Basic Information

Insect: Drosophila santomea
Gene Symbol: -
Assembly: GCA_016746245.1
Location: NC:14221391-14224447[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 1.6e-05 0.00099 19.1 0.1 3 23 233 253 231 253 0.97

2 12 1.1e-05 0.00072 19.5 3.1 3 23 265 285 263 285 0.96

3 12 3.2e-05 0.002 18.1 2.5 1 23 291 313 291 313 0.99

4 12 2.9e-07 1.8e-05 24.5 2.3 1 23 319 341 319 341 0.98

5 12 2e-06 0.00013 21.9 0.4 1 23 347 369 347 369 0.98

6 12 1.8e-07 1.1e-05 25.2 1.0 1 23 375 397 375 397 0.99

7 12 4.3e-08 2.7e-06 27.1 2.5 1 23 403 425 403 425 0.99

8 12 7.4e-07 4.7e-05 23.2 5.9 1 23 431 453 431 453 0.99

9 12 3.1e-06 0.0002 21.3 0.3 1 23 459 481 459 481 0.98

10 12 3.2e-05 0.002 18.1 0.9 1 23 489 511 489 511 0.99

11 12 0.00038 0.024 14.7 3.2 1 23 521 543 521 543 0.97

12 12 2.5e-05 0.0016 18.4 1.9 1 23 548 570 548 570 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	1.6e-05	0.00099	19.1	0.1	3	23	233	253	231	253	0.97
2	12	1.1e-05	0.00072	19.5	3.1	3	23	265	285	263	285	0.96
3	12	3.2e-05	0.002	18.1	2.5	1	23	291	313	291	313	0.99
4	12	2.9e-07	1.8e-05	24.5	2.3	1	23	319	341	319	341	0.98
5	12	2e-06	0.00013	21.9	0.4	1	23	347	369	347	369	0.98
6	12	1.8e-07	1.1e-05	25.2	1.0	1	23	375	397	375	397	0.99
7	12	4.3e-08	2.7e-06	27.1	2.5	1	23	403	425	403	425	0.99
8	12	7.4e-07	4.7e-05	23.2	5.9	1	23	431	453	431	453	0.99
9	12	3.1e-06	0.0002	21.3	0.3	1	23	459	481	459	481	0.98
10	12	3.2e-05	0.002	18.1	0.9	1	23	489	511	489	511	0.99
11	12	0.00038	0.024	14.7	3.2	1	23	521	543	521	543	0.97
12	12	2.5e-05	0.0016	18.4	1.9	1	23	548	570	548	570	0.96

Sequence Information

Coding Sequence: ATGGATAGATCAGCAGTCGCCAGCCTGGGAAAGAACTGCCGAGCCTGTGCCGAACACTCATCCATACTGGTGGATCTCTTCTCCACGGAGATCTCTGATCCCCCCATTTGGGAAATGTTGAATTCAATTCTGCCGGAGATCTGTCGCGTGAAACGGGATGAAATGCCGCAGAAGATCTGTCCTACCTGCCTGGTGGCTGCTCAAAATGCCTTCCACTTCAGGCACAAGTGTGAGCAGAGTTTCCAGTTCTTTTCCCAGCTCCTCCACCTCGACAAATCTAACTCAAATCCGAGTAGATCCCGTTGCAAAAGAGGGGATAGGAATCCATTAATAGCCTTCGAGGTGGTCGGTTGCGAGGATCCTCTGGCCACAAATGCATCCGGAATGGATACTAATCGCCTTGATGTAAAGACTGATGTTGATGAGCCAACCGATACTGTAGCAACGAATGGTCAGGAGAGTGAACCGTTGCAAGAAGTTTTTGAAAtcaCGATGAGCGATATTAAAACGGAAGATGGATTATCCATTCAGGAGACATTTGAAGATGCCTTCGAAGATGAtagtgaaaataataatgacaGTGAAGAGGAGGATTCAGATCAATGGACAGCTGGTTCAACGGAAGACCATGATGAACTCTGGATTCCCGGCAATGGTGATCACAAAACAGTTGGTGGCAATAATCAATCACTGCTGTGCACCGAGTGTGGAGAAAGTTACTCGACGCAAAAGGCGTTGGCAAGACACGTTGCCAAGCATAAGGAGCAAGGTGATACACAAAAGCCGCACCTATGCGACTTCTGCGGTCGGGGATTCCGTACCAACGCCCAGCTAACGACCCATAGACGCCGTCATACCGGAGAGCGTCCTTTTAAATGCCCACTCTGCCCGAAAGCCTATACCCACGGTCCGACTCTTAAGTCGCATATGCACACCCACGACGAGGAAAAGGCTCACAGATGTCCGCAGTGCGAAAAGACCTTTTACACGAGAGGCAATCTGCGGGCCCATATACAGAGGCACACTGGCGAACGACCCTACAAGTGTCCCGACTGTCCACAGACCTTTGCCAAAAACTCTGGCCTTAAGTTGCACAGTCGGCTGCACAAGGAAGACCGACCCTATAAATGTGAGCTGTGCGGCAAGGGATTTGTGCAGAACCAGCATTTGATCACCCATTTGCGGGTCCACAACGGGGATCGCCAGTTCAAGTGTCCCGACTGCGATAAGTCGTTCTTCGAGAAATCAAACATGATGAAACATCAGCGCACCCATTCGGGTATAAAGCCATTTAAATGTGAGGAATGCGGCCAAGCCTTCTCGCACAACCATCACCTGAAGAGTCATCTACGCATCCATACTGGGGAAAAGCCCTACAAATGTGACCAGTGCGGCAAGGGGTTCAGTGCGAACCAGTCTCTGATGAAGCATATTCTTTGGCACGTGGATAATAATGATCGGCCATTCAAATGCTCTCAGTGCCCTAAAGCCTATGATACTCAGCAAAGCTTACGGGGTCACGAGAAGACGCATAAAAATCCGGATGAGCCAAAAACTCTGCACCAATGCCCGCACTGTGACGTAAGGTTTGCTTTAAAAAAGACCCTCGACAAGCATATCACAAGCCACAAGATTCGACCCCACCCATGCCCGCAATGTCCAGAAGGGTTTTTCTCCCAGAAGAGCTTAAAAAAGCACCTGCGATTTCACAACCTGACGTAA
Protein Sequence: MDRSAVASLGKNCRACAEHSSILVDLFSTEISDPPIWEMLNSILPEICRVKRDEMPQKICPTCLVAAQNAFHFRHKCEQSFQFFSQLLHLDKSNSNPSRSRCKRGDRNPLIAFEVVGCEDPLATNASGMDTNRLDVKTDVDEPTDTVATNGQESEPLQEVFEITMSDIKTEDGLSIQETFEDAFEDDSENNNDSEEEDSDQWTAGSTEDHDELWIPGNGDHKTVGGNNQSLLCTECGESYSTQKALARHVAKHKEQGDTQKPHLCDFCGRGFRTNAQLTTHRRRHTGERPFKCPLCPKAYTHGPTLKSHMHTHDEEKAHRCPQCEKTFYTRGNLRAHIQRHTGERPYKCPDCPQTFAKNSGLKLHSRLHKEDRPYKCELCGKGFVQNQHLITHLRVHNGDRQFKCPDCDKSFFEKSNMMKHQRTHSGIKPFKCEECGQAFSHNHHLKSHLRIHTGEKPYKCDQCGKGFSANQSLMKHILWHVDNNDRPFKCSQCPKAYDTQQSLRGHEKTHKNPDEPKTLHQCPHCDVRFALKKTLDKHITSHKIRPHPCPQCPEGFFSQKSLKKHLRFHNLT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00592517;
90% Identity: iTF_00619275; iTF_00504816; iTF_00592517;
80% Identity: -