Dsal010625.1
Basic Information
- Insect
- Drosophila saltans
- Gene Symbol
- su(Hw)
- Assembly
- GCA_018903575.1
- Location
- JAEIGH010000049.1:1131-4330[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00046 0.052 14.6 2.2 1 20 123 142 123 144 0.94 2 12 1.9e-06 0.00021 22.1 0.4 3 23 195 216 193 216 0.93 3 12 0.77 87 4.4 0.1 1 23 222 244 222 244 0.88 4 12 3.8e-07 4.2e-05 24.3 2.4 1 21 251 271 251 272 0.95 5 12 4.2e-06 0.00048 21.0 1.0 2 23 284 305 283 305 0.96 6 12 7.2e-05 0.0081 17.1 5.3 1 23 316 338 316 338 0.99 7 12 5.6e-05 0.0063 17.5 0.9 1 23 344 366 344 366 0.97 8 12 6.4e-06 0.00072 20.4 0.7 1 23 372 394 372 394 0.98 9 12 1.4e-06 0.00016 22.5 2.2 1 23 400 422 400 422 0.97 10 12 1.6e-05 0.0018 19.2 0.5 1 23 426 448 426 448 0.96 11 12 2.9e-05 0.0032 18.4 0.2 1 21 456 476 456 480 0.92 12 12 5.3e-06 0.00059 20.7 0.4 3 23 500 521 498 521 0.97
Sequence Information
- Coding Sequence
- ATGAGTGCCTCCAAGGAGGGCAAAAGGGCGGACAAGGAGACTGTAGTGAGAATCGTGGACATTGACCAAATGTCCACTCCCAGGGATAGTAGCAAACGACCGGCCACACGTATGAAATTGCTTAACGATGTAACTGGAGCCGGCACTCTGACCAGTGTCAAGCCGGAAAAGCGTGGAGGTGCTCGGATTAAAATACTCAACGATGATCCCATCACGCCGCAAAGAGCGGAGAAACGAACAAGCTGTGGTAAAAAGACAGTCAGTCCCACCTCTGCCCCTGGCTCAACAGTAAAGATACTTAACGACAAGCGTTTCTCTTCGCCACATTCTTCCATGGAGACGAACAGCATTAAAGAAATTGTGGAACATGTCTGTGGCAAATGCTACAAGACATTCCGTCGTGTTAAGAGTTTGAAGAAACATTTGGAATTCTGTCGATATGACAGTGGCTATCATTTACGCAAGGCCGATATGTTAAAGAATCTTGAGAAGATCGAAAAAGATGCGGTGGTCATGGAGAAGAAGGACATTTGCTTCTGTTGCAACGAGAGCTACGATACTTTCCACTTGGGTCACATCAACTGCCCGGATTGTCCAAAGTCGTTTAAGACGCAAACTAGCTACGAGCGTCACATATTCATTACCCACTCGGAATTCAATACGTATCCTTGTTCAATTTGCAATGCAAACTTGCGCAGTGCCGCCCTACAGAAGCTGCATGAGGAGCAGCATAAGAATCGTGGCAAACCATATGCCTGTAAAATCTGTGGCAAGGACTTTACAAGATCCTATCATCTAAAACGTCATCAAAAATACTCGTCATGCTCGGCCAACGAGACTGATACTATGAGCTGCAAAGTGTGTGATCGAGTCTTCTATCGCCTAGACAATCTACGCTCCCATCTGAAACAACATCTGGGCACACAAGTGGTAAAGAAGCCCGAATACATGTGTCATGTGTGTAAGAATTGCTTCTATAGTTTGTCCACGCTCAACATTCACATACGCACCCATACGGGCGAGAAACCCTTTGATTGTGATTTGTGCGATAAGAAATTCTCTGCCTTGGTGGCTCTTAAAAAGCATCGACGGTATCACACAGGCGAGAAACCCTACAGCTGTACAGTGTGCAATCAATCTTTTGCCGTTAAGGAAGTCCTTAATCGTCACATGAAACGACACACGGGTGAGCGTCCGCACAAGTGCAACGAGTGCGGTAAAAGCTTCATTCAGGCAACACAATTGCGTACCCATTCCAAGGTTCATTTGCGTCCATACGCCTGTGATTTGTGCGATGAAAAGTTTAAGACGGAGAAGCAATTAGAACGGCATGTCAAGGATCACTCACGTCAGAGGCGTGCCGCTTTCTCCTGCTCTGAATGTAAGCGCAATTTCCGCAATGCCGATTTGCTCAAAGAGCATATGGACGCTGGCGATCATACACCCAAGCCGCAACGCGCAAAGCGCTCAAGCACCAAAATCACTGGACGCACTGATTGCGCTATATGTGACAAGAACTTTGATAGCACCGATACCTTGCGGAAGCATATACGCACAGTTCACGAGTGTGATCCAGATGATATATTTGGTGTTGATCCACCGTCTGCGAAGCGTAGCAAAGCTGTTGACAAATCCACCAATCTATTGGACGATGAGAATTCGGGAGAGGGATTAGCTCAAAATACCGCGGCCGGTTCGCTTATATCCAGTCAAACTGATGGCAACGGTGTGGTGGTTCGTGAGTTTATTGTGGATGAGGGTGATGGCACCGCCCAGACAATTATGCTTGAGAATGAGACGTATACCATATTGCCACTCGAAGGAGATATGGATGGTGGTAGCGAGCCAGCGGCAACGGGCAAAAAATCTAAACCGGAATCAAAGAAAAAGCAAACTACTGAGGTTTCGCCTGTCGTTAAGAAGGAGCAACGCAAATCTTTGGCTGCCAGTTTGGCCGAGGCCATTGCCGATAATATTGATGAAGAGGACTTTACCGGGGAAGTGCTAACCGAAGAGGATGTGAAGCTTAAAGAAAATGTGGCCAAATTGATTGATATGCTGGTGGATCCACCCATTCTAAAGAAATATGGCTGGCCCAATACCTCCGAGGAGACGGTGCTCTGCAAGGTGATTGAGAATTGTGGCCACGATCTGACCAAAAGTGGCGATAACTATGCAGAAATGGAATATGGTACACGTTTGAACACTAAGTGA
- Protein Sequence
- MSASKEGKRADKETVVRIVDIDQMSTPRDSSKRPATRMKLLNDVTGAGTLTSVKPEKRGGARIKILNDDPITPQRAEKRTSCGKKTVSPTSAPGSTVKILNDKRFSSPHSSMETNSIKEIVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCNESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNTYPCSICNANLRSAALQKLHEEQHKNRGKPYACKICGKDFTRSYHLKRHQKYSSCSANETDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVCNQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKVHLRPYACDLCDEKFKTEKQLERHVKDHSRQRRAAFSCSECKRNFRNADLLKEHMDAGDHTPKPQRAKRSSTKITGRTDCAICDKNFDSTDTLRKHIRTVHECDPDDIFGVDPPSAKRSKAVDKSTNLLDDENSGEGLAQNTAAGSLISSQTDGNGVVVREFIVDEGDGTAQTIMLENETYTILPLEGDMDGGSEPAATGKKSKPESKKKQTTEVSPVVKKEQRKSLAASLAEAIADNIDEEDFTGEVLTEEDVKLKENVAKLIDMLVDPPILKKYGWPNTSEETVLCKVIENCGHDLTKSGDNYAEMEYGTRLNTK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00600464;
- 90% Identity
- -
- 80% Identity
- -