Basic Information

Insect: Drosophila rufa
Gene Symbol: zfh1
Assembly: GCA_018153105.1
Location: JAECXS010000001.1:29020982-29025211[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.4e-05 0.0015 18.6 1.0 1 23 151 173 151 173 0.97

2 15 0.00074 0.047 14.0 1.2 3 23 181 201 179 201 0.94

3 15 0.00024 0.015 15.5 0.2 1 23 277 299 277 299 0.98

4 15 0.00012 0.0076 16.4 0.8 1 23 305 327 305 327 0.98

5 15 1.3e-05 0.0008 19.5 2.3 1 23 359 381 359 381 0.97

6 15 0.0092 0.58 10.5 2.8 1 23 410 432 410 432 0.93

7 15 0.0096 0.61 10.4 1.3 1 23 438 461 438 461 0.97

8 15 0.023 1.5 9.2 0.4 3 19 470 486 469 487 0.95

9 15 0.00014 0.0088 16.2 5.6 1 23 496 518 496 518 0.97

10 15 0.041 2.6 8.4 0.4 2 23 524 545 523 545 0.96

11 15 8.1e-06 0.00052 20.1 1.0 1 23 554 576 554 576 0.98

12 15 0.00092 0.059 13.6 0.1 3 23 584 604 582 604 0.97

13 15 4.9e-05 0.0031 17.6 0.5 1 23 610 632 610 633 0.95

14 15 0.033 2.1 8.8 0.3 1 23 643 665 643 665 0.97

15 15 0.005 0.32 11.3 0.2 1 23 1198 1220 1198 1220 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.4e-05	0.0015	18.6	1.0	1	23	151	173	151	173	0.97
2	15	0.00074	0.047	14.0	1.2	3	23	181	201	179	201	0.94
3	15	0.00024	0.015	15.5	0.2	1	23	277	299	277	299	0.98
4	15	0.00012	0.0076	16.4	0.8	1	23	305	327	305	327	0.98
5	15	1.3e-05	0.0008	19.5	2.3	1	23	359	381	359	381	0.97
6	15	0.0092	0.58	10.5	2.8	1	23	410	432	410	432	0.93
7	15	0.0096	0.61	10.4	1.3	1	23	438	461	438	461	0.97
8	15	0.023	1.5	9.2	0.4	3	19	470	486	469	487	0.95
9	15	0.00014	0.0088	16.2	5.6	1	23	496	518	496	518	0.97
10	15	0.041	2.6	8.4	0.4	2	23	524	545	523	545	0.96
11	15	8.1e-06	0.00052	20.1	1.0	1	23	554	576	554	576	0.98
12	15	0.00092	0.059	13.6	0.1	3	23	584	604	582	604	0.97
13	15	4.9e-05	0.0031	17.6	0.5	1	23	610	632	610	633	0.95
14	15	0.033	2.1	8.8	0.3	1	23	643	665	643	665	0.97
15	15	0.005	0.32	11.3	0.2	1	23	1198	1220	1198	1220	0.97

Sequence Information

Coding Sequence: ATGAACAACCAGGGCTATGGCGGCATCCAGTGGATACAGCACCACCCCGCCGCGGGCGACTCCTCCGAGACGGACATTCTGGAGCACGACGACGCCGACGGCGACGATATGGTGAGCGGAGCGGACGGTGACCCTGATGGCGATGGGGATGCTGACCTGGACCATATGGCCGCCGAGAACCTGATCTTTATGGCGCGCGACGGCCAGCTGGGCGAGATTATCGCCGCCAACGAGGGCACTGTCCTGGTGACCGCCGATGGCACTACGGTGGCCTATGCAGAGTCCTTTGACGACGACGCCCAGGTGGTCACCGAGGAGGTGATCACCGACGACTGGGTGCAGCACCAAGGAGCCGAGCGCGTGGAAATCGCCGCCGAGCAGATAGCTGGCATCAGCAGCTCCCAGGAGCTATTGGACATGGAGCAGGACGAGTACACGGCCCTGCGACCCTACCCCTGCGACTTTTGCAGCCGACGCTTTCGGAAGAAGGCCAGCCTGAACAACCATATGCTGGCCCACCAGAACGACCGACCTCATCTCTGCAAGCTGTGCGGAGCGCGCTTCTCACGCCGGGCTGAGCTCATTAGCCACTTCAAGGCGCACGCCGAGGCCCAGGATGCTGCGGATGCCGAGGAAGCAGCCGCCGCCGCCGCTGAGGAGAGCAGCCAGTTCATCGTGATAACGGACAAGCCAGGCTCCAACGAGTTGCAGGACTACATGAACAGCGAGCCGGCGGTTCAGCCAGTGGTGCCAACATCGCAGCCCATGGCCATCGATCCTCCGCCTCCGCCGCAGCCAAACTTCCCGGTGCTGGACGACAGCAAGCCCTTTGTGTGTCAGCAGTGCGGACTGGCTTTTGCCCGGGAAAAGGCTCTGGTGTCGCACACTAAGAACCATCGCGTGGACTCCCCCTTCGAGTGCAACCAGTGCCAGGAGATGTTCTGGGACAACAGCAGCCTGCAGGACCACCAAAAGACGCACCAGTTCGAGGAGAGCAACTCGGAGTACGATCCCGCCTCCGGCGATGACAGCGCCAGCGAGACGACGGAGCCGGAGGAGCAGCTGTACGGGGAGTTCTACTGCAACGAGTGCGGCATTTCCTTCCATCGCCAGGACCTGCTGCGGCGCCATGCCAAGCAGCATCAGACGGCGACGGGAGATGGCAGCTGCTCGGATATCACGGCTAGCGGGGATCAGGCGGCGCAGACCAAGGATGGCAACGGCGGCCACTGCTGTCATACGTGCGGGAAGTCCTTTCCCAGTGCCCTGGAGATGCTTTCCCATGCCGAAATCCATGCCAGGTTTCCGCCCTTCAAGTGCGTCCTTTGCGGCATTAGCTTCTACGAGGAGCAGGCCATCAAGCGGCACCTGCACACCCGCCATCCCAACGAGCTGAAGGCCAACTCGTGCGTGCTCTGCGGCAAGGAGTGCCGCGACCGCAAGGCCCTGATCAAGCACGCCTGGGACCACTCGCGCGAGAAGTGCCACTCGTGCTCCAAGTGCGGCAAGAACTTTCACAACAAGGCGCGTCTGAAGCGGCACATGGCCTCGCACCGCGACAAGTCGGTGGTGTGCGAGGTGTGCCAGGAGGAGTTCCCCGACGGCCGGACGTTGTCCAATCACCGGCACTCGCACAGCACCACGTCGCCGGGCAAGCTCTTCCCCTGCCACGAATGCGGCAAGACCTTCGGATCGCGCAGCTCCCAGCAGATCCATGTGCGCATCCACACTGGGGAAAGGCCCTACGGCTGTCGCTACTGCTGGAAGGCCTTCGCCGATGGGGGGACCTTGCGCAAGCACGAGCGGATCCACACGGGCGAGAAGCCCTACGCCTGCTCTGTGTGTCCGCGGGCCTTCAATCAGCGGGTGGTTTTACGGGAGCACATCCGCTCCCACCACTCGGGGCTGGATTTGGCGCGGAACACGTACCACTGCACGGTCTGCTCCGAGGACCTGGCCTCCTCCAACGACCTCATACAGCACCTCATCCAGCACAGTGACTCGAACACCGCCAAGCAGCGTCAGCCGGTGACGGGACCGCGCAAGTACAAGCGTCGGCGCAAGCTGCAGCCCCACGAGATCGCGCACATGCGGGCGGAGCACAAGGACGAGGAGGAGGAGGTCCTCGGCGGCGAAGGCGAGCGTGAAGGCGATGGCGAAGCCGATGGAGATGGAGATGGAGATGAGTACGCCAGCGACTTGGACATCTGCGACTTTGACGTGGAGAATGTGGACGACATCTTTGAAATGGCCGAGTCCTCGCCCAGAAAGGAGAAACGCAAGCGGGCAACCCCAAAGGCAGAACCCAAACCTGTTGCCAATGGATCGGCGAAACCTGTCCAGGAGCAGAACAAGGCCAAGCTGCGGTATGACTCCACCAGCAGCCAGCAGTCGGATCGCATCTGGGAGGAGAAGTTCCTGCAGGACAGTCAGGTGGGTCTGTTCCAAATCGATTCGCTGGTGGTGGTCAACGACACCCACCTGCAGCCCGCGAGCTCGGCGGCCATGTCCAAGACGAGGCAACAGCAGGGCAAGGCAGGGCAGGCCAAGCAGCCCGCTGAAAGGGCAGGCAACTCCAATCCTTCGGCGGCAACCTCGGTTGCCACATCGTCAGCCTCCACCTCCACTTCCAGCAGTCGCAGCCGGAAGAAGACGGGAACCGTAAAAACGGCCGCTAGCAAAGCTCAACCTGCCAGCGGGAGTAGCTCCTCGCGACCCAGGATGATTCATACGGAGAAGGCCAAGGTGCCGATCAGGGGAGAGTTGGCCAAGAAGACGCGCTCCAAGACCTACATCACCCGCACGGAGACGACCAATCTCAGCAATCGCAGCAGAGCCTCCAACATCGTGGACGACTACGAGATCATATCGCCAGCCACTCATCCACCGAACCAGATCAGCTCCAGTCCGCTGCACATCAAGCAGGAGCAGGAGCAGCAGCACCACCGCGTCCAGATGATGTACGACGACAATCTGCTGATAGACGCCGCTCTGCTGCGGGAGAAGACCTACGATAAGTTCAACCCGAGCATTGTGAACGACCTGGAGGAGATCCTGCGCTCGCCGCTCAAGCACGAGCGGAATGCCCGCCTGCGATTCACCAGCGAGTCCTCGAACACGCCCCAGTTCCTGCCCGAGGAAGAGCAGAATCTGATCAAGATCGAGCCCACGTCCCCGGACTTAAGGGAGATGTTGGAGAGTCAGAGTCAGAAGGTAAGAGTGCCGAGTGGGAACACTCCATCGCCCTCTTCCTCCTCCGCCGCCAGAACCTCTTCTCGTCATCGTCCGATCACTGCCAATGGACCCAGGGCAGGGAGCAAGAGGTCCGGCGGCATTAGCAAGTTCTCACCTGCCTCCGGCGGGGCGGCCAAAAAAGTGAGCACTGCTGCCGGGAAGGTGAGCAGCAGCAGCTCGTCCTCGTACCTTAACTACGGGGTGGATGCCTACAATGTGAACGTACCTGCCAGCGCCAGCACTGCCGATGTGGGCAGCGGATTCTTCTCCATCTCGGAGGTCGTGTCCGCCGCCGATGCCGCTGATGCGGCGGCCAAGGCGGCGGCGGCCGGGAAGCCGGAGCGGAAAACGCGCAGTTTCGAGTGTGAAATGTGCTCGGCCATCTTCTATGACCGGGCCCAGCTACTGGACCATGTGCACATCCACATCTAG
Protein Sequence: MNNQGYGGIQWIQHHPAAGDSSETDILEHDDADGDDMVSGADGDPDGDGDADLDHMAAENLIFMARDGQLGEIIAANEGTVLVTADGTTVAYAESFDDDAQVVTEEVITDDWVQHQGAERVEIAAEQIAGISSSQELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEEAAAAAAEESSQFIVITDKPGSNELQDYMNSEPAVQPVVPTSQPMAIDPPPPPQPNFPVLDDSKPFVCQQCGLAFAREKALVSHTKNHRVDSPFECNQCQEMFWDNSSLQDHQKTHQFEESNSEYDPASGDDSASETTEPEEQLYGEFYCNECGISFHRQDLLRRHAKQHQTATGDGSCSDITASGDQAAQTKDGNGGHCCHTCGKSFPSALEMLSHAEIHARFPPFKCVLCGISFYEEQAIKRHLHTRHPNELKANSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDLARNTYHCTVCSEDLASSNDLIQHLIQHSDSNTAKQRQPVTGPRKYKRRRKLQPHEIAHMRAEHKDEEEEVLGGEGEREGDGEADGDGDGDEYASDLDICDFDVENVDDIFEMAESSPRKEKRKRATPKAEPKPVANGSAKPVQEQNKAKLRYDSTSSQQSDRIWEEKFLQDSQVGLFQIDSLVVVNDTHLQPASSAAMSKTRQQQGKAGQAKQPAERAGNSNPSAATSVATSSASTSTSSSRSRKKTGTVKTAASKAQPASGSSSSRPRMIHTEKAKVPIRGELAKKTRSKTYITRTETTNLSNRSRASNIVDDYEIISPATHPPNQISSSPLHIKQEQEQQHHRVQMMYDDNLLIDAALLREKTYDKFNPSIVNDLEEILRSPLKHERNARLRFTSESSNTPQFLPEEEQNLIKIEPTSPDLREMLESQSQKVRVPSGNTPSPSSSSAARTSSRHRPITANGPRAGSKRSGGISKFSPASGGAAKKVSTAAGKVSSSSSSSYLNYGVDAYNVNVPASASTADVGSGFFSISEVVSAADAADAAAKAAAAGKPERKTRSFECEMCSAIFYDRAQLLDHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00480304;
90% Identity: iTF_00480304;
80% Identity: -