGGGTGGATGCCTATAATGTGAACGTACCTGCCAGTTCCAGCACTGCCGATGTGGGCAGCGGATTCTTCTCCATCTCGGAGGTTGTATCGGCCGCGGATGCTGCCGATGCAGCTGATGCGGCAGCTAAGGCAGCGGCAGCTGGGAAACCGGATCGAAAAACGCGCAGTTTCGAGTGCGAAATGTGCTCGGCCATCTTTTATGATCGAGCCCAATTACTGGACCATGTGCACATTCACATTTAG
Protein Sequence: MNNQDYGGIQWIQHHPAAGDSSETDIMEHEDADGDDMVSGADGDPDGDGDADADLDHMAAENLIFMARDGQLGEIIAANEGTVLVTADGTTVAYAESFDDDAQVVTEEVITDDWVQHQGAERVEIAAEQIAGIGSSQELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAAAAVSSSIKFENQGQRQIDDHYYEQEWPLYQQQQQDQEQEQVQHEQMLQQEQQQLVCNNEVQFVASYTASVAPPPAPSRGRISRLKPKEESSQFVVITDKPASSELHDYMTSEPVPQPVVPTSQPMAIDPPPAPQPNFPVLDESKPFVCQQCGLAFAREKALVSHTKNHRVDSPFECNQCQEMFWDNSSLQDHQKTHQFEESNSEYDPASGDDSASETSEPEDQLYGEFYCNECGISFHRQDLLRRHAKQHFKQQEQNSTVAAGDGSSSDVIASCEQTKDGNGGHCCQTCGKSFPSALEMLSHAEIHARFPPFKCVLCGISFYEEQAIKRHLHTRHPNELKANSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVARNTYHCTVCSEDLASSNDLIQHLIQHSDSNTAKQRQPVTGPRKYKRRRKLQPHEIAHMRAEHKDANGGGDEEEVLGGGGDGDGEEYASDIDLCDFDVENVDDLFEMAESSPKKEKRKRKSAAASAKTESKPVSNGGASSAKLVQEKNTAKLRYDSTSSQQSDRIWEEKFLQDSQVGLFQIDSLVVVNDTHLPPASSSVMPKTRGSSKQQQQQQHQAKQPVERAGNSNPSAASSVATSSASASTSTSSSRSRKKTAAVKTAAASRPRMIHTEKAKVPSRGNTGGDLCKKTRSKTYITRTETSNLSSLDKSRSRASNIVDDYEIISPATHPPNQISSSPLHIKQEQEQHNRVQMMYDDNLLIDAALLREKTYEKFNPSIVNDLEEILRSPLKHERNTRLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLHEMLESQSQRVRVPSGNTPSPSSSSAARTSRHRIVNANGPRTANKRSAGGGGASSASKSSPATGVAAKKVITADSKVGSSSSYLNYGVDAYNVNVPASSSTADVGSGFFSISEVVSAADAADAADAAAKAAAAGKPDRKTRSFECEMCSAIFYDRAQLLDHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00480304;
90% Identity: iTF_00617778;
80% Identity: -