Basic Information

Insect: Drosophila rufa
Gene Symbol: -
Assembly: GCA_018153105.1
Location: JAECXS010000002.1:12814366-12820757[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0019 0.12 12.7 1.5 1 23 154 176 154 176 0.97

2 14 0.00019 0.012 15.8 1.7 1 23 403 425 403 425 0.98

3 14 2.7 1.7e+02 2.7 2.8 1 23 431 454 431 455 0.92

4 14 0.29 18 5.8 2.7 1 23 477 500 477 500 0.93

5 14 0.001 0.066 13.5 1.9 3 23 708 728 707 728 0.92

6 14 0.042 2.7 8.4 1.4 1 23 734 757 734 757 0.98

7 14 1.4 89 3.6 1.3 3 23 795 815 793 816 0.92

8 14 0.0025 0.16 12.3 0.4 1 23 837 860 837 860 0.97

9 14 0.00076 0.049 13.9 0.3 1 23 1042 1065 1042 1065 0.94

10 14 0.016 1 9.8 5.0 1 23 1077 1099 1077 1099 0.98

11 14 7.9e-07 5e-05 23.3 0.9 2 23 1105 1127 1104 1127 0.97

12 14 0.002 0.13 12.6 1.4 3 23 1136 1159 1135 1159 0.87

13 14 0.0024 0.15 12.3 1.4 1 23 1164 1186 1164 1186 0.96

14 14 0.0026 0.17 12.2 0.3 1 23 1192 1215 1192 1215 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0019	0.12	12.7	1.5	1	23	154	176	154	176	0.97
2	14	0.00019	0.012	15.8	1.7	1	23	403	425	403	425	0.98
3	14	2.7	1.7e+02	2.7	2.8	1	23	431	454	431	455	0.92
4	14	0.29	18	5.8	2.7	1	23	477	500	477	500	0.93
5	14	0.001	0.066	13.5	1.9	3	23	708	728	707	728	0.92
6	14	0.042	2.7	8.4	1.4	1	23	734	757	734	757	0.98
7	14	1.4	89	3.6	1.3	3	23	795	815	793	816	0.92
8	14	0.0025	0.16	12.3	0.4	1	23	837	860	837	860	0.97
9	14	0.00076	0.049	13.9	0.3	1	23	1042	1065	1042	1065	0.94
10	14	0.016	1	9.8	5.0	1	23	1077	1099	1077	1099	0.98
11	14	7.9e-07	5e-05	23.3	0.9	2	23	1105	1127	1104	1127	0.97
12	14	0.002	0.13	12.6	1.4	3	23	1136	1159	1135	1159	0.87
13	14	0.0024	0.15	12.3	1.4	1	23	1164	1186	1164	1186	0.96
14	14	0.0026	0.17	12.2	0.3	1	23	1192	1215	1192	1215	0.97

Sequence Information

Coding Sequence: ATGGCACTGAACAAACGGAATAACCCGCATCCGAACGCCCTTTCGGGCGTCGAGGAGGTGAACTACAAGTTTGCGTGTCGCTGCTGCCTAAAGGCGGACGCGGAGTTCGTCAAGCTGGAATCGGTGTCGGTGGCGCGCAGCCTGGACCCCGCCCGCGAGGATGATCAGATATCGCTCCTACGCTGCCTCGTCTTCTGCGTGCGCGCGGATAATGCGCCGGAGCTGCCGCAGTACATCTGCATCGAATGCAGCAAGAGCCTGCAGGTCGCCTACTACTTCCTGCAGAATGCGATGCGTGCCCACGAGATCCTTTGCCGCAAGTTGTGCCCCGGCAAGTCGAGCGCGGAGGGCAAGCGCTTCAATGGCACTATAGGCCAGAGGTTTCAGCTATCGCCGGCACTTAAGGAGTCTTCGGCGGCCACGTTGGGAGACAGGACGAGGCCGCCAAAAAGCCTAAAACACGAGTGCCAGGTGTGCGGCGAGGTCATCCACAATCGCATGGAGCTCAAGCAGCACATCCGCCAGCACGCAGAGGGAATCTCCTGCTTGAACTGCAAGATGTGCAACTTTACCACGCTCAAGCAGCGCCAGCTGCTGGAACACTATCGCTGCGATCACGCCATGACCCCCAGTCAGGCGGCGGAGCACGTCAAAGCGAGCCCACTGCCGCTATCCCCTCTCAAGGATGATGAGATCAAGGCTGTGTGCACGGTGGAGGACATGGAACTGCTGATACCCACAGTGCTCACGCCGGATGACTATGTCCACCCCACGATCGATACGGATCAGCTGCGCGACATTGAGCAGCACCTGGCCGCCAGCATGGGCGAGGTGGTGACGGGCGTGGACACCTTGACGTCCACATTGCCGCCCATGGACACGGCGCACAATGTGAGCATCGGCACGGAGTATCTGGTCCTGCCCGATGGCTCGCTGCAGCAGGTCAACGGAAGCGGCGTGGTCATTGAGTATATTGACGACAGCAAGCCGGCGCCGCCGCCGGCCAATCCTTCCCATGTCAACATCAGCCTCCAAAATCTCCTTGGCGGCCCAGACGAGCCAATGGACATCGATGTCAACGAGCTAATCGTCGAGGATATGTTGACGATGCCCAAGCCCACCATCTCCACTCCAGCTCAAGCTCCAGCTCTGGCTCCACCACCAGCCAAGCCAAAGTCAGCCGTTGGCGGCTCCCCAACCTACAAGCACAAGTGCAGTATATGCCCCAGAATGTTTTCCTCTGTGCCTCGCCTGAAATCTCACCAGTTAACCCACAGCAATTTGCCCAAGTTCTTCTGCGACCAGTGTGACTTCTACTCTCTGCGCAGCGTCGATCTCATCCAGCACTACAAGACTACGCACCACCGGGTGGATGAGAACGGCAGGCCCAGCGCCCAGAACGCGGCGCCGGAGGAGTCGGCCGGCGTCTATTCGTGCGACATGTGCCTCTTTGAGACGCGCTCCTGCAGCCAGCTGCGGGTCCACTACACGGAGCAGCACGACGTCCAGCCCACGGAGGTGCAGCTACGCCCCAGCTGGACCAACAGTGGCGGCGATGAGGCCAACACCAAGGAGCAGCCGTCGTCGGCCAGGCAGCAAGATCACGCCGACCTCCCGGTGGCCATTAAATATCCGCCGCCAAGCGCGGATACCCAAGTTCAAGTCCAGGTCCAGCAGCAGCAGCCATCCGCAACCATCACACAGGCTGTTGACAACATAAACGTTGTAGTGGGGGCCACGCCGCTCTTCTATGCGGCCACCTCTTCCAGCTCCGTGCCTGTGCAGACAGTGCAGGCAGTGGCAACGGTTCAGACGGTGCAGACTGTGCAGACTGTGCAGATGCCAGCGCTACCACCGGCGCTTCCAACCAAGGCGGAACCTACCGCTGAAAATAACAGCAATGCATTCGAAATCTTTCCGGAAATCTCACAAAGCAATCAGCAAGCGAACGCCGTCGAACCCGTTCCCGTTCAGCCCATGCCGGCCAACACATCCAATATCTCGATGTTTGGCGACATGCAGGATTTCATAGATAACACCGATGTGGCTGCCATATGCACGATACCGGCGGATGATATGCCCGTGGTGGATGGCGACGATATTCATCTGCAGAAGCCCTACTGCATTTACTGCAACAAGAAGTTCACCAGCCAGTACAAGTTCGAGAACCACATGTTCGTCCATCGGGGCCTGGCTCCCTATCGCTGCGAGCTGTGCACCAACCTGTACAACATGAAGCGCCTGCTGATCAGGCACTACAAGACCGTGCACAAGCGAATGCCCACCAGGGACATGGTCCAGGCCAAGGGCGACAAGGTGCTGGTGGCCCGCAACAACATTGAGAAGCTCTATCTGGATGCGGTCAAGAGTCCCATGGTCATGTGCGCCAAGTGTCCGTTTGAGTGCGAGTCGGATGCCGAAATGCGAAAGCATCTGAATGCCCATCATGGGATCAATGATGGATTGTCCATTCATGCCAACGAGGTCTTCATCATACGCAAATTGCCCTTCGAGTGCCCACGCTGCATTCGTTCGTTTGCTGCCAAGGGCACGCTCACTCGCCATCTGCAGCGCAGCCATTTGGTGGACACAATTATTGAGCTGCAAACGCCGCATTCCTCGGCGGCCACCACCACCATCACAACAACGACTTCCACGGCAACAGCAACAGCAGGAGATAAAGAACCTGCTAAGGTGATGTCGACGACGACGACGACGGCTGCTGCAGGCAATGCAGAGCAAGATGATGATGGAGCTGCAGCAGCGCCCGTAAGAAGGGGTCGCGTCGTGCCAGAGGAGGATGTGGATCCGGTGACATTGGACGCAGCCACGGCGGCGACAACGGCTGCCATAGCAGCAGCCATATCATCATCCGCTTCCGCCTCGCCCACGGCCACAACAACTGCATCCAACCTGTATCCCACTCCCACACCGTTTGATTTCGAGTATGACCTGATGAGCGATGCGCAGCGATCCCAGGTCTCGACACCCACCTCCTCCAATCCCCAGTTCGGATCCTCGCCCAGCAGCGGCCTGCTCAATGGCAGCGACAAGCTACTGACCACCGCCGCCCTGCCATCGAAGGGACTGCGCTCCACGCGGCGGCAGGCCCATTCCTCGATCTATGTCTGCAAGCTGTGCAACAAGTCCTTCGACGAGCTGGGCAAGCTGGTGAAGCACGAGATGGAGCTGCACTCGAACACGGAGCCGTCGCGATGGGGCTACCAGCACAAGTGCTCCATCTGCAGTACCAGCTACCGCACGCTGACGCTGCTCAAGTTCCACATGAAGCGCCACGTTAACCGCAAGTCGCAGTGCAAGCTGTGTCCCAAAACCTTTGCCACGAGCACGGAGCTGGAGCGGCACATGAAGGTCAAGCATTGCAGGGAGAAGACAATCGGGCCGTGTGCCATGGATGGCTGCGGCAAGATGTTTGCCTTCAAGCATCACATGATACGGCATCAGAATGCCTCCCACTTGAAGTCGCATCACGTCTGTGGCGTTTGCAAGAAGGAGCTGCCGACGGTGGCGCATCTGAAGAAGCACATGACACTGCACAAGGGCATGGTGACCTACAGATGTCCCGAGTGCGACCGCCCTTATTTGAGGCGAGGAAGACTTCAGAGCCATCTTCTGAAGATCCACAAGAAACGCATGACCGACGAGGAGATGGCCGCCATCTTTCGCGATATAAAAGTCTCTGCAAACCCACACGAGCTGAAGGTGAAGACCCGCAAGGGGCCAGTGGGGCGCCCCAGGAAGGTCTTGCCCAGAGTAGAGACGCCACTGGATGCGGCAGAGATGGCTGCAACGGGGACGGCGACGGTGACGGCTGCTGCATTAGATAACTCGAAATAG
Protein Sequence: MALNKRNNPHPNALSGVEEVNYKFACRCCLKADAEFVKLESVSVARSLDPAREDDQISLLRCLVFCVRADNAPELPQYICIECSKSLQVAYYFLQNAMRAHEILCRKLCPGKSSAEGKRFNGTIGQRFQLSPALKESSAATLGDRTRPPKSLKHECQVCGEVIHNRMELKQHIRQHAEGISCLNCKMCNFTTLKQRQLLEHYRCDHAMTPSQAAEHVKASPLPLSPLKDDEIKAVCTVEDMELLIPTVLTPDDYVHPTIDTDQLRDIEQHLAASMGEVVTGVDTLTSTLPPMDTAHNVSIGTEYLVLPDGSLQQVNGSGVVIEYIDDSKPAPPPANPSHVNISLQNLLGGPDEPMDIDVNELIVEDMLTMPKPTISTPAQAPALAPPPAKPKSAVGGSPTYKHKCSICPRMFSSVPRLKSHQLTHSNLPKFFCDQCDFYSLRSVDLIQHYKTTHHRVDENGRPSAQNAAPEESAGVYSCDMCLFETRSCSQLRVHYTEQHDVQPTEVQLRPSWTNSGGDEANTKEQPSSARQQDHADLPVAIKYPPPSADTQVQVQVQQQQPSATITQAVDNINVVVGATPLFYAATSSSSVPVQTVQAVATVQTVQTVQTVQMPALPPALPTKAEPTAENNSNAFEIFPEISQSNQQANAVEPVPVQPMPANTSNISMFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVLVARNNIEKLYLDAVKSPMVMCAKCPFECESDAEMRKHLNAHHGINDGLSIHANEVFIIRKLPFECPRCIRSFAAKGTLTRHLQRSHLVDTIIELQTPHSSAATTTITTTTSTATATAGDKEPAKVMSTTTTTAAAGNAEQDDDGAAAAPVRRGRVVPEEDVDPVTLDAATAATTAAIAAAISSSASASPTATTTASNLYPTPTPFDFEYDLMSDAQRSQVSTPTSSNPQFGSSPSSGLLNGSDKLLTTAALPSKGLRSTRRQAHSSIYVCKLCNKSFDELGKLVKHEMELHSNTEPSRWGYQHKCSICSTSYRTLTLLKFHMKRHVNRKSQCKLCPKTFATSTELERHMKVKHCREKTIGPCAMDGCGKMFAFKHHMIRHQNASHLKSHHVCGVCKKELPTVAHLKKHMTLHKGMVTYRCPECDRPYLRRGRLQSHLLKIHKKRMTDEEMAAIFRDIKVSANPHELKVKTRKGPVGRPRKVLPRVETPLDAAEMAATGTATVTAAALDNSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00609392;
90% Identity: iTF_00480379;
80% Identity: -