Basic Information

Insect: Drosophila serrata
Gene Symbol: ZNF296
Assembly: GCA_002093755.1
Location: NW:2031287-2035860[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 24 0.0012 0.077 13.2 1.6 1 23 210 232 210 232 0.96

2 24 1.5 97 3.4 3.7 1 21 239 259 239 261 0.84

3 24 0.021 1.4 9.3 0.4 2 23 293 314 292 314 0.95

4 24 0.0083 0.54 10.5 0.5 1 23 387 410 387 410 0.94

5 24 0.0049 0.32 11.3 0.0 2 23 485 506 484 506 0.96

6 24 0.00068 0.044 14.0 1.2 1 23 587 610 587 610 0.96

7 24 0.0021 0.14 12.4 0.5 2 22 621 641 620 641 0.93

8 24 0.018 1.1 9.5 1.0 3 23 652 672 651 673 0.94

9 24 0.0031 0.2 11.9 1.4 2 23 693 714 692 714 0.97

10 24 4.3e-06 0.00028 20.9 4.3 1 23 721 743 721 743 0.98

11 24 0.0071 0.46 10.7 0.6 1 23 878 901 878 901 0.91

12 24 0.0022 0.15 12.3 0.2 2 22 909 929 908 929 0.94

13 24 0.044 2.8 8.3 3.4 1 23 938 961 938 961 0.93

14 24 7.4e-05 0.0048 17.0 1.4 2 23 980 1001 979 1001 0.97

15 24 8.1e-05 0.0052 16.9 0.4 1 23 1008 1030 1008 1030 0.98

16 24 0.076 4.9 7.5 0.0 2 21 1057 1076 1056 1077 0.92

17 24 0.033 2.1 8.7 4.0 1 23 1123 1146 1123 1146 0.96

18 24 0.013 0.82 10.0 0.6 1 23 1183 1206 1183 1206 0.96

19 24 0.00084 0.054 13.7 1.6 1 23 1232 1255 1232 1255 0.97

20 24 4.7e-06 0.00031 20.7 0.2 2 23 1282 1303 1281 1303 0.95

21 24 0.0024 0.16 12.2 2.6 1 23 1309 1331 1309 1331 0.99

22 24 1.9e-06 0.00012 22.0 2.0 1 23 1337 1359 1337 1359 0.97

23 24 1.6e-07 1.1e-05 25.3 2.4 1 23 1365 1387 1365 1387 0.99

24 24 0.00061 0.04 14.1 0.1 1 21 1393 1413 1393 1417 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	24	0.0012	0.077	13.2	1.6	1	23	210	232	210	232	0.96
2	24	1.5	97	3.4	3.7	1	21	239	259	239	261	0.84
3	24	0.021	1.4	9.3	0.4	2	23	293	314	292	314	0.95
4	24	0.0083	0.54	10.5	0.5	1	23	387	410	387	410	0.94
5	24	0.0049	0.32	11.3	0.0	2	23	485	506	484	506	0.96
6	24	0.00068	0.044	14.0	1.2	1	23	587	610	587	610	0.96
7	24	0.0021	0.14	12.4	0.5	2	22	621	641	620	641	0.93
8	24	0.018	1.1	9.5	1.0	3	23	652	672	651	673	0.94
9	24	0.0031	0.2	11.9	1.4	2	23	693	714	692	714	0.97
10	24	4.3e-06	0.00028	20.9	4.3	1	23	721	743	721	743	0.98
11	24	0.0071	0.46	10.7	0.6	1	23	878	901	878	901	0.91
12	24	0.0022	0.15	12.3	0.2	2	22	909	929	908	929	0.94
13	24	0.044	2.8	8.3	3.4	1	23	938	961	938	961	0.93
14	24	7.4e-05	0.0048	17.0	1.4	2	23	980	1001	979	1001	0.97
15	24	8.1e-05	0.0052	16.9	0.4	1	23	1008	1030	1008	1030	0.98
16	24	0.076	4.9	7.5	0.0	2	21	1057	1076	1056	1077	0.92
17	24	0.033	2.1	8.7	4.0	1	23	1123	1146	1123	1146	0.96
18	24	0.013	0.82	10.0	0.6	1	23	1183	1206	1183	1206	0.96
19	24	0.00084	0.054	13.7	1.6	1	23	1232	1255	1232	1255	0.97
20	24	4.7e-06	0.00031	20.7	0.2	2	23	1282	1303	1281	1303	0.95
21	24	0.0024	0.16	12.2	2.6	1	23	1309	1331	1309	1331	0.99
22	24	1.9e-06	0.00012	22.0	2.0	1	23	1337	1359	1337	1359	0.97
23	24	1.6e-07	1.1e-05	25.3	2.4	1	23	1365	1387	1365	1387	0.99
24	24	0.00061	0.04	14.1	0.1	1	21	1393	1413	1393	1417	0.91

Sequence Information

Coding Sequence: ATGCTTCCTCCGAATATTTGCCGCACTTGTGCGATTCCGAACACGGATTTGCGGCCATTGTCCACCTGTCTGGCCAAAGACGCCTCAAAAAGTTTCTATGATGTGCTCCAGGAGCTAACGCAAATCGATCCCCTGGTTGAGAGCTCGGGTGATAGTCTGCCGCAGCATCTGTGCACCGAATGCCTGGCGAGATTGGAAAGTGCCTACGCCTTTGTGGAACAGGCTAGGAAAGTCAATGGCGAGCTGTTGGTTCGTCTGCGGGAATGCCTTGACGAAATGCCCATTGACATTccgcaggagcagcagcacatTAAAACCGAAGTAGATATCGAGGAGGCGGCTTCCAAGTATGTTGAGGATGTAGATTCCGCCCGTATATCGCCTGTGGAGTTCAAATGGCAGCCGGACAGTGAAAGTGATGGAGATTTTGCTGGAGCAGCATCCAGTAATGAGAATGAGCGCGAGAAAAAACCCTATCCCCTGAGACGCAGTGCGCGCAAAATCAAGCAGCCTGTAGAGAGCGATAATGAGGAATCAGAAGTACCAACAGAACCTTCGCCCAGCAAACGTCGTCGTGGCCGTCCCCCCGGCCCGGCCAAGCGCCAGTCGATGACCTCCGATGGCCGTCACGCATGCAAGGAGTGCGGCAAGACCTTCTCCTGGTTCCGTGATATGCAGCGCCATGCCCGCATCCATTTCGAAAAATCCAACGCCTACGTTTGCGACACGTGCGGCAAGGGTTTCTTACGCAAGGACAAGTACACATTCCATCTGCGCTGCCACGAAAAAAACGATGCCAAAAGCAAGGCTCTTCAGTTGGGGAACGAATGGCGCTTCGCCGAACGGCTATACAGTTCCGGCAGGTTGAAAAGGATCGAGTGCAAACTGTGCGGCCTGAAGTGCCCTCGGATTCAGGAGCTCAGAATTCACTTGGTCAGCCATAAGAACGTGGAGAGCCTGTTCCAGTTGAGGGAGAATAGCGATGTGATTAAAGAGCACTATGCTGACCAGCCAGGTGACTTGGACGGCGTCAAGGATCAAATTGTCGTGGACATAACGGAAGGGCACTTGGAGAAGTTCGCTTCCATAGTAAATTCCCATGGCTACGAGCTGGGGCTGTATGACTCGGACGAGGAATACGCTGGCGGAGAGTCAAAATATGAATGCACGGCGTGCAATCTTCCCTTTGCGAGGAAACATCAAGTGGTGAGGCACACACTAGAGGAGCACGCCCAATCATTTTCCTCAGAGCTTCCCTGGAAACGGTGCGACTTCTGTAATATCGGATTCCTCTGCTCCAGACTCTACGATTGCCATGTGAACAGCCAATGTGACAGCAAACTAAAGCGGTATCGATGCGCAAAGTGCCCAGGGAAATTTATGTGGCCGGAAAATCAGCACAGGCACGCGTGCTCCCATCGCCACGAGGAACTGGCGCTTTCCCGCCAGATCTCCTGCTCCTTGTGCGACGAATCGCTGCCCACTTTGGCCCAGTTGCGTATACACTTAGTTACCCACCAAAGTAACATGAGTGGCATCGATCCGGAGCATAGTTCGACGTTCTTTCGGTCGTTTTATCCGAACGGACTGGATTGCACTCGGGAGGAGCTGGGTGTCCGCATAGCCGAAGACTTCGAGGTGCAGGACTTCGATCGCTACTACAACGCCTGCACGGGCAGTGGCCAAGAGCTGGATCTCTTCGATTCCGAGACAGAGCAGAGTGGCGACGATAGGGAGGAGGATGAGAAGCCGAGCGCTCATACCTGTTTGTTGTGTGGAAAGGTGACGAACAGACTCACGTCCCTACTGCAGCACCAGAACAGTGTCCATTCAAAAGCGACGACGTCAGATCTGCCTTGTTCCTGCCAGGATTGTGGTGCTAGCTTCATAAGCGACGCCCTGCTGCAACAGCACCGCCGGCGTATCTGTGGAAAGAAACATTTCCGCCGTCACTGCCAGAGCTGTAATCTCCGGTTTATCTGGCCGAGCAACTACGAGCTGCATATGAAGACCCATCATAGCGAGGAGAGAGAGGAGAAACAAATCGATGAGGGTGAGCATCGGGATGCCAAGCTGCAGTGCGACGTGTGCGAAAAGGTTTTCATCTGGCATAAGGATCTCACGCGTCACAAACGCTTGCACCTGCCGCAATCGGCGCAGTTCGAATGTCCGCATTGTGACCGAAAGTTCCACCGCAAAGATGGCCTCAAGTCCCACCTGCGGGTCCACACAGCTGCCCAGCTTGTTGAGCAGCCTCTCGCATCCGACAGTAGCCAGATTCTTGCTCTGCTTTCCCGACCTCATGGCTGTAAGCAGATTCAGTGCATGATCTGTCTCTCACGCCACTCCAAGATCTCTGATTTGCGAACCCACCTGGCCGCTCATCAATACGGACTGAGCTTCACCGCGGAAACCGATGTTTTCAGTATCTCAAAGTATCTGTACCCGGAACTGGGAACGTCCTTGGACAGAGATCAACTGGCGGAGAGAATTATGGCAGATATCGACCAGGGACTGGATCTGGATCGATTTATTTCCATCACCAATGAAGCTGGCTTGGAGCTTAACTTGGACAGCAGTGAAACGGACTCTGAatccgaggaggaggaggaaaaccAGTCCAGCCAGAATTACGCCTGCAATCTCTGTCCCACGGAGGTGAAGAGAAAACATCAGCTTTATGCCCACCAAGGGGAGAATCATCAGTACGAGGAGGCACCTCTCGTTTGCCCGTACTGCCAGGCTAGGTTCGTCAACGAATCCCTGCTGTATCATCACTCCAGGACCTTTTGCGGCAATGTCCAGAAGCGCTTCCAGTGCCGGAAATGTCCGGTTCGCTTCCGATGGCGTGAGAACCTGAAGCACCACCTATATCTGTTTCATCAGCAGGCTGAGATGCTAGCTGCAGAGGATTCGTCGCAAGTGGATGCAGAACTGAAATGTGGTGAGTGCCAGCAAACGTTTAAGATGCAGAAAGATCTCACAAGGCACACCTTGATGCATGCCCGGGAGGCGACGATCTATCGGTGTCGCTGGTGTGCACGTCGATTTTACCGCTGGGCTAACCTCCTGCAACACATCGCGCGCCACGGCATCCGGGCTAGTGAGCTCCACTATGCCGAGGCCCTCCTGGACTCCTATGGACATCCAGGCGGTCAGAAAACCGTGGAGTGCCGGGTGTGCAATGTCAGCTTCGCCAGTATTGCCGCCCTGCGTCTGCATCTGGAGACCATGCCGGCAGGCAGTCACCACGAGCTCTCCTCGTTGAAGAACTATTCGATCACCAACCAAATGGGCTTTGAGCTGGATCTTCAGGATTCGGAAACGGATGAGGAGCAGGCGAAGCCGCCTGGCGTGCCTGCCTACTACACTTGTGGCATGTGCCAGCTGAGGTGCGTGAGGAAGTTCGAACTGCACCAACACCAGCAGGCCATGCACCGGCTGGAGAAGATTTCCGACGGCTGTGACCAGTGCATCTTTAAAAGCGTCTGTCCCGACATCATTGCTCATCACAAGAGGACCCAGTGTGCCAACCGGGAGAAGCAGTTTACGTGCTCCCGCTGCGGCTACAAGTTTATGTGGGAGGCGAACCTGCTTACGCACATGCAGCTGCAGCACGGAAAGACTGACAATCCGGAGCAGGAGGGGGACAAGGAGTCTCCAGCCGAAGAGCCTAAGACCGGAAGCCCAGTTTTCCAGTGTGCCCAGTGCCCCAGAAAGTACAACCGAAAGGATCGCCTGTCAGCGCACGTTAAAAAGTTCCATGGACCCGCTGGTAGGGGTCCCGAGGTCGCAAAGGTTCCCGCTACCAGAGCCACCTCACCCAAAGAACCGAAGCGCTTCCTGTGCGCCTTCTGTGGCAAGGCGGTCAGCTCCTCCTCCAACCTGATCATTCACATGCGACGTCACACCGGCGAAAAGCCTTTCAAGTGCGAGTTCTGCGCGATGGCCTTTCCACGGTCGTCGGACCTCCAGTGTCACCGGCGAACGCATACCGGAGAGCGGCCGCACGTGTGTACCGTGTGCCAGAAGGGATTCGCCCGCTCTTACAAGCTGCAGCAGCACATGCGCATCCACAGTGGCGAACGTCCGTACAAGTGCACCTACTGCGAGAAGAGCTTCACCCAGTCCAACGACCTGACACTCCACATCCGTCGGCACACGGGAGAGCGGCCCTATCAGTGTGGCATCTGCGGGGAACGTTTCATCCAGGGAACGGCGTTGAAGAATCATCGCCTGCAGCAGGGCCACTACGAGGAGGGTCAGAATTCTGGTGAGCCGGCAAGGCGCACGGTTTTGGAACAGTTCGCTGTATGA
Protein Sequence: MLPPNICRTCAIPNTDLRPLSTCLAKDASKSFYDVLQELTQIDPLVESSGDSLPQHLCTECLARLESAYAFVEQARKVNGELLVRLRECLDEMPIDIPQEQQHIKTEVDIEEAASKYVEDVDSARISPVEFKWQPDSESDGDFAGAASSNENEREKKPYPLRRSARKIKQPVESDNEESEVPTEPSPSKRRRGRPPGPAKRQSMTSDGRHACKECGKTFSWFRDMQRHARIHFEKSNAYVCDTCGKGFLRKDKYTFHLRCHEKNDAKSKALQLGNEWRFAERLYSSGRLKRIECKLCGLKCPRIQELRIHLVSHKNVESLFQLRENSDVIKEHYADQPGDLDGVKDQIVVDITEGHLEKFASIVNSHGYELGLYDSDEEYAGGESKYECTACNLPFARKHQVVRHTLEEHAQSFSSELPWKRCDFCNIGFLCSRLYDCHVNSQCDSKLKRYRCAKCPGKFMWPENQHRHACSHRHEELALSRQISCSLCDESLPTLAQLRIHLVTHQSNMSGIDPEHSSTFFRSFYPNGLDCTREELGVRIAEDFEVQDFDRYYNACTGSGQELDLFDSETEQSGDDREEDEKPSAHTCLLCGKVTNRLTSLLQHQNSVHSKATTSDLPCSCQDCGASFISDALLQQHRRRICGKKHFRRHCQSCNLRFIWPSNYELHMKTHHSEEREEKQIDEGEHRDAKLQCDVCEKVFIWHKDLTRHKRLHLPQSAQFECPHCDRKFHRKDGLKSHLRVHTAAQLVEQPLASDSSQILALLSRPHGCKQIQCMICLSRHSKISDLRTHLAAHQYGLSFTAETDVFSISKYLYPELGTSLDRDQLAERIMADIDQGLDLDRFISITNEAGLELNLDSSETDSESEEEEENQSSQNYACNLCPTEVKRKHQLYAHQGENHQYEEAPLVCPYCQARFVNESLLYHHSRTFCGNVQKRFQCRKCPVRFRWRENLKHHLYLFHQQAEMLAAEDSSQVDAELKCGECQQTFKMQKDLTRHTLMHAREATIYRCRWCARRFYRWANLLQHIARHGIRASELHYAEALLDSYGHPGGQKTVECRVCNVSFASIAALRLHLETMPAGSHHELSSLKNYSITNQMGFELDLQDSETDEEQAKPPGVPAYYTCGMCQLRCVRKFELHQHQQAMHRLEKISDGCDQCIFKSVCPDIIAHHKRTQCANREKQFTCSRCGYKFMWEANLLTHMQLQHGKTDNPEQEGDKESPAEEPKTGSPVFQCAQCPRKYNRKDRLSAHVKKFHGPAGRGPEVAKVPATRATSPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCEFCAMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGICGERFIQGTALKNHRLQQGHYEEGQNSGEPARRTVLEQFAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00491633;
90% Identity: iTF_00491633;
80% Identity: -