Basic Information

Insect: Drosophila seguyi
Gene Symbol: GLIS3
Assembly: GCA_008042675.1
Location: VNJU01008774.1:384520-389381[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.088 6.4 7.4 0.6 3 23 433 456 431 456 0.89

2 5 0.16 12 6.5 0.4 1 23 465 492 465 492 0.88

3 5 1e-06 7.4e-05 22.9 0.5 2 23 499 522 498 522 0.97

4 5 0.00081 0.059 13.8 0.8 3 23 530 552 528 552 0.92

5 5 3.3e-05 0.0024 18.1 0.4 1 23 558 582 558 582 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.088	6.4	7.4	0.6	3	23	433	456	431	456	0.89
2	5	0.16	12	6.5	0.4	1	23	465	492	465	492	0.88
3	5	1e-06	7.4e-05	22.9	0.5	2	23	499	522	498	522	0.97
4	5	0.00081	0.059	13.8	0.8	3	23	530	552	528	552	0.92
5	5	3.3e-05	0.0024	18.1	0.4	1	23	558	582	558	582	0.94

Sequence Information

Coding Sequence: ATGTCATCCACGCTGAAGAGCCTAGCCAGCCAGGGCGGCGGCATGTACGTCAAGACGTCGGATCTCGGCGGAATCTCGGGCAAGGAGCTCCCGGGCAGCTGCTTCGGCGGAGGCTTCATGTCGCCCCCGCTTAGTGCGAAGATGGTGACCGACGCAGACCGGGACATATTCCGTGTGCCGGCCAAAGTGGATTCCGTAGGACACAACAACTTCTCCGCCGGCGAGCTTCAGTTCCCGGACTTCTCGCACCTCTGCTTCGCCGCCGAGACGCCCAACTCGGTGTTTAGTGACTGCCACGCTCACTTGGGCCAGGATCAGCAGCAGGACTCGGACCAGGATCACGATCAGGACGACATTGTGTGCGCCGCTGCGGGAAACACGAGCATGCCATACCAGCAGGGTCAGTACACGCAGCTTAACCGCGAGGATATCTTCCGCTTCGAGCCGGAGGACATAGCCCGGCTCACGGGAGAGTCCGACCTGCCGGGTCTGCTGCAGCCACCACAGACTCCGTACACACCGTACACCCCGTACACTCCGTACACGCCATGCAGCGCCCAGAACAGTCAGCCGGCGGCGAGCGACTCCGTCAATCTGGATATTGATTACTTTAATTATGACGAGATTAATTGCCAATCGAAAAACCAATCTCCGTGCTCATCCCCGCCGCTAGATGCCTGGCTGAACTTCAATCTCGGGGAAATATCGGCGGCCGCGTCAGGTGCCTCGCCCAAGCTGGGCAACGTGTTTGAGGAGTACGtcaaggaggagcaggggCAGGAGCCCTCGCCCACCAAGCTGCCGTCGATGAACTCCACGTTCGGCACCCCCAAATGCATTCCCATGTGCGCCAGCAACTACGAGGACTACTCCAATCTGTACCAGGGTTCGGCCTACGAAGCCGAGACCTATCAGCACAATCTAGCGCAGTCCGTGGAGAAGCCCAACCGGGAGCACAAGGTAATTTGGACCATTGATGAGCTTGACGAGCTGGTGCTGGCCGAGCAGCAGCAATTCCATCAACATCAACtgcggcagcagcaagagcAACACCCACAGCAAGAGCAACTTCAATGCCAGAGCAAAAACCAGGACCTGACTAGCTACATGGCTGATGATTTAGTCAAGGAGGAACAGTATCGCAATTTGGACAGCGAAGATGAGGAAAACTATCCGGAAGAGGACGATGACTTGGACAATGAGGTGTTTGCTCTTCCGGCGGAAAGTGATCCAAAGCCGGATTCGGTTTGTTGCGATCCCGAAGCGGAGACGGAGGCTGAGCCTGTGCCACTGATCTGCCGGTGGACAGGATGCGACGAGGAGTTCCCGCATCAGCAGGCCTTTGTGGAGCACATCGAAAAGTGCCACGTGGACGTGAGGAAGGGCGAGGATTTCTCCTGCTTCTGGCTGGACTGTCCCAGGCGCTACAAGCCCTTCAATGCCCGCTACAAGCTGCTCATCCACATGCGCGTCCACAGTGGCGAGAAGCCCAACAAATGTCCGTTTCCCGGCTGCAATAAAGCATTTTCGCGTttggaaaatttgaaaattcatCAGCGCTCGCACACGGGCGAGCGGCCTTATGGCTGTCAGTATAAAGGCTGCCTCAAAGCGTTCAGCAATAGTTCGGATCGGGCGAAACATCAAAGGACGCACTACGACACGAAACCCTATGCCTGCCAGCTGCCCGGCTGCACCAAGCGCTACACGGATCCCTCCAGCCTACGCAAACATGTCAAGAACCACGCGCTGCGCAACGCCAACGGACAGCTGCGACGCAAGTCAGCCGGAGGAACCACGGTTCCGGCCGCAGGCGCTGGCGGAAGGAGGACGGCCAAAACCCGCCGCCACTCGGAGTCCGCCCTGGCACAGGTGCAGGTTCAGGTGCAGCAGACGGGAGCACCTGTACCTCCAGGTGCTGCAGGGGCAACGGGGGAACAGCGCCAGCAACGCAGCAATAGCTGTAGTGAGGCTTTGCTGCAGACAGACCGCAATGGCTGCGCCACTGGCGTGCCAGCTAATAACAATTCAATGAACTTTAATGAGTTGTCAAATTGCATTGTCATCATTGAGCACAATCGGAATGggccaacaacaacggcaaccgcagcaccaccaccagcagcagcagcagcatatgGCATCTAcgacggcagcaacaacatggCGTCCGCACCGGAAACGGATGCGCTGAGCGtttgcagcagcggcagccacaaCAATTACAATGGCTACGACGGTCATGgaaatattaatcaattaagCGAGCTCGAACAATTGCTGACGACGCCAAATGGCGTCTGCAAGCAGATTCCGGCTGCTAATGGGATTAGCTCCGCTGCCGCCACCGTCACCGCCGGCAACTGCAACTCCAACAACGGCAAATGCCAATTGAGCGAGTTTGTGTCGTTCGAGTACGTGACGAAATATCTCGCGGATGTGTACGAGCCGCCATCCGGCGCACAACGGCCCAAGAGCCCCAGTCCTGCGGCTAATTTCCATTTGCAGTCCGAGTTCGACAACAACTTCGACATGCTGGACTTTCAGCAGTTCATATGA
Protein Sequence: MSSTLKSLASQGGGMYVKTSDLGGISGKELPGSCFGGGFMSPPLSAKMVTDADRDIFRVPAKVDSVGHNNFSAGELQFPDFSHLCFAAETPNSVFSDCHAHLGQDQQQDSDQDHDQDDIVCAAAGNTSMPYQQGQYTQLNREDIFRFEPEDIARLTGESDLPGLLQPPQTPYTPYTPYTPYTPCSAQNSQPAASDSVNLDIDYFNYDEINCQSKNQSPCSSPPLDAWLNFNLGEISAAASGASPKLGNVFEEYVKEEQGQEPSPTKLPSMNSTFGTPKCIPMCASNYEDYSNLYQGSAYEAETYQHNLAQSVEKPNREHKVIWTIDELDELVLAEQQQFHQHQLRQQQEQHPQQEQLQCQSKNQDLTSYMADDLVKEEQYRNLDSEDEENYPEEDDDLDNEVFALPAESDPKPDSVCCDPEAETEAEPVPLICRWTGCDEEFPHQQAFVEHIEKCHVDVRKGEDFSCFWLDCPRRYKPFNARYKLLIHMRVHSGEKPNKCPFPGCNKAFSRLENLKIHQRSHTGERPYGCQYKGCLKAFSNSSDRAKHQRTHYDTKPYACQLPGCTKRYTDPSSLRKHVKNHALRNANGQLRRKSAGGTTVPAAGAGGRRTAKTRRHSESALAQVQVQVQQTGAPVPPGAAGATGEQRQQRSNSCSEALLQTDRNGCATGVPANNNSMNFNELSNCIVIIEHNRNGPTTTATAAPPPAAAAAYGIYDGSNNMASAPETDALSVCSSGSHNNYNGYDGHGNINQLSELEQLLTTPNGVCKQIPAANGISSAAATVTAGNCNSNNGKCQLSEFVSFEYVTKYLADVYEPPSGAQRPKSPSPAANFHLQSEFDNNFDMLDFQQFI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00594832;
90% Identity: iTF_00478293;
80% Identity: -