Basic Information

Insect: Drosophila rufa
Gene Symbol: ZNF296
Assembly: GCA_018153105.1
Location: JAECXS010000001.1:17270078-17274521[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.0017 0.11 12.8 1.5 1 23 179 201 179 201 0.96

2 25 1.6 1e+02 3.5 3.7 1 21 208 228 208 230 0.84

3 25 0.0028 0.18 12.1 0.5 2 23 262 283 261 283 0.96

4 25 0.00059 0.038 14.2 0.8 1 23 354 377 354 377 0.94

5 25 4 2.5e+02 2.2 3.3 1 20 418 437 418 439 0.91

6 25 0.013 0.84 10.0 0.1 2 23 448 469 447 469 0.96

7 25 0.0035 0.22 11.8 1.3 1 23 551 574 551 574 0.97

8 25 0.0078 0.5 10.7 0.3 2 22 584 604 583 604 0.93

9 25 0.27 17 5.9 5.6 1 23 613 635 613 636 0.94

10 25 0.00081 0.051 13.8 1.4 2 23 651 672 650 672 0.97

11 25 4.6e-06 0.00029 20.9 4.3 1 23 679 701 679 701 0.98

12 25 0.0012 0.077 13.3 1.6 1 23 836 859 836 859 0.96

13 25 0.0015 0.096 13.0 0.4 3 22 868 887 866 887 0.94

14 25 0.022 1.4 9.3 1.4 1 23 896 919 896 919 0.93

15 25 8.2e-05 0.0052 16.9 2.3 2 23 938 959 937 959 0.97

16 25 8.5e-05 0.0054 16.9 0.4 1 23 966 988 966 988 0.98

17 25 0.028 1.8 9.0 0.0 2 21 1015 1034 1014 1035 0.93

18 25 0.0022 0.14 12.4 3.0 1 23 1081 1104 1081 1104 0.97

19 25 0.014 0.87 10.0 0.6 1 23 1141 1164 1141 1164 0.96

20 25 0.00026 0.017 15.4 1.5 1 23 1190 1213 1190 1213 0.97

21 25 5e-06 0.00032 20.8 0.2 2 23 1241 1262 1240 1262 0.95

22 25 0.0025 0.16 12.3 2.6 1 23 1268 1290 1268 1290 0.99

23 25 2e-06 0.00012 22.1 2.0 1 23 1296 1318 1296 1318 0.98

24 25 1.7e-07 1.1e-05 25.4 2.4 1 23 1324 1346 1324 1346 0.99

25 25 0.0012 0.074 13.3 0.1 1 21 1352 1372 1352 1376 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.0017	0.11	12.8	1.5	1	23	179	201	179	201	0.96
2	25	1.6	1e+02	3.5	3.7	1	21	208	228	208	230	0.84
3	25	0.0028	0.18	12.1	0.5	2	23	262	283	261	283	0.96
4	25	0.00059	0.038	14.2	0.8	1	23	354	377	354	377	0.94
5	25	4	2.5e+02	2.2	3.3	1	20	418	437	418	439	0.91
6	25	0.013	0.84	10.0	0.1	2	23	448	469	447	469	0.96
7	25	0.0035	0.22	11.8	1.3	1	23	551	574	551	574	0.97
8	25	0.0078	0.5	10.7	0.3	2	22	584	604	583	604	0.93
9	25	0.27	17	5.9	5.6	1	23	613	635	613	636	0.94
10	25	0.00081	0.051	13.8	1.4	2	23	651	672	650	672	0.97
11	25	4.6e-06	0.00029	20.9	4.3	1	23	679	701	679	701	0.98
12	25	0.0012	0.077	13.3	1.6	1	23	836	859	836	859	0.96
13	25	0.0015	0.096	13.0	0.4	3	22	868	887	866	887	0.94
14	25	0.022	1.4	9.3	1.4	1	23	896	919	896	919	0.93
15	25	8.2e-05	0.0052	16.9	2.3	2	23	938	959	937	959	0.97
16	25	8.5e-05	0.0054	16.9	0.4	1	23	966	988	966	988	0.98
17	25	0.028	1.8	9.0	0.0	2	21	1015	1034	1014	1035	0.93
18	25	0.0022	0.14	12.4	3.0	1	23	1081	1104	1081	1104	0.97
19	25	0.014	0.87	10.0	0.6	1	23	1141	1164	1141	1164	0.96
20	25	0.00026	0.017	15.4	1.5	1	23	1190	1213	1190	1213	0.97
21	25	5e-06	0.00032	20.8	0.2	2	23	1241	1262	1240	1262	0.95
22	25	0.0025	0.16	12.3	2.6	1	23	1268	1290	1268	1290	0.99
23	25	2e-06	0.00012	22.1	2.0	1	23	1296	1318	1296	1318	0.98
24	25	1.7e-07	1.1e-05	25.4	2.4	1	23	1324	1346	1324	1346	0.99
25	25	0.0012	0.074	13.3	0.1	1	21	1352	1372	1352	1376	0.91

Sequence Information

Coding Sequence: ATGCTTCCCTCGAATATCTGCCGAACTTGTGCGCTTCAGAACACGGATCTGCGGCCATTCTCTGATGACAATCTGCCGCAGCATCTGTGCACCGAATGCTTGGCGAGACTGGAAAGTGCCTACGCCTTTGTGGAGCAGGCCAGAAAGGTCAATGGAGAGCTGTTGGTTCGCTTGCGGGAGTGCCTGGACGAAATGCCCATAGATATTCCACAGGAGCAGCAGCAAATCAAAACCGAAGTAGACATCGATGAAGGGACTCTGAAGGAGGATGTGGATTCCACTGAAACATCGCCTGTGGAGTTCAAATGGCAGCCGGAAAGTGGCAGCGATGAGGAGTCTGGTGGAGCCGCAGCCGGTGAAGAGAATGAGGTCGAGAAGAAGCCCTATTCCCTGCGACGTAGCGCGCGCAAGATCAAGCAGCCGGTGGAGAGCGACAATGAGGACTTAGTACCCACGAAACCATCGCCCACCAAACGCCGTCGTGGGCGTCCGCCCGGCCCGGCCAAACGCCAGTCGATGACCTCCGACGGACGCCACGCCTGCAAGGTGTGCGGCAAGACCTTCTCCTGGTTCCGTGATATGCAACGCCATGCCCGCATCCACTACGAGAAATCCAATGCCTACGTGTGCGACACCTGTGGCAAGGGATTCCTGCGCAAGGACAAGTACACATTCCATTTGCGCTGCCACGAAAAGCGCGATGCCAAAGGGAGGGCTCTGGAGCTGGGAAGCGAGTGGCGTTTCGCCGAACGGCTGTACAGTTCCGGCAGGCTGAAGCGGATTGAGTGCAAGCTGTGTGGCCTCAAGTGTCCACGAATCGAGGAGCTAAGAACTCACATGGTCAGTCATCGGAACGTGGAGAGTTTGCGGCAGCTGAAGGAGGATAGCGATGTGATCAGGGAGCACTACGCAGATCAGCCTCTGGACGACGTCAGGCAACAGATTATCATGGACATTGCGGCGGGCGACTTGGAGAAGTTTGCTTCCGTCGTGAACTACCATGGCTACGAGCTGGGATTGTGTGACTCGGACGAGGAATCGGCCAGCGAGGAGGCCAAATATGAGTGTGAGGTGTGTAAGCTTCCCTTCTCCCGGAAACATCAAGTGGTGAGGCACACGCTGGAGGAGCACGCACACTCCTCGCCCTCAGAGCTTCCCTGGCAACGCTGCAGTCTCTGCAAAGTGGGTTTCCTCTGCTCCAGACTCTACGATTGCCATGTCCGCACCCAGTGTCAGAGCAAGGAAAGACGGCACTGCTGCCCCAAGTGCCCGGGGAAGTTTATGTGGCGGGAGAACCTGCAGAGACACGCCTGCTCCAAAGCGACCTTTGCCCGCCAGATCTCCTGCTCCCTGTGCGATGAATCGCTTCCCACTTTGGCCAAGTTGCGCATACACCTGGTTACCCACCAGAATGAACTGTGTGGCATCGATCCCAAGCACACTTCCACGTTCTTCCGGTCGTTCTACCCCGAGGGATTGGACTGCACGGCGGAGGAACTGGGTGTTCGGTTAGCTGAGGACTTTGAGGTGCAGGACTTTGATCGCTACTACAACGCCTGCACGGGCAGTGGCCAGGAGCTGGATCTCTTCGACTCCGAGACTGAGCAGAGCGGCGATGATGCTGGTGAGGAGCGTGAGAAGCCCGTCGCCCACACGTGTCTGCTGTGTGGCAAGGTCACAAACAGACTCCTGAGCTTGCTGCAGCACCAGAAAAGCGAGCATGCAGAGGCGGCGACAGAGTTGCTCTGTTCCTGCCAGGACTGCGGAGCTGGCTTTGTAAGCGACGCCCTGCTGCAACAGCACCGCCGTCGGGTGTGCGCCAAGAAGCACTTCCGCCACCACTGCCAGAGCTGCAATCTCCGATTCGTGTGGCCGAGCAACTACGAGCAGCATCTGAGGAGCCACCACAACCAGGCGGAGGAGGGGGAGCCACCGGAGGAGGGCAAACTGCAGTGCGAGGACTGCGAGAAGGTCTTCATCTGGCACAAGGATCTCACGCGGCACAGGCGCTTGCACCAGCCGCAGTCGGCGCAGTTCGAGTGTCCCCATTGCGATCGCAAGTTCCACCGCAAGGATGGCCTGAAGTCCCATCTGCGGGTGCACACGGAAGAGCAGCAGGTGGAGCAGCCCTTCACGTCCGACAGTGATCGGGTGCTGGCCCTGCTCACTCGTCCTCATGGCTGCAAGCAGATCCAGTGCATGATATGCCTCTCACGGCACTCCAAGATCTCCGATCTGCGCACGCACCTGGCCTCCCATCAGTACGGATTGAGCTTCTCCCCCGAGACCGATAGTTCCAGCGTCTCGAAGTCCCTGTATCCGGAACTGGGAACGACCTTGGGCAGGGATGAGCTGGCGGAGAGGATTATGGCTGATGTCGTCCAGGGACTAGAGCTAGATCGATTCACTTCCATTACGAATGAGGCTGGCCTCGAACTGAACTTGGATAGCAGCGAAACGGACACCGAGTCCGAGCAAGAGGAGGAAGACCCATCCAGCCAGAAGTACGCCTGCAGTCTCTGTCCCACGGCTGTGAAGAGGAAGCACCAACTCTATACACACCAAAGGGAAACTCATCAGTGGGAGGAGGCCCCCCTCGCTTGCCCGCACTGCCAGGCTAGGTTCGTCAACGAATCCCTGCTGGAGCATCACTCCAGGACCCTTTGCGGCAATCCCCAGAAGCGCTTCCAGTGCCGCAAGTGTCCGCTTCGCTTCCGCTGGCGTGAGAACCTCAAGCTCCACCTGTACCTGTCCCATCAGCAGGCTGAGATCCAAGCTACGGAAGACTCGCCGCCAGCGGAGGCCGACCTGCAGTGCCGGGAGTGCCAGCGAACGTTCAAGATGCAGAAGGATCTCACGCGGCACACGCTGATGCACGCCCGGGAGGCGACGATCTACCGGTGCCGCTGGTGTGCCCGCCGCTTCTACCGCTGGGCCAATCTCCTGCAGCACATCGCGCGCCACGGCATCCGGGCCAGCCAGTTGCACTACGCTGAGGCTCTGCTAGACTCCTACGGCAATCCAGGCGGGCAGAAAACGGTGGAATGTCGCGTGTGCAATGTGAGCTTCTCCAGCATCGCTGCCCTGCGTCTGCATCTGGAAACCATGCCGGCTGGGAGTCACCACGAGCTCTCCTCGCTGAAGAACTACTCGATCACCAACCAGATGGGCTTCGAGTTGGATCTCCAGGACTCGGAAACGGATGAGGAGCAGGGAAAGCCACCGGGGGTGCCTGCCTATTACACGTGTGGCATGTGCCAGCTGCGGTGCGTGCGGAAGTTCGAGCTGCAGCAGCACCAGCAGTCCATGCACCGACTGGAGAAGATCCCCGACGGCTGCGATCAGTGCATCTTCAAGAGCGTCTGTCCCGATCTCATTGCACACCACAAGAGGACGCAGTGCGGCAACAGGGAGAAGCAGTTCACCTGCGTTCGCTGCGGCTACAAGTTCATGTGGGAGTCGAACCTGCTCACGCACATGCAGCTGCAGCACGGAAAGCTGGACAATCTGGAGCCGGAGGAGAGCAAGGAGGCTGCGGCGGAGGAGCAGAAGCCTGGTAGCCCAGTCTTCCAGTGCGGCCTCTGCCCCAGGAAGTATAACCGCAAGGATCGCCTGACAGCGCACGTGAAAAAGTTCCACGGGCCCGATGGCAGGGGCCCCGAGGTGGTAAAGGTTCCTCCTCCCAACAGACCCACCTCGCCCAAGGAACCGAAGCGCTTCCTCTGCGCCTTCTGCGGCAAGGCGGTGAGCTCCTCCTCCAACCTGATCATCCACATGCGCCGCCACACCGGCGAAAAGCCCTTCAAGTGCGAGTTCTGCGCGATGGCCTTCCCCCGATCCTCGGACCTCCAGTGCCACCGACGCACGCATACGGGAGAGCGGCCCCACGTGTGCACCGTGTGCCAGAAGGGATTCGCCCGCTCCTACAAGTTGCAGCAGCACATGCGCATCCACAGCGGCGAACGGCCCTACAAGTGCACCTACTGCGAGAAGAGCTTCACGCAGTCCAACGACCTGACGCTCCACATCCGCCGACACACGGGCGAACGGCCCTACCAGTGCGGCGTCTGCGGGGAGCGATTCATCCAGGGAACGGCGCTGAAGAACCATCGCCTGCAGCAGGGCCACTACGAGGAGGGTCAGGGTTCTGGAGAGCCGGTCAGGCGCACGGTCTTGGAGCAGTTTACTGTATGA
Protein Sequence: MLPSNICRTCALQNTDLRPFSDDNLPQHLCTECLARLESAYAFVEQARKVNGELLVRLRECLDEMPIDIPQEQQQIKTEVDIDEGTLKEDVDSTETSPVEFKWQPESGSDEESGGAAAGEENEVEKKPYSLRRSARKIKQPVESDNEDLVPTKPSPTKRRRGRPPGPAKRQSMTSDGRHACKVCGKTFSWFRDMQRHARIHYEKSNAYVCDTCGKGFLRKDKYTFHLRCHEKRDAKGRALELGSEWRFAERLYSSGRLKRIECKLCGLKCPRIEELRTHMVSHRNVESLRQLKEDSDVIREHYADQPLDDVRQQIIMDIAAGDLEKFASVVNYHGYELGLCDSDEESASEEAKYECEVCKLPFSRKHQVVRHTLEEHAHSSPSELPWQRCSLCKVGFLCSRLYDCHVRTQCQSKERRHCCPKCPGKFMWRENLQRHACSKATFARQISCSLCDESLPTLAKLRIHLVTHQNELCGIDPKHTSTFFRSFYPEGLDCTAEELGVRLAEDFEVQDFDRYYNACTGSGQELDLFDSETEQSGDDAGEEREKPVAHTCLLCGKVTNRLLSLLQHQKSEHAEAATELLCSCQDCGAGFVSDALLQQHRRRVCAKKHFRHHCQSCNLRFVWPSNYEQHLRSHHNQAEEGEPPEEGKLQCEDCEKVFIWHKDLTRHRRLHQPQSAQFECPHCDRKFHRKDGLKSHLRVHTEEQQVEQPFTSDSDRVLALLTRPHGCKQIQCMICLSRHSKISDLRTHLASHQYGLSFSPETDSSSVSKSLYPELGTTLGRDELAERIMADVVQGLELDRFTSITNEAGLELNLDSSETDTESEQEEEDPSSQKYACSLCPTAVKRKHQLYTHQRETHQWEEAPLACPHCQARFVNESLLEHHSRTLCGNPQKRFQCRKCPLRFRWRENLKLHLYLSHQQAEIQATEDSPPAEADLQCRECQRTFKMQKDLTRHTLMHAREATIYRCRWCARRFYRWANLLQHIARHGIRASQLHYAEALLDSYGNPGGQKTVECRVCNVSFSSIAALRLHLETMPAGSHHELSSLKNYSITNQMGFELDLQDSETDEEQGKPPGVPAYYTCGMCQLRCVRKFELQQHQQSMHRLEKIPDGCDQCIFKSVCPDLIAHHKRTQCGNREKQFTCVRCGYKFMWESNLLTHMQLQHGKLDNLEPEESKEAAAEEQKPGSPVFQCGLCPRKYNRKDRLTAHVKKFHGPDGRGPEVVKVPPPNRPTSPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCEFCAMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGVCGERFIQGTALKNHRLQQGHYEEGQGSGEPVRRTVLEQFTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00491633;
90% Identity: iTF_00606462;
80% Identity: -