Drub011811.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila rubida
Gene Symbol
RREB1
Assembly
GCA_035046165.1
Location
JAWNOF010000023.1:4255899-4262864[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.035 2.1 8.8 0.8 1 21 252 272 252 274 0.93
2 13 0.00033 0.019 15.2 0.2 1 23 284 306 284 306 0.98
3 13 7.9e-05 0.0047 17.1 7.3 1 23 312 334 312 334 0.98
4 13 0.14 8.3 6.9 2.5 2 20 532 550 532 552 0.93
5 13 0.0082 0.48 10.8 0.1 1 23 727 749 727 749 0.97
6 13 1.2e-05 0.00071 19.7 0.7 1 23 759 781 759 781 0.99
7 13 0.00081 0.048 13.9 2.0 1 23 787 810 787 810 0.97
8 13 0.0029 0.17 12.2 2.0 1 23 1065 1088 1065 1088 0.95
9 13 8.5e-05 0.005 17.0 0.3 2 23 1431 1452 1430 1452 0.97
10 13 0.14 8.4 6.9 6.3 1 23 1458 1481 1458 1481 0.97
11 13 1.9 1.1e+02 3.4 3.8 1 23 1620 1643 1620 1643 0.85
12 13 0.0083 0.49 10.8 0.5 3 23 1700 1720 1698 1720 0.96
13 13 0.0014 0.081 13.2 4.8 1 23 1726 1748 1726 1748 0.99

Sequence Information

Coding Sequence
atgctggccacacaacaacagcaacacacggcaacagcagcaactgttgctggcgccgcgacagcgacaacagttGCCCACAGCGATGACGGACAGAGTCTGGATGgcgagcgacagcgacgcgaTTCAACCACCTCGGAGTCGTCGCTGGAGCATCTCGACCTGGGACGCACACCAAAgaagctgagcagcagcagcggcgcgccgcagccgacgtcgacgccgcacgagacgtcgacatcgacagcgacagcgacgtcgacgtcgcgcaAACGCAAgctgcgccagcaacaacagcaacagcagcaacagttgtccGACGaagacgagcagcagccaacgcagcagcagcagctggagacaacagcgcagcgactgcgacacaAGCAGCGACGCaacgtcgctgccagcgccagcaTCGTGGGCGACTACTGCGTCAGCGGCGACGCGAGCTCGCTGCGCAAAAAGTTTCGCTTCAAtcgcagcagcgccgccaacGGCGACCTCTCCGAGTCGGGCTTCGTCGacggcagcgccaacagcggCTActtgctcagcagcagcagcggcagcggcagcggcagtggcagcgcagtcgccgtAGCCGCCgcggcagccgcagttgcagcgcagcaacagcaacagcagcagcatcagatGTCGTCGAGCAGCTCGGGCGGCTCGTCGCCCCAGGGCGGCCTGAGCTTGTCGAGCGCCGAGTCCGGCATCGGCGCCGGCGACGAGCACATGAAGTATCTGTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAGTTCACCAATCACATTCGCTGCCACAACTACGCCAACGGTGACACCGAGAACTTCACCTGCCGCATCTGCTCGAAGGTGCTGTCGTCGGCCTCGTCGCTGGATCGTCACGTGCTGGTGCACACCGGAGAGCGGCCGTTCAACTGCCGCTACTGCCACCTGACATTCACAACGAACGGCAACATGCATCGCCACATGCGCACGCacaagcagcaccagcagcagtcgcagtcgcagtcgcagtcgcagcagtcgcaacagtcgcagcagcaaccctcgcagtcacagtcgcagcagcagcgacgccagcagcaggcggcaacagcggcgagcgccacacagctgctggcggcagcggcggcggcggcggggggaCGCGCGGAGAGCTACGAGAGCGACGCCAGCTGCTCGACGGACGTGTCCAGTGCGCAgagtcacagcagcaacagcagccacaacagcagcaatcgctccctcaacaacaacaacaacagcaagctgagcaacaacaacaacaacgagctcGTCTTGGAGCTGGAGCACAAAGGCCACAAGaagatgaacaacaacaacgagatcGTGGAGCAGCAAGTGGAGGATGAGGAGGCCAGCGAGTCGGAGGTGACGCAAGTCATCACCAGCACCCCCGACGTGGCCACGCTGCTGGCGACGTCGTCGCGCTCGGGCGGCACCACGCCCACCCACCTGCTCAGCTGTCCCGCCTGCGCGGCGGACGAGTTCGAGACGCTGCCGGCGCTCTGCGAGCACCTCGACGCCCAGCACTCGGACATACCGGCCAAGTGTCGCGACTGCGACGTCATCTTCGCCAGCCATCGCCAGCTGCAGACGCACAGCTgtcgcctgcagctgctgcccctgcTCGGCGCCAGCTCCTCGCCCAAGCAGgagcgcgacgacgacgaagacgagcagcaggaggaggagcaggaggagcgcggcgacggcgacgacgacgacgacgacggcgacgacttGGACGAGGACGTGGACGAGTCGgttgcgcagcagcagagcgagcgCGACGACTTCTTTCAGCAGCTCTACCTCAAGGGCAAGTCGAGCGGCGTCCTGCTGCCGTCGCCCATCAAGCACGAGCCGGCGAccagccacaaccacaaccacaaccacagtCACAACCATAGTCATAGTcagagcaacaacgacagtcGGCAGGATCTGGCGGACATACAGAGCATACTGAACATGACCAGCTCGAGCTGCACGTCGAGTTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAGTACAGCGTGGACGggcgcgacggcgacgaggagGCGCAGGACGCCTTCACCAGCGAGTTCCGGCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGCACCGCCGTCTTTCCCAATCTGCGCGCCCTCAAGGGCCACAATCGCGTCCATCTCGCCGCCGTCGGCGCCGCCGGCCCCTTCCGCTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCGGCCCTCGTGCGGCACATGCGCACCCACAACGGCGACCGGCCGTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACCAAGGCCAACTGCGAGCGGCATCTGCGCAATCGGCACGGCAAGACCAGTCGCGAGGAGGTCAAGCGCGCCATACTCTACCATCCCGCCGAGGACGCCAGCTGCGAGGACGCCAAGTCAGCCGGCCAGCAGGAGCTCGCCGAGCTCAGCTATCGCTCTgccacgccgccgcccacactgccgcccccgccgccagAGGCGGGCAGCTCGCAGCTGAAGCACATACTGCTGGCGGAGAACGTGGCCACCGTGTCGCCCAAGATACAGGTGAAGAGTCTCGACCAGCTGGTGGAGAAGCCGACGGCGCCGCCGACGCTCGACCACAGCATGGACGTGCTCGATCTCAGCAAGAAGCCCCACGAGCTGCTCGACCAGCGCGATCGCGACAGGGAGCGGGACAGGGAGCGCGAGCgtgaacgcgaacgcgaacacgagttgctgctgcagcaacagcaacaacaacaacagcagcagcagcagcagcagctgtttggcGCCGGCGACGCGGCCACGCAGtacatgcagcagctgctgcgcaacCTGATGTTCCAGCAGCCGCCCGGCTTCCCCTTCTTCGGCTTCATGGCGCCGCCCAGcgccgccgcggccgccgccgccgtcacaGCAGCCGCGCCCGAGAAGTCGAGCGCAGGGGGAGGCGgcgcaacggcggcagcgctgccgctgccgctgcccagcgTGGGCGTGCCGATGCCCGCCGGCGGACCCGTCAAGATGGTCATCAAGAACGGCGTGCTGATGcccaagcagaagcagcgtcGCTACCGCACCGAGCGCCCCTTCGCCTGCGAGCACTGCTCGGCGCGCTTCACGCTGCGCTCCAACATGGAGCGGCAcgtgaagcagcagcatccgcagTTCTAcgcgcagcgccagcgcagCGGCCACCATGTGATGCGCGGCCGTGCCGCCTCCTccagcgccgcagcagcagcggccgcagcagcggccgcagcagcagcggcagcggcggcagccgccatggcccagcagcagcatggacagcagcagcagcagcagcatgggcAGCATCAGGGACACGCACACATCTCGGACCAGGTGAAGTACGCGATactggcgcagcagctgaaggcGCGCAAGGACAccgatctgctgcagcaggcgctggcgCACGGCTCCAGCAGCGTCGCCGGCAATCCGCTGCTGCACTTCGGCTACAAGGCGCCAgtggcgggcagcagcagtggcgccACAGTGTCGCAAGCGCCGAGCAACGGCTGTGCCGTGCTGGACGACGATGAGCCGCCCAAGCTGATCatcgacgaggacgacgacgacgacgacgacgacgacttcgaggaggacgacgacgaggagctggacgaggacgagcagctgccactcccgccgccgcctgcagtcgaagctgcagctgtggaggaggagcagccaGTCGAGCAGCCGCGGCCGCGCAGCTCGACGCCCATCGAGGCGGCCAAGAAGGTGGCCGAGACGATACTGGAGCAAGCCATCAAGGCGGGCAAGAGCAGCGTGGGTAGCGGGGAGTCGCTGGCcgagccgaagccgaagccgccGGCGCTGAAGACGCTGATCGCGCAGGCGGAGTCGGTGGGCAAGTCGCTGAAGGAGGTGGCCAGCTCGCCGTTCAAGGACGAATCTCAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCCACCAGCAACCAGGTGTCGTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTCGTCGCCTccggcagcgccagcgagagcaacaactcCGGCACCGAGGAcgtcaccagcagcagcagcaacgagccCAAGAAGAAGTCCGCCTACAGCCTGGCCCCCAATCGCGTCAGCTGCCCCTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTCACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGTCCGCTGCTCTTCACCACCAAGAGCAACTGCGACCGCCATCTGCTGCGCAAGCACGGCAACGTCGAGAGCGCCATGAGTGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATACCCGTGCCCAAGTCCGTCGAGGAGAtcgagctggaggagcagcgTCGTCGCCGCGCCGCCGAAGCCGAGCTGGAGCGCGAGCGTGAGCTGGAGCGCGAAAGGGAGCGCGAAAGGGAGCGTGAGCGTGAGCGGGAAAGGGAGCGAGAACGGGAACTCGAGCTGGAGCGAGAGCGTCgccagctggagcaggagcgcgagcagcagcagctcatccagcagctggcggcagccgcgcagctcagccagcagatggccgccgcagccgccgcagccgcgacgctgaacggcaacggcgacagcacgacggcggcggcggcggcggcagggGGCGAGGCGCAGGGCAGCGATCTGCCGTACAAGTGCCATCTCTGCGAGTACTCGTTTGCGGAGCGGCTGCAGTGCCTCGACCacatcaagcagcagcacgcgcacgagtttgcgctgctgctcgccaagGGCGCCATCGAAACAGagggcgagcagcagcagcagctgccgccgccgccgtcggcgAGCGTGGCTTCGGATGAGGAGCAGGCGGGCAATGCGGCGACACGCACCAAGTACCCGGACTACAGCAATCGCAAGGTGATCTGCGCGTTCTGCGTGCGCCGCTTCTGGTCGACGGAGGATCTGCGGCGCCACATGCGCACGCACTCGGGCGAGCGGCCGTTCCAGTGCGACATCTGCTTGCGCAAGTTCACGCTCAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGCGGACGCAGCCACAACGGCGAGCAGGGCCAGTCCGACTGCTCCGACGACGAGCAGTCCATGGCACTCAGCAGTCCGCCCggcacgcccacgcccaccaccaccaccaccaccaacaacaacaacaacaacaacaacaacacttgccacaacaacaacaacaacaacaacaacagcaatactaataacaacaacaagccgaGTCTGCGGCTGCCGAAGCTGCACGAGCTGCTGGACAAGGCGAGCGAGTGGCGCGACAGCCATCTGGGCGAGCACAAGGAGAACCTGGGCGAGGCCAGCAGCAagtccgccgccgccgccggccaggccgccgtcgcagccgctgccgctgccgccgctgcgaGCAGCGATCTGATCGGCAACCTGCTGGGCATCAGCGATCAGGGCATACTCAACAAGCTGCTCTCCTCGGCCGACGAGGCGGCCAAGCTGCTGGGCGTGGACAAGTAA
Protein Sequence
MLATQQQQHTATAATVAGAATATTVAHSDDGQSLDGERQRRDSTTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHETSTSTATATSTSRKRKLRQQQQQQQQQLSDEDEQQPTQQQQLETTAQRLRHKQRRNVAASASIVGDYCVSGDASSLRKKFRFNRSSAANGDLSESGFVDGSANSGYLLSSSSGSGSGSGSAVAVAAAAAAVAAQQQQQQQHQMSSSSSGGSSPQGGLSLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQQQSQSQSQSQQSQQSQQQPSQSQSQQQRRQQQAATAASATQLLAAAAAAAGGRAESYESDASCSTDVSSAQSHSSNSSHNSSNRSLNNNNNSKLSNNNNNELVLELEHKGHKKMNNNNEIVEQQVEDEEASESEVTQVITSTPDVATLLATSSRSGGTTPTHLLSCPACAADEFETLPALCEHLDAQHSDIPAKCRDCDVIFASHRQLQTHSCRLQLLPLLGASSSPKQERDDDEDEQQEEEQEERGDGDDDDDDGDDLDEDVDESVAQQQSERDDFFQQLYLKGKSSGVLLPSPIKHEPATSHNHNHNHSHNHSHSQSNNDSRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGDEEAQDAFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRVHLAAVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAILYHPAEDASCEDAKSAGQQELAELSYRSATPPPTLPPPPPEAGSSQLKHILLAENVATVSPKIQVKSLDQLVEKPTAPPTLDHSMDVLDLSKKPHELLDQRDRDRERDREREREREREHELLLQQQQQQQQQQQQQQLFGAGDAATQYMQQLLRNLMFQQPPGFPFFGFMAPPSAAAAAAAVTAAAPEKSSAGGGGATAAALPLPLPSVGVPMPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAASSSAAAAAAAAAAAAAAAAAAAAMAQQQHGQQQQQQHGQHQGHAHISDQVKYAILAQQLKARKDTDLLQQALAHGSSSVAGNPLLHFGYKAPVAGSSSGATVSQAPSNGCAVLDDDEPPKLIIDEDDDDDDDDDFEEDDDEELDEDEQLPLPPPPAVEAAAVEEEQPVEQPRPRSSTPIEAAKKVAETILEQAIKAGKSSVGSGESLAEPKPKPPALKTLIAQAESVGKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRRAAEAELERERELERERERERERERERERERERELELERERRQLEQEREQQQLIQQLAAAAQLSQQMAAAAAAAATLNGNGDSTTAAAAAAGGEAQGSDLPYKCHLCEYSFAERLQCLDHIKQQHAHEFALLLAKGAIETEGEQQQQLPPPPSASVASDEEQAGNAATRTKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRSHNGEQGQSDCSDDEQSMALSSPPGTPTPTTTTTTNNNNNNNNNTCHNNNNNNNNSNTNNNNKPSLRLPKLHELLDKASEWRDSHLGEHKENLGEASSKSAAAAGQAAVAAAAAAAAASSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-