Dsan001867.1
Basic Information
- Insect
- Drosophila santomea
- Gene Symbol
- -
- Assembly
- GCA_016746245.1
- Location
- NC:19640935-19649669[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 9.2 5.9e+02 0.9 0.7 2 23 151 173 150 173 0.90 2 13 0.0017 0.11 12.6 5.0 1 23 192 215 192 215 0.97 3 13 5.5e-06 0.00035 20.5 4.9 2 23 222 244 221 244 0.96 4 13 0.0087 0.55 10.4 9.0 2 23 474 495 474 495 0.97 5 13 1.6e-06 9.9e-05 22.2 2.9 1 23 501 524 501 524 0.95 6 13 0.00053 0.034 14.2 0.8 1 23 529 552 529 552 0.93 7 13 5.1e-05 0.0033 17.4 5.5 1 23 570 592 570 592 0.96 8 13 1.9e-05 0.0012 18.8 0.7 1 23 597 619 597 619 0.98 9 13 2.7e-05 0.0017 18.3 1.7 1 23 625 647 625 647 0.95 10 13 9.1e-05 0.0058 16.7 0.8 1 23 653 675 653 675 0.98 11 13 2.8e-07 1.8e-05 24.6 2.7 3 23 683 703 682 703 0.99 12 13 2e-08 1.3e-06 28.1 1.1 1 23 709 731 709 731 0.99 13 13 0.31 20 5.5 3.4 1 19 736 754 736 759 0.89
Sequence Information
- Coding Sequence
- ATGGCAACGCCACAGCCGCACTTGCATCCGCAGCTGGAGCCGGGTTCGTGCCAGGAGACGGAAACTGAGCCGGCGGGCAGCAAGTTGGTGTCCCAGTTGGAGCCCCTGACCACAATAGACACCGTGGACGCGGAGCGTGTCTGCCGCGTTTGCCTAAAGGACGGATCGCTGGAGGGGGAGCTGCACTTCATCTTCAACGAAGCACCCGTCGAGCAGGGCGCCAACCTGGCCCGTATTCTGGACGAGTGCACCCTGCACCAGTGCGAGCGGTACGACGGGATGCCCTCACATATGTGCGGATCCTGCGTGGAAGCGGCCCGCAATGCCTACCGCTTTAAGCGGCACGCGGAGCGCTCCTACTGCTCACTGGTGGCCATGCTGGGCCGTTCGCCCCAGCTTAAGGCACGAGGAGCCGAGGCGGCCAGTCAGACGGATCAGGTGGCCTTGCTGCCATGCGAAATGTGCCACGACCAGTTCCTCAACAGCCTGGAGCTCCGGCTGCACCGCAACCAGGTTCACAGAACGACCAAGGAGGGCACGGCAACTGGAACAGATGGGCTTCCATCCGAAGAATTTAAGTGCAAGTTTTGTCCGCAGCATTTCCCGCATCTCCGACAGCTGCGCAGCCATTTGGCGCGCAGCCACGAGCAAACCGCACGACTTCAGTGCGCCCATTGTCAGCGCACTTTTAGCCGCCGGGATCATTTGCTGCGCCACATACGCAATCAGCACCGGGATGTGGAGGAGGATCTTCTACGTACCTGGACGCCGGCGGACGAGAACACCATGAACAGCGATGGCGGTGATGAGCTGGTTTCTGCCGAGGTGCTGTTAAACGAGGAGGAAGACGATGATGAAGGCGTCGCAGAAACCTTCCAGTGCAATACGAATCCCATTTCCAGCAACGACGAGGATGACGAAGATGCCAATGGGGTCAATCAAACGCTGTGGCTGCACATCAAGCCGGAGCCCTGCCTGGAGGCGGAAGAAGTCGACCTGGCCATGCAGCTGAAGCTCGAGAAGAAGCGTCGGCGGCGGGAAAAGGCGGAAGCTCAAGCTGAAACTTCCATCGATCGGACTGTGAAAAACGAACCCATTGCCATCGGCGACTCTCAGTTCAGCATTAAAGAAGAGAGTCACCTTGTGGGCAGCGAGGACGAGGCGTTAATGGGAGTGGAAGACTTCATGAAGCTCCATGTCAGCGGAGAGCTGCCTCTCAGCGATGAAGAGCGGTTTGATGATTTTGCAGACGATAACAGTGAccttgatgatgatgacgacgacgacgaggatggTGGGGAAGATGATGACGGCGAATTTCGGTTTAAACAGGAGCCGCTGGACGGCGAGAAGCCGCTGAAGAAGTCGAAGTCAGGCAGGCGCCGGCGACGCAACAAGGGCGAACCCAATCCCGAGAATCGCTGCGAGGTGTGCCAGCGCACCTTCTCGCGCCACTGCCACCTGCTGCGCCACAAGTTGTCGCATCTGGAGAAGAAGCCCCACAACTGCCCGCACTGCCCCAAGGCGTTTGCGCGCAGCGACCACCTGAAGGCGCATGTGCAAAGCCTGCACAGCAACAAGGAGCACAAGTGTTCGCTCTGTGAGGCTGCCTTCTCGCGTCTGGACGCCTTGGAGCGTCATAAGGTCAGCAAGCACAACGGTGAGGGCCTGGAGCCGGGCAGCGAGCTGAAGCTGCAGCTGGCGGAGCACACTTGTGAATACTGCTCGAAGCGCTTTTCGAGTAAGACCTACCTGCGTAAGCACACGCTGCTGCACACCGACTTCCTCTACGCCTGCAAGACCTGCGATGAGACATTCCGCGAGCGAGCGCAGCTTAGGGAGCACGAAAAGACCCACACCGGACAGCGTAACTTCCTCTGCTGCATTTGCGGCGACAGCTTTGCCCGCAACGACTACCTCCGCGTGCACATGCGGCGCCACAACGGTGAAAAGCCTTACAAGTGCCGCTTCTGTGTAAAAGCCTTTCCCCGCGCCACTGATCTCAAGGTCCATGAGCGTTACCACACGGGCACCAAGCCGAATCTGTGCAATACCTGCGGCAAGAGCTTCCACCGCGCGTACAATCTAACGATTCACATGCGCACGCACACCGGCGAGCGGCCGTACAAGTGCGACCAGTGTCCCAAGAGCTTCACGCAAAGCAACGACCTAAAGGCGCACATCCGGCGGCATACGGGCGAGCGGTACAAATGTCCGCACTGCGATGCCTACTTCCTGCAGCTGTACAATATGCGTAATCACTGTTTGAGCGCCCACAACAAGCACATCGAGACGAAGACGGGACGTCTGCAGCGGACGGGTCTGCTGGAAGATGGTGGTCAATCGCATCTGACCACCGTCGTTATGCCGCCGGCACGGTATCCAAATGAACTGGATCCCCAGCTAGCGGCGACTGCAGCTGCCGGGGCTGAGAGCTCATCGTCGACCACCGTCATTCACTCGCCGGGTACATACAACGCCACATCTGCTGGACTGTCCACGGGAGCAGCGGCCGCAGCTCCAGCTAATACGCTCGATGGAGCAAGCTTCGCACCCGCGGCAGTGAATACGTCTGCACCGTTTGGTGCCTTCAACTTTCCACCGGTCGTAATGGCGCATCTCATGTACAACCACGGAGGAAGCAGCCAGCATAGCCAGAGCGGAAGCGAGACGGGCAAATAG
- Protein Sequence
- MATPQPHLHPQLEPGSCQETETEPAGSKLVSQLEPLTTIDTVDAERVCRVCLKDGSLEGELHFIFNEAPVEQGANLARILDECTLHQCERYDGMPSHMCGSCVEAARNAYRFKRHAERSYCSLVAMLGRSPQLKARGAEAASQTDQVALLPCEMCHDQFLNSLELRLHRNQVHRTTKEGTATGTDGLPSEEFKCKFCPQHFPHLRQLRSHLARSHEQTARLQCAHCQRTFSRRDHLLRHIRNQHRDVEEDLLRTWTPADENTMNSDGGDELVSAEVLLNEEEDDDEGVAETFQCNTNPISSNDEDDEDANGVNQTLWLHIKPEPCLEAEEVDLAMQLKLEKKRRRREKAEAQAETSIDRTVKNEPIAIGDSQFSIKEESHLVGSEDEALMGVEDFMKLHVSGELPLSDEERFDDFADDNSDLDDDDDDDEDGGEDDDGEFRFKQEPLDGEKPLKKSKSGRRRRRNKGEPNPENRCEVCQRTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQSLHSNKEHKCSLCEAAFSRLDALERHKVSKHNGEGLEPGSELKLQLAEHTCEYCSKRFSSKTYLRKHTLLHTDFLYACKTCDETFRERAQLREHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRFCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGERYKCPHCDAYFLQLYNMRNHCLSAHNKHIETKTGRLQRTGLLEDGGQSHLTTVVMPPARYPNELDPQLAATAAAGAESSSSTTVIHSPGTYNATSAGLSTGAAAAAPANTLDGASFAPAAVNTSAPFGAFNFPPVVMAHLMYNHGGSSQHSQSGSETGK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00504826;
- 90% Identity
- iTF_00596789;
- 80% Identity
- -