Drub010204.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila rubida
Gene Symbol
HIVEP2
Assembly
GCA_035046165.1
Location
JAWNOF010000022.1:1393094-1404562[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 4e-05 0.0024 18.0 0.5 1 23 228 250 228 250 0.98
2 8 0.0003 0.018 15.3 2.9 1 21 256 276 256 280 0.89
3 8 0.027 1.6 9.1 0.1 1 19 906 924 906 927 0.93
4 8 2.7e-06 0.00016 21.7 2.0 1 23 1619 1641 1619 1641 0.99
5 8 1.1e-05 0.00067 19.8 5.3 1 23 1647 1671 1647 1671 0.92
6 8 8.7e-05 0.0051 17.0 3.4 2 23 2160 2181 2160 2181 0.97
7 8 0.00078 0.046 14.0 1.2 1 23 2187 2211 2187 2211 0.91
8 8 0.0025 0.15 12.4 2.7 1 23 2232 2256 2232 2256 0.92

Sequence Information

Coding Sequence
ATGACGCTacagcatgtggcaagcagcgcagcagcagcagccgtggacaccagcagcaaccacGTGGTCgccggcaacggcagcggcaacggcaccACAGCAACCATGGCCCCGgcggtggccagcagcgaTGAGGCAGCCACGGCGGCCAGCATCGGCGACTGGACGAACAGCACGAACCTGCGCTACCTGCACAAGAAGTTCAAGCGCTTGGCCAGCACCACCGAGGCGGAGGCGGCCGTGGTTGATGCGGTGCGCACCACCTCGCTCTCCTCCAACAGCTCCCTCTCGCCACCGCCAGTCACAGCCCCATCGTCGACTGTGGCGACGTCGTCAGTGCCATTGCTGAACGGACACGAgttcgccagcaacaacaacaacatcaacaacaacaacagcagcagcgtgcacGACgagagccacaacaacaacaacaacggtggCAAGCacgtggctgctgcggcgcctAGAACGCGCACGCcgctcagcaacagcaacagcaacaacaatgcaacgTTGTCGCCCGCCACATTCGCACAGCACCAGCAATCGACACAGCCAACAATggccacaacaaccacagcagcagcagtgccagcGACAACAGTTGCCACGCcccttctgcagcagcagcagccggtgATTGTGGCGAGCAACTCTCCGGCCGAGAAGCCGGGCCGCTATGTGTGCCCCTACTGCAACATGAGCTGCGCGAAGCCCTCCGTGCTGCAGAAGCACATTCGAGCGCACACCAACGAGCGGCCGTATCCCTGCGACACCTGCGGCATCGCCTTCAAGACGAAGAGCAACCTCTACAAGCACTGCCGCTCCCGCTCGCACGCCGCCCGCATGCGCGGCTTCGACGTGCCCGCCAACGAGGCCGACGGCCTCTCCGACCaggacggcgacggcgagctcagcaacagcagctccgAGCTCCTCAGCGTCGAAGTGCTTAGCCGCGCAGAGTCGCCATACGAGGACTCGATGGCCTCGCCAACGCCCTCGCCCTCGACGCTGTCGGCGGCGAAGAGTCTGTacctgcagcagccgccgctgccgcagcacatgcaacagctgccgctgggcTCGCCGGCGGCCGgcacgctgccgccgcccaccaCCGACACGCTGCACTCGGCGACGGCGCAGCACCGCCAGTCGATCGACTACAAGCCCTACAAGCCCAAGTTCCACAACGCGGGCCTCTACGTgcccgccagctgcagcaaggagcagcaggtgcagctgcaagtgctgcagcagcagcaacaccagcaggccctgcagcagcaacagcaacaacagcagcagcagcagcagaagttgttgtcacagcagcagcagcagcaaccaacgTTGGCGCATCCGACGCTGTCGCCGAGCACACAGCTGAAGCTGAACAATCACATCAACTCGCAccagatgcagctgcagctgcaacaccagcagcaacagcagcagctgcacgcaCAGCAAtcactgctgctggctgccgccaATCCCGCTGCACTCGGCGCACTGCCGCCCCCGCCGGCCATGCCCACGAGCGTCTACTTCCTCGGGCAGCCGCAGTACTTCAATCCGGCGACGGCAGCCATGCACCAGCAGGCGCTCGCCTTCCAccagatgcagctgcagcagcacctccagctgcagcagcaacactcgCCGCTGCTCAAGGCGCCGGCGCAtcagccgccgccaccgccgcagccgcaggcGCCGCCCatgccgcagccacagcagctGATGCGTTCCaccagccaacagccagcagcaacgacggcggcgacgtcgctgccagcgcctgccacgcccacgccagCCGCCAATCTGAGCAGCTtcgccagcgccagcggcggcaTGCAAGTGAATGTGGAGAAGGTGCAGGAGCACATCTCGAAACTGATCTCACAGAACGAGGCCATAGTGGAGAACAAGGAGATACTGCTGCAGAAGAAGTACCCCAAGCAGCTGAATCGATCGCGCAGCttcaacaacgccaacaacaacagcggcagcagcagcagcagcagcaacaacagcagcaacgtcaaTGCGAGCAACACAAGTGGCAACAATGCGGCGCAGCTCGGCGAGACGAAGGTGAACCTAGCGCAGGCCATCGTGCAaaagcagcaccagcagcagctgcagcaacaacagcagcagcagcaacagtttctgcagcagcagcaataccAGCTgtacttgcaacagcagcaacagcagcagcagcagcacttggaGCCCGCGAATGGGCTGctgaagcgcagcagcagcggcttgGCTAGCTATGCGCTGaaggccacgcccacgcccacagcgccgacgacgccgctgagcagcggcaagctgcagccacagctgccgccgccgccgtcgccgctgccgctgcaaacGCTGCAGTACCGCCAGGATCCCGCCACGCCCGTGCCCAAGCTGGAGCCGCAGACGACGCCCAATCACGTGCAGCCGCTCAACCTCTCCGCCAAGCCCAAGCTGGCGGCGCCACCAAAGCCCGCAGCTGTcagcgtggcagccacaacagcgaCGCAGAGTGTggccacaacgacgacggccaCGAAGAGCACGGcgagcagcgcacagcagcagccgcagcagcagcagccgaacaACTCGATCATCAAGAACCTGCTGCTGAATGCACGCGGGCTGGCGGTGCCCATCGGGGAGGGCGACGACGCCGTCTACTCGTGCCCCATCTGCGCGAACGAGTTCCGCAGCGCCGACGAGCTGAAGCTGCACAACAGCACCTACTGCCAGgacgcgagcagcagcgcgccCATGAGTCCCGCCTCGTCGCCCAGCAGCAAGTACTTTCGCTCCAACTCCATATCGTTCAGTCTGCCCGAGCTCAAGTCGCACATGGCCAACTCGAAGAATCCGCTCTCGCTGGCCAAGCTCGCGTGGTCGCAGCTCAAGACGAAGCCCAGCAGCCTCGTGCTGAGTCGCCTCAGCGCCGCGCAGTCTCCCGCGCGCACCTCCACAGTGACCGCAAgtagcagcagtggcagcaacagtggctGCAACAACGTGCAGCCGCCCAGCATCGATGCCAGCAGCGTGGCGCTGCGGTTCGTGGAcgcgccgctgccgtcgcccgGGCCGCTGCTGGGCAAGACGCCGCTGGTGGACTACGCGGCGCCGCGCAAGACGCAGGACACACAGGTGGTCATCACCAAGATGCACGAGGATCGCGTCGAGAACATCATCGTCGAGGCGCCCGCCAAGCGCGCCAAGCTCAGCGCCGATctgccgagcagcagcggcagcgccttTGCGCTGCCCTCCaacgtgcagctgcagctgttcaGCGGCAACCAGGAGCTGCAGCCCACCAGCAGTGGCAAGGAGGAGCGGCTGCGTCGCTTCACCTCGTCGGGCGGCACCATGATACCCATCTCGGAGTGCCCCGAGTTCAGCAACAGCCCCAAGATGATACGCACGCCGCTGCTCTCGGGCGGCAGCTTCCAGGAGATGTCGCCCCGCCCCGGCGACGCCAAGGAGCGCAAGCTGCCCGCCACGCCCAGCAACAACGGCTTCCTGGTCAGCGCcagcgcgacgacgacgccgcagCACTTTCAGTTTCCGCCCATCAACTCGATCACCGCCTTCAACCCGCTCACGCTGCCGCCCATGAGCAGCTCCGGCGTCGCCCCGCCGGACGCCAGCAAGGCCATACCCTATGTGCCCGGCATTCCGGGTCCCGGCAGcctctcgctgctgccgccgccacagcagctgcagcgcggtCGCAGCCCCAACCGCAAGCAACCCAGTCCCAATGCCTTGTCGCCGTTCGGCGGCGTTCAGAACCTGCCCAGCGAGTTCAGTCGCCAGCCGCCGACGCCGGCGCAACGCAATGCGCTGCAGTGGAGCAAGACGACgccggcgacagcgactgcgacagcggcagGCGGGACGGCGAAGCAGCAGCCGTTCAACTTCCTGCGCATGGCCGACAATCTGAAGCTGGCGCCGGAGCAAACGGcgcagccagcgccagcgccggAGGTGCGGCACTTCAACTTCGACAACGTGCACAAGCCGCAGCAGGAGGCGCTGGCGCCTCTGCACGTCGACACGCCCGAGGAGGGCGCCAGCGTGGCGccaacagcggcagccgcaacgCTGAGCACGTCGAGCGCCAAGTCGAAGTTCCTGCGTCCCACCAGCCTGCCGCTGAAGCCGGGCACGTTCACGCCGAAGCGGCACCACGGCATCACGCCGACGGCGAACACGCTGCCGCTGATCTCGCCGGAGACGCCGCGACCCTCGAAGTCGTGCGTGCAGCTGTACCTCAACGGGCACGCCTACACCTACCTGGGGCTGAAGTGCAGCACCAAGATGTTCTACTGCACGGTGAACTGTCCGCAGCCGTCGTACGTCGCCGGCATGCACAAGCTGTCGATGTACAGCGTGTGGCAGGTGTGCGAGGAGAACCAGCCGCATCCGCTCGGCTTCAAGCCCAAGCAGGTGATGGCGCTCTACGACTCGCGCCAGAAGCTCCTCGGCAGCGGCTCCTCCATGGCCCAGTCCGGCGCCGGCCAGCTGCTCTACACCGTCGTCGGCTCCCAGCGCACCGTCAGCACCTGCTCGACCACCGCCAACGGCCACAGCAAGTTctaccagcaccagcagccgcagcagcagcagcagcagctgaagcccGCCACGCCGGCGATCGCCGCGCTCAGCGAGGCGAATGTGGCGGCCAAGGCGAGCGAGGAGGCGGCCGCCAAGAAGCTGGAGACCGGCCAGCTGCTCGTCGGCGGCTACGAGTCGCACGAGGACTACACGTACATCCGGGGACGCGGCCGCGGTCGCTACGTCTGCTCCGAGTGCGGCATCCGCTGCAAGAAGCCCTCCATGCTCAAGAAGCACATTCGAACCCACACCGACGTGCGCCCCTTCACCTGCAGCCATTGCAACTTCAGCTTCAAGACCAAGGGCAACCTCACGAAGCACATGCAGTCGAAGACGCACTTCAAGAAGTGCATCGAGCTGGGCATTAACCCGGGCCCCATGCCCGCCGACGGCGACTTCCTCGACGTGGACGTGGAGTTCGACCAGCAGTCGTCGACCTCGGCGGGCGGCCGCACTTCCTCGATGGCCGGCGAGTCCGACTCTGACGACTACAGCGACAACGAGTCCGAGAGCAGCGACACCGACGAGTCCAAGTCGCGGCAGAAGGAGCACGAGGCGGCGCGCGgtctgctgtcgctgtcgatgacGCCGCCCATTCCGCAGAGCGTCTCGCCCTATTCCGCCCAGCTGCAGGACACGCCCCTGCCGGCCGCCAGTCCGGCCAACAGCATTGGCTCCTCGGCGGGCAGCGCAgggggaggcggaggcggcggcggcggcggctcgCAGCCCAAGCGGCTGGTGTGCTCGTTCACGTCGCCGAAGCCGCCGTTCGACTACCAGAAGCAGGAACAGTATTACTCCAATCCCGAGGAGTCGAAGCCGAAGCGCGGCGTGCCCAGCGACGAGAGCAGCGCGCCCATGGACCTGACCAAGCCGcgctccgcctcctcctcctcctcctcctcgttggCTGTCTCGATTGCAATTGCGATCGCGCCGCCCGTGGAGCAGCAGACGCTGCCCAAGTCGCAGGCGCAGCAGATGCGCGATGTGATCTTCGGGGCGGGCAACAACGAGTGCGGCTTCATGAAGACCCTCATCTCGGTCTCCGACAAGGTGCGCATCTCCGCCGAGATGGAGGAGCAGGCCAAGCGCGACACCGAAGCCAGCGCCACCGGCGGCGGGGGGGatgatgtgctgctgcagacCTACATCAaggagcaggcgctgcagtACGCCAAGATGAAGCAGAGCCAGTACAGTCGCAGCTACTTGGCAGGCAGCACTAGCCTCATCAccacgaccagcagcagcagcggcagcggcgcgaCGACCTTGgtgagcagccagcagaagcCGCTGCTGATCACGGAGCTGCCACTCATCGAGGTGCACGGGGTGCAGACGCCCGAGGCGGAGACGGCGCCACAGCTGCCAGtcgaggagcaggaggaggccAAGACCACGCCCCACGAGCCcgagcagccagctgccagcccagcagcggcagtcgcgacgcagccagagccacagtcgcagtcgcagccacagccacagctgcagcacaatgcCAATCTGCCGGCGGCTGTGCAGCAGCCGGACGCCAACGACTTCAGCGGCGTGCTGGGCGGCAGCAatgcagcgacggcggcagcgacggcggcacgCAACGTCATCGTGGGCGAGGAGGGCTTCAAGACGACGCCGCCAGCGCCCGCCACGAGCAGCGCGCCAGCAGAGCTGCCAGTGGCCGCCGTCTCTGTGGccgtgtccgtgtctgtgtcGGTGGCAGGCTCGGGCAGCTTTGCGGGCCGCGTggggccgccgccgccgccgccgatgGCGAGCGATGCGCGACCGACGTGCAGCATCTGCAACAAGCAGTTCCAGCGGCAGCACCAGCTGACGCTGCACATGAACATCCACTACATGGAGCGCAAGTTCAAGTGCGAGCCGTGCAGCATCTCGTTCCGCACGCAGGGCCACCTGCAGAAGCACGAGCGATCGGAGGCGCACAAGAACAAGGTGATGATGACGTCGACGTTTGGGGTGCCGACCACCTCGAATCCGCGGCCCTTCGAGTGCACCGACTGCAAGATCGCGTTCCGCATACACGGCCACCTGGCCAAGCATCTGCGCTCCAAGACGCACGTCCAGAAGCTCGAGTGCCTGCAGAAGCTGCCGTTCGGCACCTACGCGGAAATCGAGCGCGCCGGCATCAGTCTGACGGAGATCGACaccagcgactgcgacaatTCGCTCATCTCGCTCAAGCTGCTCGCGCAGAAGCTGCTCGAGAAGGACCCCAACAAGCTCAGTGGCTACACGACGCCCTCGGgcatgctgcagctgggcggcgACGCGCCGGCCGCCGGCCAGGACAGCGCCTCCGAGGACGGCTTCAGTGCGGCCAACAGCGCGGCGGCCTCGGCTATCGCCTCGCTGGACAACGACAGTGCAGGGAACACGCCGCAGCGCGCCAGCTCGATGAGCGAGGACGAGACGCTGGCCAACGGACTGAGCCACAGCCTGAAGCGTCGCCTGCccggcagcagcttcagcagcaacGGTGACGAGAGCGACAATCCGCTCGACGGCGCCGAGAAGCGCCCGCGCACCAACACCAACGAACTCAATCTGCCAGCGgttgcgacggcgacggcggcggcgacggcggcagctgtggctgcgtcTGGCGCGGCGGGCAGCAACTGA
Protein Sequence
MTLQHVASSAAAAAVDTSSNHVVAGNGSGNGTTATMAPAVASSDEAATAASIGDWTNSTNLRYLHKKFKRLASTTEAEAAVVDAVRTTSLSSNSSLSPPPVTAPSSTVATSSVPLLNGHEFASNNNNINNNNSSSVHDESHNNNNNGGKHVAAAAPRTRTPLSNSNSNNNATLSPATFAQHQQSTQPTMATTTTAAAVPATTVATPLLQQQQPVIVASNSPAEKPGRYVCPYCNMSCAKPSVLQKHIRAHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHAARMRGFDVPANEADGLSDQDGDGELSNSSSELLSVEVLSRAESPYEDSMASPTPSPSTLSAAKSLYLQQPPLPQHMQQLPLGSPAAGTLPPPTTDTLHSATAQHRQSIDYKPYKPKFHNAGLYVPASCSKEQQVQLQVLQQQQHQQALQQQQQQQQQQQQKLLSQQQQQQPTLAHPTLSPSTQLKLNNHINSHQMQLQLQHQQQQQQLHAQQSLLLAAANPAALGALPPPPAMPTSVYFLGQPQYFNPATAAMHQQALAFHQMQLQQHLQLQQQHSPLLKAPAHQPPPPPQPQAPPMPQPQQLMRSTSQQPAATTAATSLPAPATPTPAANLSSFASASGGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANNNSGSSSSSSNNSSNVNASNTSGNNAAQLGETKVNLAQAIVQKQHQQQLQQQQQQQQQFLQQQQYQLYLQQQQQQQQQHLEPANGLLKRSSSGLASYALKATPTPTAPTTPLSSGKLQPQLPPPPSPLPLQTLQYRQDPATPVPKLEPQTTPNHVQPLNLSAKPKLAAPPKPAAVSVAATTATQSVATTTTATKSTASSAQQQPQQQQPNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICANEFRSADELKLHNSTYCQDASSSAPMSPASSPSSKYFRSNSISFSLPELKSHMANSKNPLSLAKLAWSQLKTKPSSLVLSRLSAAQSPARTSTVTASSSSGSNSGCNNVQPPSIDASSVALRFVDAPLPSPGPLLGKTPLVDYAAPRKTQDTQVVITKMHEDRVENIIVEAPAKRAKLSADLPSSSGSAFALPSNVQLQLFSGNQELQPTSSGKEERLRRFTSSGGTMIPISECPEFSNSPKMIRTPLLSGGSFQEMSPRPGDAKERKLPATPSNNGFLVSASATTTPQHFQFPPINSITAFNPLTLPPMSSSGVAPPDASKAIPYVPGIPGPGSLSLLPPPQQLQRGRSPNRKQPSPNALSPFGGVQNLPSEFSRQPPTPAQRNALQWSKTTPATATATAAGGTAKQQPFNFLRMADNLKLAPEQTAQPAPAPEVRHFNFDNVHKPQQEALAPLHVDTPEEGASVAPTAAAATLSTSSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKPKQVMALYDSRQKLLGSGSSMAQSGAGQLLYTVVGSQRTVSTCSTTANGHSKFYQHQQPQQQQQQLKPATPAIAALSEANVAAKASEEAAAKKLETGQLLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGDFLDVDVEFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRQKEHEAARGLLSLSMTPPIPQSVSPYSAQLQDTPLPAASPANSIGSSAGSAGGGGGGGGGGSQPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRGVPSDESSAPMDLTKPRSASSSSSSSLAVSIAIAIAPPVEQQTLPKSQAQQMRDVIFGAGNNECGFMKTLISVSDKVRISAEMEEQAKRDTEASATGGGGDDVLLQTYIKEQALQYAKMKQSQYSRSYLAGSTSLITTTSSSSGSGATTLVSSQQKPLLITELPLIEVHGVQTPEAETAPQLPVEEQEEAKTTPHEPEQPAASPAAAVATQPEPQSQSQPQPQLQHNANLPAAVQQPDANDFSGVLGGSNAATAAATAARNVIVGEEGFKTTPPAPATSSAPAELPVAAVSVAVSVSVSVAGSGSFAGRVGPPPPPPMASDARPTCSICNKQFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCDNSLISLKLLAQKLLEKDPNKLSGYTTPSGMLQLGGDAPAAGQDSASEDGFSAANSAAASAIASLDNDSAGNTPQRASSMSEDETLANGLSHSLKRRLPGSSFSSNGDESDNPLDGAEKRPRTNTNELNLPAVATATAAATAAAVAASGAAGSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00509296;
90% Identity
-
80% Identity
-