Basic Information

Insect: Drosophila seguyi
Gene Symbol: -
Assembly: GCA_008042675.1
Location: VNJU01002668.1:42544-48332[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 9.9e-08 7.2e-06 26.1 1.8 2 23 157 178 157 178 0.97

2 9 2.5e-07 1.8e-05 24.8 1.6 1 23 184 206 184 206 0.98

3 9 1.2e-07 8.4e-06 25.9 1.1 1 23 212 234 212 234 0.98

4 9 7e-07 5.1e-05 23.4 0.7 1 23 240 264 240 265 0.95

5 9 4.2e-05 0.003 17.8 3.1 1 23 270 292 270 292 0.97

6 9 0.00038 0.028 14.8 3.3 1 23 298 321 298 321 0.98

7 9 0.00036 0.026 14.9 1.9 1 23 327 349 327 349 0.99

8 9 3.9e-06 0.00029 21.0 0.8 1 23 354 376 354 376 0.98

9 9 0.004 0.29 11.6 0.3 2 23 383 407 382 407 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	9.9e-08	7.2e-06	26.1	1.8	2	23	157	178	157	178	0.97
2	9	2.5e-07	1.8e-05	24.8	1.6	1	23	184	206	184	206	0.98
3	9	1.2e-07	8.4e-06	25.9	1.1	1	23	212	234	212	234	0.98
4	9	7e-07	5.1e-05	23.4	0.7	1	23	240	264	240	265	0.95
5	9	4.2e-05	0.003	17.8	3.1	1	23	270	292	270	292	0.97
6	9	0.00038	0.028	14.8	3.3	1	23	298	321	298	321	0.98
7	9	0.00036	0.026	14.9	1.9	1	23	327	349	327	349	0.99
8	9	3.9e-06	0.00029	21.0	0.8	1	23	354	376	354	376	0.98
9	9	0.004	0.29	11.6	0.3	2	23	383	407	382	407	0.95

Sequence Information

Coding Sequence: ATGGACACCATCTGTAGATTATGCTTCCAAACGGCAACGCTCTTCCAGGTGCCCGGCTATAGCATACCCACGTGCGTCCGCTGCTCGGAACAGTTGACAAATAATTCCAACTTCCATCAatcggcagcggcggcggcggcagcgacgTCGACGCCCGCAGCGGCCGCCGTTGCCGCCTCGgctgccgcagctgctgccgctgcagcagcggccgccgctgccgcatCCTCGACGTCGACGGCCTCCTCCAGCGACAGCGACGCCGTCGCTCAGCTGACGAACGGTGGCGGCGGTAATAATGCCgccaacgccgccgccgctgctgccgtgCTGCAattgcagcatcagcatcagcaggcgcagcagcagcagcagcagcagcaacaaatgcaaTCATCGAGTTCTTCCGAGAATCTACAGTCGCAGGACGATTCCGAAGATGTGGATCTGATATTCAACGAGGAGGGCTCCTGCCCACTATGCAACAAGACTTTCTCGCGCAAATCCTCGCTCATGACGCACATACGGAATCACTCCGCGGAGCGTAAGTTTGTGTGCACCTACTGCCACAAAGGCTTCACGCAGGCGGCCAATCTGCGGAACCACGAGCGCATCCACACGAACGATCGTCCGTACCAGTGTGTGGATTGCGGCAAGACCTTTACCCAGATCACCAACCTGAACAATCATCGACGCCTGCACACTGGCGAGCGTCCGTTTGTCTGCAATGAACCAGAGTGTGGTCGCAGCTTCGCTCAGGTGACGAACCTGAACAATCACATGAAGTCGCACCACAAGGTGCAACAATATTGCTGCAACGTTTGCAACAAAAAGTTCACCCAGGTCACCTCTCTCAATCAGCATTTGCAGGCGCATGCCGGCGTCACCGGCTACTACTGCCCGCGCTGTCCGGAGAAGAACTTTAAGCTGCAGTCGCAGCTGCACACGCACATGAAGACGCACGGCCTGGCCTTTCCGTACGAGTGCAGCAAGTGCGACGAGAAGTTCCTGCAGCAGGCGCACCTCGATCAGCACCTCAAGATGCACGACgagttcaagttcaagtgcGACATCTGCCCGAGCAGCTTCAATCAGGAGTCGCTGCTAAAGAAGCATGTGCAGCGGCATGTCGAGGGCCGTTATCTCTCCTGTCCGGTGGCCAATTGTGCCGAATCGTTTGCCGTGCGCCAGCACCTGTCCAAGCATCTGTTAACCAGCCACTCGCATCACGAACTGCCGCCGCCGAAGCGCTCCAAGAAGACCGGGCACATGCAGTccgggcagcagcagccgctggcGATGATTGGTCAACCGCTGTCGCTGCAGCATACGACGGGGCAGCGTGGACGACCACcgaagaacaagaacaaggcTGCCTTGGCTGCCACGGCCATCAAGATTGAGATCAATGAGCCGCTCCACAGCCAGCATATCAGCAGTGCCAGCGGCCTGTCCATTCAGCAGCAGATCAATCAgcacatgcagcagcagcagcagcagcagcagcagcaacaacaggcgcaacagcaacagcaacagcagcagcagcagcaacagcatctgcatctgccGATGGGTCAGGCGGTCAAGGCGCGCTACATACCCACTAAGTAG
Protein Sequence: MDTICRLCFQTATLFQVPGYSIPTCVRCSEQLTNNSNFHQSAAAAAAATSTPAAAAVAASAAAAAAAAAAAAAAASSTSTASSSDSDAVAQLTNGGGGNNAANAAAAAAVLQLQHQHQQAQQQQQQQQQMQSSSSSENLQSQDDSEDVDLIFNEEGSCPLCNKTFSRKSSLMTHIRNHSAERKFVCTYCHKGFTQAANLRNHERIHTNDRPYQCVDCGKTFTQITNLNNHRRLHTGERPFVCNEPECGRSFAQVTNLNNHMKSHHKVQQYCCNVCNKKFTQVTSLNQHLQAHAGVTGYYCPRCPEKNFKLQSQLHTHMKTHGLAFPYECSKCDEKFLQQAHLDQHLKMHDEFKFKCDICPSSFNQESLLKKHVQRHVEGRYLSCPVANCAESFAVRQHLSKHLLTSHSHHELPPPKRSKKTGHMQSGQQQPLAMIGQPLSLQHTTGQRGRPPKNKNKAALAATAIKIEINEPLHSQHISSASGLSIQQQINQHMQQQQQQQQQQQQAQQQQQQQQQQQQHLHLPMGQAVKARYIPTK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00533229;
90% Identity: iTF_00609305;
80% Identity: -