Basic Information

Insect: Drosophila seguyi
Gene Symbol: zfh1
Assembly: GCA_008042675.1
Location: VNJU01002773.1:20470-24746[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.5e-05 0.0018 18.5 1.0 1 23 151 173 151 173 0.97

2 15 0.00077 0.056 13.8 1.2 3 23 181 201 179 201 0.94

3 15 0.00025 0.019 15.3 0.2 1 23 365 387 365 387 0.98

4 15 0.00013 0.0092 16.3 0.8 1 23 393 415 393 415 0.98

5 15 1.3e-05 0.00097 19.4 2.3 1 23 447 469 447 469 0.97

6 15 0.0094 0.69 10.4 1.2 1 23 503 525 503 525 0.93

7 15 0.0023 0.16 12.4 1.1 1 23 531 554 531 554 0.97

8 15 0.025 1.8 9.1 0.4 3 19 563 579 562 580 0.95

9 15 0.00015 0.011 16.1 5.6 1 23 589 611 589 611 0.97

10 15 0.043 3.2 8.3 0.4 2 23 617 638 616 638 0.96

11 15 8.6e-06 0.00062 20.0 1.0 1 23 647 669 647 669 0.98

12 15 0.00097 0.071 13.5 0.1 3 23 677 697 675 697 0.97

13 15 5.2e-05 0.0038 17.5 0.5 1 23 703 725 703 726 0.95

14 15 0.024 1.8 9.1 0.3 1 23 736 758 736 758 0.97

15 15 0.0051 0.37 11.2 0.2 1 23 1304 1326 1304 1326 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.5e-05	0.0018	18.5	1.0	1	23	151	173	151	173	0.97
2	15	0.00077	0.056	13.8	1.2	3	23	181	201	179	201	0.94
3	15	0.00025	0.019	15.3	0.2	1	23	365	387	365	387	0.98
4	15	0.00013	0.0092	16.3	0.8	1	23	393	415	393	415	0.98
5	15	1.3e-05	0.00097	19.4	2.3	1	23	447	469	447	469	0.97
6	15	0.0094	0.69	10.4	1.2	1	23	503	525	503	525	0.93
7	15	0.0023	0.16	12.4	1.1	1	23	531	554	531	554	0.97
8	15	0.025	1.8	9.1	0.4	3	19	563	579	562	580	0.95
9	15	0.00015	0.011	16.1	5.6	1	23	589	611	589	611	0.97
10	15	0.043	3.2	8.3	0.4	2	23	617	638	616	638	0.96
11	15	8.6e-06	0.00062	20.0	1.0	1	23	647	669	647	669	0.98
12	15	0.00097	0.071	13.5	0.1	3	23	677	697	675	697	0.97
13	15	5.2e-05	0.0038	17.5	0.5	1	23	703	725	703	726	0.95
14	15	0.024	1.8	9.1	0.3	1	23	736	758	736	758	0.97
15	15	0.0051	0.37	11.2	0.2	1	23	1304	1326	1304	1326	0.97

Sequence Information

Coding Sequence: ATGAACAACCAGGACTATGGCGGCATCCAGTGGATACAGCACCACCCCGCTGCAGGCGACTCTTCCGAGACGGACCTTCTGGAGCATGAAGACGGCGATGAAATGGTGAGCGGAGGGGACGGCGACCCAGACGGGGACGGGGATGCGGATGTTGACCTGGACCATATGGCTGCCGAGAACCTGATCTTTATGGCGCGCGACGGTCAGCTGGGAGAGATTATCGCCGCCAATGAGGGAACTGTCCTGGTCACCGCCGATGGCACGACGGTGGCGTATGCGGAATCCTTTGACGACGATGCCCAGGTGGTCACCGAGGAGGTCATCACCGACGACTGGGTGCAGCACCAGGGAGCCGAGCGCGTGGAAATCGCCGCTGAGCAAATAGCTGGGATTAGTAGTTCTCAGGAACTACTGGACATGGAGCAGGATGAGTACACGGCTTTGCGTCCCTATCCCTGCGATTTTTGCAGCCGGCGCTTTCGCAAGAAGGCCAGCTTGAACAACCACATGCTGGCCCACCAAAACGACCGACCTCATCTCTGCAAGCTGTGCGGAGCGCGCTTCTCACGCCGGGCGGAGCTCATTAGCCACTTTAAGGCCCACGCCGAAGCCCAGGATGCTGCGGATGCCgaggcagccgccgccgctgccgtttCGACCTCTTCCATAAAATTCGAGAATCAGGGCCAGAGGCAAATGGATGATCATTACTACGAGCAGGAGTGGCCGCTGtatcaacagcaacagcagcatgagcaggagcaggaacaggagcaagTGCATCATGAGCAAATGCTCCAACAGGAACAACAGCAACTAGTTTGCAACAGCGAGGTTCAGTTTGTGGCCAGCTACACAGCAACGGTGGCTCCTCCGCCTGCTCCGTCGCGCGGAAGGATTAGCAGGCTGAAACCCAAGGAGGAAAGCAGCCAGTTCATCGTAATTGCCGATAAGTCGACGTCCAGCGAGTTGCAGGACTACATGTCCAGTGAGACGGTGCCTCAGCCTATGATACCCACATCGCAGCCCATGGCCATTGATCCGCCGCCTGCTCCGAAGCCAAACTTCCCGGTGCTAGACGACAGCAAGCCCTTCGTGTGCCAGCAATGCGGATTGGCTTTTGCACGGGAGAAGGCGCTAGTCTCGCACACAAAGAATCATCGCGTGGACTCTCCCTTCGAGTGCAACCAGTGCCAGGAGATGTTCTGGGACAACAGCAGCCTGCAGGACCACCAAAAGACGCATCAGTTTGAGGAGAGCAATTCAGAGTATGATCCCGCCTCTGGCGATGATAGCGCCAGCGAAACATCGGAGCCGGAGGAACAACTCTACGGGGAGTTCTACTGCAACGAATGCGGCATCTCCTTTCATCGCCAGGATCTACTGCGACGTCATGCCAAGCAGCATTTCAAGCAGCAGGATCATAATTCAACGGTGGCGGCAGGAGACGGGAGCTCATCGGACATCATAGCTAGCGGGGATCAGGCCAAAGATGGTAACGGTGGACACTGCTGTCAAACGTGCGGAAAATCATTTCCCAGCGCCTTGGAGATGCTTTCCCATGCCGAAATTCATGCAAGGTTTCCGCCCTTCAAGTGCGTCCTTTGCGGCATAAGTTTTTCCGAGGAACAGGCCATCAAGCGGCATCTCCACACTCGCCACCCCAACGAACTGAAGGCCAACTCCTGCGTGCTGTGTGGCAAGGAGTGTCGCGATCGCAAGGCTCTGATCAAGCACGCCTGGGATCACTCCCGCGAAAAGTGTCACTCGTGCTCCAAGTGCGGCAAGAACTTTCATAATAAAGCGCGATTGAAGCGGCATATGGCCTCGCATCGTGACAAGTCCGTGGTCTGCGAGGTCTGCCAGGAGGAGTTTCCCGACGGCCGTACGCTGTCCAATCACCGACACTCGCACAGCACCACGTCGCCAGGAAAACTATTCCCCTGTCACGAATGCGGTAAGACATTTGGGTCACGCAGCTCCCAGCAGATCCACGTACGCATCCACACGGGTGAGCGACCCTACGGCTGCCGTTACTGCTGGAAGGCCTTCGCCGATGGAGGAACGTTGCGTAAGCACGAAAGGATTCATACGGGCGAAAAGCCCTACGCCTGCTCTGTCTGTCCGCGCGCCTTCAATCAGCGGGTGGTGCTGCGCGAGCACATCCGTTCCCACCACTCTGGGCTGGATGTGGCGAGAAATACGTACCACTGCACGGTCTGCTCCGAGGATCTGGCCACGTCTAATGACCTCATACAGCACCTCATCCAGCATAGTGACTCGAACACCGCCAAGCAGCGTCAACCAGTGACGGGACCACGAAAGTACAAGCGTCGACGCAAGCTGCAGCCTCACGAGATTGCGCACTTGCGGGCTGAGCACAAGGATGCaaacggcggcggcgacgagGAAGAGGTCCTGGGAGGCGAAGgggatggtgatggtgatggcgatggcgatggagaGGAATATGCTAGCGACATCGACCTTTGCGACTTTGACGTGGAGAATGTGGACGATCTCTTTGAAATGGCCGAGTCGTcgcccaaaaaagaaaaacgcaaGAGGGCATCGGCAGCGGCATCCGCGAAGACAGAACCAAAGCCTATTTCCAATGGCGGTGGGTTGTCGGTGAAGCCTGTCCAGGAGAAGAACAAGGCCAAGCTGCGATATGACTCTACCAGCAGTCAGCAATCAGATCGCATATGGGAGGAGAAATTTCTGCAGGACAGTCAGGTGGCGCTCTTCCAAATCGATTCGCTGGTGGTGGTCAACGATACTCACCTCCAACCAGCAAGCTCAGCAGCCATGCCCAAGACGAGAGGCGGCACcagacagcagcaacaacaggccAAACAACCCGTTGAAAGAGCTGGAAACTCAAATCCCTCGGCTGCAAGCTCACTTGCCACATCGTCAGCCTCCGCATCCGCCTCTACATCCACTTCGAGCAATCGAAGCAGAAAGAGGACGGCAGGCGTAAAGATGGCTGCTGCCACGCGACCCCGTATGATTCACACGGAAAAGGCCAAAGTGCCGTCCAAGGGAAATGCCGGTGGAGAGTTGGCCAAGAAGACACGATCCAAGACGTATATTACACGCACGGAGACGAGCAATCTGAGTAGTCTGGACAAGTCGCGAAGCAGAGCGTCCAACATCGTGGATGACTACGAAATCATTTCACCGGCTACCCATCCGCCCAACCAGATCAGCTCCAGTCCCCTGCACatcaagcaggagcaggagcagcagcaccgtGTCCAGATGATGTACGACGACAACCTCCTAATAGACGCTGCCCTGCTGCGGGAGAAGACCTACGAGAAGTTCAACCCGAGCATTGTGAACGATCTGGAGGAGATCCTGCGCTCGCCGCTCAAGCACGAACGCAACGCCCGCCTGCGATTCACCAGCGAATCCTCGACCACGCCCCAGTTTCTGCCCGAAGAAGAGCAGAATCTTATTAAGATTGAACCCACGTCTCCGGATTTGCGGGAGATGCTGGAGAGTCAGAGTCAAAGGGTCAGAGTACCAAGTGGCAACACACCGTCGCCCTCGTCTTCCTCAGCCAGAACTTCCCGTCATCGCATGATCACTGCCAGTGGACCAAGGGCAGGGAACAAGAGATCCGCAGGAGGAGGGGGAAGTGTTAGCAGCGCCAGCCAATCCTCACCTGTCCCAGGAGTGCCGGAAAAAAAAGTGAACACTGCGGCCAGTAAAGTCGGTAGCTCGTCCTCGTACCTCAATTATGGGGTGGATGCCTACAATGTAAACGTACCTGCCAGCGGCAGTACTGCCGATGTGGGCAGCGGATTTTTCTCCATCTCGGAGGTCGTGTCTGCCGCCGATGCAGCTGATGCGGCAGccaaggcggcggcggccggAAGGTCGGAGCGGAAAACGCGAAGTTTCGAGTGCGAAATGTGCTCGGCCATCTTTTATGATCGCGCTCAGTTACTGGAGCATGTGCACATCCACATCTAG
Protein Sequence: MNNQDYGGIQWIQHHPAAGDSSETDLLEHEDGDEMVSGGDGDPDGDGDADVDLDHMAAENLIFMARDGQLGEIIAANEGTVLVTADGTTVAYAESFDDDAQVVTEEVITDDWVQHQGAERVEIAAEQIAGISSSQELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAAAAVSTSSIKFENQGQRQMDDHYYEQEWPLYQQQQQHEQEQEQEQVHHEQMLQQEQQQLVCNSEVQFVASYTATVAPPPAPSRGRISRLKPKEESSQFIVIADKSTSSELQDYMSSETVPQPMIPTSQPMAIDPPPAPKPNFPVLDDSKPFVCQQCGLAFAREKALVSHTKNHRVDSPFECNQCQEMFWDNSSLQDHQKTHQFEESNSEYDPASGDDSASETSEPEEQLYGEFYCNECGISFHRQDLLRRHAKQHFKQQDHNSTVAAGDGSSSDIIASGDQAKDGNGGHCCQTCGKSFPSALEMLSHAEIHARFPPFKCVLCGISFSEEQAIKRHLHTRHPNELKANSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVARNTYHCTVCSEDLATSNDLIQHLIQHSDSNTAKQRQPVTGPRKYKRRRKLQPHEIAHLRAEHKDANGGGDEEEVLGGEGDGDGDGDGDGEEYASDIDLCDFDVENVDDLFEMAESSPKKEKRKRASAAASAKTEPKPISNGGGLSVKPVQEKNKAKLRYDSTSSQQSDRIWEEKFLQDSQVALFQIDSLVVVNDTHLQPASSAAMPKTRGGTRQQQQQAKQPVERAGNSNPSAASSLATSSASASASTSTSSNRSRKRTAGVKMAAATRPRMIHTEKAKVPSKGNAGGELAKKTRSKTYITRTETSNLSSLDKSRSRASNIVDDYEIISPATHPPNQISSSPLHIKQEQEQQHRVQMMYDDNLLIDAALLREKTYEKFNPSIVNDLEEILRSPLKHERNARLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMLESQSQRVRVPSGNTPSPSSSSARTSRHRMITASGPRAGNKRSAGGGGSVSSASQSSPVPGVPEKKVNTAASKVGSSSSYLNYGVDAYNVNVPASGSTADVGSGFFSISEVVSAADAADAAAKAAAAGRSERKTRSFECEMCSAIFYDRAQLLEHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00480304;
90% Identity: iTF_00617778;
80% Identity: -