Basic Information

Insect: Drosophila santomea
Gene Symbol: -
Assembly: GCA_016746245.1
Location: NC:3777809-3783831[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 8.8e-08 5.6e-06 26.1 1.8 2 23 133 154 133 154 0.97

2 9 2.2e-07 1.4e-05 24.9 1.6 1 23 160 182 160 182 0.98

3 9 1e-07 6.6e-06 25.9 1.1 1 23 188 210 188 210 0.98

4 9 6.2e-07 4e-05 23.5 0.7 1 23 216 240 216 241 0.95

5 9 3.7e-05 0.0024 17.9 3.1 1 23 246 268 246 268 0.97

6 9 0.00034 0.022 14.9 3.3 1 23 274 297 274 297 0.98

7 9 0.00025 0.016 15.3 1.5 1 23 303 325 303 325 0.99

8 9 3.5e-06 0.00022 21.1 0.8 1 23 330 352 330 352 0.98

9 9 0.0036 0.23 11.6 0.3 2 23 359 383 358 383 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	8.8e-08	5.6e-06	26.1	1.8	2	23	133	154	133	154	0.97
2	9	2.2e-07	1.4e-05	24.9	1.6	1	23	160	182	160	182	0.98
3	9	1e-07	6.6e-06	25.9	1.1	1	23	188	210	188	210	0.98
4	9	6.2e-07	4e-05	23.5	0.7	1	23	216	240	216	241	0.95
5	9	3.7e-05	0.0024	17.9	3.1	1	23	246	268	246	268	0.97
6	9	0.00034	0.022	14.9	3.3	1	23	274	297	274	297	0.98
7	9	0.00025	0.016	15.3	1.5	1	23	303	325	303	325	0.99
8	9	3.5e-06	0.00022	21.1	0.8	1	23	330	352	330	352	0.98
9	9	0.0036	0.23	11.6	0.3	2	23	359	383	358	383	0.95

Sequence Information

Coding Sequence: ATGGACACCATCTGTAGGTTGTGCTTCCAAACGGCAACGTTGTTCCAGGTGCCCGGCTATAGCATACCCACGTGCGTCCGCTGCTCGGAGCAGTTGACAAATAATTCCAACTTCCATCAGTCGGCGGCGGCCGCTGCCgccgtcgctgcctctgcctcgGCCGCAGTCGCCGCCTCCGCAGCAGCGGCGGCCACCTCCTCGTCGACGGCCTCCTCGAGCGACAGCGACGCCAtcgcgcagcagcagcaccagaacccgcagcagcagcatcagaactcgcaacagcaacaacagcagcagcagcagcagcagcaaatgcaatCATCCAGTTCTTCCGAGAACCTACAGTCGCAGGACGACTCCGAAGACGTGGATCTGATATTCAACGAGGAGGGCTCCTGCCCGCTATGCAACAAAACGTTCTCGCGCAAATCCTCGCTCATGACGCACATACGAAATCACTCGGCGGAGCGTAAGTTTGTGTGCACCTACTGCCACAAAGGCTTCACGCAGGCGGCCAACTTGCGGAACCACGAACGCATCCACACAAACGATCGGCCATACCAGTGCGTGGACTGTGGCAAGACCTTCACGCAGATCACCAATCTGAACAATCACCGCCGGCTCCACACCGGAGAACGGCCCTTCGTCTGCAATGAACCGGAGTGCGGTCGCAGTTTCGCCCAGGTGACGAACCTGAACAACCACATGAAGTCGCACCACAAGGTGCAGCAGTACTGCTGCAACGTGTGCAACAAGAAGTTCACGCAGGTGACCTCGCTGAACCAGCACCTGCAGGCGCACGCCGGGGTCACCGGCTACTACTGTCCACGGTGTCCGGAGAAGAACTTCAAGCTGCAGTCGCAGCTGCACACGCACATGAAGACCCACGGCCTGGCCTTTCCGTACGAGTGCGACAAGTGTGACGAGAAGTTCCTGCAGCAGGCCCATCTCGATCAGCACCTCAAGATGCACGACGagttcaagttcaagtgcGACATCTGCCCGAGCAGCTTCAACCAGGAGTCGCTGCTGAAGAAGCACGTGCAGCGCCATGTCGAGGGTCGCTACCTCTCCTGTCCGGTGGCCAATTGTGCCGAGTCCTTTGCGGTGCGCCAGCACCTCTCCAAGCACCTGCTCACCAACCACGCCCACCACGAACTGCCGCCTCCGAAGCGCTCCAAGAAGGCGGGCACGCAACAGCCGCTGGCAATGATCGGCCAGCCGTTGTCCCTGCAGCACACGACAGGGCAACGTGGACGTCCGCcgaagaacaagaacaaggcGACAACGCTGGCCGCCACGGCCATCAAGATCGAGATCAACGAATCGCTCCACAGCCAGCATATCAGCAATGTCAGTGGCCTGTCCATCCAGCAGCAGATCAACCAGCacatgcagcagcaggcggcacagcagcaggcgcagcagcaggcacaacaacagcagcagcagcaggcggcggcggcgcaacagcaacaggcgcagcagcagcaactgctgcATTTGCCGATGGGCCAGACGGTCAAGGCGCGTTTCATACCCACTAAGTAG
Protein Sequence: MDTICRLCFQTATLFQVPGYSIPTCVRCSEQLTNNSNFHQSAAAAAAVAASASAAVAASAAAAATSSSTASSSDSDAIAQQQHQNPQQQHQNSQQQQQQQQQQQQMQSSSSSENLQSQDDSEDVDLIFNEEGSCPLCNKTFSRKSSLMTHIRNHSAERKFVCTYCHKGFTQAANLRNHERIHTNDRPYQCVDCGKTFTQITNLNNHRRLHTGERPFVCNEPECGRSFAQVTNLNNHMKSHHKVQQYCCNVCNKKFTQVTSLNQHLQAHAGVTGYYCPRCPEKNFKLQSQLHTHMKTHGLAFPYECDKCDEKFLQQAHLDQHLKMHDEFKFKCDICPSSFNQESLLKKHVQRHVEGRYLSCPVANCAESFAVRQHLSKHLLTNHAHHELPPPKRSKKAGTQQPLAMIGQPLSLQHTTGQRGRPPKNKNKATTLAATAIKIEINESLHSQHISNVSGLSIQQQINQHMQQQAAQQQAQQQAQQQQQQQAAAAQQQQAQQQQLLHLPMGQTVKARFIPTK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00533229;
90% Identity: iTF_00505550;
80% Identity: -