Drub006744.1
Basic Information
- Insect
- Drosophila rubida
- Gene Symbol
- -
- Assembly
- GCA_035046165.1
- Location
- JAWNOF010000021.1:7235899-7240344[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.0034 0.2 12.0 0.6 2 23 289 311 288 311 0.94 2 10 0.014 0.84 10.0 4.6 2 23 456 478 456 478 0.91 3 10 0.0064 0.38 11.1 2.3 3 23 569 590 567 590 0.94 4 10 0.029 1.7 9.0 1.1 3 19 700 716 699 721 0.93 5 10 0.00035 0.021 15.1 0.7 2 23 846 868 845 868 0.96 6 10 0.063 3.7 8.0 0.1 2 23 926 948 925 948 0.92 7 10 0.011 0.65 10.4 3.6 2 23 995 1017 994 1017 0.96 8 10 0.11 6.4 7.2 4.2 2 23 1031 1053 1030 1053 0.92 9 10 0.025 1.4 9.3 0.5 3 23 1112 1133 1111 1133 0.96 10 10 0.05 3 8.3 0.6 1 23 1246 1268 1246 1268 0.99
Sequence Information
- Coding Sequence
- ATGGCAGCATCCATATATGCCACCCCACCGCCGGATCTGAGCAGCGAGGACACAGCGCTCTCCGATGTCTCCAACTCATCCACACTCAACACAAAtcgcggcggcggcagcaacaacagcagcagcaacacgaccaccaacaacaacaacaacaataaccacagcagcaacaataacagcacgAATGAAGCCACAGTCACAACAAATGCTGCAGcgagcaccacaacaacaacaacggcggccaCCACAGCAGCCATGTCGCCACATTTGGACGCGGaatcgaagtcgaagtcgccAACGCTGCTGCAACAGGCAACGGGAAGCAACACAACTGTGTCACAGCAGTTGCAGACAGTGGACGACGACTCGCCAGACGCCGACGAGTGCGCCGAGGGAGTCGGCGAGGGCGGCGAGCTGGCGGAGCAGACGGCCATGGCCgcgatggcagcggcagcagcaaacgcagcagccatgcagctgcagctactcGAAGCTCTGAACGATGCGGCCAAGAAGCGACGCAAGCAACACAATCCCAGTCGCCTCGAGGCACTCAATTTGAGTGGCGGCGACGCGGATGCGGACgcagaaacagagacagacacagaggcagcagcagctggcgaggCAAGCGAGGGGGCAGCATCCAATGCGGTCATCGACTACGAGGAGAAGCTGTcgaagatgctgctgccgaaGTCGATCGTGAAGCTGAAGCAGACATTcgagttgctgcagcagcagaagctgcagcccGCAGACATATCAGAAGCAGACGGCGAGGAggacaagcaacagcagcaagaggacgaggagcacgagcagcaacagcatgcCAACAACATGATGAATCCCTATCAGACCTACTGCAAGCAATGCGGCGAGAACTTTGAGACCGAGTTCAAGCTCAGTCTGCACATGCTGCAggaccatcagcagcagccgcagccgcaacagtcacagcagcggcaacagttgcACGGCGAGCAGCCTTTGGAGCTGCTCAACTCCTTCAAAGTGAAGCAGGAGCGTGTCGACAGCCCcacgcagctggagctgcagcaacagcaggagcaactgcaactgcagcagcaacagcagcagcagcagcaactcgagcTGGCCAACGGACatgcgagcagcaacaaggaGCACGAGCTCTGGCTGCAGGCCatggcacagcagcagcagcaacaacagcagcagcatcaacagcagcaacagtctgCGCTGCCCGGCATGCCACCGGGCTTTGGCTTTCCGCCGGAGGCTGCCGCGCTGGGCTGGCCGCTGCTGGGCATGCCCGGCTTTGCTGGCGTCGAGGGACTCAATCGGCCGCCGCTGCGCATCTTCAATCCGGAGGCGTACTGCGAGCTGTGCAACAAGGAGTTCTGCAACAAATACTTTCTGAAGACGCACAAGGCCAACAAGCACGGCATCTTTGATCCGGCCGGCGAGCTGAGCgcgcccagcaacaacagcagcagcggcagcaacagcattctcaacaacaacagcagcctgagcaaccacaacaacaacaacaacaacagcagcagcagcagcagcggcggcggcaacagccaccacaacagcagcagcaacggcgccACTTCCAtgttccagcagctgcagatgccgCGCGAGCCGCCACCGCAAAAGCCCGAGCCGCAGCTGACGCCCCCCGCACCGCCCACCGTGCACTGTGACATCTGCTCGAAGCGCTTCACCAACGTCTTCGCTATGCGACGCCATCGCGCCAAGCAGCACGAGTCTGCcccgccagcaacaacagcagcagcagcagcagctgcaacagcggcacATTCGCCCACGCTGCAACAGCGACGCGGCAGCCCGAatgagtcgcagtcgccggTGAAGCTGGAGCCGCTGCTCGACTCGCCGCTGCCCGGGGACGCGAAGTCCTATCAGCTGCCCGACGGCTTTCGCGAGGACTTTACGCTCGAGCAGGAGGAGGTGCCGTTCGCGCCGCAGCCGCGCAAGTTgccgcagcagttgcagcagcaggcgcgcGACGCCAACTGTGCGCCGGAGAAGCTGCGTCGGCTGGGCGTGCTGCTGCCCGAGGCGTTCTGCGAGCTGTGCGGCAAGGAGTACGCCAATCGCTACTTTCTGCGCACGCACAAGTGGAAGCGCCACGGCATGTTTGTGCCGCCCGAGGAGCTGCCGCAGCAGTCGAGTGgcaaggaggagcagcagccgctcaTGTCCGCTGGCTGGCCCTTCATGCCGCTCAACCTAATGCTGGCCAAGGCAGCCGCCGaccaggagcagcaacagcagcaggagcagcaattGGCGGAAGCCGAgtccgagcagcagcagcagcaactggacgaggagcagcaggcggacgagcagcagccgagcaaaCGCATCAAGCTCGAGCCCTACGACGAACCAATGCCGGAGTCGAAGGCCGACAACAACTCCGTGATGGGCCTGCAGAATCTGCAGAAGCTGCAGtcgatgctgcagcagctcaacgaCTTCAACGGCAAGCGGCCGCTGCCCTGTCACCTGTGCGGTCGCGAGCTGGAGCATCAGTATGCGCTGCGTGCCCATCTGATGACCGAGCATGCTGGCCAACTGCTGCCCGAAGGACATCCCATGCtctaccagcaacagcagcagcagcagcagcagcaacagcagccgcagcagcaccagcCACAGTTGCCGCTAAAGCTGTCGCCATTGGGCGGCGCAGGGTCGCCGAGTGcggcggccacgcccacgccgaaCGAGCTGCGCTGCCTGCAGTGCGAACGCGACTTCGGCAGCGCTCAGGAATTCAAGCAACATATCGCCGAAGTGCATCTGGGTCGCATGCCCGGCAACAGCCCGTTGCGCGACGGCTTCTACACGCCCGAGCGCGCCActgtggccgccgccgcagctgcagcagctgcaacaggtCCGCCGCGGGCTGCGTACACGATCACGCCCACGTCCAGCTACTGCGAGATCTGCAACAAGGAGCTGTGCAACAAGTACTTCATGAAGACGCACATGCAGCGCATGCACGGCATCGAGATCGAGAACGGCGCACAGATTGGCGGCGTCGTCTGCAACATCTGCAACAAGGAGCTCTGCAGCAAGTACTTTCTGCGCGtgcacaagcacaacacacacggCATTATCGAGGACGGCGCTCCGTTGCCGCAGCCACGCGGTCAGAACGGCGTCAAGCtcgagtcgcagcagcagcaacagcaacagcagcagcagcaacaacagcagcagcagcaacaacacttggAAGCTGAGCTGCCACTCGCTGCTGAGTCCAGTGCCGCCAACGAGCTGTGCCCGCTGTGCGCTCGCCAGTTCCGCAGCTTCAAGTGGCTGCGCACGCACCTGCTGAACGAGCACGGCGCTGCCGGCGTCGAGCGGCTGCGCGAGCTGGAGCAGGCAACAGCTGGAGCGAGCGCTgccggcggcaacagcagcagcagcagcagccgaagcaaaCCGAACAGTCCCACGCTCAAGATACCCAATGGCAATGCCACTGCCGCCAACgcagccaccgccgccgccgctgccgccgccgtcgccgtggcCAACAATCTGCCGGCCAACAACCTGGCGCAGGCGCTGCAGAacgcacagcagcagttgttcGGTCAGATGCAGGGCCTGCCCAAGGgcatgccgctgccgctgccgttgccgggCATGTTCGAGCAGACGCCACGCTTCAAGGAGTACCAGTGCTCGCTGTGTCCGTTCACCACGCCCTACTACGCATTCCTCTTCATCCACGAGCGTTCGCATGCGCTGCTGaacaacggcggcgacggcgacgccaatCTGGCCGCCGAGGCGGAGCCGCCGCGCAGCGATCGCGATCGATCGTTTGCCTTGGTGCAGGGCAAGGCCAGGACCAAGTCGAGTCGCGACAGAAGCGATGCGGAGTCGCACGTCGAGCCCACCAACCTGtcgaccagcaacaacaacagcaacagcggcagcggcagcatcaagGCTGCCCGCACACCGCCCACGCCCACGGTCACGCCCACAACGCCACACGCCTCGCCCGGACTCGGCCAGGCGCATCCCTCGACTGTGGCCGCCTCTCCAAAGGCCCGCTCGGCGACTGTGACTCCGACGCCACGGCGCCGCTGCTCGACGAACAACAACTCCAAGCCGGGCACGCCCAACGGCATTGGCGCCCAACGTTCGGCGGCCACCTCGCCCTTCGAGGTGTGCAGCGAGCTggccaacggcagcggcaagccCGCCAGCTACGCCCAGCCCATCAAGTCGGAGGAGGCGTATCAGATGCAGGCCTTCCACTTGGCGCCGGCCGACGGCGATGCCGAGGGTCTCTTTGCGCCCGCTCTCGTCTATTTGCCGGTGCGCATGCGCGCCTCCGAGTCGACCACGCTGAGCTTCAGGCTGACTCCAGCCTAA
- Protein Sequence
- MAASIYATPPPDLSSEDTALSDVSNSSTLNTNRGGGSNNSSSNTTTNNNNNNNHSSNNNSTNEATVTTNAAASTTTTTTAATTAAMSPHLDAESKSKSPTLLQQATGSNTTVSQQLQTVDDDSPDADECAEGVGEGGELAEQTAMAAMAAAAANAAAMQLQLLEALNDAAKKRRKQHNPSRLEALNLSGGDADADAETETDTEAAAAGEASEGAASNAVIDYEEKLSKMLLPKSIVKLKQTFELLQQQKLQPADISEADGEEDKQQQQEDEEHEQQQHANNMMNPYQTYCKQCGENFETEFKLSLHMLQDHQQQPQPQQSQQRQQLHGEQPLELLNSFKVKQERVDSPTQLELQQQQEQLQLQQQQQQQQQLELANGHASSNKEHELWLQAMAQQQQQQQQQHQQQQQSALPGMPPGFGFPPEAAALGWPLLGMPGFAGVEGLNRPPLRIFNPEAYCELCNKEFCNKYFLKTHKANKHGIFDPAGELSAPSNNSSSGSNSILNNNSSLSNHNNNNNNSSSSSSGGGNSHHNSSSNGATSMFQQLQMPREPPPQKPEPQLTPPAPPTVHCDICSKRFTNVFAMRRHRAKQHESAPPATTAAAAAAATAAHSPTLQQRRGSPNESQSPVKLEPLLDSPLPGDAKSYQLPDGFREDFTLEQEEVPFAPQPRKLPQQLQQQARDANCAPEKLRRLGVLLPEAFCELCGKEYANRYFLRTHKWKRHGMFVPPEELPQQSSGKEEQQPLMSAGWPFMPLNLMLAKAAADQEQQQQQEQQLAEAESEQQQQQLDEEQQADEQQPSKRIKLEPYDEPMPESKADNNSVMGLQNLQKLQSMLQQLNDFNGKRPLPCHLCGRELEHQYALRAHLMTEHAGQLLPEGHPMLYQQQQQQQQQQQQPQQHQPQLPLKLSPLGGAGSPSAAATPTPNELRCLQCERDFGSAQEFKQHIAEVHLGRMPGNSPLRDGFYTPERATVAAAAAAAAATGPPRAAYTITPTSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVVCNICNKELCSKYFLRVHKHNTHGIIEDGAPLPQPRGQNGVKLESQQQQQQQQQQQQQQQQQQHLEAELPLAAESSAANELCPLCARQFRSFKWLRTHLLNEHGAAGVERLRELEQATAGASAAGGNSSSSSSRSKPNSPTLKIPNGNATAANAATAAAAAAAVAVANNLPANNLAQALQNAQQQLFGQMQGLPKGMPLPLPLPGMFEQTPRFKEYQCSLCPFTTPYYAFLFIHERSHALLNNGGDGDANLAAEAEPPRSDRDRSFALVQGKARTKSSRDRSDAESHVEPTNLSTSNNNSNSGSGSIKAARTPPTPTVTPTTPHASPGLGQAHPSTVAASPKARSATVTPTPRRRCSTNNNSKPGTPNGIGAQRSAATSPFEVCSELANGSGKPASYAQPIKSEEAYQMQAFHLAPADGDAEGLFAPALVYLPVRMRASESTTLSFRLTPA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00520940;
- 90% Identity
- -
- 80% Identity
- -