Basic Information

Insect: Drosophila rubida
Gene Symbol: BCL11A
Assembly: GCA_035046165.1
Location: JAWNOF010000023.1:11186305-11201540[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.027 1.6 9.1 2.4 1 23 292 315 292 315 0.95

2 6 2.7e-06 0.00016 21.7 1.0 1 23 800 822 800 822 0.97

3 6 0.013 0.74 10.2 4.7 1 23 828 850 828 850 0.99

4 6 1.2e-06 6.9e-05 22.9 3.2 2 23 1144 1165 1143 1165 0.97

5 6 1.5e-05 0.0009 19.4 3.3 1 23 1171 1193 1171 1193 0.99

6 6 2.8e-05 0.0017 18.5 0.4 1 22 1201 1222 1201 1222 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.027	1.6	9.1	2.4	1	23	292	315	292	315	0.95
2	6	2.7e-06	0.00016	21.7	1.0	1	23	800	822	800	822	0.97
3	6	0.013	0.74	10.2	4.7	1	23	828	850	828	850	0.99
4	6	1.2e-06	6.9e-05	22.9	3.2	2	23	1144	1165	1143	1165	0.97
5	6	1.5e-05	0.0009	19.4	3.3	1	23	1171	1193	1171	1193	0.99
6	6	2.8e-05	0.0017	18.5	0.4	1	22	1201	1222	1201	1222	0.97

Sequence Information

Coding Sequence: ATGTACAACAAAATGCTGTCGATCAGTGAGGATCACGGATTCCGTTCGCTGAGCCATTCCGACTCCACAGAGAACGATGCCGTCGCCGCGCAGGACATCCTCACGTGCGGCGCCTGCCAGAAGACGTTCGCGCTGTCGGACATCGTCCGCTTCATACAGCACAAGGTGCTGCAGTGCAACAAGGAGAACTACGGCCAGTGCACCACACAGGCGCCCAGCATGGACCGCGACGCCGACGAGGGCCGACCGCTGAGCCTCGTCAACCGCCGCCCCTCCATCTCGGCGCCCATCACAAACGCCGCCAGTCGCAAGTCGGCGCCCGGCGCCAGCTCCCTGCCGCCCGCGGCTGCCAGCGGCCCCGCAAGTGCTGCTGCCTCGGCCGCCGCAGCGGCTGCCacggcggcggctgccacagcggccgctgctgctgcggctgcggctgcggctgccacggcGGCAGCGAGCGGCTCACGCATCCACACACCGCCGCCCAGTCCGGCGGATCTCCTCGCCGAcggcgccagcagcacacCCAAACGCCTGGTCGATGAGAACGACAATACGACGCCGAAGACGGACGGCGACGGCCTCAACCTGGAGCAGTCGGCGAGCAGTCCGCGCGGCCCCTCGAAGCAGCCGCACATCGGACGCAGCGACGACTGCCGCCTGGAGGAGGACGACGGCCTCGTCGAGCCcgagcacgacgacgacgacaagccCAAGGTCAAGCAGGAGCCCACctacgacgacaacgacaacgatcacgatcacgatcacgatcacgacgacgaggagcagcGGCCGCTGGCGAAGCGGCCCAAGATGGAGCTGGTCGACGCCGAGGCCAACACAGTGCACACAGAGCCCAGCAACTACACGTGCTCGACGTGCAAGACCCGCTACACATCCGCGTGGCGCCTCATCCAGCACGTGCAGCACTCGCACGGCGTCAAGATCTACGTGGAGGCCAGCGGCGGCGCCACACTCACCGTGGCCACGCCCGCCGCCCTCAACGCAGCCGCCACCGCGGCGGCCGCGcacgccaacagcagcagcagcagcagcagcctccacatcaacagcagcagcgccagcgccagcccCAATCGCAGTCTCAGCCCcacggccgccgccgccgccgctgccgccgcagccgctgtgggcgtgccactgccgctgcacGCTCTGATGGCGCAGGCCGTGGCCTCGCAATCCGTCTCGCCCGCCgcgaagcgcagcagcagcaacagcaacaacagcaaccacaaccacaacagcaacaacaacaacaacaacaacagcagcagcaacaacagcagcagcagcagcagcaacaactgctcgTCGGTCGCGGCCGCAGCAGCGTTGGCGGCcaacacgagcagcagcagcagcaacagccacgccagcaacagccactcacccacacagcaactgctgcagcagcagcagcgcgtgcaacagcagcagcagcaacaacagcaacagcagcagcagcagcagcagcagcagagcatgGCCTCGGCCATGGCGGCGGGCATGCGGCATCAtccgctgctggcgccgcccGAGGCGATGCACGCGAATCCgttccagctgctgcgcatGCCGCTGCCCCCGGCGCTGGCGCAGAGCAGTGTAGTTCCTAGCGTGTCGCCGCTGTTCGGCCGTCCCACGCCCGCCGACCACTACCGCATGGAGCAGCTGGTGAGCGAGCAGTTTCGCCACCACGGCTTCAACctggctgccgccgccgccgccgcccaggcGCAGTTCAAcgccagcaaccagcagcagcaacaacagcagcccgCTCAGGGCGTTGCCGTCAATGTTCCTAGTGCCGTCGAGCAGCGGCCGCCgtcgagcaacagcagccagcgtGGCTCTGTGCCGCCCgcctcgctgccgccgccatcgcTCAGctcccagcagcaacagcagcagcaacagcagcagcaacagcagcaacaacagcagcagcagcagcagcagcagcaggcggccgCCGTGAGTCCGGCGTCGGTGAGTTTGGAGCCGCAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCACGACAGAAGCAATCGCCGCGCTTTGCGAGCCCCTCGCCCAGCTCCGCGACGCCCACGCCGCGTCCCCACTCGCTGACGCCGCCCGAGAAGCTGGCCGCTGGCAGCGAGAACGGCGCCCCCTCCACCACGACGCCCGGCAGCAGCCTCACGCTGCCCAGCACACCGCGCTCGGCCAGCACGCCGCCCAGCAAGACGGCCACTGCCACAGGCaacgcaactgcagctggcacgGAGGCGGAGGGCGAGCTGGAGGCGAACTGCTTTGCGTGCGGCTACTGCGACAAGAAGTTCCGGTTCGAGAACAACCTGATCATCCACCAGCGCACGCACACCGGCGAGAAGCCGTACAAGTGCACGGCCTGCGACTTCGAGTGCTCGCACATCCAGAAGCTGATGAAGCACATGCGCGTCCACCGCAGCCCCGCCGAGGGTcacgacggcggcagcagcagcaacggcggcgacaacaaccAGGACGGccacgacggcggcagcaatgcCGACTCGCTCGAGACGAACGAGGCCGATCACGACGACGATCCCAACCCCGACGAGTCCGATGAGGAgctcaacgacgacgacgtcgatgcTGATGGTgagggcgacggcgacggcgagggcgagggcgacgaggacgaggacgaggagctGGAGGACTGCGACGACGTCGACTACGAGGCCGAGGACCTGAGCGTCAACAATCGCATCGACGGCAAGAGCCAGAGCCCCAAGACCACCAGCTCCGGCGCCACCTCGCTCGTCGGCGAGCTGATGGACAAGTTCGGGCTGTCGAACATCGCCCAGTACTCGGAGGCGTACAagcaggcgctgcaggagTCCGGCCGCAAGGAGGCCGCCgccgtggccgccgccgccgccgccgccgccgcagccgctgccgttgacaacaacaatcggcAGTCTGTGCAGGCGGCTGGCGGTGCGGCCGGCGCCGCTGGTGGCGCTGCGGGCGCCCAGCCGCTGGCGGACAAGCTGAACGGGCTGCCGGTGGcggcgctgcggctgcgcgACGAGTTCGCGAAGAACTGCAACATGTTCCAGCCGCAGGCGCAGGAGGGACCGGCCCAGGTGCCGCTGTTCAATCCGTTCCCCAACCCCTTCGAGCTGTCCAAGCGCATGAAGATGGACGGCGGCGACTGGTGGAGCATGTCGGCGCTGCACCGCAACGAGGCGCTCTTCGAGAacctgaagctgaagccgctGGGCCTCGGCGGCGCCAACTCGCTGCTGCAGGGTCCGCTGCTCAAGAAGGAGAGCCGGCAGCGCAACGACACCTGCGAGTTCTGCGGCAAGGTGTTCAAGAACTGCTCCAACCTGACGGTGCACCGGCGCAGCCACACCGGCGAGAAGCCGTACAAGTGCGAGCTCTGCTCCTACGCCTGCGCCCAGAGCTCCAAGCTCACCCGCCACATGAAGACGCACGGCCGCACCGGCAAGGACGTCTACCGCTGTCGCTTCTGCGACATGCCCTTCAGCGTGCCCTCCACGCTCGAGAAGCACATGCGCAAGTGCGTCGTCAACCAGGGCAAGGCGGCCGCGGCCGCTGCCAACGCGGCCAACGCTGTGGCCGCCGCCCaggccgctgccgccgcccagcaaCTGCAGGCGGCCGCccaggcgcaacagcagcagcagcagcagcaacagttgcccgCTCAGTCGCAGCTGTCGCCGGCGTGCCCCATGGGCGTGGCAGTCGGCTTCCCGCCGCAGTTCGGCTCGCTGGGCGGCCACAATCTGTCGCTGCCGGGCAGCGTGAGTGGCGACAACGACTCGAACGCCTCGTCCAGCCTGCCAGCGCACTCGATTTCGCTCAAGGAGGAGGCATGA
Protein Sequence: MYNKMLSISEDHGFRSLSHSDSTENDAVAAQDILTCGACQKTFALSDIVRFIQHKVLQCNKENYGQCTTQAPSMDRDADEGRPLSLVNRRPSISAPITNAASRKSAPGASSLPPAAASGPASAAASAAAAAATAAAATAAAAAAAAAAAATAAASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKTDGDGLNLEQSASSPRGPSKQPHIGRSDDCRLEEDDGLVEPEHDDDDKPKVKQEPTYDDNDNDHDHDHDHDDEEQRPLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVEASGGATLTVATPAALNAAATAAAAHANSSSSSSSLHINSSSASASPNRSLSPTAAAAAAAAAAAVGVPLPLHALMAQAVASQSVSPAAKRSSSNSNNSNHNHNSNNNNNNNSSSNNSSSSSSNNCSSVAAAAALAANTSSSSSNSHASNSHSPTQQLLQQQQRVQQQQQQQQQQQQQQQQQQSMASAMAAGMRHHPLLAPPEAMHANPFQLLRMPLPPALAQSSVVPSVSPLFGRPTPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNASNQQQQQQQPAQGVAVNVPSAVEQRPPSSNSSQRGSVPPASLPPPSLSSQQQQQQQQQQQQQQQQQQQQQQQQAAAVSPASVSLEPQQMDFYSQRLRQLAGTTSPGAGNIVNSSSPSPRQKQSPRFASPSPSSATPTPRPHSLTPPEKLAAGSENGAPSTTTPGSSLTLPSTPRSASTPPSKTATATGNATAAGTEAEGELEANCFACGYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPAEGHDGGSSSNGGDNNQDGHDGGSNADSLETNEADHDDDPNPDESDEELNDDDVDADGEGDGDGEGEGDEDEDEELEDCDDVDYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAVAAAAAAAAAAAAVDNNNRQSVQAAGGAAGAAGGAAGAQPLADKLNGLPVAALRLRDEFAKNCNMFQPQAQEGPAQVPLFNPFPNPFELSKRMKMDGGDWWSMSALHRNEALFENLKLKPLGLGGANSLLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAAANAANAVAAAQAAAAAQQLQAAAQAQQQQQQQQQLPAQSQLSPACPMGVAVGFPPQFGSLGGHNLSLPGSVSGDNDSNASSSLPAHSISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519433;
90% Identity: -
80% Identity: -