Basic Information

Insect: Drosophila santomea
Gene Symbol: -
Assembly: GCA_016746245.1
Location: NC:16779655-16795176[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.00065 0.041 14.0 0.6 2 23 239 261 238 261 0.94

2 10 0.01 0.66 10.2 4.6 2 23 374 396 374 396 0.91

3 10 0.0051 0.32 11.2 2.3 3 23 470 491 468 491 0.94

4 10 0.55 35 4.8 2.3 1 19 591 609 591 614 0.93

5 10 0.011 0.71 10.1 0.4 2 23 722 744 721 744 0.96

6 10 0.00058 0.037 14.1 0.2 2 23 794 816 793 816 0.92

7 10 0.008 0.51 10.5 3.6 2 23 866 888 865 888 0.96

8 10 1.5 96 3.4 0.8 2 16 902 916 901 918 0.87

9 10 0.0016 0.1 12.7 0.7 2 23 986 1008 986 1008 0.95

10 10 0.036 2.3 8.5 0.6 1 23 1102 1124 1102 1124 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.00065	0.041	14.0	0.6	2	23	239	261	238	261	0.94
2	10	0.01	0.66	10.2	4.6	2	23	374	396	374	396	0.91
3	10	0.0051	0.32	11.2	2.3	3	23	470	491	468	491	0.94
4	10	0.55	35	4.8	2.3	1	19	591	609	591	614	0.93
5	10	0.011	0.71	10.1	0.4	2	23	722	744	721	744	0.96
6	10	0.00058	0.037	14.1	0.2	2	23	794	816	793	816	0.92
7	10	0.008	0.51	10.5	3.6	2	23	866	888	865	888	0.96
8	10	1.5	96	3.4	0.8	2	16	902	916	901	918	0.87
9	10	0.0016	0.1	12.7	0.7	2	23	986	1008	986	1008	0.95
10	10	0.036	2.3	8.5	0.6	1	23	1102	1124	1102	1124	0.99

Sequence Information

Coding Sequence: ATGGCTGCATCCATATATGCCACCCCACCGCCAGATCTGAGCAGCGAGGACACTGCTCTCTCCGACGTCTCCAACTCATCGACACTCAACACGAACAGGAACAACCACACCAGCggcgacaacagcaacaatccACATGAAGCCGCAGGAGCAACACCCACAGCCACGTCAGCCACAACCAGAGGagcaacaggagcaggaggagtgGACAGCTCTTCACCCGTCGCCCATTTGGTGCCGGCAAtggagctggaactggagcCGAAGCCAGCGGGAAGCGGAGCAAATGAGGCGGACCAATtggaggaggcggcggaggATGGGCGcaaggatgtggatgcggagGAGGAGGCTGGCGATGCCAACATGGCCACCATGGCGGCAGCCATGCAGCTGCAGATCCTGGAGGCCCTGAGTGATGCGGCCAAGAAGCGACGCAAGCAGCACAATCCCAGTCGCTTGGAAGCTCTCAATTTGAGTGGAGAACCCACTGGTGAAGTGGGTCAAAAGAATGCAGACTCCTCCACCTTGGACTTCGAGGAGAAGTTGTCGAAGATGTTCCTTCCCAAGTCGATTGAGCAGCTAAAGGAGACCTTCGAAATGCTGCAGCACCAGAAACAAGCAGGGCAACCGGAAACGGGAGAGGAAACGGAAGCGGAAGCCATGGCAGACATATCAGAATCCACCAAGCAGCGCGAGAACCCATACCACACTTACTGCAAGCAGTGCGGCGAGAGTTTCGAGACCGAGTTCAAGTTGAGCCTGCACATGCTGCAGGATCACGGCGAGGAAAGGTCCGGCGATCAGGATCCCGCTGACTTCCTGGCCTCCATCAAGGTGAAGCTGGAGCGCGCCGACATACCCAGTccgcagcaggagcagaatcTGCAGCACGACCTCACCAATGGTCATGGCAAGGACTTGGAGCGGGAGCAGGAGCACTGGTTCCAGGCCATGCAGGCGCAGCACCACCCACACGGGCCGCAAATGCCGCGCTTTCCCTTTCCACCAGAGGCAGCCTTGGGACCAGCTGGCTACCTGCCACTGCTCGGCATGTCCGGGTTTCCAGGCGTGGATGGCCTGAACCGCCCTCCACTGAGGATCTTCAATCCCGAGGCCTACTGCGAGCTGTGCAACAAGGAGTTCTGCAACAAGTACTTTCTCAAGACGCACAAGGCCAACAAGCACGGCATCTTCGATCCCGTGGGCGAATCCAGCACCAGCAACTCCTCCAGTCaccacaataacaacaacaatagcatCACCAGcagtaacaacaataacagtgGTCACCCCAATCCCAGCATGAGTTCCATGAGCCAAATGTTCCAGCTGCAACAGGCCCAAGTGCCGAAACAGGATCCCACACCAGCTGGCGGAGCATCGAATCCCGTGGCCTCAGTGCACTGCGACATCTGTTCCAAGCGTTTCACCAACATATTCGCCATGCGTCGCCACCGGGCCAAGCAGCATGAGGCACCACCAGTGGCCCAAGTTTCACCCAACTCCCAGGCACCCatgcaatcgcaatcgcacAGGGGAAGTCCCAACGAGCCACCACAGCCGACTATAAAGCAGGAAATGTCACAGGAAGCGGAGATCAAGCCGTATCAATTGCCCGAGGGTTTCCGCGAAGACTTCACCctggagcaggaggagctgaGCTTTGTGCCGCCGCCACGAAAGTTGCCCTCccatctgcagcagcaggcgaaGGACTCGAACTTCAATCCGGACAAGCTACGTCGCCTGGGCGTCCAGTTTCCCGACTTCTTCTGCGAGCTGTGCTACCGCGAGTATGCCAATCGGTACTTCCTACGCACTCACAAGTGGAAGCGCCACGGTCTGTTTGTGCCACCCGAAGACTTGGCTACACCAGGTGGCAAGGATGAAGCCCAGATGGCGAGTGCTTGGCCCTTTATGCCACTCATGATGCTGGccaaggcagcagcagccactatggatcagcaggagcaggaacgCGGGGATGCGGAAACGGAGTCAGAGCAGCCCAGTAAGAGGATCAAGTTGGAGCAGGGACAGACACCGCCGGAGGGATACGACGAGGATAAGCTGAATGGTTCGGTGGTGGGCCTGCAGAATCTGCAGAAGCTGCAGTCCATGTTGCAGCAACTGAACGACATCAATGGCAAACGCCCGCTACCCTGTCATCTGTGTggccaggagcaggagaaTCAGTATACCTTGAGGGCTCACTTGATGACCGAGCATGCTGGCCAGATGCAACTGCCCATGCCCATACCGATTCCACTGCCCGATCAGCAGGGCCCACATCCCATGGCCAGTCTGTACCATGCCCAGGGAAATCCGCATACTCCGCCGGCTCCGGGTGCCAGATCCCCGCCAGGTTGTGATCTGCGCTGCCAGCAGTGTGATCGTGACTTTGCCACACCCCAGGAATTCAAGCAACATATCGCCGAGGTGCACTTGGGCAGAAACGGAGGGCTGAGCGGAAGTCCGCTGCGCGATGGTTTCTTCACACCCGAACGCCCAGTGGCGCCGTCAGCGGGCGGACCCGGAACCCCCGCTCCCGCTGGAAATCGTCCACCTTATACCCTAACACCCACGAGCAGCTACTGTGAGATTTGCAACAAGGAGCTGTGCAACAAGTACTTCATGAAGACCCACATGCAGCGGATGCACGGCATCGAGATCGAGAATGGCGCCCAGATCGGTGGCGTGGTGTGCAACATATGCAACAAGGAGCTCTGCAGCAAGTACTTCCTGCTGCACAAGCACAACACCCATGGCATCATCGAGGAGGGATCCCCACTGCCACAACCAAGGGGTCAGAATGGAGTCAAACTGGACgcagccgccgcagcagcagcatcagcatcacaGCCATCGCAAGCGCAGCAGGATCAGGACCTCAATGTCTCACCACCCACAGTGGAGGGCAGTGGCGGCAGTTCATCCAACTCTGCCCACGAGGTGTGCCCACTCTGCTCTCGCCAATTCCGCAGCTTCAAGTGGCTGCGATCGCATCTGATGAACGAACACGGAACCGCCGGCGTGGAACGCCTCCGGGAAATGGAAACTACCCAATCCTCGACGCGCAGCAAGCCCAACAGTCCCACGCTCAAGATTCCCAACGGAAGTGGCAGCAACCCAGGAGCAGCGGGTGCCGGAGCCGGAAATACCGCTCCCAATCTCGCCCAGGCACTGCAAAATCTCAATGCCCAGCATCTCTTTGGccaaatgcaacagcagcagatgcCCAAGATGCCGCCGCTTCCATTGCCCGCAATGTTTGGCGAACAGGCGGCCAGGTTCAAGGAGTACCAGTGCTCACTGTGTCCCTTCACCACGCCCTACTACGCCTTCTTGTTCATCCACGAGCGATCGCATGCTCTGCTCAACAACGGCGGTGAGGGCATGGAGTTGCCCATGGAGACGCCGCCACCACAACCCACTAGAAGTTCGGGTAAATCACGCAGTAAGTCCAACAAATCCGTGGTGGCACCTCCGCCTAGCAAGTCCGAGGAAACAGAGCCCATCCTGGAGCCCACCAATCTCAGCACCTCAGCGCCAAAGGTCGCATCTCGTTCGCCCTCAACTGGGGCAGGATCTCCTCCCGCCTCCTCTCCAAAGGCAACCAGCTCAACTTCGCCCAAGATTCAACGCCGTCGATCCACCTCCAAGCCACCAACGACGCCAAACGCACTGGGCAGCACAACCGGCGGCCATCGGTCGGCGGCCACCTCGCCCTTTGAGGGCTGCGGGGATTTGGCCAACGGCACTGGCAAGCCGGCCAGCTATGCCCAGCCGGATGGGGCAGAGGAAGCATATCAGATGCAGGCCTTCCACCTGCAGCCCGCCGACGCGGACTCCGAGATGCAGTTCGCACCTGCCCTGGTGTACCTGCCCGTCCGCGTTCGCGCTTCGGAGTCGGCCACGCTCAGCTTCCGGCTAACACCTGCCTAA
Protein Sequence: MAASIYATPPPDLSSEDTALSDVSNSSTLNTNRNNHTSGDNSNNPHEAAGATPTATSATTRGATGAGGVDSSSPVAHLVPAMELELEPKPAGSGANEADQLEEAAEDGRKDVDAEEEAGDANMATMAAAMQLQILEALSDAAKKRRKQHNPSRLEALNLSGEPTGEVGQKNADSSTLDFEEKLSKMFLPKSIEQLKETFEMLQHQKQAGQPETGEETEAEAMADISESTKQRENPYHTYCKQCGESFETEFKLSLHMLQDHGEERSGDQDPADFLASIKVKLERADIPSPQQEQNLQHDLTNGHGKDLEREQEHWFQAMQAQHHPHGPQMPRFPFPPEAALGPAGYLPLLGMSGFPGVDGLNRPPLRIFNPEAYCELCNKEFCNKYFLKTHKANKHGIFDPVGESSTSNSSSHHNNNNNSITSSNNNNSGHPNPSMSSMSQMFQLQQAQVPKQDPTPAGGASNPVASVHCDICSKRFTNIFAMRRHRAKQHEAPPVAQVSPNSQAPMQSQSHRGSPNEPPQPTIKQEMSQEAEIKPYQLPEGFREDFTLEQEELSFVPPPRKLPSHLQQQAKDSNFNPDKLRRLGVQFPDFFCELCYREYANRYFLRTHKWKRHGLFVPPEDLATPGGKDEAQMASAWPFMPLMMLAKAAAATMDQQEQERGDAETESEQPSKRIKLEQGQTPPEGYDEDKLNGSVVGLQNLQKLQSMLQQLNDINGKRPLPCHLCGQEQENQYTLRAHLMTEHAGQMQLPMPIPIPLPDQQGPHPMASLYHAQGNPHTPPAPGARSPPGCDLRCQQCDRDFATPQEFKQHIAEVHLGRNGGLSGSPLRDGFFTPERPVAPSAGGPGTPAPAGNRPPYTLTPTSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVVCNICNKELCSKYFLLHKHNTHGIIEEGSPLPQPRGQNGVKLDAAAAAAASASQPSQAQQDQDLNVSPPTVEGSGGSSSNSAHEVCPLCSRQFRSFKWLRSHLMNEHGTAGVERLREMETTQSSTRSKPNSPTLKIPNGSGSNPGAAGAGAGNTAPNLAQALQNLNAQHLFGQMQQQQMPKMPPLPLPAMFGEQAARFKEYQCSLCPFTTPYYAFLFIHERSHALLNNGGEGMELPMETPPPQPTRSSGKSRSKSNKSVVAPPPSKSEETEPILEPTNLSTSAPKVASRSPSTGAGSPPASSPKATSSTSPKIQRRRSTSKPPTTPNALGSTTGGHRSAATSPFEGCGDLANGTGKPASYAQPDGAEEAYQMQAFHLQPADADSEMQFAPALVYLPVRVRASESATLSFRLTPA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512293;
90% Identity: iTF_00504958;
80% Identity: -