Basic Information

Insect: Drosophila seguyi
Gene Symbol: erm
Assembly: GCA_008042675.1
Location: VNJU01009400.1:76309-78225[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 1.5e-05 0.0011 19.3 0.8 1 20 342 361 342 364 0.93

2 6 7.5e-07 5.4e-05 23.3 1.6 1 23 370 392 370 392 0.97

3 6 5.9e-07 4.3e-05 23.6 2.5 1 23 398 420 398 420 0.98

4 6 7e-06 0.00051 20.3 3.2 1 23 426 448 426 448 0.98

5 6 0.0012 0.088 13.2 5.9 1 23 454 476 454 476 0.99

6 6 1.3e-05 0.00098 19.4 4.3 1 23 482 505 482 505 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	1.5e-05	0.0011	19.3	0.8	1	20	342	361	342	364	0.93
2	6	7.5e-07	5.4e-05	23.3	1.6	1	23	370	392	370	392	0.97
3	6	5.9e-07	4.3e-05	23.6	2.5	1	23	398	420	398	420	0.98
4	6	7e-06	0.00051	20.3	3.2	1	23	426	448	426	448	0.98
5	6	0.0012	0.088	13.2	5.9	1	23	454	476	454	476	0.99
6	6	1.3e-05	0.00098	19.4	4.3	1	23	482	505	482	505	0.98

Sequence Information

Coding Sequence: ATGCAACCGTGTAGTCCAGCGGGAGAAGTCGCAATGATGCCGCCGTCGAAGAGCCCCGTGATGGAGAGCGCCGCCTCCGACCAGAATCCGAGTCAGCAGAGTCAGCAGAGTCCGCCGAGCGGCGGTGATCAGAGTGCCGCCAAGCGGGCATGTCCCCTGAAGTTCTCCATAGCCAAGATTATGGAGCCGGATCACAGGCCCACTCAAGCagcgccaccaccaccacagcagccgccgccgcagcagcagcagcatcatgcCCACCCAGTGCAGGAGCCCctggtgctcatccaggaggacgaggacgatgagGATCCCGATATTGATGCGGACTCGGAGCGCTCCTGCAGTCCCATTGAGGTGATCAGCCTGGATCACTCGCCCTCCGCCGTTAATTACGATTCCGCCTTCAAGAAGTATGTGCCGGGGGCCTCCGCGGTGCCCAGTTCTTCGGCGGTTGGATCATCGCCGTCGAGCACGAGCAGTGCTGCTGTGCAGCAGTTCGTGAGCTCCCGCCACCAGGAGCTGCTCTCCCAGTATCCCCTGCTCTACTACGCCCCCAATCAGTTGATGTGCGCCGCAGCCGCCGCTCAGTATGCGGCCTTGACCGCCCAACAACAGTCCCTGGCCAGTGCCGCCCACCTGAGCAGCTTCACCGCCTCCCTGAACGCCACGCTGCATCACTCGCAGTCGCTGAGGAGGAACCTGGGGCATCCCctggcggcagcagctgcggcagcCGCCGTGGCCCAGTCCCAGGCTGTGCCCAGTAGCCTGCAACAGAGTCTGGAGAAGTCACCGGTGGCCCAGAGaacatcgtcgtcgtcgggtCAGTCCGGTGGACTGCCAGGCAACAATCTGAAGAGAAAGCGATCGCCACAGGATCAGGGTGAGGtgacaccaccaccaccgacgTCGGcggcagctggagcagccgctcgatcccgctcccgctccccaTCGCCGCAGGGATCCGTGGAGGACAGCAGCCCCGGATCGGCCAGCGGGGGCAAGCCCAAGACCTTCTCGTGCCTGGAGTGCGGCAAGGTGTTCAATGCCCACTACAATCTCACCCGCCACATGCCCGTCCATACCGGAGCCCGGCCCTTCGTGTGCAAGGTGTGCGGCAAGGGATTCCGGCAGGCCTCCACCCTCTGCCGGCACAAGATCATCCACACGTCGGAGAAGCCGCACAAGTGCCAGACGTGCGGCAAGGCCTTCAATCGATCCTCCACGCTGAACACCCACGCCCGAATCCACGCCGGCTACAAGCCATTCGTGTGCGAGTACTGCGGCAAGGGATTCCACCAGAAGGGCAACTACAAGAACCACAAGCTCACCCACTCCGGCGAGAAGGCGTACAAGTGCAGCATCTGCAACAAGGCCTTCCACCAGATCTACAACCTCACCTTCCACATGCACACGCACAACGACAAGAAACCGTACACCTGCCGGGTGTGCGCCAAGGGATTCTGCCGCAACTTCGACCTGAAGAAGCACATGCGCAAGCTGCACGAGATTGGCGGCGATCTGGATGACTTGGACATGCCGCCGTCCTTTGACAGGAGGCGGGAATATACGCGCCGGGAGCCGCTCTCCGCGGGCGGGTATGGTCAGGCCTCGGGCCAGCTGACGCCGGACTCCAGTTCTGGCAGTATGTCGCCGCCCATCAACGTGACCACTCCACCTCTGTCCAGTGCAGAGACGAGCAATCCAGCCTGGCCGCGTTCTTCTGCCCCGCATTATGCCGCTGGGGGATTCCATCACCTGGGTGTGGTGGCACCGCCACAGGACTATCCCAGCTCTGCCTTCCTGCAACTCCAGCCacagcaggcgcagcagccacATACCCAGCAGCATCcgcctcagcagcagcagcagaggctcTCGGAGACCTTCATTGCCAAGGTGTTTTGA
Protein Sequence: MQPCSPAGEVAMMPPSKSPVMESAASDQNPSQQSQQSPPSGGDQSAAKRACPLKFSIAKIMEPDHRPTQAAPPPPQQPPPQQQQHHAHPVQEPLVLIQEDEDDEDPDIDADSERSCSPIEVISLDHSPSAVNYDSAFKKYVPGASAVPSSSAVGSSPSSTSSAAVQQFVSSRHQELLSQYPLLYYAPNQLMCAAAAAQYAALTAQQQSLASAAHLSSFTASLNATLHHSQSLRRNLGHPLAAAAAAAAVAQSQAVPSSLQQSLEKSPVAQRTSSSSGQSGGLPGNNLKRKRSPQDQGEVTPPPPTSAAAGAAARSRSRSPSPQGSVEDSSPGSASGGKPKTFSCLECGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTSEKPHKCQTCGKAFNRSSTLNTHARIHAGYKPFVCEYCGKGFHQKGNYKNHKLTHSGEKAYKCSICNKAFHQIYNLTFHMHTHNDKKPYTCRVCAKGFCRNFDLKKHMRKLHEIGGDLDDLDMPPSFDRRREYTRREPLSAGGYGQASGQLTPDSSSGSMSPPINVTTPPLSSAETSNPAWPRSSAPHYAAGGFHHLGVVAPPQDYPSSAFLQLQPQQAQQPHTQQHPPQQQQQRLSETFIAKVF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548272;
90% Identity: iTF_00524594;
80% Identity: -