Dsec010086.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila seclusa
Gene Symbol
-
Assembly
GCA_035043575.1
Location
JAWNMX010000522.1:6707332-6711912[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 2.2e-05 0.0014 18.9 5.5 1 23 20 42 20 42 0.98
2 16 0.00015 0.0099 16.3 5.1 1 23 48 70 48 70 0.98
3 16 8.3e-05 0.0053 17.1 2.1 1 23 76 98 76 98 0.98
4 16 4.3e-05 0.0028 18.0 2.6 1 23 104 126 104 126 0.99
5 16 2.5e-05 0.0016 18.8 0.4 1 23 132 154 132 154 0.97
6 16 2.3e-05 0.0014 18.9 0.2 1 23 160 182 160 182 0.98
7 16 1.1e-06 7.3e-05 23.0 3.2 1 23 188 210 188 210 0.98
8 16 0.003 0.19 12.2 0.6 1 23 216 238 216 238 0.97
9 16 2.2e-05 0.0014 18.9 5.5 1 23 484 506 484 506 0.98
10 16 0.00015 0.0099 16.3 5.1 1 23 512 534 512 534 0.98
11 16 6.2e-05 0.004 17.5 5.8 1 23 540 562 540 562 0.98
12 16 4.3e-05 0.0028 18.0 2.6 1 23 568 590 568 590 0.99
13 16 2.5e-05 0.0016 18.8 0.4 1 23 596 618 596 618 0.97
14 16 2.3e-05 0.0014 18.9 0.2 1 23 624 646 624 646 0.98
15 16 3.1e-06 0.0002 21.6 4.3 1 23 652 674 652 674 0.98
16 16 5.9e-05 0.0038 17.6 0.6 1 23 680 702 680 702 0.99

Sequence Information

Coding Sequence
ATGGCCGATGGGGAATCGCTACAGGTTGTTCCTGCACCTGGCGGCGAGGTCCTGCCCCATGTATGTAATGTGTGCAACAAAGCGTTTCGACAGCAGTGTCGTCTCAATCAGCATATGCGCTCCCATGTGGACGAGAAACTGCACAAGTGTGAGGTGTGTGGAAAGAAGTTGAAACACTTGCGGAACTATAAGGAGCACATGCTGACGCATACCAAAGCTAAGCCGCATAAGTGTATGGTGTGTGCACGCTTCTATCGCACCACGTCCAGCTTGGCTGCCCACATGCGCACGCATGCCAAGGACAAACCGTACAAGTGTGATCAGTGCGGACGCAGCTATGCGGCCTTCGATCATCTGCGACGGCACAAGCTGACGCACACCGGCGAGCGTCCGTATGCGTGCGATCTGTGTGATAAGGCTTACTATGATTCGTCGTCGCTGCGACAGCACAAGATTAGCCATACGGGCGAGAAGGCGTTCACCTGCGAAATCTGCGGCGTTGGCCTCTCACAGAAATCGGGCTATAAGAAGCACATGCTGGTGCATTCCGGCGAAAAGCCGCACAAATGCCACATCTGTGGGCGAGCCTTCACCTTCACCAGCAATCTAAACGCCCATGTCCGACTGCACTCCGGCGAGAAGCCATTCAAGTGCGACAAATGCATCAAGGCATTCCCAACGAAAAAGCGCCTAATTAGCCACCAAGGTGTGCACAACAAGGAGGCGCCCGTCACGACAACCAGCAACATTGTCAGACCCGGCTCCAATGGACAGTCGGATCGGGCCGCACTTTTTGCAGCCGGTCGTCGGGCAGCCATCAATAGGACCGATGGCATGGATCATCAGCTGTCCACATCCAAGGATGGCGCCTCGATGCCCCAGCACATTTGCATGCTTTGCCTGCAGCTGTTAGAGCAGGCGTTTAATTTTAAGCGGATGGTCATCGATTCCGATGAACTGCTCCGTATAGGCCTCGAGGAAGTCGAGAGCACGTCAAGTTCCAATGAACATCCCAATGACAAATCTGTGGCCGAAACGAATGCCGCAACGCTTGTTGAGGCGTGCTATGAACAGAAAAAGGATATGGAAGCAGAGGCGGAACaatatgaatttattgttGATAATCCGGATTTGGATGCATATGTTGAGACAGAGGATGCACTTGATTTGCAAACGACAGACTTTGAGTATGTGACAATCAAATCAGAATACGACTCGCAAGTTGAGGACGATGATGACATCGAGATTGTGGACTCGACCGGCCTCGAAACGGTCAGCGATCAAATGGAAATTCAAATGCTTGACGAGCACATGGTTATTTTGTCTGGCGAGGAGCACATCGATGAGctAACTGGCGGTAGCGAGGAGTGTGATGAATTTCTGGATGAGTCAATGGCCGATGGGGAATCGCTACAGGTTGTTCCTGCACCTGGCGGCGAGGTCCTGCCCCATGTATGTAATGTGTGCAACAAAGCGTTTCGACAGCAGTGTCGTCTCAATCAGCATATGCGCTCCCATGTGGACGAGAAACTGCACAAGTGTGAGGTGTGTGGAAAGAAGCTGAAACACTTGCGGAATTATAAGGAGCACATGCTGACGCATACCAAAGCTAAGCCGCATAAGTGTAAGGTGTGTTCACGCTTCTATTGCACCACGTCCAGCTTGGCTGCCCACATGCGCACGCATGCCAAGGACAAACCGTACAAGTGTGATCAGTGCGGACGCAGCTATGCAGCCTTCGATCATCTGCGACGGCACAAGCTGACGCACACCGGCGAGCGTCCGTATGCGTGCGATCTGTGTGATAAGGCTTACTATGATTCGTCGTCGCTGCGACAGCACAAGATTAGCCATACGGGCGAGAAGGCGTTCACCTGCGAAATCTGCGGCGTTGGCCTCTCACAGAAATCGGGCTATAAGAAGCACATGCTGGTGCATTCCGGCGAAAAGCCGCACAAATGCCACATCTGTGGGCGAGCCTTCACCTTCACCAGCAATCTAAACACCCATGTGCGACTGCACTCCGGCGAGAAGCCATTCAAGTGCGACAAATGCATCAAGGCATTTCCAACGAAAAAGGGCCTCATTAGTCATCAGCGTGTGCACAACAAGGAGGCGCCCGTCACGACAACCAGCAACATTGTCAGACCCGGCTCCAATGGACAGTCGGAACGGGCCGCACTGGTTGCAGCCGGCCGTCGGGCAGCCATCAATAGGACCGATGGCATGGATCATCAGCTGTCCACATCCAAGGTAGTCGTGGTTCTATAA
Protein Sequence
MADGESLQVVPAPGGEVLPHVCNVCNKAFRQQCRLNQHMRSHVDEKLHKCEVCGKKLKHLRNYKEHMLTHTKAKPHKCMVCARFYRTTSSLAAHMRTHAKDKPYKCDQCGRSYAAFDHLRRHKLTHTGERPYACDLCDKAYYDSSSLRQHKISHTGEKAFTCEICGVGLSQKSGYKKHMLVHSGEKPHKCHICGRAFTFTSNLNAHVRLHSGEKPFKCDKCIKAFPTKKRLISHQGVHNKEAPVTTTSNIVRPGSNGQSDRAALFAAGRRAAINRTDGMDHQLSTSKDGASMPQHICMLCLQLLEQAFNFKRMVIDSDELLRIGLEEVESTSSSNEHPNDKSVAETNAATLVEACYEQKKDMEAEAEQYEFIVDNPDLDAYVETEDALDLQTTDFEYVTIKSEYDSQVEDDDDIEIVDSTGLETVSDQMEIQMLDEHMVILSGEEHIDELTGGSEECDEFLDESMADGESLQVVPAPGGEVLPHVCNVCNKAFRQQCRLNQHMRSHVDEKLHKCEVCGKKLKHLRNYKEHMLTHTKAKPHKCKVCSRFYCTTSSLAAHMRTHAKDKPYKCDQCGRSYAAFDHLRRHKLTHTGERPYACDLCDKAYYDSSSLRQHKISHTGEKAFTCEICGVGLSQKSGYKKHMLVHSGEKPHKCHICGRAFTFTSNLNTHVRLHSGEKPFKCDKCIKAFPTKKGLISHQRVHNKEAPVTTTSNIVRPGSNGQSERAALVAAGRRAAINRTDGMDHQLSTSKVVVVL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-