Basic Information

Insect: Drosophila santomea
Gene Symbol: hang
Assembly: GCA_016746245.1
Location: NC:10340713-10356307[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.24 15 5.9 1.0 3 23 307 328 306 328 0.93

2 19 0.31 20 5.6 3.2 3 22 436 455 434 455 0.89

3 19 0.00052 0.033 14.3 3.3 1 22 568 589 568 591 0.90

4 19 0.06 3.8 7.8 0.1 2 21 603 622 602 623 0.93

5 19 0.00061 0.038 14.1 0.2 2 23 760 782 759 782 0.95

6 19 0.0017 0.11 12.6 0.1 1 23 790 813 790 813 0.96

7 19 1.4e-05 0.0009 19.2 0.1 2 23 898 919 897 919 0.97

8 19 0.00025 0.016 15.3 2.9 2 23 1002 1024 1001 1024 0.97

9 19 0.02 1.2 9.3 0.2 2 23 1033 1055 1032 1055 0.95

10 19 0.00032 0.02 15.0 0.2 1 23 1068 1091 1068 1091 0.97

11 19 0.00011 0.0069 16.4 1.1 1 23 1140 1162 1140 1162 0.99

12 19 0.0017 0.11 12.7 0.9 1 23 1170 1193 1170 1193 0.96

13 19 7.3 4.6e+02 1.2 0.2 2 13 1201 1212 1201 1214 0.85

14 19 2.8e-05 0.0018 18.3 1.4 3 23 1309 1329 1308 1329 0.98

15 19 0.0044 0.28 11.4 0.1 1 23 1364 1386 1364 1386 0.97

16 19 0.00052 0.033 14.3 0.6 2 23 1465 1487 1464 1487 0.93

17 19 0.73 46 4.4 0.1 2 20 1507 1525 1506 1527 0.91

18 19 0.0057 0.36 11.0 0.4 3 23 1542 1562 1542 1562 0.98

19 19 8.9e-05 0.0056 16.7 2.1 1 23 1857 1879 1857 1879 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.24	15	5.9	1.0	3	23	307	328	306	328	0.93
2	19	0.31	20	5.6	3.2	3	22	436	455	434	455	0.89
3	19	0.00052	0.033	14.3	3.3	1	22	568	589	568	591	0.90
4	19	0.06	3.8	7.8	0.1	2	21	603	622	602	623	0.93
5	19	0.00061	0.038	14.1	0.2	2	23	760	782	759	782	0.95
6	19	0.0017	0.11	12.6	0.1	1	23	790	813	790	813	0.96
7	19	1.4e-05	0.0009	19.2	0.1	2	23	898	919	897	919	0.97
8	19	0.00025	0.016	15.3	2.9	2	23	1002	1024	1001	1024	0.97
9	19	0.02	1.2	9.3	0.2	2	23	1033	1055	1032	1055	0.95
10	19	0.00032	0.02	15.0	0.2	1	23	1068	1091	1068	1091	0.97
11	19	0.00011	0.0069	16.4	1.1	1	23	1140	1162	1140	1162	0.99
12	19	0.0017	0.11	12.7	0.9	1	23	1170	1193	1170	1193	0.96
13	19	7.3	4.6e+02	1.2	0.2	2	13	1201	1212	1201	1214	0.85
14	19	2.8e-05	0.0018	18.3	1.4	3	23	1309	1329	1308	1329	0.98
15	19	0.0044	0.28	11.4	0.1	1	23	1364	1386	1364	1386	0.97
16	19	0.00052	0.033	14.3	0.6	2	23	1465	1487	1464	1487	0.93
17	19	0.73	46	4.4	0.1	2	20	1507	1525	1506	1527	0.91
18	19	0.0057	0.36	11.0	0.4	3	23	1542	1562	1542	1562	0.98
19	19	8.9e-05	0.0056	16.7	2.1	1	23	1857	1879	1857	1879	0.98

Sequence Information

Coding Sequence: ATGTGCGACGCTGcggcggcaacagcaacaacaacatcatcagcagcagcagcagcagtagtcgcaacaacaacatcaacggTAACAGTGGAGGCCATAGCGACACAGCCTGGAACGACGACGGTAGCCACTGCGTCAGCGGGAACCACATCCCCTGAAGCAGCCAttccaacaacaacatcggCCAGAAACAGCGAATGGTCGGCGCGACAAAACTGCTGTCGCCTGTGCATCGCCCCACAAACCGAATGCATCTCGATCATCAATAGCTATGCGGCGGACAAGGAGCCACTGTCCACCAAGATCCACAACTGCGTCGGCATCAAGGTTACACCGCAGGATCGGCTGTCGCAGCAAATTTGCCACGCCTGCATCAGTTACCTGAACTCATGGCAGAGCTTCAAGAACCGGTGCTTCAGCTCGCAGGCGAAGCAGCGCCAGTGGCTGGATGCCAACAAGAGCAAGCTCCTCAACTACCTGGACCTGAACAGCGCCGAGAATGGGGGAGGAGGCTCCTTCGATCAGCAGCTgcatcaacaacagcaatcGGAGAATGAGCTCGAAGCGGAGAAGGCGACGCCAACGGCCGCATCGACCGCGGCCAACATTTTGGACGGCATACACTCGCTGAAGAAACGCAAATCCCTAACAGTCTATCCACTGCCTGCGATTCCAATCAAAGATGAGCCAATTGACACGGATGACGACTACCAGATGAAGTCCATAGACGAATCCGATGACATGGTCGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTCCCGCTGACGGCCTCGGACTACGACTACACTGCACAGCATGGCGTGAATGCCTCGTCGGTGGCTGCCGCGCTGCCGCCGAATGCGGTGGCCAATGTGGCAGCCGCCGGGGACTCCAAGGTGGCCAGCTGCAGGGCATGTAGCTTGCAGTTCTCCACCCGGGCCAACGCCCGTCGCCACGAAAGGAATCTGCACCCAAACCTGTTCCAGTTGTCCACAGACTCTCCCCACAACACACCCATCACGAAGCCAACGCCCGCCCTGGCTGCCGCCTTGGAAATCCAAcgggcagcggcagcggcggccacCGCGGAGGCAAATCGGGCAGCGGGCGCTGCTGGCGGGAATATCTCCACGCAAAAGTACCGCCAGGTGGTGATGAACGCGTTTATTAAGTGCGAGGGCGGCGGCTACGACTACGATAATCCCGAACAGTACCGACCACTGCTCACCCGCGACAAAGTGGAGTTCATTGAGCAGAACGACGAGTTCCTTGAGCAATACCAGACGATGACCTGCCGATGTTGCAACAAGTACTTCAGCACGTACAAGAACTTCATGGCGCACGTGCGCAAGAAGTATCCGCAGCTGCCGCGCAACCTTtgcttcaattgcctcaagaTGAACGACTCCAAAGCGCTGTTCATCTCGCATCTGAAGAAGCGAAATTGCATAAATCTCTTTAGAGTGTTGAATGCGCTGCGTGGTAAAACAACGACAGTGATGGTGCCCACTGCCGAGGATATGACAGACGATGGAGCAACAGGAGTTGTTGCGATTGCCGATGCCGGAGCTGGAGCGGTGGCCATGAATAGTCCCACAGTGACAGCGAGCGGTGAAGTTGTTACACCCGGCGGTGGCTCCGAGCGCCCAGAGAAACTGCGCGCCAAGGAACTTCTGGTCAACAAGCTGTACGAGTGCAAGCTCTGTCCCAAGGGATTCCGCACCAAGCACGAGTTCCGAACGCATGTTTACGACAAGCACGCGGATGTCCAGCGCAAGGATAACAACTCGATACAGTGCAGCTTCTGTGGGCTGGATTTTGCTGATCCCGTGGACAGACGGCGGCACTACAACAACATGGACTGCATTGTCCGGCTGCGCTGCATGACGTGCGATGCCAAGCTGGAAACGCACCAGCGATTCCTCGATCACGTCTATCAGGATCATTTGGGCGGCGTGGGTGGTGGGGCGGTCAGCGACAATGCCTCCACCACTGGCAGCGGCATGGCCAGAAGCAACAGCATGGAACATTCGCCGGGCAAGAGGAGCCTGCTCGGCGCCTTAGGTATTGGTGTTGGTTCCTCGGCGGAGGAGTCGCGAAGCAGCAGTGCGGCTCCGCCACTGACCTCCACACCAAAGCCGGCGGGGGGTACTCAGGTGGGTGGCGGTGGATCCACCAGCGCCTCTGCCGCCGCAGCCGCTCAGAACTCAGCGAATCGGGATGCATCCGCACCCAAATCCCAGTACTTCTCCCGTATGCCGCAGGTATGCCCCATTTGCGGCCAGCAgtacaacaactacaacaatgTGCTGCGCCACATGGAATCAAAGCATCCGAACAAACTGCCAGAGACATACAAGTGCGTGCGATGCGGACTGGGTTATCCACGGATCTCCTACCTACGCGAGCATATGATCAATGTGCACGGCGTGGACAAGAACCGACACTCTGGCGGCTTCGAATACATTGTGAACGCGGATGCCGTGAAGTTGGCGGACGGAAGCACGCCGAACGTCTACACGGGTCGCTACGACTACGTGATGAAGGACCTGATGTCGATAACAAATGGTGGGACACTCGATGATGAAGAGGAGGAGCCTGGCAGCGTGGCCAAAAAGATGCGCCTGGatgacagcagcaacaacagcagcctggtgggcgtggctagCCAGCAGAAGGAGTGCCCCATCTGCAATGCGGTGTTCAGCAACAACATTGGCCTGTCCAATCATATGCGTTCCCACTATACGGCATCGAATGCAGTCAATGCAGCTTTGGCGGCTGCCAATCGGATGACACCCAAATCGCTAACGATTACcgcaacaccagcagcggaTTCGGATCTGGGATTTGGAGGAACAATATCAGAGTCGGCTCCAGCAACACCTGCTGCCAATGTGCCACCGGCAATGGCCAACCAAACGCCCCAGGAGCAGGCAGTTTTTCGACGTAGCCTTGATCAGGCAGCCGATCGCCGCTTTCGGCGAATGCGGTGCCGCATCTGCCAGCGTCGTTTCAGTTCGAAGAAGTCCTATCGCTACCACATGCTCACCGATCATCAGGTGCAGAATGTGCAGTTCATCAAATGCAAGCTGTGCAACGCTGAGTTTGCCTACGAGAAGGGCCTGAAGGTGCATCTGTTCAAGGTGCACGGAAGGGCCATCAAGGATGAAATGATTATCAAGCAGTTCGAATGTGAGGTTTGCTCGATCGTCTATAGTTCAGAGACGGAGCTACAGCAGCACAAACGCAGCGTTCACAAGCTTACTTCCACATCGGCGTCCACGTCCTCTAAGATTGACGATGACTCTCTTATGGACGAGGTCAAGCCTACAGCAGCGGATCTAGCTGATCTCTCCACCCTCGCGGCCGGTGCATCCACTGCATCTGCTCCACTGTACTGGTATCAGTGCAAGTACTGTCCATCAAACTTTAACACCAACAAGAAGCTGGCCATCCACATCAACTCGCACGACGAGTTTGACTCGAACGATTATTCCTGCAAAGATTGCGGAAACGTCTACAGCGGACGCAAGAGTCTATGGGTTCATCGCTATAAGAAGCATCCGCAAGTGCCCAACCCAGCTGAGTGCTCGCTGTGCCGCAAGGTCTTCTTCGACCGCCAGATGCATGACAACCACACGCCCACCTGCAACCGCAAGCCGATCACCTCGACAGGTgcccaccagcagcaggatgcacagctgcagcaacagcaggcgcTCCAGCCGGCCAGAAGAACAGTTTTCCGGCATAAGAccggcgatgacgatgacgaggatgatgacgatgagCACCAGCAACTGGAGGAGAGGGGAAACAGCGATGGCAATGGCACAACTGCCGGAGTGGCGTCGGGCAGTACTGTAACTGCGGGCACGTCACTAAAGATTCGCATTCCGGAGGTGGCGTGCACCATTTGCGGTGCTCGTTTCACCGACCAGGAGCACTTTAGCAAGCACATCCAGAAGCACGAGCAAGAGCTGTACGTGGACAATCCACTGGCGGCGATGTTCGACGATGGGCCGGCGGATGCCGGTCAGTTCCAGGTGGAACGACAAAATGAGAACGGGGAATACGCGTGCGATTTGTGCGCCAAGACGTTCCCCCAGGTGATCGCACTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCCCATCGACGGCGAAGCGACACAGTTGACCAACAACAATCacacaaccaacaacaacaacaactcgATGCTGCACCTCCGCGAGCTGCATGCGGTGGGCCTGATGcccaaccagcagcagcagagcctCAACAACTcgtgcaacagcagcatgaaccacaacaacagcagcagcaaccgcagcaaATCAATGAAGCGGAAACGTGAGCTGAAATGCGAATACTGCGCCTCCACCTTCATCAGCAATAACAATCTGCGTCGCCACATGTACGAGCTACACAAACACGAGGTAAGCAATCTGCCCGAGCCGCCGGTGATTGTGGTGGACGATCACCTCACCTGCCGTCGCTGTCAGTTAACGTTCGACACAAAGGAGCTGTGGATCGAGCACAAGCTGGCCGATGCTAAGGTGGTGCGACCCTTCTGCCCCTTCCAGTGGGGCTGCGATCTGTGCGGCGAGTATCTGTCGCGCAAGGAGAAGCTGATGAACCACATTAATAACCATTTAAAGGAGGAGGTCATAGTGCCAGTGGCCACTAAGGCGGCCATGGAGAGAACAGCGGCCATggaagcagcggcagcagatGCAAACACATCGGCGCCACTATCAACATTAGGCGAAGGAGCAGAATCTGAAGATAATTTTGTAGAGAAAGGTGAGGCTGCAGGAGCAACAACATCAGAAAAGATGTCGAATCCCGATGAGGAAGATAGCGATGATTTGGACGAGGATAGCTCCGGCGATGAGGATGAGAGTTCAGGCACCGgagatgatgacgatgacgacacGGACGATGAGGATGGCGAGGGTGaagacgaggacgaggagggaGATGGTGGCGAAGGCGAGGACGAAGAGGGTGTGCAGCCTCCCGCTCAACTTTTGACACAGAAGCAACACAAAGCGAGTCTTAACCAGGACGACGATGATCTTGTCGAGGAGGTCATCAGCTCCGAAgacgatgaggatgatgatggAGAAGTGGAAagcgacgatgacgacgatgatgatgacgatgaggaggaCGATGTGGAGGAGCCGGAGCCAGTGGCATTGCCGGTGCGACCGCTAATGAATGGCAAATCAAAGATGCCGCCGCTGATAGTGGCCAGTTCggaggatgaggacgatgGTGTGATGCCCATAGAGGACATCATCGAAGAGGAGTTCGATGAGGATGCCGATCCAGATCCCGATCCGGAGGATGCCATTGAGGAGGTAGACGACGATGATTTAGATGAGGGGGATGTGGAGGACGAGCCGAATGTGGTGTCGACGGCCTCCTTTTCGGAGAGCGAGTCCACCACAACGACCACGTCcaattcgcattcgcattcaaCGGGTGAGCGGCGTAAGAAGGCCGACGATCAGTTGAATGATCCCGGCTTTACCTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCTTCTCCAGAGCCACATCAAAAGTCATATCCTCAATGGGCCAAAGCTCTCaacagcgccagcagcagcggcaacaacagcaagcaGCACGGCAACCGCATTAGTAACGGCAGCCAAGACGAAGCCTGACTCCAAGTCAGCGGTGCTggccaacaataacaatagcAAGACAAGCAGTAAGACTGTTGCTGCCacggcggcagctgcagcaactgcgACAAATTGA
Protein Sequence: MCDAAAATATTTSSAAAAAVVATTTSTVTVEAIATQPGTTTVATASAGTTSPEAAIPTTTSARNSEWSARQNCCRLCIAPQTECISIINSYAADKEPLSTKIHNCVGIKVTPQDRLSQQICHACISYLNSWQSFKNRCFSSQAKQRQWLDANKSKLLNYLDLNSAENGGGGSFDQQLHQQQQSENELEAEKATPTAASTAANILDGIHSLKKRKSLTVYPLPAIPIKDEPIDTDDDYQMKSIDESDDMVDPTMFLERSEHEGDVPLTASDYDYTAQHGVNASSVAAALPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPHNTPITKPTPALAAALEIQRAAAAAATAEANRAAGAAGGNISTQKYRQVVMNAFIKCEGGGYDYDNPEQYRPLLTRDKVEFIEQNDEFLEQYQTMTCRCCNKYFSTYKNFMAHVRKKYPQLPRNLCFNCLKMNDSKALFISHLKKRNCINLFRVLNALRGKTTTVMVPTAEDMTDDGATGVVAIADAGAGAVAMNSPTVTASGEVVTPGGGSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVGGGAVSDNASTTGSGMARSNSMEHSPGKRSLLGALGIGVGSSAEESRSSSAAPPLTSTPKPAGGTQVGGGGSTSASAAAAAQNSANRDASAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDEEEEPGSVAKKMRLDDSSNNSSLVGVASQQKECPICNAVFSNNIGLSNHMRSHYTASNAVNAALAAANRMTPKSLTITATPAADSDLGFGGTISESAPATPAANVPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECEVCSIVYSSETELQQHKRSVHKLTSTSASTSSKIDDDSLMDEVKPTAADLADLSTLAAGASTASAPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPNPAECSLCRKVFFDRQMHDNHTPTCNRKPITSTGAHQQQDAQLQQQQALQPARRTVFRHKTGDDDDEDDDDEHQQLEERGNSDGNGTTAGVASGSTVTAGTSLKIRIPEVACTICGARFTDQEHFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIDGEATQLTNNNHTTNNNNNSMLHLRELHAVGLMPNQQQQSLNNSCNSSMNHNNSSSNRSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIVVDDHLTCRRCQLTFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLMNHINNHLKEEVIVPVATKAAMERTAAMEAAAADANTSAPLSTLGEGAESEDNFVEKGEAAGATTSEKMSNPDEEDSDDLDEDSSGDEDESSGTGDDDDDDTDDEDGEGEDEDEEGDGGEGEDEEGVQPPAQLLTQKQHKASLNQDDDDLVEEVISSEDDEDDDGEVESDDDDDDDDDEEDDVEEPEPVALPVRPLMNGKSKMPPLIVASSEDEDDGVMPIEDIIEEEFDEDADPDPDPEDAIEEVDDDDLDEGDVEDEPNVVSTASFSESESTTTTTSNSHSHSTGERRKKADDQLNDPGFTCDLCQLCFDSQELLQSHIKSHILNGPKLSTAPAAAATTASSTATALVTAAKTKPDSKSAVLANNNNSKTSSKTVAATAAAAATATN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00578694;
90% Identity: iTF_00619286;
80% Identity: -