Basic Information

Insect: Drosophila saltans
Gene Symbol: ham
Assembly: GCA_018903575.1
Location: JAEIGH010000003.1:3180340-3212198[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.017 2 9.6 0.0 2 21 279 298 278 301 0.87

2 9 0.0028 0.32 12.1 0.2 1 23 308 331 308 331 0.91

3 9 1.5e-07 1.7e-05 25.5 1.8 1 23 337 360 337 360 0.96

4 9 9.3e-07 0.0001 23.1 1.6 1 23 366 388 366 388 0.97

5 9 6.1e-05 0.0068 17.4 3.6 1 23 394 416 394 416 0.97

6 9 0.00043 0.048 14.7 1.1 2 21 424 443 423 444 0.94

7 9 5.6e-09 6.2e-07 30.1 1.3 1 23 889 911 889 911 0.99

8 9 4.5e-07 5e-05 24.1 0.9 1 23 917 940 917 940 0.97

9 9 5.1e-05 0.0057 17.6 6.6 1 23 946 968 946 968 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.017	2	9.6	0.0	2	21	279	298	278	301	0.87
2	9	0.0028	0.32	12.1	0.2	1	23	308	331	308	331	0.91
3	9	1.5e-07	1.7e-05	25.5	1.8	1	23	337	360	337	360	0.96
4	9	9.3e-07	0.0001	23.1	1.6	1	23	366	388	366	388	0.97
5	9	6.1e-05	0.0068	17.4	3.6	1	23	394	416	394	416	0.97
6	9	0.00043	0.048	14.7	1.1	2	21	424	443	423	444	0.94
7	9	5.6e-09	6.2e-07	30.1	1.3	1	23	889	911	889	911	0.99
8	9	4.5e-07	5e-05	24.1	0.9	1	23	917	940	917	940	0.97
9	9	5.1e-05	0.0057	17.6	6.6	1	23	946	968	946	968	0.98

Sequence Information

Coding Sequence: ATGCCACCAATTGTTGGAACAGCTGCAGTAGGAACATCCACACCCTTGGAACATCAGCAGCAACAGCAATTACAGAATCACCCACCGCCACATCAACAGAATCAACAGCCACCGCCGCCAACGTTGCCCATTGATCCTGGCTTAGGTGGCTCCAGTTCATCTGGTTCTGGTTCATCTACAGCCAATATGGAACAATTATTGCAGGAAATGGCACGCCTGCGCGAACCTGCCTTTGATTTGGACATACGGGGTAATGGTGTCTTTGCCAAGGTGGATCTAAATCGTGCCACACGCTTTGGCCCATTTCCCGTTAAACTATGCCAACAGCCCAGCGATCCAAATTTTGCATGGAAGGTCCATGCTAGTACCTTTAGCGGCTGGCTAGAACCCTCATCCGATGTGATTGCCTGGTTAAAAAAAATACGCGCCGTACAGGAAGATGAAATTGAAGAGGCTAATTTACGAAGTTTCATAATGGGCGGTTATCTGTGGTACGAAACGAATCGTTTTATAGATGCTGGCAGTGAAATAATTGTCGATGGTGGACCAAAATCTCCCTACGAAATCAATGACAATTGCATAGGAGCTGCTGCAGCAGCGGCAGCAGCCGCCGTACTAGCCGCAGCAGGAGCAGGAGGCGGCGGCAGTGGTGGAGCTGGTGGTGGTGGTGCCAATGCCACCATTGTTAGTAGTTCATTAACCAGCGATGATCGCAGTGATCGTGATAACGGTTCCCTTTATGCCGGCGACGAATTTACCAAAGATAGAAAAAACTCATCGTTAATCAGTCAGAGCGATAGTGATTTCATAGACGACGAAAACGGTTTCGATATACGCTGTGAGGTCTGTGATAAAGTCTATACGGATTTAGGACGCTTGGACGATCATCTGGTCGGTGCACATCATTTCAAACAAGGTGAATTTGCCTGTGAACTTTGCTCTCAACGTTTCAGTCATCGTCCTTTGCTAATCAAGCATGGAGCTATAGCGCATAATAATATACGAAAGTATTCCTGCGAGAATTGTACCAAGGTATTTTGTGACCCATCGAATTTACAGCGTCATATTCGCGCCTACCACGTCGGAGCTCGCTGTCATCCGTGCCCGGAGTGCGGTAAAACATTTGGCACCTCATCGGGTTTAAAGCAACATCAGCATATCCATTCATCGGTTAAGCCCTTTGCCTGCGAGGTCTGCTACAAGGCGTACACCCAATTCTCAAATCTGTGCCGCCATAAGCGTATGCATGCCAACTGCCGAATGCAGATCAAGTGCTCCAAGTGCGGACAGAGCTTTAGTACGGTCACTTCGTTGTCCAAGCATAAGAAATTCTGTGATTCTACGGGCAGCTATCGCAGCAGTCAATCGAATCGTCTACATCATCTGCCATCGCATCATCATCATCATCAGCAGCAGTTGCCGTCGACGGCGACAGCAGGAAACCTACCGCCCAGTTCAACACAGCCTTCGGGCGGTGACTCTTCCGGTGAATCGACATCAGCTGCTGCTGCAGCAGCCGTAGCTGCCGCTGCCATGACAACGCCACCGAATCCATTTCTCATGTTCCGCGCTGGACCGCCCTTCTTTCCCGGCTTTCCGCCATACGGACTCTTTCCACAGAGTCCACTGCCGGGTGCCAATTTCCCATTGTTCTTTCCCAAGCCTCCGATGGATATGGGTTGCGGTATGCCGCCTTTAAGTTCACCTACTGCTGCAGCCTTCCGTCAGCAGGCATTGCAGTTTGGTTTAAAAATGGAGAATCGAGAGAAGACCCAAGAGCAGCATCTCAAGGACGAGGATCGGGAATCAAAGGCAGATGTAAGGTCCCTAAAATCGGAACCTTTACTCCAGGTATCCGAAGAGGAGGAAGAAGATTATAATAACGAAGAGGAGTCAAAGGATGAGAGTAAGGAACTCCAAAAGAAGGTCAAGACGGAAAGTGCATCCGAACCACAGGGTGAAGATGATAGGAAATCAATTGATATTGTTAGCACACCACCTCCAGCTGAATCCATCCTGGAATCGGGGAAACCAACAACGGCAACAGAACTGCCTTTGGATCTTTCCCTTAGTCGTAAACGTCGTAGCACTATAGCCTCACCGCTTTTTAGTCGCACATCTACCCCAGAGTTGGGTATTGAGGCGGATGATGAGACTGCAGAGTCCGAGCCGCCGGCAAAACTTCACAAGTCGCACAGTTCGGGGGAGAGTTCCACATCGCGACAGTCCTACAAGGGGAGTAGTCCTACGCCAAGTGCTTCGCCAGGACCGACACCATCGCCATCACCGCCCACAAGTACAGGGGGAGAGATGAGTAGCATGTCGGATAGCGGTACACCGGCTGCTGGCCTCTCAGCTGCAATGGTTAACTCAGCCATGGCCTGTCCCACAGCCATACATCCATTGCTGCTAGAGGAGATTTATAGATCACGCTCTATGGCCAGATTTCCACCACGTCCGTTTCCTTTTTTAGGCCCAGCGGGCGGACGGCAAAATATTGAGACAAAATCATCTCAATCAGGCAACAACAACATCATTAAGTATCCCCAATTGCCGTTTCCGCCCGAACCCTATTTCGATGATGTACCCATGGACAATGGCCTTACACCGCCAACCGATGGCTTTCCACCGCACTTGAATCGTTGTGTCAAGCTCAAGGATCGTTACACATGCAAGTTTTGCGGCAAAGTTTTTCCCCGATCGGCAAATCTCACACGTCATCTGCGAACCCATACCGGCGAACAACCGTATTCCTGCAAATATTGTGATCGAGCCTTCAGCATCTCCTCGAATCTACAGCGCCATGTGCGTAATATTCATAACAAGGAGCGTCCCTTTCGCTGCCATCTCTGTGATCGCTGCTTTGGCCAGCAAACAAATCTCGATCGGCATTTGAAGAAACATGAAACCGATGGCGGTTCCGGAGCCCAAGCTGGTTTCGGTGATTCACGGAGCTCGGCTGAGGCGGAATCTGAATGTTATTTTGATGAAATTCGCACATTCATGAATCGTGTTTATACGCCAACGAGTTTGGGTGGCGTTGATGGCGATACGGAGGAGTATGCGGGTAGTGATGATCAGATATCGGTATCGACTCGACGATCGGGAGCAACAACGAAAGAAGGGGGAGATGGTGCGAGGGAGGATGAAGAGATGGAGATTTCAGCATTGGTTTTGTTGTTGTTGTTGTTGCAACCAGGGGGCAATCAGTCAGCAGATGTTTTCATTTCCTACTCCGACGACGACGACGACGCTGCCGATGCCGCCGATGTCGAAGCACCCAAAGGTTTTAAAGGCGCAGATGTTTGGCACAGTTTCGTGTAG
Protein Sequence: MPPIVGTAAVGTSTPLEHQQQQQLQNHPPPHQQNQQPPPPTLPIDPGLGGSSSSGSGSSTANMEQLLQEMARLREPAFDLDIRGNGVFAKVDLNRATRFGPFPVKLCQQPSDPNFAWKVHASTFSGWLEPSSDVIAWLKKIRAVQEDEIEEANLRSFIMGGYLWYETNRFIDAGSEIIVDGGPKSPYEINDNCIGAAAAAAAAAVLAAAGAGGGGSGGAGGGGANATIVSSSLTSDDRSDRDNGSLYAGDEFTKDRKNSSLISQSDSDFIDDENGFDIRCEVCDKVYTDLGRLDDHLVGAHHFKQGEFACELCSQRFSHRPLLIKHGAIAHNNIRKYSCENCTKVFCDPSNLQRHIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCYKAYTQFSNLCRHKRMHANCRMQIKCSKCGQSFSTVTSLSKHKKFCDSTGSYRSSQSNRLHHLPSHHHHHQQQLPSTATAGNLPPSSTQPSGGDSSGESTSAAAAAAVAAAAMTTPPNPFLMFRAGPPFFPGFPPYGLFPQSPLPGANFPLFFPKPPMDMGCGMPPLSSPTAAAFRQQALQFGLKMENREKTQEQHLKDEDRESKADVRSLKSEPLLQVSEEEEEDYNNEEESKDESKELQKKVKTESASEPQGEDDRKSIDIVSTPPPAESILESGKPTTATELPLDLSLSRKRRSTIASPLFSRTSTPELGIEADDETAESEPPAKLHKSHSSGESSTSRQSYKGSSPTPSASPGPTPSPSPPTSTGGEMSSMSDSGTPAAGLSAAMVNSAMACPTAIHPLLLEEIYRSRSMARFPPRPFPFLGPAGGRQNIETKSSQSGNNNIIKYPQLPFPPEPYFDDVPMDNGLTPPTDGFPPHLNRCVKLKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYSCKYCDRAFSISSNLQRHVRNIHNKERPFRCHLCDRCFGQQTNLDRHLKKHETDGGSGAQAGFGDSRSSAEAESECYFDEIRTFMNRVYTPTSLGGVDGDTEEYAGSDDQISVSTRRSGATTKEGGDGAREDEEMEISALVLLLLLLQPGGNQSADVFISYSDDDDDAADAADVEAPKGFKGADVWHSFV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00600473;
90% Identity: iTF_00577940;
80% Identity: -