Basic Information

Insect: Drosophila santomea
Gene Symbol: -
Assembly: GCA_016746245.1
Location: NC:12725179-12727500[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 3e-06 0.00019 21.3 1.7 2 23 200 221 199 221 0.97

2 6 0.00011 0.007 16.4 1.8 1 23 227 250 227 251 0.96

3 6 0.00019 0.012 15.6 2.9 1 23 259 282 259 282 0.96

4 6 9.2e-08 5.9e-06 26.1 3.3 1 23 295 317 295 317 0.97

5 6 0.085 5.4 7.3 5.8 1 23 325 348 325 348 0.95

6 6 1.9e-05 0.0012 18.8 0.6 2 23 355 376 354 376 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	3e-06	0.00019	21.3	1.7	2	23	200	221	199	221	0.97
2	6	0.00011	0.007	16.4	1.8	1	23	227	250	227	251	0.96
3	6	0.00019	0.012	15.6	2.9	1	23	259	282	259	282	0.96
4	6	9.2e-08	5.9e-06	26.1	3.3	1	23	295	317	295	317	0.97
5	6	0.085	5.4	7.3	5.8	1	23	325	348	325	348	0.95
6	6	1.9e-05	0.0012	18.8	0.6	2	23	355	376	354	376	0.97

Sequence Information

Coding Sequence: ATGATGTTTGACTCGAAGCTGAGTTTGTGCGCGGGTCGCATGGTCGCCGattccaccaccaccaccacctgcGCCATGGAAGGACGCAATGTGGCCAAGACGCTGATATGCCGAGCCTGTCTGGTGCTGCTGGGTCCGCAGGATGCCAGCCACAATCTGGACAGCGAACAGGATCTGGCCAGCAAGTACTACGGCTGCACTGGCGGGGATCCGGGCAAGGATTTGCCACCCCAGTTGGTGCTGCAAAGCATCTGCGAGTGCTGCTATCAGATGGTGCAAAAGTTCCACGACTTTCAACGCATGTGCGAAGAGTCCTTGCGCAATTTTGAGAAGCTGCTGCACGACATCGACATGGAGTGCCTCAATCTGGTGGACCACATGCCCGACCTGGACACCCCCTCGGAGAGCAACGAATCCACTAATCCGGAAGCCCAAGTGGACGCACCCCGCCCCCTCGAATCGACGCAGGAGATTGAAGAAGTGTACGTGGTAGAGGACGAGTCGGCCCAACAGGATCTGGGCAAGGAGAAGCTACCCATAGCGGGCATTAGAAAGTGGCTGGGTGCAAGGAAGCGACGAGGAGTGCGACACACCCTCGAGTGCCGCATATGCCATCGTGGCTTCTACAAGTCGTCGCTGCTGGAGGCCCACATGCGGAAGCATGAGGGTCTGCGGCCGTATACCTGCGTCCATTGTGCCAAGAGTTATGCCAGGGCCAATCTGCTGGAGTCGCACCTGCGGGAGATGCATCACAATAGCGCCGCGAGGATAATCCATGCCTGCCCGCACTGCAATAAGGTGTACACAGCGGACCGCAGTCTCAAATATCACATGAAAAGGGCGCACGAAAGCAATCATAGGCCAGAATCACCCGATGCACTGCACATTTGTGAGGAGTGCGGCAAGTCCTTTGTGCGAAGGGCGCATTTAACGCGCCACAAAAGGGTCCATGGAAGCATAGAGGGTCGGAGATACTGCTGCGAGTGCTGTGATCAGAGGTTCTACACCAAGGAGAACATGGTGGATCATCTGCAGCGGAAGCACGGAAGCAAGAATCTGCTCAGATGTAGAAAATGCGGACGCATTTTTAGGAGCAGTGTGGAGCTCAGCGCTCATGCGAAGAAACACGAGGCGATGTAG
Protein Sequence: MMFDSKLSLCAGRMVADSTTTTTCAMEGRNVAKTLICRACLVLLGPQDASHNLDSEQDLASKYYGCTGGDPGKDLPPQLVLQSICECCYQMVQKFHDFQRMCEESLRNFEKLLHDIDMECLNLVDHMPDLDTPSESNESTNPEAQVDAPRPLESTQEIEEVYVVEDESAQQDLGKEKLPIAGIRKWLGARKRRGVRHTLECRICHRGFYKSSLLEAHMRKHEGLRPYTCVHCAKSYARANLLESHLREMHHNSAARIIHACPHCNKVYTADRSLKYHMKRAHESNHRPESPDALHICEECGKSFVRRAHLTRHKRVHGSIEGRRYCCECCDQRFYTKENMVDHLQRKHGSKNLLRCRKCGRIFRSSVELSAHAKKHEAM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00596864;
90% Identity: iTF_00607941;
80% Identity: -