Basic Information

Insect: Drosophila rubida
Gene Symbol: hb
Assembly: GCA_035046165.1
Location: JAWNOF010000012.1:14218168-14220696[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.00021 0.012 15.8 0.2 1 23 262 284 262 284 0.99

2 6 0.011 0.64 10.4 3.6 2 23 292 313 291 313 0.97

3 6 0.0003 0.018 15.3 5.0 1 23 319 341 319 341 0.98

4 6 0.039 2.3 8.6 5.3 1 23 347 371 347 371 0.93

5 6 0.00024 0.014 15.6 0.4 1 23 789 811 789 811 0.96

6 6 0.0035 0.21 11.9 0.2 1 22 817 838 817 841 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.00021	0.012	15.8	0.2	1	23	262	284	262	284	0.99
2	6	0.011	0.64	10.4	3.6	2	23	292	313	291	313	0.97
3	6	0.0003	0.018	15.3	5.0	1	23	319	341	319	341	0.98
4	6	0.039	2.3	8.6	5.3	1	23	347	371	347	371	0.93
5	6	0.00024	0.014	15.6	0.4	1	23	789	811	789	811	0.96
6	6	0.0035	0.21	11.9	0.2	1	22	817	838	817	841	0.91

Sequence Information

Coding Sequence: ATGCAGAACTGGGAGACGAGCACGGCGTCGGCCAACTACGAGCAGCACAACGCCTGGTACAGCAACATGTTTGCCGCCAACATCAAGCAGGAGCCCATGTCGCACcaccagccgcagcagccacacgatagcaacaacagcaacgccagcagtcCGCGGCAATCGCCCCATCCGCCCAGCACTCAACTGGAGCAATACCTcaagcaccaacagcagcagcagcagcagcaacaacagcagcagcccatgGATACGCTGTGTGCGGCGGCCATGACGCCATcgcccagcaacaacgatCAGAACAGTCTGCAGCACTTCGAAGCCactctccagcagcagctgctacagcaacagcaataccAGCAGCACTTCCAggctgcacagcagcagcagcagcaacaacaacagcagcagcaccatcatcTCGCACTGGGCGGCTTCAATCCGCTGACGCCGCCAGGCCTGCCCAATCCCATGCAGCACTACTACGCCAGCAACATGCGCCCCAGCCCGCAGCCCACACCGACAGCAACGTCGGCCACGGCTGCCGGCGTGGCAGCCACGCTGCAGACGGGCGACAAACTGCAGGCGCTCACACCGCCGATGGATGTGACGCCGCCGAAGTCGCCGGCCAAATCACAGCAGTCGAACGGCGTGGAGGCGGAGAAGGAGCACGATCTGATGTCGAACTCCAGCGAGGACATGAAGTACATGGCGGAGTCGGAGGACGACGACACGAACATACGCATGCCCATCTACAACTCGCACGGCAAGATGAAGAACTACAAGTGCAAGACCTGCGGCGTCGTGGCCATCACCAAGGTGGACTTCTGggcgcacacacgcacccaCATGAAGCCCGACAAGATACTGCAGTGCGCGAAGTGTCCGTTCGTCACCGAGTTCAAGCACCACCTGGAGTACCACATTCGCAAGCACAAGAACCAGAAGCCCTTCCAGTGTGACAAGTGCAGCTACACTTGCGTCAACAAGTCGATGCTCAACTCGCACCGCAAGTCGCACAGTTCGGTGTATCAGTACCGCTGCGCCGACTGCGACTATGCCACCAAATACTGCCACAGCTTCAAGCTGCACTTGCGCAAGTACGGCCACAAGCCCGGCATGGTGCTCGACGAGGACGGCACCCCCAATCCCTCGCTCGTCATCGACGTCTACGGCACTCGGCGCGGCCCCAAAAGCAAGTCCGTCTccggcagcagctccagctgcagcggctccagcaagcgcagcagcaacgtcgccaacgcccagcagcaacagcagcaacaacagcaacagtctgTTGCGgtgccagcgacagcagccacatcacAGCTTTCCGCGGCGCTGCAGGGATTCTCGTTGCCAGCCGCATCGACAGTGGCGCCTCCGCCTGCAGCAGTCACAGCTGCAGTCGCCACACCTGCGGCAGCCATTTCGCCGCCATCGCCGGCCAAGAGCGTGGCCAGCCAGGAGCGCGAACAGCCGCCGAGTCTGCCGAGTGctttgctgccgccgttggcCAGTTTGCTGCAACAGAACCACAACATGGCCTTCTTCCCCTACTGGAATCTCAATCTGCAGATGctcgccgcccagcagcaggccgCAGTGCTCGCCCAACTGTCGCCACGCATGCACGACCAATtccagcaccaacagcagcagcagcagcagcagcaagcgcagcagccacatctGCAACACGAGCTGAGCGCTCAGAGCgacaacgaggacgacgaggagcaggACGATGAGTTTGAGCGCAAGTCAGTGGACTCGGCGATGGATCTGTCGCAAGGCACGCCCATCAAGGAGGAGATACCAGTGCACCAGCTGCCCCACAGCAGCCACATGAACCACATGGCCATGAATCTGAAGCTCAAGGACGAGGACACGCCgctgatcagcagcagcacagcctCGCGGCGCAAGGGACGCGTCCTCAAGCTGGACAcactgctgcagctcaagtCCGCCGCCATGTCATCGCCGGAACAGGCCCAAAAGCTGCCCACTGCCTCGTCGCCCATTGCCGGCAGCAATGCCGTCAAGCAGCTGGCAGATGATCCCTGCTCCGGTGCCAGTTCCGCCGACGAGTCGATGGAGGCCAGCCACGTGCCACAGGCGAATACCAGTGCCAGCTCGACGGCATCCAGCTCGGGCAACAGCtccaatgccagcagcaatgcaGCTCCACTGCCAGCCACTGCCTgcgcctccgcctccaccACCGCTTCCGTCTCAGTGTCGACGTCCGTTGTTGCCGCCCCCGCCACAGCCTCCGTCTCGAGCTCATCCTCGTcgacgggcagcagcagtggcagcggcagcggcaacggcagcagcaactcgccGGCCATCTACGAATGCAAGTATTGTGATATTTACTTCAAGGACGCCGTGCTGTACACCATCCACATGGGCTACCACAGCTGCGACGACGTCTTCAAGTGCAACATGTGCGGCGAGAAGTGCGACGGACCCGTCGGCCTCTTCGTCCACATGGCCCGCAATGCGCACTCCTaa
Protein Sequence: MQNWETSTASANYEQHNAWYSNMFAANIKQEPMSHHQPQQPHDSNNSNASSPRQSPHPPSTQLEQYLKHQQQQQQQQQQQQPMDTLCAAAMTPSPSNNDQNSLQHFEATLQQQLLQQQQYQQHFQAAQQQQQQQQQQQHHHLALGGFNPLTPPGLPNPMQHYYASNMRPSPQPTPTATSATAAGVAATLQTGDKLQALTPPMDVTPPKSPAKSQQSNGVEAEKEHDLMSNSSEDMKYMAESEDDDTNIRMPIYNSHGKMKNYKCKTCGVVAITKVDFWAHTRTHMKPDKILQCAKCPFVTEFKHHLEYHIRKHKNQKPFQCDKCSYTCVNKSMLNSHRKSHSSVYQYRCADCDYATKYCHSFKLHLRKYGHKPGMVLDEDGTPNPSLVIDVYGTRRGPKSKSVSGSSSSCSGSSKRSSNVANAQQQQQQQQQQSVAVPATAATSQLSAALQGFSLPAASTVAPPPAAVTAAVATPAAAISPPSPAKSVASQEREQPPSLPSALLPPLASLLQQNHNMAFFPYWNLNLQMLAAQQQAAVLAQLSPRMHDQFQHQQQQQQQQQAQQPHLQHELSAQSDNEDDEEQDDEFERKSVDSAMDLSQGTPIKEEIPVHQLPHSSHMNHMAMNLKLKDEDTPLISSSTASRRKGRVLKLDTLLQLKSAAMSSPEQAQKLPTASSPIAGSNAVKQLADDPCSGASSADESMEASHVPQANTSASSTASSSGNSSNASSNAAPLPATACASASTTASVSVSTSVVAAPATASVSSSSSSTGSSSGSGSGNGSSNSPAIYECKYCDIYFKDAVLYTIHMGYHSCDDVFKCNMCGEKCDGPVGLFVHMARNAHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00547606;
90% Identity: iTF_00562747;
80% Identity: -