Basic Information

Insect: Drosophila seclusa
Gene Symbol: -
Assembly: GCA_035043575.1
Location: JAWNMX010000134.1:428770-441816[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 1.1 72 4.1 2.0 3 23 299 321 297 321 0.92

2 14 1.5 93 3.8 0.5 3 20 462 479 460 480 0.95

3 14 1.1 69 4.2 0.4 2 23 506 528 505 528 0.87

4 14 0.04 2.6 8.7 0.6 1 23 545 568 545 568 0.95

5 14 0.28 18 6.0 0.2 1 21 573 593 573 597 0.91

6 14 0.016 1 9.9 0.2 2 23 651 673 650 673 0.95

7 14 0.51 32 5.2 0.1 1 21 678 698 678 699 0.92

8 14 0.0019 0.12 12.8 0.6 2 23 763 783 762 783 0.96

9 14 2.1e-05 0.0013 19.0 1.0 1 23 789 812 789 812 0.97

10 14 0.00025 0.016 15.6 0.7 1 23 838 860 838 860 0.98

11 14 1 66 4.2 0.6 1 23 867 891 867 891 0.95

12 14 1.7 1.1e+02 3.6 7.2 1 23 896 920 896 920 0.97

13 14 0.0046 0.29 11.6 4.1 1 23 933 955 933 955 0.98

14 14 0.0012 0.074 13.5 4.1 1 21 961 981 961 986 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	1.1	72	4.1	2.0	3	23	299	321	297	321	0.92
2	14	1.5	93	3.8	0.5	3	20	462	479	460	480	0.95
3	14	1.1	69	4.2	0.4	2	23	506	528	505	528	0.87
4	14	0.04	2.6	8.7	0.6	1	23	545	568	545	568	0.95
5	14	0.28	18	6.0	0.2	1	21	573	593	573	597	0.91
6	14	0.016	1	9.9	0.2	2	23	651	673	650	673	0.95
7	14	0.51	32	5.2	0.1	1	21	678	698	678	699	0.92
8	14	0.0019	0.12	12.8	0.6	2	23	763	783	762	783	0.96
9	14	2.1e-05	0.0013	19.0	1.0	1	23	789	812	789	812	0.97
10	14	0.00025	0.016	15.6	0.7	1	23	838	860	838	860	0.98
11	14	1	66	4.2	0.6	1	23	867	891	867	891	0.95
12	14	1.7	1.1e+02	3.6	7.2	1	23	896	920	896	920	0.97
13	14	0.0046	0.29	11.6	4.1	1	23	933	955	933	955	0.98
14	14	0.0012	0.074	13.5	4.1	1	21	961	981	961	986	0.93

Sequence Information

Coding Sequence: ATGAACGGCGAGTCGGCAGATCAGGAGGACACTCATTTGTGCATCAAATGCAATGCGACAATTGTGGGTCTGGACAAGTACATTGAGCACCGTAAACAGAATTGCCGCAGCACTGGCGGCAATGAGCACCTCCCGAAGCAAGTGGTGACTCCGACAACGACGTCGGCTCCCACCGAGCAAGTATCGCACCCAAGCACCCACACCTACGATGGCTTCCACTTTGCAGAGCCGGAGGCACCCAGCAGTTATCTGCGCAAAACGGCCTCCAGTCATGGCGGAAAGACGTCCAAGTCCCTAACGGACTCCTATGATCCGACCTACGACCTGGGCGCAGATCTGTTCTTCTcatcgctgcagctgcaaagtGTCTCAACTGGCGGCAAAACAGGCGCACGGCCGGAGCGAGGCGCCAAGGAGGATCAGAGCTGGCATTCGTCCAGCAACTGCTCCGATCCGCTGCTGAAAGCGGTCCGGGAACACGAGGTAACCCACTTTAAGTCACTCAAATTTGTGCACTCGCCAGAGGCAAGCGAGgaggatgacgacgacgaggacttcgatgatgatgagcatgAACATGAGCATGAACATGAGCATGAACATGATCCCGATCAAGATCCCGAGCCTGATGAAGATTACGATGGTCGTCGCCATTCGCCGCCAACGGTGCCTGCGACGCACACGGGTGGCAAATGGAAGCCGGAACATCGTCCGCAACTGCAACATACGCACCTGGAACGCATCTCGCCCAGCTGGGATGAGCCGCCCGAGGAGCAGCACGATCATCCGCCGGCGGAGCACACGCACGGCAAATGGGTGCCGggcagcaagcagctggaGTATCGCGAAAACATCGATCTGaccaagctgcagcagccaggcGCCAGCTACTGGTGCAACATCTGCTGTCGTCGCCTCAAGACGCGCATCAACTACGAGCAACATTTGCGCAGCGCCTACCATCAGCGACGCGCCGATGCCGAGCGTCAGCTGGAGCAGGCCACTCTGGCAAGCGCCAATCTAACACTAACCACCAAGGACCTCCCACAGACGCCGCCGACGGAGCAGCTGCCGCGGCGTCGCCGGCGTCGTGCCCATTTTCTGCGCTGCGATCTGTGCCGGCACAGCATGGGCCGCCATCTGATGGGCAAGCATCTCATCTCCCACTATCACTATCGccgcctgcagcagcagcagccaagccaACTGCGGCGGCAGAGCTCCCTGCACGCCATCCTCGAGCACATGGGCAGCATTGTTAGACAGGCGCCGTTCCAGTGTCTACCCTGTCGCTTCTATGCCAACACTGAGCAATCTTTTCagCTCCATTGGCGCTCCTCGACGCATGTGAAGCTGACGGAGAGACTTGGTGGCAGCTTCTGGTGCAGCTACTGCCAGTTCGAGTGTGCCAGCAATGAAGAGAtgtggcaacatttgctgtgCTCCTCGCACAAGGGGGTGCTCTTTGCGATCAATCGTTCGGTGCCCGTTTGCATTGCCCAGCGTCGTCCACTGAGCTGTTCCAGCTGCAGCGCCACTTTCCTGTACAATGCGCAACTGCGTCGTCACTTCGCCGAGGAGCATGTGGGCTTGGTGGCAACGGGCACCGCTGCCGATGACTATCAGTGTCGCTACCGCTGTGGGATTTGCGGCGTCGCACAGAGATCTCGAGTGGCGTTGCAGCGGCACGAGAAGCACAAGCATCGATTGGCCAAATACTACTGTGCCGTTTGCCGGCTGGATTTCGAGACGCCGCAGGAGGCGCGACGCCATCGCAGTCTGATGCAGCACAAGCGGCAAGCTTGCCGCCAACTGAGccgcaaatgcagcagcagcagtagcagcactAATCAGCCTGATCGCGAGATTCAACACATGCTGCACAAGGtgctggaggagcagcagtcagcagcagcggatgAGCTGGCCACGAGGCGTCGCCTGGATAGCCAGTGTGTCAGCTGTTCGCTTAGCTTTGAGACGCCCCAGGCACTCGTCCAGCATCGTCGCGAGTCGCATCCCATGGACAATCATGCCTGTCTCAGCTGTGGGAGTAGCTTTCAGTCCGCCCAGGCTCTGGGAAGACACACACGCGGCTGCCAGCCCACAGCGTCCACCtcgacagctgctgctcctgctgatccagcttcagctccagctgcaacaTCTCAATCAAAGTCCTGGAATTGTGCGCAGTGCAGTTTCACTGCTCAATACGAATCGGATTTGATCTATCATCGCTTCTTTCACACCCACGGGTCGGCAATTGGCAAGAATGAGCTGCTCCAGTgtccgctgtgccccaaacaGTTTCGCAAGGACTCACTGCGTCCGCATCTGCGCAATCATACGAACGAAAGGATCTTCGAGTGCGTCGAGTGCCCGGCCAAGTTTGTACGAAGACACAACCTCAAGAATCACATCGCCACAAAGCATGGCCAAAAGGAGAAaacatcagcagctgctgataaGCCAACAGTCAAGCAATCGAAAGATGCTGCAAAGCGGAAATATCAATGTAGCACCTGTGACAAAATACTGGCGAAAAAatACTCACTCAAAATACACGAAATGAGCCACGCTGAGGCGGAGCGTCAACATCGTTGCCACATTGAGGATTGTCAATATGCGGGTCTCACGCCGGAGGCACTCAAGACCCATCTAATCTCACATGCGAAAGGAgaacacaaatgcaaacacgAAAACTGCCGATATGTGGGCAAAAGTGAGCTGCATCTGAAGAGGCACCTCAAGTCGCATGTGCCCGAAAAGGAGCTGGTCGAGGCTGGCAAATGGTTTTCGTGCGATCAGTGCAAGTTCAGGGCCCGCATCAGAGGACATCTGAGGCGGCACATGCGTCGCCACACTGGCGAGAAACCCCATCAGTGTCCGCACTGTGACTTCCAGTGCAGCACCATAGATAATCTGCGCAAGCATATCATCAAAACGGGCAAGCATCCTGGCAAGTTCATCTACGAGTGTTCGTCCTGCGACGCCTTCAAGAGCAACAGCTTCAAGGATCATCAACTGCATTTGGCCACGCATAAAAACGAATTGCCCTAA
Protein Sequence: MNGESADQEDTHLCIKCNATIVGLDKYIEHRKQNCRSTGGNEHLPKQVVTPTTTSAPTEQVSHPSTHTYDGFHFAEPEAPSSYLRKTASSHGGKTSKSLTDSYDPTYDLGADLFFSSLQLQSVSTGGKTGARPERGAKEDQSWHSSSNCSDPLLKAVREHEVTHFKSLKFVHSPEASEEDDDDEDFDDDEHEHEHEHEHEHDPDQDPEPDEDYDGRRHSPPTVPATHTGGKWKPEHRPQLQHTHLERISPSWDEPPEEQHDHPPAEHTHGKWVPGSKQLEYRENIDLTKLQQPGASYWCNICCRRLKTRINYEQHLRSAYHQRRADAERQLEQATLASANLTLTTKDLPQTPPTEQLPRRRRRRAHFLRCDLCRHSMGRHLMGKHLISHYHYRRLQQQQPSQLRRQSSLHAILEHMGSIVRQAPFQCLPCRFYANTEQSFQLHWRSSTHVKLTERLGGSFWCSYCQFECASNEEMWQHLLCSSHKGVLFAINRSVPVCIAQRRPLSCSSCSATFLYNAQLRRHFAEEHVGLVATGTAADDYQCRYRCGICGVAQRSRVALQRHEKHKHRLAKYYCAVCRLDFETPQEARRHRSLMQHKRQACRQLSRKCSSSSSSTNQPDREIQHMLHKVLEEQQSAAADELATRRRLDSQCVSCSLSFETPQALVQHRRESHPMDNHACLSCGSSFQSAQALGRHTRGCQPTASTSTAAAPADPASAPAATSQSKSWNCAQCSFTAQYESDLIYHRFFHTHGSAIGKNELLQCPLCPKQFRKDSLRPHLRNHTNERIFECVECPAKFVRRHNLKNHIATKHGQKEKTSAAADKPTVKQSKDAAKRKYQCSTCDKILAKKYSLKIHEMSHAEAERQHRCHIEDCQYAGLTPEALKTHLISHAKGEHKCKHENCRYVGKSELHLKRHLKSHVPEKELVEAGKWFSCDQCKFRARIRGHLRRHMRRHTGEKPHQCPHCDFQCSTIDNLRKHIIKTGKHPGKFIYECSSCDAFKSNSFKDHQLHLATHKNELP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00528388;
90% Identity: iTF_00482583;
80% Identity: -