Basic Information

Insect: Drosophila seguyi
Gene Symbol: wdn
Assembly: GCA_008042675.1
Location: VNJU01003210.1:38348-41076[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 2.8e-05 0.002 18.4 0.5 1 23 312 334 312 334 0.99

2 7 0.049 3.6 8.2 1.8 2 23 345 365 344 365 0.93

3 7 5.3e-07 3.8e-05 23.8 1.1 1 23 371 393 371 393 0.99

4 7 3.3e-06 0.00024 21.3 4.0 1 23 399 421 399 421 0.98

5 7 0.00017 0.013 15.9 3.0 1 23 427 449 427 449 0.97

6 7 4.3e-06 0.00031 20.9 0.8 1 23 455 477 455 477 0.96

7 7 7.9e-05 0.0057 16.9 2.3 1 23 483 506 483 506 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	2.8e-05	0.002	18.4	0.5	1	23	312	334	312	334	0.99
2	7	0.049	3.6	8.2	1.8	2	23	345	365	344	365	0.93
3	7	5.3e-07	3.8e-05	23.8	1.1	1	23	371	393	371	393	0.99
4	7	3.3e-06	0.00024	21.3	4.0	1	23	399	421	399	421	0.98
5	7	0.00017	0.013	15.9	3.0	1	23	427	449	427	449	0.97
6	7	4.3e-06	0.00031	20.9	0.8	1	23	455	477	455	477	0.96
7	7	7.9e-05	0.0057	16.9	2.3	1	23	483	506	483	506	0.98

Sequence Information

Coding Sequence: ATGGAGTGCAAAGGCAAGGGCAAGAGAATGAAGGAAGAGGCGCCAAGCAAGAAGTTGCCGCCTAAAATCTATGGCGGCGATGCGGGCACCCCGACCAAGGCGGCCCACGACGAGATCCTCAGCTCCCTGCTGCGGATCAATAACTTCGACTCCATTTCGAGCATCAAGGACGAGTCGCTGGACATCGATCTGTCCGCCTGCGTGACAATTAGCTCCGCTAGCTTGGTCAACGGGAACAGCCTTTCCTCCACGGACTTCTGGCGTGTTCTCGACGAGAGCGCTCAAAACAACACGGAGCTCAACCTATCGTCGGATGGCGTCCGCGACGACCTGGCGGCCAGTGGCACCCTCGTGCCCAGCGGCAGTTTAACCAGTTCCAATGACAATCACTCCAGCTCAGAGTTCAATGTGACGTTCCTGCGGCCCGAGCCGCCGAACGCCTTCACCAACTCGCCCTTTAAAAAGACATCATCGAGCGGCGCCTCAACCCCAGTAAAGCTCTCCTCCGAGCAGCTGCATCTTcaccaacagcagctgcagatGCCCCAGCCGCTGGGCCAGCCAATGCAGCGCAAGCCCAAGCTGCCGGCGGTGACGGCGCTGCGCCTGAAGGTTTTTAAGGAAGAGCCGGCCGAGGAAAAACAACCCGTGACGGACGTAAAGTCGGCGCAAGTAGTGACAAAGGTTGAGGTGTGCGAAGGCGAGTTCCTGCCGCCATCGTTCACGATCTTTCAGCAGCCCCAGTTGGCTCGCACAGTGTCCCCGGAGGCAGATACGGCTAGCATGCCCCCGCCAGCTTCTGAGATCAACGGCAAGTCGTTGGAAGTTGATCCTGCTCCACTTCACAAGTGCCTCGATTGCAACGGCCTGCTGTTGGAGACCCCCGATGAGGTGACAAAGCATGAGGCGGCAGCACATCGGCTACGCCTAACCTACCGCTGCAGTGAGTGCCAGCGGGAATTCGAGGTGCTGGCAGGATTAAAGAAGCACCTCAAGACGCACCGCACCGAGGCTCGCAAGGACACTTGGAAGAAGTGCCCTGACTGCGGCAAATGCCTCAAGTTGGGCAGCATGTGGATGCATAGGAAGATTCACAGTGACAACAAGAAGTACCAGTGCGACATCTGCGGTCAGAAGTTCGTGCAGAAGATAAATCTTACACATCACGCCCGAATCCACTCCTCGGAGAAGCCGTACGAGTGTCCGGAGTGTCAAAAGCGCTTCCAGGAGCGATCGCATCTGCAGCGCCACCAGAAGTACCATGCCCAGACTCGTTCGTACCGCTGCGAGAAGTGCGGCAAAATGTACAAGACGGAGCGCTGCCTGAAGGTTCACAACCTGGTGCATTTGGAGCAGCGACCTTTCGCCTGCACGGTGTGCGACAAAAGCTTCATCAGCAACTCGAAGCTGAAACAGCACAGCAACATTCACACGGGCATGCGACCCTTTAAGTGCAACTACTGTCCACGCGACTTTACCAACTTCCCTAACTGGCTTAAGCACACGAGGCGCCGCCATAAGGTGGACCACAAAACAGGCGAGCACCTCGAGAACATTCCCTCCTACTGTTCAAAGAAGTCGACCACCAGTAAaaaagcagcggcagcagctgcggcgGTGGCAACAGCCACAGTGAATACCGACGATCTTGCCACTTCCAGTGATCTTAAAGTAAAGACCAATCCTGCACCGGCAGCTACCGTGGCACCTGCAAAACAGGCCCGGAAGAAaaagcagccgcagcaggctACACTGGCTGCCTTGGGGATAACCCTGCCAGCCGGCACAGCCCTTCAGCAGGTGCATCCGGCACCTTCAACAGCACAGCAGCAACCGGAATTGTCCTCTGTGGTGGTGACGCTGCCTCCGCCGGCGCCTAAGCAGGCCAAAGCTAAACGGGAACGTAAACAGTTGGCGCCCAAGCAACTACAACGACAGGCCCAGATGCAGCAAACCAATCCTGAGAATAACGCTGCAGTGGCGCAAATTAAAACTGAACCCGTGCAAAGCCAGGGTCCGTTTTTGGATTTGCATGGACTCAGTTTGACTTCAGCCGAGGAGCTAATCATGGAGCAGGCCCTGGAGATGGAGGAGTGCGGTCTATACGATGCTCCCGTCGTTCGCACAGACATGGGGACGTCGGACAACGCAATCTCTGACTCGGCAGCTGCCCTGCATTTCcagataaaaaatgaattaccTGACGAGTTGTTACCGGATGATGATTTTATGCCTTGTAAGCCCAGCGATCGCCTTGCTTGCCCCTCACTGGAGTCCTCACCGTTCTCTTCGCCGGCTTCCATGGAATTGACCGCTGTTTCCACCGCCTGCAGTACGGCCACAAACACGCAAGCTATACCAACGCGATCTGGGAACTACTATCTGCCTGCCTTCACACTAAACGCGAATGGCAAGCTAAGCGCAGGCAATTCGTCGCAGCCGGTGATCACGAGCGCTGTACCCACGGTGTCCATGGTGAATGTACCTATGCTAGTGCGCTCTAATCAGATGCTGCCCTCAGTGGACACACTGCTCTTCACCAACCAGACCGGCGGAAGTCGATTCTTTGCGGGGAAATCGACAACAGCGGCCACGCCGCATCTGACATGA
Protein Sequence: MECKGKGKRMKEEAPSKKLPPKIYGGDAGTPTKAAHDEILSSLLRINNFDSISSIKDESLDIDLSACVTISSASLVNGNSLSSTDFWRVLDESAQNNTELNLSSDGVRDDLAASGTLVPSGSLTSSNDNHSSSEFNVTFLRPEPPNAFTNSPFKKTSSSGASTPVKLSSEQLHLHQQQLQMPQPLGQPMQRKPKLPAVTALRLKVFKEEPAEEKQPVTDVKSAQVVTKVEVCEGEFLPPSFTIFQQPQLARTVSPEADTASMPPPASEINGKSLEVDPAPLHKCLDCNGLLLETPDEVTKHEAAAHRLRLTYRCSECQREFEVLAGLKKHLKTHRTEARKDTWKKCPDCGKCLKLGSMWMHRKIHSDNKKYQCDICGQKFVQKINLTHHARIHSSEKPYECPECQKRFQERSHLQRHQKYHAQTRSYRCEKCGKMYKTERCLKVHNLVHLEQRPFACTVCDKSFISNSKLKQHSNIHTGMRPFKCNYCPRDFTNFPNWLKHTRRRHKVDHKTGEHLENIPSYCSKKSTTSKKAAAAAAAVATATVNTDDLATSSDLKVKTNPAPAATVAPAKQARKKKQPQQATLAALGITLPAGTALQQVHPAPSTAQQQPELSSVVVTLPPPAPKQAKAKRERKQLAPKQLQRQAQMQQTNPENNAAVAQIKTEPVQSQGPFLDLHGLSLTSAEELIMEQALEMEECGLYDAPVVRTDMGTSDNAISDSAAALHFQIKNELPDELLPDDDFMPCKPSDRLACPSLESSPFSSPASMELTAVSTACSTATNTQAIPTRSGNYYLPAFTLNANGKLSAGNSSQPVITSAVPTVSMVNVPMLVRSNQMLPSVDTLLFTNQTGGSRFFAGKSTTAATPHLT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00565581;
90% Identity: iTF_00480387;
80% Identity: -