Basic Information

Insect: Drosophila seguyi
Gene Symbol: PRDM1
Assembly: GCA_008042675.1
Location: VNJU01003918.1:70801-75596[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 2.7e-05 0.002 18.4 2.5 1 23 927 949 927 949 0.99

2 5 8.2e-06 0.0006 20.0 5.1 1 23 955 977 955 977 0.98

3 5 1.7e-06 0.00012 22.2 4.3 1 23 983 1005 983 1005 0.98

4 5 0.00057 0.042 14.2 2.4 1 23 1011 1033 1011 1033 0.97

5 5 9.7e-05 0.0071 16.7 0.1 1 22 1039 1060 1039 1060 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	2.7e-05	0.002	18.4	2.5	1	23	927	949	927	949	0.99
2	5	8.2e-06	0.0006	20.0	5.1	1	23	955	977	955	977	0.98
3	5	1.7e-06	0.00012	22.2	4.3	1	23	983	1005	983	1005	0.98
4	5	0.00057	0.042	14.2	2.4	1	23	1011	1033	1011	1033	0.97
5	5	9.7e-05	0.0071	16.7	0.1	1	22	1039	1060	1039	1060	0.96

Sequence Information

Coding Sequence: ATGCACGGACACCACCACAATCACTCACAGAAtccgcaggagcagcagcagcagcagccgggagCCATCATGAAGCTGGGAAGCTCCTCTGGCCAGCCACACCATCCCGCCCACAGCCATCCACAACTCAACCATTCCCCGCATCCGCATCCCAACAACCATGCCCAGCCACATCCGCATTCACATCCCCATCCACATTCCCATGCGAATGTGCAtccacatccgcatccgcaccACAAGCTCTCAGCGAGAAGGGCGCGCAGTCGCAGTCGAAGTCGCAGCCCCACGCCGGATGGCAGCCAGGACTACGATGTGACCAGGATGCGGGAGGAGGACTTTGAGCGGCTGGCCGTCTATCTGGTGCCGGATGTGCAGGCGGAGCGGGGACTGCCCAATCGAGCGGACAAGACGCTGCCGCGCAGCCTCACGCTCAAGTCATCCATGGTCTACTCAACGCCAAATGTTAAGACTGAAGGAGTTTGGAGCAGCGGGGTCATCCCACGTGGCACTCGCTTCGGCCCATTCGAAGGCATTCCAACCTCAAACTATCCCAATGATAAGAATAAGGCGCGCTATTTCTGGCGGGTGCAGGGAACACGCCACATAACCTACGGGAATATTAAGATCTTCAAGGACGACGACTACTACTATCTGGATGGCTCGGATCGCTCGCAATCCAACTGGATGCGCTACGTGGCCTCCGCCTACAGTCTGTCCGTGATGAACCTGGTGGCGTGCCAGCACCAGGAGAACATCTACTTCTACACGACCCGCGACATCCTGCCCAACGAGGAGCTGATGGTGTGGTACTGCAAGGACTTCGCCAGTCGCCTCGGCTACGACGTCGATCCCGAGACGACCATCTTCGGCGCCTGCAAGCAGGCCGTTGAggccgaggaggaggtgatggacgaggaggaggaggaggcggagccggaggaggagggcgAGGCGGGAGTTGAGGGTGGCGGCAAGCGTCGCTATTCGATGCCCGCCCCCGAGATCCCAGCCGAGGTGGCCGTGAGTCACATCACCTACGTGATGGGTCTCCATCTGCCGGTGGGAGCGGCAAACGGTGGTCCAGCGAGTGGCTCCAcctcgccgccgccaccgacGCCGGCCGGGGGCCAGTGCTGCCGGAGAGCCAGCCCACCCTCCCATGTCAGCACCACCTCCTGCAACGCCCACCATCCGCACATCCAGCACGCCAGTCGCCATGCCTCGGTGATCATCGGCCAGGACCGCTCGCCGctgaccagcagcagcgacaaggACACGGCGGGATCGCCGCTGTCCGGCCTCGACCACCAGCTGACGCCGCAGGACGGCAGCGTGAGATCGGTGCGCTCGGACGAGGGCTACCACAGCAACGAGTGCCACGAGGATGGCCTCACGCCGCCCGAGGATTCCAGCGACAGCGAGAGCGAGCACAACTACGTGCTGGACTGCTCCAAGAAGGCCATCGCACCCAAGGAGACGGTGATTGCCCAGGCGCAGAAGCCGAGCAGCTCGCCACCGGCCGTGGTCATGGCCAATCccatcatcaccaccaccaccaccagcagcagtagtATTAGCCACAGCGCGGCCACGGCCACGGCATCCTGTGAGCCGGACAAGAACGAGTACCGCAAGTTCAAGGTGAAGATGCCGCTCAAGTACGAGTTCAAGAACAAGACCTGTGTGAAGCAGGAGCCCAGCCTCAAGGAGGTGGACCAGGAGATGTCGCTGCCCCaccacgaggaggaggaggagacggCGATGATGCACCAGGAGCCCGACTCCATTTGCCCCTCGACCACCACGCATCTGGGCGATGAGCATCTGATGATTATGGAGAGGGAACgcgagagggagagggaaCGGGAGCGGGAACGGGAGCGGGAGAGAGAGCCATCCAACCAGCAGCCCGCCTCCTCCACGGTTATCGTTCTGGAGCACAATTCCGGCGGCCAGGCCCGCACCATAGTGCCGCTGAGCAAGCCCTACTACGAGCCGGATCCGCCGGGCGAGCGCTACGTGCGCTTTGGCCAGCCCAGCTCCAGCATCCTGGAGACGATCCTCACCAGCCAGCACCGCttggaggcggcggcagcggcggccaaTGCCTGTCGGCAGGCCAACGCAGCCACGCCGCCGCCCACATCGCCCACGGAGATGGCCTACAGCTACAAGAAGTCGCAGCGGTATGGCAACGCCGTGAGTCCGGACAGCAGCTCGAATCTGGGCCAGAGtgccgagcagcagcagcagggagtGGGGGGCGTGGTCGTGGGCGGCGACCAGGACATGACCCGCGGCACCCTGATCAAGGGCGAGtgctcgccgccgccgccgagtcACCATCACCACAACGTGATCTTCTCGCCTTCGCGGCATCCGGCCTACCTGGGTGCCGGCGAGGTGGGCGGCCACTCGCCGAGTCCCGGCTATCCCGGGTATCCGCACTACGGAGCCGCCGCCACCTCCACCTTCCACTCGCCGCCGCACAGCTCGCACTCGCCCTTCGACCGGCAGTCAAATGCCTCGAGCGGAGCGGGTTCCGCCTCCAACTTGCATTTGCTGCAGAGCAGCACCCAGATGCTGAACCATCCGCTGATGCAGCCGCTCACTCCGCTGCAGCGCCTCTCCCCGCTGAGGATCTCGCCGCCGAGCAGCCTGAGTCCCGACGGCAACTCCTGCCCCAGGAGCGGCAGTCCCCTGAGTCCCAACTCCCTGGCCTCCAGGGGCTACCGATCGCTGCCCTATCCGCTGAAGAAGAAGGACGGCAAGATGCACTACGAGTGCAATGTGTGCTGCAAGACCTTCGGCCAGCTGAGCAACCTGAAGGTGCACCTGCGGACGCACTCGGGCGAGCGGCCCTTCAAGTGCAACGTGTGCACCAAGAGCTTCACCCAGCTGGCGCACCTGCAGAAGCACCACCTGGTGCACACCGGCGAGAAGCCGCACCAGTGCGACATCTGCAAGAAGCGCTTCTCGAGCACCTCCAACCTGAAGACGCACCTCCGGCTGCACAGCGGCCAGAAGCCCTATGCCTGCGATCTCTGTCCGCAGAAGTTCACCCAGTTTGTGCATCTCAAGCTCCACAAGCGCCTGCACACGAACGATCGGCCGTATGTGTGCCAGGGATGCGACAAGAAGTACATCAGTGCCTCGGGATTGAGGACGCACTGGAAGACCACCAGCTGCAAGCCGAACAatctggaggaggagctggccaTGGCGGCGGCAGCCACATCCGAGTGTCTGGATAAAGATCACCCTGAGCCGGACTCCCGCGAGGCCTacgagcaactgcagcagcacatGCATCCCGCTGTGCATCCCGGCCTAAGGCACTTGTCCGCCAGCGGCGGTCAGTCACCACCCCGCCTTATACCCCTGGGCAACCACATggcacaacagcagcagcagcagcaacagcagcaacaccaacagcagcagcattccCAACAGGGAGTGCCCCCACCGCCACCGCATCTGCTGATGGGACAGCATCCGGCTCCCATGCTCCTGACCACCGCCAGCCAGCTGCCTCCGCCGCTGCCCTCGCACCACCAGCAGTCCTCGCCCAGCCGCCTCCTCCAGCATGCCCATCCCCATGCACTCCagatccagcagcagcagcagcagcaacagcagcagcagcagcactcgcCCAAGGGACTCAAGTCCCTGCCAGAGTCGGCGGGGGTGTATCTGCACGGGGCGCATGTGCAGGCGCAGGAGAGCAGGCCCTCGGTCATCGAGTCCTCCAACCAGCCCATGATCATCGAGTGCACGTAG
Protein Sequence: MHGHHHNHSQNPQEQQQQQPGAIMKLGSSSGQPHHPAHSHPQLNHSPHPHPNNHAQPHPHSHPHPHSHANVHPHPHPHHKLSARRARSRSRSRSPTPDGSQDYDVTRMREEDFERLAVYLVPDVQAERGLPNRADKTLPRSLTLKSSMVYSTPNVKTEGVWSSGVIPRGTRFGPFEGIPTSNYPNDKNKARYFWRVQGTRHITYGNIKIFKDDDYYYLDGSDRSQSNWMRYVASAYSLSVMNLVACQHQENIYFYTTRDILPNEELMVWYCKDFASRLGYDVDPETTIFGACKQAVEAEEEVMDEEEEEAEPEEEGEAGVEGGGKRRYSMPAPEIPAEVAVSHITYVMGLHLPVGAANGGPASGSTSPPPPTPAGGQCCRRASPPSHVSTTSCNAHHPHIQHASRHASVIIGQDRSPLTSSSDKDTAGSPLSGLDHQLTPQDGSVRSVRSDEGYHSNECHEDGLTPPEDSSDSESEHNYVLDCSKKAIAPKETVIAQAQKPSSSPPAVVMANPIITTTTTSSSSISHSAATATASCEPDKNEYRKFKVKMPLKYEFKNKTCVKQEPSLKEVDQEMSLPHHEEEEETAMMHQEPDSICPSTTTHLGDEHLMIMEREREREREREREREREREPSNQQPASSTVIVLEHNSGGQARTIVPLSKPYYEPDPPGERYVRFGQPSSSILETILTSQHRLEAAAAAANACRQANAATPPPTSPTEMAYSYKKSQRYGNAVSPDSSSNLGQSAEQQQQGVGGVVVGGDQDMTRGTLIKGECSPPPPSHHHHNVIFSPSRHPAYLGAGEVGGHSPSPGYPGYPHYGAAATSTFHSPPHSSHSPFDRQSNASSGAGSASNLHLLQSSTQMLNHPLMQPLTPLQRLSPLRISPPSSLSPDGNSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDHPEPDSREAYEQLQQHMHPAVHPGLRHLSASGGQSPPRLIPLGNHMAQQQQQQQQQQHQQQQHSQQGVPPPPPHLLMGQHPAPMLLTTASQLPPPLPSHHQQSSPSRLLQHAHPHALQIQQQQQQQQQQQQHSPKGLKSLPESAGVYLHGAHVQAQESRPSVIESSNQPMIIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00609398;
90% Identity: iTF_00606569;
80% Identity: -