Basic Information

Insect: Drosophila robusta
Gene Symbol: -
Assembly: GCA_004143805.1
Location: SCDV01000540.1:54007-55413[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 1.3 1.7e+02 3.6 2.2 1 23 232 254 232 254 0.93

2 5 5.1e-06 0.00064 20.6 3.3 1 23 260 282 260 282 0.98

3 5 0.00049 0.061 14.4 4.8 3 23 290 310 288 310 0.98

4 5 3.8e-05 0.0047 17.9 0.1 1 23 316 338 316 338 0.97

5 5 0.00013 0.016 16.2 5.8 1 23 344 368 344 368 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	1.3	1.7e+02	3.6	2.2	1	23	232	254	232	254	0.93
2	5	5.1e-06	0.00064	20.6	3.3	1	23	260	282	260	282	0.98
3	5	0.00049	0.061	14.4	4.8	3	23	290	310	288	310	0.98
4	5	3.8e-05	0.0047	17.9	0.1	1	23	316	338	316	338	0.97
5	5	0.00013	0.016	16.2	5.8	1	23	344	368	344	368	0.92

Sequence Information

Coding Sequence: ATGCTCAAAAGTACGTGTAGGGTGTGTGGCAGAAATGCAGCCTgcaaaaaatcattaaaaatctttgataataaaaatgtactttgGAGCATTCAAGTCCTTACAGGCTTAATTTTGGAAAATGCCAAATGTTTACCTGACCTCATATGTGTAAGCTGCCAGACAGAATTGCGCGAAGCAATTGGTTTTAGCGATAGAGTAATTGCAGCCCAACAACAGCTTCTGACGGCGTTGACAGACGAAGATCTGCAGGATGTGTCCGAGGAGTTCAGGATAGCTGTAATGGAGTAcgccagcaacagttgccaaaaatcaaGCAACACAAGCAATTCTGACACACAATCAGAGATAGGTGAAGAGCTTCTAATTAAAACGCAACAAAACGAAGACGAGATCGGTATAGAGGAATATGGCAAAGAGGAAGATCTGATGGAGTACGACATCATCATTGATGACGACCCAATTATACAGGAAACTGAAGCACATGTTATCCGAAGTTTCAAAACAATCGAGAATAATACTGATGAGCACCATAGTGCAATGGTCAGCGATATCAATGGCAAGGCAATTGTCGAGGATTGTATCCTGCCTGATAAAGATTTGAATGAAGAGTGTGTGGTATTGGGCAGAGCGTTGAACGAAGCGACTGCAGTCAAAAAGAAGCGAGGACGAAAACGCATCGGAAGCCTTATATACGCTTGTGAGGAATGTGGCAATCATATATCTGGACGCAAGGCCTTTGAACTACACTGCAGACGACATCGTGGAGACAAACAGTTTGAATGCGACATCTGCCAGGACCGTTTTTGCACTAGCTCCGAGTTGAAGAGCCACATGCGAAGGCACACCGGTGAACGTCCCTTTGGCTGCCATTATTGTGATCGCTGCTTCGCGGACTACAGTACACGGGTAAAGCATGAGCGGACACATACCAATGAACGGCCGTATGCATGTGCAAGCTGTGGCAAGGCCTTTACCACCGCCTACATTCTTAAGAATCACATGCTCATCCATTCCGGCGAGCGTGCCTTCAGCTGCGAGTCTTGCAATAAAACCTTCAGACGACACACGCATCTGGTTACGCATTATCGGTCCAGAGCTCACAGACGTAAACTAGAACGTCAACACAAGGAAATGATTATCAAAAGCTAA
Protein Sequence: MLKSTCRVCGRNAACKKSLKIFDNKNVLWSIQVLTGLILENAKCLPDLICVSCQTELREAIGFSDRVIAAQQQLLTALTDEDLQDVSEEFRIAVMEYASNSCQKSSNTSNSDTQSEIGEELLIKTQQNEDEIGIEEYGKEEDLMEYDIIIDDDPIIQETEAHVIRSFKTIENNTDEHHSAMVSDINGKAIVEDCILPDKDLNEECVVLGRALNEATAVKKKRGRKRIGSLIYACEECGNHISGRKAFELHCRRHRGDKQFECDICQDRFCTSSELKSHMRRHTGERPFGCHYCDRCFADYSTRVKHERTHTNERPYACASCGKAFTTAYILKNHMLIHSGERAFSCESCNKTFRRHTHLVTHYRSRAHRRKLERQHKEMIIKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567871;
90% Identity: iTF_00598473;
80% Identity: -