Basic Information

Insect: Drosophila saltans
Gene Symbol: BCL11A
Assembly: GCA_018903575.1
Location: JAEIGH010000008.1:3748475-3764706[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.015 1.7 9.8 2.4 1 23 193 216 193 216 0.95

2 6 8e-07 9e-05 23.3 1.5 1 23 369 391 369 391 0.98

3 6 0.007 0.78 10.9 4.7 1 23 397 419 397 419 0.99

4 6 6.5e-07 7.3e-05 23.6 3.2 2 23 679 700 678 700 0.97

5 6 8.5e-06 0.00096 20.0 3.3 1 23 706 728 706 728 0.99

6 6 1.6e-05 0.0018 19.2 0.4 1 22 736 757 736 757 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.015	1.7	9.8	2.4	1	23	193	216	193	216	0.95
2	6	8e-07	9e-05	23.3	1.5	1	23	369	391	369	391	0.98
3	6	0.007	0.78	10.9	4.7	1	23	397	419	397	419	0.99
4	6	6.5e-07	7.3e-05	23.6	3.2	2	23	679	700	678	700	0.97
5	6	8.5e-06	0.00096	20.0	3.3	1	23	706	728	706	728	0.99
6	6	1.6e-05	0.0018	19.2	0.4	1	22	736	757	736	757	0.97

Sequence Information

Coding Sequence: ATGTATAACAAAATGCTGTCGATCAGTGAAGATCACGGATTCCGTTCGCTGAGTCATTCTGACTCCACAGTGAACGATGCCGTGGCCGCACAGGACATACTCACGTGCGGTGCCTGCCAAAAGACTTTCGCCCTCTCCGACATTGTCAAGATACACACACCGCCACCCAGTCCGGCTGATTTGTTGGCCGATGGAGCCAGCAGTACACCCAAACGGCTGGTAGATGAGAATGACAATACGACACCCAAAGACAGTGAAGCGGCCGCTTTAGAATCCACCACAGTGACCGGCAGTCCAAACAGTTGTCCCACCAATAGTAATCCAAATGAGCATCAATTGCCGGATGAAGCGGATGCTGTTAGGGACAGGGATAGCAGTTGTGAACTGGATGACGATGATGATGATGATGATAGGCCAACTAAGGTTAAAGAAGAACCATTTGGCGATGATGATGATGATGTCAATGCTGCTGATGAGCGGGTAGACTCGGCCATTGATTGCCCACCTCTGGCCAAGCGACCCAAAATGGAGCTTGTCGATGCCGAAGCCAATACAGTGCATACAGAGCCTAGCAACTACACCTGCTCCACATGCAAGACCCGCTATACATCCGCCTGGCGTCTCATTCAACATGTCCAGCATTCGCATGGCGTGAAAATCTATGTGGAGGCCACTGGGGGAGCCACTCTAACTCTGCTGCGCATGCCTCTGCCTCCGGCATTGGCCCAGGGTAATGTAGTTCCTAGTGTGTCGCCTCTATTTGGTCGTCCCACGCCTGCGGATCATTATCGCATGGAGCAGCTGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCACGACAAAAGCAATCGCCGCACTTTGCGAGCCCTTCACCCAGTAGCCAGCATCAGCATGGACAGCACCAGCATCCGCATCAGCAACTTTCCCACCAGTCGCGTCCTCATTCCCTGACGCCGCCAGAGAAGGCCAGTGAAACGGGTTCGGAGAATGGTGGCTTGGGCACTCCACGATCGGCCAGCACACCACCGTCGAAGCCAGGATCTGGTGGGGATCAGGCCAGCTGTTATGCCTGCAGCTATTGCGATAAGAAATTCCGCTTCGAGAACAACCTGATCATCCATCAGCGGACGCACACGGGCGAGAAGCCGTACAAGTGCACTGCCTGTGACTTTGAATGCTCCCACATACAGAAACTAATGAAGCATATGCGTGTTCATCGCAGTCCCGCCGAGAGTCAAGATGGGCACGATGGGCCCGATAATCAAGATGGCGGCAGCAATGCCGATTCTCTTGAAACAAATGAAGCCGATCAGGATGAGGATCCCAATCCCGAGGAGTCGGAAGAGGATGAGGATGCTGATGGAGATGTTGATGCCGATCTGGATGATGAGGATGACGAAGAACTTGACGATTGTGAGGAGATGAAATATGAGGCCGAAGATCTCAGTGTCAATAATCGGATTGATGGCAAGAGTCAGAGTCCCAAGACGACAAGTTCGGGTGCCACTTCGCTAGTGGGTGAGCTAATGGATAAATTTGGCTTGTCGAACATTGCCCAATACAGTGAGGCCTATAAGCAGGCTCTGCAAGAATCTGGTCGCAAGGATGCCTCTGCTGTTGCCGCAGCCGCAGCCGCTGCAGCGGACAATAATAATCGGGGCTCGGGATCAGGAGCTGGAACCGGCGCAACACCAAATGGCTTGCCAGCGGCAGCACTCCGTCTCCGCGATGAATTTGCCAAGAACTGTAATATGTTCCAACAACCGCAGGAGGCAACCGGACCAGCTCAGGTACCCCTATTTAATCCCTTCCCGAATCCCTTCGAGCTATCCAAGCGTATGAAAATGGATGGCGGTGATTGGTGGGGTATGTCTGCCCTTCATCGCAATGAGACCCTCTTCGAAAACCTCAAGCTAAAGCCTCTCGGTCTGGGAGGAGCCAACTCACTGCTGCAAGGTCCATTGCTGAAGAAGGAGAGTCGACAACGGAACGACACCTGTGAGTTCTGTGGTAAGGTATTCAAGAATTGCTCCAATCTGACAGTCCACAGACGCAGTCACACCGGCGAAAAGCCATACAAATGTGAGCTATGTTCCTACGCCTGCGCTCAGAGTTCCAAACTGACCCGCCACATGAAGACGCATGGCCGTACGGGCAAGGATGTGTATCGCTGCCGGTTCTGCGATATGCCATTCAGTGTCCCCTCAACGCTGGAAAAGCATATGCGCAAATGTGTCGTGAATCAGGGCAAGGCGGCGGCAGCAAATGCTGTAGCGGCTGCCCAAGCAGCCCAGGCGGCTGCCCAACAGATTCAAGCGGCGGCCCAACAGGCCCAACAGCAGCAACAGCAAATGCCGGCCCAAGCTCAACTATCACCGCCCTGCCCGCCCATGGGTGTGGGCTATCCACCGCAGTTTGTTGCCGGCCTTTCGCTGCCCGGCAGTGTAAGTGGAGACAATGACTCGAATGCCTCATCCAGCCTAAACGCTCATCCGATTTCGCTTAAAGAAGAGGCATGA
Protein Sequence: MYNKMLSISEDHGFRSLSHSDSTVNDAVAAQDILTCGACQKTFALSDIVKIHTPPPSPADLLADGASSTPKRLVDENDNTTPKDSEAAALESTTVTGSPNSCPTNSNPNEHQLPDEADAVRDRDSSCELDDDDDDDDRPTKVKEEPFGDDDDDVNAADERVDSAIDCPPLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVEATGGATLTLLRMPLPPALAQGNVVPSVSPLFGRPTPADHYRMEQLRLRQLAGTTSPGAGNIVNSSSPSPRQKQSPHFASPSPSSQHQHGQHQHPHQQLSHQSRPHSLTPPEKASETGSENGGLGTPRSASTPPSKPGSGGDQASCYACSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPAESQDGHDGPDNQDGGSNADSLETNEADQDEDPNPEESEEDEDADGDVDADLDDEDDEELDDCEEMKYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKDASAVAAAAAAAADNNNRGSGSGAGTGATPNGLPAAALRLRDEFAKNCNMFQQPQEATGPAQVPLFNPFPNPFELSKRMKMDGGDWWGMSALHRNETLFENLKLKPLGLGGANSLLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAANAVAAAQAAQAAAQQIQAAAQQAQQQQQQMPAQAQLSPPCPPMGVGYPPQFVAGLSLPGSVSGDNDSNASSSLNAHPISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00600547;
90% Identity: -
80% Identity: -