Basic Information

Insect: Drosophila rufa
Gene Symbol: ush
Assembly: GCA_018153105.1
Location: JAECXS010000096.1:925561-930212[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0058 0.37 11.1 0.0 1 20 135 154 135 156 0.90

2 9 0.00028 0.018 15.3 0.7 1 23 212 234 212 234 0.98

3 9 0.095 6.1 7.3 2.4 2 21 276 295 276 296 0.92

4 9 0.043 2.7 8.4 2.9 2 21 674 693 673 694 0.93

5 9 0.008 0.51 10.7 0.0 3 21 746 764 744 765 0.91

6 9 0.0052 0.33 11.3 0.0 2 23 833 854 832 854 0.98

7 9 0.0024 0.15 12.4 1.2 1 23 860 882 860 882 0.99

8 9 0.00061 0.039 14.2 0.8 1 23 932 955 932 955 0.96

9 9 0.36 23 5.5 0.5 2 20 1079 1097 1078 1099 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0058	0.37	11.1	0.0	1	20	135	154	135	156	0.90
2	9	0.00028	0.018	15.3	0.7	1	23	212	234	212	234	0.98
3	9	0.095	6.1	7.3	2.4	2	21	276	295	276	296	0.92
4	9	0.043	2.7	8.4	2.9	2	21	674	693	673	694	0.93
5	9	0.008	0.51	10.7	0.0	3	21	746	764	744	765	0.91
6	9	0.0052	0.33	11.3	0.0	2	23	833	854	832	854	0.98
7	9	0.0024	0.15	12.4	1.2	1	23	860	882	860	882	0.99
8	9	0.00061	0.039	14.2	0.8	1	23	932	955	932	955	0.96
9	9	0.36	23	5.5	0.5	2	20	1079	1097	1078	1099	0.91

Sequence Information

Coding Sequence: ATGTGTTCGCTGCCACGAGATCCAGAAGGGACTAATACCGAGCCCGATCAGGACTTGGGCGAGACCGATCCGCGGCAGGAGGATGTGGAGGATGAACTGCCAGCTAACAGTCCCAGCACTCCGCCCAGGAGCAGCCCCTCCTCGCCGCAACTGATACCGAAGCTGGAGCAGCCTTCCACGCCTCCGTCGGAGGCGGAGCCATCGCCCTGTCCCTCGCCCTGTCCACCCACCACGCCCAAGCTGCCCAAGCTGCGCTGCAATGCGCTCCTGGCCTCCGATCCCGCCCTCAAGCCCGACGCCAAGGAGCTGACTCTCTCTCTCCCACCTCCCCCGCTCTCCATTAAGCCGGAGGCGCCATCGCAGGCGGAGGGCCTCGGGGAGCCGCTGATGAAGCCAGCCAGATTCATGTGCCTGCCCTGCGGCATCGCCTTCAGCTCCCCCTCGACGTTGGAGGCCCACCAGGCCTACTACTGCTCCCACAGGAACAAGGAGACGGACGAGGATCAGGCGGGCAGTGATAAGTCGGGAGCAGGGGGCGGAGCAGGCTCCACCGGGGCAGCAGGATCGGGAGGAGCAGGCTCCTCGGGAGGCTCGTCGGAGCCACCGGCCAAAATGGCCAGGACGGGCAAGCAGTACGCCTGCTCCCAGTGCTCGTACAGTGCGGACAAGAAGGTGTCCCTGAACCGGCACATGCGGATGCACCAGACCTCCCCGGCGGCACCCACCCTGGTCAGCCTGCCCAATCTCATCCAGAACGGAATCCCGCCGCCGGGCGTCACGCCCAACTCGCTGGAGGAGGGCTCTAGTCAACAGCAGACGGATCGCTACTGCAGCCACTGTGATATCCGCTTCAACAACATCAAGACGTACCGGGCGCACAAGCAGCACTACTGCAGCTCCCGGCGCCCCGATGGCCAGCTCACCCCCAAGCCGGACACCTCTCCCGGCGGCCCCGGTGGCGGCGGCGGCGTCGGACAAGGGCCGGCCTCCTCCTCCTCGGCCTCGGGCGGAGTCTGCGCCTCCGCGCTGTCCGCGGCTCCCGGCAAGCTTAGTCCGCAGCAGGCCAGGAACAACAAGACGCCCACGCCCGCCATGGTCGCCTTGGGGCACGCGGCAGCGGCAGCGGCGGCGGCAGCAGCAGCGGCCGCTTCTCTCCAGGCACCGCCTCATCCACCGCCGCCCTTCCTGGCCCTGCCCACGCACCCGATCATCATTGTGCCCTGCTCGCTGATACGGGCGGCCAGCTTCATCCCGGGACCACTGCCCACTCCCAACTCGGGAATTGTGAATCCGGAGAACACCTGCTTCACCGTGGACAATGGAACCATCAAGCCGCTGGCCACTGCCCTGCTGGGCACCAACCTGGAGCCAGAGCGACCCTCGGCGCCCTCATCGGCTGCTGAGGTGCCAGAGCCGAAGAGCAGTCCGCCGGAACCAAAGCGCAAGGAGGCGGGCGGCAGTCGTGAGTCCGCGCCCCTGGATCTCTCGCTGCGCCGATCGCCGATCTCTCTGAACTCGCTGAGCCTGCGGCAGCGACACCTGCGCACTGCCCTCCTGGACGTGGAGGAAGCGCTCCTCGGCGCTGTGGGCAAAGAGATCGTGGAAACCCCCTCCGGCGGCGGCGGCAGTGTCACTCCCGAGCAGATCGTGTGCGCTCCCTCGCTGCCCAGCAGCCCCTCGATGAGCCCCTCGCCCAAGCGCCGCACCATCAGTCCGAGGAGCTCGGGAGCCGGCAGCAATGCCTCCATGTCGCCACCCGGGCTGAGCGTGGTGCCCAGCCTGCTGGACATGCGCTCCATGCTGCCGGCGGACTTTGGCCTGCCCGAATCGCTGCTGGCCAAGACCAACCCGGAGCTGGCCCTCAAGCTGGCGGCGGCAGCAGCTGCAGCGGCTGCGGTGGCCGGAGGAGGCGGTCCTTCGCCGGCTCAGTCCAGTGCCGGCAATCCGGGGGGAAGCGGAGCAGGCTCCGGGGGCGGGCAGCAGCAGCAGCCGCAGATCTACGTGAAGCAGGGCGTGTCCAAGTGCAAGGAGTGCAACATCGTGTTCTGCAAGTATGAGAACTACCTGGCGCACAAGCAGCACTACTGCTCCGCCAGGAACCAGGAGGGATCTGCCGATGGGGATGTCAAGTCCGCTGTTTCGCCGGGAGCTGGGGGCTCCGGCGGCGGAGGGGGTGGAGGAGCAGAGGCTGCCACATCGGTGGAAACCACACCGGTGGCGTACCAGCAACTCATCTGCGCCGCCTGCGGCATCAAGTACACTTCCCTGGACAACCTGCGAGCCCACCAGAACTACTACTGCCCCAAAGGAGGCGCCACAGCGGCCGGGACACCAACAGATCCGGGACAGATGGCCCTGGTGGTGAAGGAGAAGTGCGGCAAGTGCAAGACCCTGCACGAACCGGGACTGCCCTGTCCGGCCCCGCTCACAAGCGCCCTCGCCGCACCAACATCCAACTCCTCCAACTCCTCGCAGCCCGCCTCCAACAGCCTGAACAAGTGTCCCGTGTGCGGAGTGGTCAGTCCCACGGCGGCGCTGGCCAAGAAGCACATGGAGATGCACGGGACGGTGAAGGCCTATCGCTGCAGCATCTGCCAGTACAAGGGCAACACGCTGCGCGGAATGCGCACCCACATCCGCACCCATTTCGACAAGAAGACGACCAGCGACGTGAACGAGGAACACTACATGACCTGCATCTTCGAGGAGGAGGAGGGTCGCGTGCTCAGCCAGGAGCTGAGCCAGCCCTCGGCTGCTGTCTCCCACGATTCCATGGAGCATCCGCCGCAGCTGTTCAACTGCGACTACTGCAACTACGCCTCCACCTACAAGGGCAATGTGCTGCGCCACATGAAGCTGCTGCATCCGCACGTGGCCATTATCAGCTCCCCCTCGATTTCGCCGGAGACCAGGGACCAGGATCAAGTGATCTCGAACTCCACGGCCAGCAACCAGCACTCGAGCACTTCCGATGGCTCCAATGGCGAGGCAGCGAGCTTCCACATCAAGTCGGAGCCCTTGGATCCACCCTCGTCGACGCTGAGCCTGGTGCAGGAGAACAACAATTCCTCGCCGCTACCCACCCTGACGCCACACATCAAGGCCGAGCCGATGGACATGGGCATGGACAGCCTGACCCTGCCCCAGCCGACGGTGGCATCGCCTCTGGGCAACAGCAGCTTGGCCGCCGCCGCTGCAGCCGCCTCGGTGGCTGCCGCCGAGGTGATGAAGAAGTACTGCTCCACCTGCGACATATCCTTCAACTATGTCAAGACCTATCTGGCCCACAAGCAGTTCTACTGCAAGAACAAGCCCCATCGCCCGGAGGCCAGCGACAGTCCCAGTCCGAACCTGGGGATCGGGGGCATTGGGAGCATCGGTGTGGTGGGCGGCGGCCAGCAGAAGAACAAGGAGAACCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MCSLPRDPEGTNTEPDQDLGETDPRQEDVEDELPANSPSTPPRSSPSSPQLIPKLEQPSTPPSEAEPSPCPSPCPPTTPKLPKLRCNALLASDPALKPDAKELTLSLPPPPLSIKPEAPSQAEGLGEPLMKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKETDEDQAGSDKSGAGGGAGSTGAAGSGGAGSSGGSSEPPAKMARTGKQYACSQCSYSADKKVSLNRHMRMHQTSPAAPTLVSLPNLIQNGIPPPGVTPNSLEEGSSQQQTDRYCSHCDIRFNNIKTYRAHKQHYCSSRRPDGQLTPKPDTSPGGPGGGGGVGQGPASSSSASGGVCASALSAAPGKLSPQQARNNKTPTPAMVALGHAAAAAAAAAAAAASLQAPPHPPPPFLALPTHPIIIVPCSLIRAASFIPGPLPTPNSGIVNPENTCFTVDNGTIKPLATALLGTNLEPERPSAPSSAAEVPEPKSSPPEPKRKEAGGSRESAPLDLSLRRSPISLNSLSLRQRHLRTALLDVEEALLGAVGKEIVETPSGGGGSVTPEQIVCAPSLPSSPSMSPSPKRRTISPRSSGAGSNASMSPPGLSVVPSLLDMRSMLPADFGLPESLLAKTNPELALKLAAAAAAAAAVAGGGGPSPAQSSAGNPGGSGAGSGGGQQQQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQEGSADGDVKSAVSPGAGGSGGGGGGGAEAATSVETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGATAAGTPTDPGQMALVVKEKCGKCKTLHEPGLPCPAPLTSALAAPTSNSSNSSQPASNSLNKCPVCGVVSPTAALAKKHMEMHGTVKAYRCSICQYKGNTLRGMRTHIRTHFDKKTTSDVNEEHYMTCIFEEEEGRVLSQELSQPSAAVSHDSMEHPPQLFNCDYCNYASTYKGNVLRHMKLLHPHVAIISSPSISPETRDQDQVISNSTASNQHSSTSDGSNGEAASFHIKSEPLDPPSSTLSLVQENNNSSPLPTLTPHIKAEPMDMGMDSLTLPQPTVASPLGNSSLAAAAAAASVAAAEVMKKYCSTCDISFNYVKTYLAHKQFYCKNKPHRPEASDSPSPNLGIGGIGSIGVVGGGQQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00594089;
90% Identity: iTF_00480437;
80% Identity: -