Dsec000973.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila sechellia
Gene Symbol
-
Assembly
GCA_004382195.1
Location
NC:16088495-16090392[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 2.1e-06 0.00013 21.8 1.6 1 23 82 104 82 104 0.98
2 15 6e-05 0.0038 17.3 6.3 1 23 110 132 110 132 0.98
3 15 7.3e-05 0.0046 17.0 3.1 1 23 137 159 137 159 0.97
4 15 6.8e-07 4.3e-05 23.4 2.0 1 23 165 187 165 187 0.99
5 15 1.7e-07 1.1e-05 25.2 5.6 1 23 193 215 193 215 0.99
6 15 0.00014 0.0089 16.1 4.9 1 23 221 243 221 243 0.99
7 15 7.7e-06 0.00048 20.1 0.7 1 23 248 270 248 270 0.99
8 15 6.8e-06 0.00043 20.2 1.9 1 23 276 298 276 298 0.97
9 15 6.4e-05 0.004 17.2 0.8 2 23 305 326 304 326 0.97
10 15 7.3e-05 0.0046 17.0 3.3 1 23 332 354 332 354 0.98
11 15 0.082 5.2 7.4 7.8 1 23 360 382 360 382 0.97
12 15 0.00015 0.0096 16.0 2.6 2 23 389 410 389 410 0.97
13 15 7.6e-07 4.8e-05 23.2 5.3 1 23 416 438 416 438 0.99
14 15 0.00052 0.033 14.3 4.1 1 23 444 466 444 466 0.99
15 15 0.12 7.6 6.8 1.7 9 23 480 495 472 495 0.88

Sequence Information

Coding Sequence
ATGGATCTGACGAACGTAGATCAAGGCCTCGTGAAGAACGACCCAACACAAGAAGACACTTTCGAGGAAGAATTAATCTTCATTTCTAACAGCGACTTCGAAGAGCTCGAAAACGAAATAAAGATTGAGGAATCCTGTTTTTATGACAAAGATTTGGAGCCAGTTAAAAGCGTCCCGTCGAAGCTGAAGACATGTAAATCCACAATAGCAGAGAAGCGCCTCTTGCGAAAGCGAACAGAGTCGTTTAAGTGTACCCAATGCCAAATGGCGTttacaaaaaaggaaaacctcGAATCACACTTGCGACTTCACGCAGAAGAACGTCCGTTCGAGTGCTCCCAGTGCTCCAAGAGCTTTAGACGCAGGTTGCATTACAAGCGACACTTGCTCAAACACGAGAAGCGACCTCATAGGTGTTCCAACTGTGCAAAGACCTTTACCCAGGATTCATCGCTTAAACAACATCAGCTTGAGCACACTGGAGAGCGGCACTTCAAGTGTTCCCAGTGCGCAACGTCGTTTGCGCGAAAATCGTATCTTAAGGTACACTTACGTACGCACAGTGAAGAACGACCCTTTGAGTGTACCCATTGCGAAAAGGCATTTAAAAGCAGTTCGCATCTTAAGGATCACTTGCGAACTCATAAGGAGGGACGGCCCTTTAAGTGTTCCCACTGCTCGAAGAGTTTTAAACTCAGGTCAATTCTACAAAAGCACTTGCTGACGCACGCCGAACGATCCTTTAAGTGTACCCAGTGCCCGAAGACTTTTCTTCAGAATGATGGTTTGCAAATTCATTTGCGAATGCACGCGGGCGAAGACCCGTTCAAGTGTTCCCATTGCTCAGAGACCTTTGCAAAGAATTCGAGTCTTCAACTACACATACTTGAGCACGCAGGAAAAGAGCCCCTTAAGTGTTCCCAGTGCTCAGCCACCTTTGCCACGAGGTCACTTTACCGAGTCCACGTGCGTTCGCATACAAGAGAGCGGCAGTTTAAGTGCGACGAATGCTCGAAATCTTTCTTCAAGAAGTCACATATTGTCGAGCATCAGCAAGTGCATACGGGAGAGCGACCCTTTAAGTGTGCCCACTGCTCCAAGGACTTCAAATGTCGTACGCATCTTCGGGTGCATTTGCTTGATCATTCTGGAGAAAAGCCCCCCAAGTGTTCCCACTGCTCGAAGGAATTTAAGCTAAGCTCGCAACTGCTGGTGCACCTGCAAGAGCATACTGGAAAAAACCACTTCGAGTGTCCCCACTGCTCGAAGTCCTATACAACCAGCTCGTCTCTTCATATGCACTTGCGAACGCACACGGGAGAATTGCCCTTCAAGTGTTCCCACTGCTCCAAGGAGTTTGCGAGAAGCGCAGACCACGAGGAACACTTGCGAACGCATACGGGTGAAAAACCCTTCAAGTGTTCACACTACTCAGCCAGATACACACAGAAGTCCAGTCTTGGGCGGCACCTGCGGACAAACcactaa
Protein Sequence
MDLTNVDQGLVKNDPTQEDTFEEELIFISNSDFEELENEIKIEESCFYDKDLEPVKSVPSKLKTCKSTIAEKRLLRKRTESFKCTQCQMAFTKKENLESHLRLHAEERPFECSQCSKSFRRRLHYKRHLLKHEKRPHRCSNCAKTFTQDSSLKQHQLEHTGERHFKCSQCATSFARKSYLKVHLRTHSEERPFECTHCEKAFKSSSHLKDHLRTHKEGRPFKCSHCSKSFKLRSILQKHLLTHAERSFKCTQCPKTFLQNDGLQIHLRMHAGEDPFKCSHCSETFAKNSSLQLHILEHAGKEPLKCSQCSATFATRSLYRVHVRSHTRERQFKCDECSKSFFKKSHIVEHQQVHTGERPFKCAHCSKDFKCRTHLRVHLLDHSGEKPPKCSHCSKEFKLSSQLLVHLQEHTGKNHFECPHCSKSYTTSSSLHMHLRTHTGELPFKCSHCSKEFARSADHEEHLRTHTGEKPFKCSHYSARYTQKSSLGRHLRTNH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00539787; iTF_00596781;
90% Identity
iTF_00539787; iTF_00596781;
80% Identity
-