Basic Information

Insect: Drosophila rufa
Gene Symbol: -
Assembly: GCA_018153105.1
Location: JAECXS010000149.1:5347513-5360639[+]

Transcription Factor Domain

TF Family: THAP
Domain: THAP domain
PFAM: PF05485
TF Group: Zinc-Coordinating Group
Description: The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion. It features the conserved C2CH architecture (consensus sequence: Cys - 2-4 residues - Cys - 35-50 residues - Cys - 2 residues - His). Other universal features include the location of the domain at the N-termini of proteins, its size of about 90 residues, a C-terminal AVPTIF box and several other conserved residues. Orthologues of the human THAP domain have been identified in other vertebrates and probably worms and flies, but not in other eukaryotes or any prokaryotes [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 1.1e-15 2.1e-12 47.4 3.7 1 86 55 127 55 128 0.85

2 18 7.5e-12 1.4e-08 35.1 3.2 1 81 155 218 155 220 0.77

3 18 3.9e-09 7.4e-06 26.4 0.0 21 87 213 267 210 267 0.81

4 18 2.9e-16 5.5e-13 49.3 5.5 1 87 365 435 365 435 0.83

5 18 1.8e-15 3.5e-12 46.7 3.6 1 86 459 530 459 531 0.81

6 18 6.5e-13 1.2e-09 38.5 0.4 1 87 566 634 566 634 0.80

7 18 3.9e-11 7.5e-08 32.8 1.5 1 86 676 745 676 746 0.76

8 18 2.4e-17 4.6e-14 52.7 0.4 1 86 773 842 773 843 0.82

9 18 9.7e-13 1.8e-09 38.0 1.9 1 85 864 932 864 934 0.79

10 18 3.7e-15 7e-12 45.7 0.5 1 86 961 1032 961 1033 0.85

11 18 1.2e-12 2.4e-09 37.6 5.3 1 85 1107 1175 1107 1177 0.82

12 18 1.6e-12 3.1e-09 37.2 0.1 1 86 1200 1268 1200 1269 0.83

13 18 9.1e-14 1.7e-10 41.2 2.4 1 87 1413 1482 1413 1482 0.80

14 18 0.19 3.6e+02 1.8 0.1 26 58 1561 1590 1546 1613 0.77

15 18 4e-10 7.6e-07 29.6 0.3 1 86 1630 1710 1630 1711 0.72

16 18 0.34 6.6e+02 0.9 0.0 56 86 1744 1764 1727 1765 0.78

17 18 9.4e-11 1.8e-07 31.6 0.8 1 58 1790 1838 1790 1847 0.84

18 18 2.4e-10 4.6e-07 30.3 0.7 18 87 1856 1914 1845 1914 0.74

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	1.1e-15	2.1e-12	47.4	3.7	1	86	55	127	55	128	0.85
2	18	7.5e-12	1.4e-08	35.1	3.2	1	81	155	218	155	220	0.77
3	18	3.9e-09	7.4e-06	26.4	0.0	21	87	213	267	210	267	0.81
4	18	2.9e-16	5.5e-13	49.3	5.5	1	87	365	435	365	435	0.83
5	18	1.8e-15	3.5e-12	46.7	3.6	1	86	459	530	459	531	0.81
6	18	6.5e-13	1.2e-09	38.5	0.4	1	87	566	634	566	634	0.80
7	18	3.9e-11	7.5e-08	32.8	1.5	1	86	676	745	676	746	0.76
8	18	2.4e-17	4.6e-14	52.7	0.4	1	86	773	842	773	843	0.82
9	18	9.7e-13	1.8e-09	38.0	1.9	1	85	864	932	864	934	0.79
10	18	3.7e-15	7e-12	45.7	0.5	1	86	961	1032	961	1033	0.85
11	18	1.2e-12	2.4e-09	37.6	5.3	1	85	1107	1175	1107	1177	0.82
12	18	1.6e-12	3.1e-09	37.2	0.1	1	86	1200	1268	1200	1269	0.83
13	18	9.1e-14	1.7e-10	41.2	2.4	1	87	1413	1482	1413	1482	0.80
14	18	0.19	3.6e+02	1.8	0.1	26	58	1561	1590	1546	1613	0.77
15	18	4e-10	7.6e-07	29.6	0.3	1	86	1630	1710	1630	1711	0.72
16	18	0.34	6.6e+02	0.9	0.0	56	86	1744	1764	1727	1765	0.78
17	18	9.4e-11	1.8e-07	31.6	0.8	1	58	1790	1838	1790	1847	0.84
18	18	2.4e-10	4.6e-07	30.3	0.7	18	87	1856	1914	1845	1914	0.74

Sequence Information

Coding Sequence: ATGCTAATGAAGCGGGCATTTTTGCCGCATCTACGCTCAAGAACGAGCGTTCAGGAGAGCGGCTACAATAATATTTATAGTAGCAGCGACACCTCAATCCACGGTGCCCTCGCTGGACCGCAGGCACATTCTTCGACACTGGACGACTCCGAGGATGCGCTGTGCTGTGTGCCGCTGTGTGGGGTGCGGAAGAGCACAAGTCCCACATTGCAATTTTTCACGTTCCCAAAGGACGAGAAGTATCTCAACCAGTGGCTGCATAACCTTAAGATGTTCCACATACCCGCTTCGAGCTACCTTAGCTTCCGCATCTGCAGTATGCACTTCCCGAAGCGATGTATTAACCGCTACTCCCTGTGCTACTGGGCGGTGCCAACTTTCAACCTCGGCCACGATGACGTAGCCAATCTCTACCAGAATCGGGAACTTACCAACACCTTTACCACTGGCGAAGTGGCGCGCTGCAGCATGCCACATTGCACTAGCCAGCGAGGTGAGAGCAACCTTAAGTTCTACAACTTCCCGAAGGATATCAAAAGCTTGATAAAGTGGTGCCAAAACGCCCGACTTCCGGTGCAGGCGAAGGAGCCGCGACATTTCTGCAGCCGCCACTTCGAGGAGCGATGCATTGGCAAGTTTCGATTAAAGCCGGACGAAGTTCTTTTGCGTCGCTGGTGCTATAATCTTCGCCTCGATCCGGGAGTGTACCGCGGCAAGAATCACAAAATTTGCAGCGCCCACTTTATCAAGGAGGCACTGGGTCTCCGTAAACTATCTCCTGGTGCCGTGCCCACGCTTCATCTAGGCCACAACGATACCTTCAACATCTACGAAAACGAGCTATGGCCCCCGCCGACACCAACACCCTCAACTTGTCACTTGCAACAGCAACAGCAGTCATCACTTCACTCACTGCAACAGCAAATGCACAGCAAGTCCTACCAGCGTCGTTCCGTGGCATCCACTTCGTCGTCGGCGAGTTCGGCAGCTTCGCATTACGTGGACCCGGAGATGAACGCCTCTTACCGTCTAGCCATGTCCGCCTCCGCCAGTGGTTCTACGACGATAAACGCCAGCGATAGCATGGACGTCTGCTGCGTGCCTAGTTGCGAAAGCAAGCGCCACAATAATGAGAACATCACATTCCACACGATACCGCGACGGCCCGAGCAGATGCGCAAGTGGTGTCACAACCTTAAGATTGCCGAGGACAAGATGCATAAGGGCATGCGAATCTGTAGCCTCCACTTCGAGCCCTACTGCATCGGCGGCTGTATGCGACCCTTTGCGGTTCCCACTCTACATCTGGGTCACGATGACGAGGACATCCATCGCAATCCGGTCGTGATCAAAAAGCTAAACATTCGGGAGACATGCTGCGTGGCTGTGTGCAAGCGGAATAGGGACAGGGACCATGCCAATCTGCATCGCTTCCCCAGCAACGTGGCCTTACTGAGGAAATGGTGCGCCAATTTGCGGCGCTCTGTCCCCGATGGCAGTAAACTCTTCAATGATGCCATCTGTGAGGTGCACTTTGAGGATCGCTGCCTACGCAACAAGAGGCTGGAGAAGTGGGCAGTGCCTACTCTGGTTCTCGGACACGAAGATGTCGCCTATCCACTGCCCACACCGGAGCAGGTGACCGAGTTCTATGCACGGCCTACAGCTCCCAACAATGGCGAAGAACAGGGCGAGTGTTGTGTGGAGACCTGCAAGAGGAATCCTAGCGTGGACGACATTAAGCTTTACCGCCCGCCGGAGGATGCCGCCGTGCTGGCAAAGTGGGCGCACAATTTGCAGACGGAGGCTAACCAGCTGACGGGCATGAGGATCTGCAACCTGCACTTCGAGGCGCATTGCATTGGCAAGCGGATGCGACTGTGGGCAATACCAACTTTGAATCTAGCTGGCAACATCGAGAACCTCTACGAGAATCCAGAGCAATCGCTGCTGTACAGGCGGCGGACGACTCATTTGAAGACACAGCTGCCGTCAATCTCAGCAAAGCCCACCTGGGTGCCCAGGTGCTGTCTTCCGCACTGTCGCAAGGTCAGAGCCCTGCACAACGTTCAGCTTTACCGCTTCCCCAAGCTCAATCGCTCCACACTGGCTAAGTGGGCGCATAATCTCCAGGTTCCCATGGTGGGCAGTGCCCAGCGCAGGCTATGCTCGGCTCATTTCGAACCGCATGTGCTTAGCAAAAAGTGCCCGGTCCCGCTGGCCGTACCTACGCTCGACCTAAACTCACCATCCGGCCTGAAGATCTATCAGAATCCAGCCAAGCTAAAGGCCAGCAAACTGTGCCTGCAGCGGGTTTGCATCGTCGAGAGCTGCCGCAAGACGCGGGCGCAGGGCGTGCAACTATTCCGTCTTCCGCACAGTCCCACGCAGCTCAGGAAATGGATGCACAACATAAGGACGCGGCCACGGGCAGCTATGAGGGCTCAATACCGTGTCTGTTCCCGCCACTTTGAGACGCACTCATTCAATGGCCGCAGACTCAGCGCAGGTGCTATTCCGACTTTGGAACTGGGTCACGATGGCGACGACATCTATCCCAATGAAGCCCAGGCATTTGTGGAAGAACACTGTGCTGTCGAGGGCTGCGAGGCTTCCAAAGAGCACCCGGAGGTCCGACTCTTCCGCTTCCCCACCGATGACGACGATATGCTGTGGAAGTGGTGCAACAACCTCAAAATGAATCCTGTGGACTGCATTGGGGTACGCATCTGCAACAAGCACTTCGAGGCCGACTGTATTGGTCCCAAGCACCTGTACAAGTGGGCCATTCCCACAAAGGAGCTGGGCCACGACGACGCACAGATCGAGCTGATCCCAAATCCAAAACTAGAGGAGAGGTATGTGGATCCAGTCTTTAAGTGCATCGTACCCACCTGCGGAAAGACGCGACGCTTTGATGAGGTGCAGATGAACAGCTTTCCCAAGGATCCGGATCTGTTTCAGCGTTGGCGGCACAACCTGCGCTTGGAACACCTCAGTTTCCAAGAACGTGAGCGCTACAAGATTTGTAACGCTCACTTTGAGGAGATTTGTATTGGGAAGACTCGGCTGAACATTGGATCCGTACCTACCCTGGAGCTGGGTCATGACGATGAAGATGATATTTTCCAAGTGAATCCTGCGGAACTGCAGAGTAACTTATTCGGCCGACAACGTCGACTGTTACTTGAGGATTCCGGCGATGGGAGTGCGCAACAAGGGCTGTCCGAGACTAAAGATAACAGAAATACGGATCTGACGGCCACAGGCTCCAATTCCAAACAGGCTAAGATCAAGAGATCTATTTCGGATCTAAAGTGTTGTGTACACAGCTGTAGAAGAAGCCGTTTGGAGCACGGAGCACAGCTGTTTCCCTTTCCAACGGGCAAGCAGCAACACCTAAAGTGGCGTCATAATCTGCACCTGGAACCAGAGGAGGTGAACCGATCAACGCGAGTATGCAGTGCTCACTTCAATCGGCGTTGCATAGAGGGCAAACAGCTGAGGAGCTGGGCGATGCCCACCCAACAATTGGGTCACCACGACCAGCCGATATACGAGAACCCAAAGAATATACCTGGGTTTTTCACACCAACCTGTGCCCTGGGACACTGTCGCAAGAGGAGGAGTATTGATAACGATCTGCGTACCTATCGATATCCTAGAAGCGAAGATCTGCTGGAAAAATGGCGAGTTAATTTACAGCTGGCTCCGGATCAATGCCGTGGTCGGATTTGTGCAAACCATTTCGAGCCGCAGGTGCGTGGCAAGCTAAAGTTAAAGACGGGAGCCGTGCCCACACTAGAACTTGGACACGATGATGGATTAATCTATGACAATGAGGCTATAAAAACGGGTATGATGGAGGAAGAGGAAGGCCTCACCACAGAATTCCAGCGCCTGAAACCAAAAAAAGAGATGTTTGAAGTGGTTGAAGAGGACGTTGAAGAGAATGTTGGTGAAGAGCAGAACCTAGATTACCAGGACGATAATGCAGATGAGGATGACAAGGATGACCAGTATTTTGATCCTCTTGAACTGGTAGAGACCTTTGAACATCGCAGCAATGATGACGCCCAAGATGATGATGAAGAAGAGGGCCGAGTTCTGGACTCCCCCTCTGGTTACATGGTCAAGAAGGAGATAGAACAGCTTCCAAGCAGCCCACCTTCACCTTTACCCCGACGGCACCAAACTCTGCGTCAAGGCAAGCCTGCCAACAATGTGACGCCCATTTGTTGTCTAAAACACTGCAGGAAGGAGCGTACTGCCTTCCACCTGCTGAGCACTTTTGGCTTCCCAAAGGATCGCCAATTGCTGCTGAAGTGGTGTGCCAATCTGCATCTAAACCCGGATGACTGCGCCGGCCGGGTTTGCATAGAACACTTCCAGCCGGAGGTACTCGGTACCCGTAAGCTTAAGCAGAACGCGGTGCCCACTGTTAACGTTGGACATGATGAGCCGCTTAGGTACTCGTGTCATGGCGTGGATCAGAACCTCGAGGACCAAGACCCACAGCCACAGCATTCGGTTTTTCGGCTTTGGAGCCTGAAACACTGCCGCAAAAGGAAGCTAACGGAGCCACCGGATATTGCCCTGGCCAAGAGGAAACCGCTGGGAATGCCGATAATGAAGCGGGAATGGGAGATGGATAAGTCAAAGAAGATGACTCAAGCGGACAAGAAGCATCTGCGAAGTGCCTGGTTAAGGCACATGAACATAGAAGATCCGAAAGATGGAGCAGTCGCAGAGCTTTGCCCGCTGCACTATGTCATTCTCTACCAGCACAGTGCCAAAAACTATCCTGAGTATCACGATTCAAACCGATTGTTTCTTGATGATAACTACAAGGATGCGCGGAACAACCGGCGCGTAAGGATTGTGAGCTGTGTGATCAAGGGCTGCGACATGGTTAAGCCACGGGATGGGATACCATTGCACGGGATGCCGCAGAGCCTGGACATCCTGCAGATGTGGATACATAATGAGGACATGTGCCTTAAGTGGCAGCACAACACGCAAGTGCCATTCGATCCCTACTACCGCTGGCGTTACCGCATCTGCAGTGCCCATTTCCATCCAGTGTGTTTGGTCAACATGCGTCTAGTCCACGGAAGCGTTCCCACTTTAAAGCTAGGTCCCAAGGCTCCATCCGAACTGTTTGACAACGACTTTAATGCCATCAACCTAAGGCTGGACAAAAGGTTGACGGAGTCCAATGCCAATGTCCGGCACTTTGAGACAGAGCTGATTGGAGTGAGGCGTCTAATGCGTAACGCCATTCCCACAAAGCACTTAAATCCGCAAGGCGTTGACCAGGTCCGTACTAAAAAGGAGAAGAATCCTCAAGCCTCTATTATTCCCATCTGCTGCATGGCGGACTGCCACTACAATGGAAATGTGAAGCTGCACAAGTTTCCCAGTGATCCCACACTGCTTAAACAGTGGTGCCAGGCTCTTCGGCTCACCGACACGCAGCGGTATTTTGGCAAGCACATTTGTTCGATGCACCTGCCGATGAACGACACACTGAGCTGTGTTATCTGCGGTGGAGATAACATAGAGTTGCCGATGCTTGGGTTTCCGGAGAACCGCAACCAGCGCGCCAAATGGTGTTATAATCTCAAAATTGAGACAATACCAAAGTGGGACCACTCAAAGCACATATGCTGCCGGCACTTTGAGTCCTATTGCTTTGATAGGCCGGGTGAGCTACGTCCAGGAGCAGCTCCCACGCTCCATCTGAATCACAATGATACAAACATATTCTTCAGCGACTATGCCACTGGTCTTTCGTCCTCGCCAACACGCAATCAAATTAAAGACGAGCCGCTGGAATCGGAGTCTGACGAGATGCTGCTGGTGTAG
Protein Sequence: MLMKRAFLPHLRSRTSVQESGYNNIYSSSDTSIHGALAGPQAHSSTLDDSEDALCCVPLCGVRKSTSPTLQFFTFPKDEKYLNQWLHNLKMFHIPASSYLSFRICSMHFPKRCINRYSLCYWAVPTFNLGHDDVANLYQNRELTNTFTTGEVARCSMPHCTSQRGESNLKFYNFPKDIKSLIKWCQNARLPVQAKEPRHFCSRHFEERCIGKFRLKPDEVLLRRWCYNLRLDPGVYRGKNHKICSAHFIKEALGLRKLSPGAVPTLHLGHNDTFNIYENELWPPPTPTPSTCHLQQQQQSSLHSLQQQMHSKSYQRRSVASTSSSASSAASHYVDPEMNASYRLAMSASASGSTTINASDSMDVCCVPSCESKRHNNENITFHTIPRRPEQMRKWCHNLKIAEDKMHKGMRICSLHFEPYCIGGCMRPFAVPTLHLGHDDEDIHRNPVVIKKLNIRETCCVAVCKRNRDRDHANLHRFPSNVALLRKWCANLRRSVPDGSKLFNDAICEVHFEDRCLRNKRLEKWAVPTLVLGHEDVAYPLPTPEQVTEFYARPTAPNNGEEQGECCVETCKRNPSVDDIKLYRPPEDAAVLAKWAHNLQTEANQLTGMRICNLHFEAHCIGKRMRLWAIPTLNLAGNIENLYENPEQSLLYRRRTTHLKTQLPSISAKPTWVPRCCLPHCRKVRALHNVQLYRFPKLNRSTLAKWAHNLQVPMVGSAQRRLCSAHFEPHVLSKKCPVPLAVPTLDLNSPSGLKIYQNPAKLKASKLCLQRVCIVESCRKTRAQGVQLFRLPHSPTQLRKWMHNIRTRPRAAMRAQYRVCSRHFETHSFNGRRLSAGAIPTLELGHDGDDIYPNEAQAFVEEHCAVEGCEASKEHPEVRLFRFPTDDDDMLWKWCNNLKMNPVDCIGVRICNKHFEADCIGPKHLYKWAIPTKELGHDDAQIELIPNPKLEERYVDPVFKCIVPTCGKTRRFDEVQMNSFPKDPDLFQRWRHNLRLEHLSFQERERYKICNAHFEEICIGKTRLNIGSVPTLELGHDDEDDIFQVNPAELQSNLFGRQRRLLLEDSGDGSAQQGLSETKDNRNTDLTATGSNSKQAKIKRSISDLKCCVHSCRRSRLEHGAQLFPFPTGKQQHLKWRHNLHLEPEEVNRSTRVCSAHFNRRCIEGKQLRSWAMPTQQLGHHDQPIYENPKNIPGFFTPTCALGHCRKRRSIDNDLRTYRYPRSEDLLEKWRVNLQLAPDQCRGRICANHFEPQVRGKLKLKTGAVPTLELGHDDGLIYDNEAIKTGMMEEEEGLTTEFQRLKPKKEMFEVVEEDVEENVGEEQNLDYQDDNADEDDKDDQYFDPLELVETFEHRSNDDAQDDDEEEGRVLDSPSGYMVKKEIEQLPSSPPSPLPRRHQTLRQGKPANNVTPICCLKHCRKERTAFHLLSTFGFPKDRQLLLKWCANLHLNPDDCAGRVCIEHFQPEVLGTRKLKQNAVPTVNVGHDEPLRYSCHGVDQNLEDQDPQPQHSVFRLWSLKHCRKRKLTEPPDIALAKRKPLGMPIMKREWEMDKSKKMTQADKKHLRSAWLRHMNIEDPKDGAVAELCPLHYVILYQHSAKNYPEYHDSNRLFLDDNYKDARNNRRVRIVSCVIKGCDMVKPRDGIPLHGMPQSLDILQMWIHNEDMCLKWQHNTQVPFDPYYRWRYRICSAHFHPVCLVNMRLVHGSVPTLKLGPKAPSELFDNDFNAINLRLDKRLTESNANVRHFETELIGVRRLMRNAIPTKHLNPQGVDQVRTKKEKNPQASIIPICCMADCHYNGNVKLHKFPSDPTLLKQWCQALRLTDTQRYFGKHICSMHLPMNDTLSCVICGGDNIELPMLGFPENRNQRAKWCYNLKIETIPKWDHSKHICCRHFESYCFDRPGELRPGAAPTLHLNHNDTNIFFSDYATGLSSSPTRNQIKDEPLESESDEMLLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -